Navigation Links
Stem cell focus for IBD wound healing
Date:4/28/2009

Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).

The study could eventually lead to the development of new drugs which use natural molecules to spark the recovery of patients suffering from ulcerative colitis and Crohn's disease, reducing their risk of associated complications such as scarring, bowel obstructions and tumour growth.

Funded with a 118,500 grant from the National Association for Colitis and Crohn's Disease (NACC), the two-year project is being led by Professor Mohammad Ilyas in the University's Division of Pathology.

He said: "The study will focus on the molecule CD24 which is a stem cell marker and which plays a key role in cell proliferation and the migration of healthy cells to a damaged area to restore normal tissue.

"CD24 is a small molecule attached to the cell membrane which has been recently reported as a marker of stem cells in the colon. It occurred to us that CD24 might have a role to play in IBD and during further studies we found that it was indeed present in sections of diseased bowel."

IBD affects around one in 400 people in the UK. Common symptoms include inflammation and ulceration of the intestine and colon, pain, severe diarrhoea, tiredness and weight loss. The cause of the disease is yet to be definitively identified, although scientists believe it could be due to a combination of genetic predisposition and environmental factors. Currently, there is no cure and patients manage their condition with a mixture of lifestyle changes, anti-inflammatory drugs and, in severe cases, surgery.

Professor Ilyas added: "The power of the gut to heal the damage caused by acute episodes of inflammation is remarkable and frequently the gut lining reverts to normal. Anti-inflammatory drugs help this process along and allow the wound healing
'/>"/>

Contact: Professor Mohammad Ilyas
Mohammad.Ilyas@nottingham.ac.uk
44-011-582-30735
University of Nottingham
Source:Eurekalert

Page: 1 2

Related biology news :

1. Supply Chain Council Seminar Focuses on Defense and IT
2. Supply Chain Council Seminar Focuses on Defense and IT
3. Recession Puts Focus on Business Optimisation and Excellence to Strengthen Business Core
4. Human aspects of climate change to be focus of conference at Illinois
5. While focusing on heart disease, researchers discover new tactic against fatal muscular dystrophy
6. New text focuses on formidable opportunistic fungus
7. GEN reports growing focus on PI3-kinase pathway in cancer research
8. ESA satellites focusing on the Arctic
9. Endangered sawfish focus of national collection and recovery efforts
10. 15-state Southern obesity summit to focus on deadly epidemic
11. Research conference at UH to focus on US troops needs, homeland security
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... found clownfish larvae can swim up to 400 kilometres in ... cope with environmental change. , Clownfish spend their entire adult ... babies they must wander the open ocean, says study co-author, ... Coral Reef Studies (Coral CoE) at James Cook University. , ... now we,ve been given a rare glimpse into how far ...
(Date:9/17/2014)... creation of the Santa Ana Wildfire Threat Index ... of the powerful, hot, dry Santa Ana wind, which ... was introduced Sept. 17 by the U.S. Forest Service, ... Electric. , The index includes four classification levels ranging ... help fire agencies and other emergency responders, the media ...
(Date:9/17/2014)... Europaea started in 2000 as an EC-FP5 four-year project, ... of steady progress and successful participations in several EC ... Biodiversity Observation Network project (EU BON), to increase ... contributors and to extend the general dissemination of the ... has applied its novel e-Publishing tools to ...
Breaking Biology News(10 mins):Nemo's epic journey to find a new home 2UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2Contributions on Fauna Europaea: Data papers as innovative model on expert involvement 2
... a paper published this week in the Proceedings ... aquatic ecologist Dr. Emma Rosi-Marshall and colleagues report that ... proteins that originate from adjacent genetically modified crops. The ... stalks, and plant parts are washed into stream channels. ...
... and global contributions to clean water and environmental causes, ... to invention and the pursuit of discovery, Professor Xiaoguang ... Stevens Institute of Technology at the university,s annual Convocation ... professor in the Charles V. Schaefer, Jr. School of ...
... Elevated concentrations of nitrogen and phosphorus, nutrients that can ... the same or increased in many streams and aquifers ... a new national study by the U.S. Geological Survey. ... assessment to date of nitrogen and phosphorus in our ...
Cached Biology News:Insecticides from genetically modified corn present in adjacent streams 2Prof. Xiaoguang Meng receives honorary master of engineering from Stevens 2Prof. Xiaoguang Meng receives honorary master of engineering from Stevens 3Elevated nitrogen and phosphorus still widespread in much of the nation's streams and groundwater 2Elevated nitrogen and phosphorus still widespread in much of the nation's streams and groundwater 3
(Date:9/19/2014)... (PRWEB) September 19, 2014 Cereal ... food industries will gather October 5–8, 2014, for ... Rhode Island Convention Center in Providence, Rhode Island. ... the work of food scientists, chemists, microbiologists, nutritionists, ... and food production management. To date, 1,000 attendees ...
(Date:9/18/2014)... BELLINGHAM, Washington, USA (PRWEB) September 18, 2014 ... of Representatives of a bill designed to stimulate development ... high-value jobs is being praised by leaders of ... The bill, the Revitalizing American Manufacturing and Innovation (RAMI) ... vote. The bill’s authors have said they are optimistic ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 A novel ... an MRI scanner is currently being tested as part ... Women's Hospital in Boston with the aim of determining ... can make prostate cancer biopsies faster, more accurate, less ... system also has the potential to deliver prostate cancer ...
(Date:9/18/2014)... D.C. (PRWEB) September 18, 2014 On ... Durbin and Sen. Jim Risch for National Lab Day ... projects from across the national laboratory system. Durbin and ... which aims to increase awareness of the reach of ... technologies and discoveries to address some of our nation's ...
Breaking Biology Technology:Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 2Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 3Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 4Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 5Worcester Polytechnic Institute Participates in Clinical Trial for MRI-Compatible Robot Designed to Improve Accuracy of Prostate Cancer Biopsies 6Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3
... (Amex: CPD ) announced the resignation as a ... appointment as a Director of the,Company of Gurpartap ("GP") ... the Company, effective July 22, 2008., Prior to ... July 2007, Mr. Singh served as Vice President - ...
... new CEO,Andrew Witty comments on GSK,s second quarter results while ... The new strategic priorities for GlaxoSmithKline ... Deliver more products of value - Simplify GSK,s operating ... on, http://www.cantos.com . It,s free to view. All you need ...
... retraction needed for surgical ... ... the market availability of the SlimFuse(TM) Anterior,Cervical Plate System. This innovative ... clinical needs of,anterior cervical discectomy and fusion (ACDF) surgery., SlimFuse(TM) ...
Cached Biology Technology:Caraco Pharmaceutical Laboratories, Ltd. Announces Resignation from Board of Directors of Jitendra Doshi and Appointment of GP Singh Sachdeva 2Pioneer(R) Surgical Technology, Inc. Announces the Market Launch of the SlimFuse(TM) Anterior Cervical Plate System 2
EDTA, tetrasodium salt, 1 kg. Ethylene diaminetetraacetic acid.Dihydrate. Assay: 99-101% (as is).Risks: 36, 37, 38 ; Safety Precautions: 22, 36, 37. Category: Nucleotides & Enzymes & Biochemicals, Ul...
Hybridization cassette for one slide...
... Tissues are selected tissues from mouse, rat, ... embedded in paraffin, sectioned and mounted onto ... are ready for use in tissue RNA ... tissue slides are suitable for in situ ...
MHC Volumes 1 & 2...
Biology Products: