Navigation Links
Stem cell focus for IBD wound healing
Date:4/28/2009

Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).

The study could eventually lead to the development of new drugs which use natural molecules to spark the recovery of patients suffering from ulcerative colitis and Crohn's disease, reducing their risk of associated complications such as scarring, bowel obstructions and tumour growth.

Funded with a 118,500 grant from the National Association for Colitis and Crohn's Disease (NACC), the two-year project is being led by Professor Mohammad Ilyas in the University's Division of Pathology.

He said: "The study will focus on the molecule CD24 which is a stem cell marker and which plays a key role in cell proliferation and the migration of healthy cells to a damaged area to restore normal tissue.

"CD24 is a small molecule attached to the cell membrane which has been recently reported as a marker of stem cells in the colon. It occurred to us that CD24 might have a role to play in IBD and during further studies we found that it was indeed present in sections of diseased bowel."

IBD affects around one in 400 people in the UK. Common symptoms include inflammation and ulceration of the intestine and colon, pain, severe diarrhoea, tiredness and weight loss. The cause of the disease is yet to be definitively identified, although scientists believe it could be due to a combination of genetic predisposition and environmental factors. Currently, there is no cure and patients manage their condition with a mixture of lifestyle changes, anti-inflammatory drugs and, in severe cases, surgery.

Professor Ilyas added: "The power of the gut to heal the damage caused by acute episodes of inflammation is remarkable and frequently the gut lining reverts to normal. Anti-inflammatory drugs help this process along and allow the wound healing
'/>"/>

Contact: Professor Mohammad Ilyas
Mohammad.Ilyas@nottingham.ac.uk
44-011-582-30735
University of Nottingham
Source:Eurekalert

Page: 1 2

Related biology news :

1. Supply Chain Council Seminar Focuses on Defense and IT
2. Supply Chain Council Seminar Focuses on Defense and IT
3. Recession Puts Focus on Business Optimisation and Excellence to Strengthen Business Core
4. Human aspects of climate change to be focus of conference at Illinois
5. While focusing on heart disease, researchers discover new tactic against fatal muscular dystrophy
6. New text focuses on formidable opportunistic fungus
7. GEN reports growing focus on PI3-kinase pathway in cancer research
8. ESA satellites focusing on the Arctic
9. Endangered sawfish focus of national collection and recovery efforts
10. 15-state Southern obesity summit to focus on deadly epidemic
11. Research conference at UH to focus on US troops needs, homeland security
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2015)... --  HOYOS Labs , a leading global authentication infrastructure ... Company will demonstrate multiple biometrics-based technologies under its identity ... on March 23 through 25, 2015, in ... IEEE Biometric Open Protocol Standard; free biometrics-based consumer app, ... system. BOPS was invented by HOYOS Labs and contributed ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/4stcg3/india_sensors ... "India Sensors Market Forecast and Opportunities 2020" ... market is projected to grow at a CAGR ... automotive, industrial and healthcare sectors are the key ... addition, adoption of MEMS technology in sensors is ...
(Date:3/20/2015)... , Mar. 19, 2015 Research and Markets ... "Iris Biometrics - Global Strategic Business Report" report to ... for Iris Biometrics in US$ Thousands. The report provides separate ... Japan , Europe , ... , and Latin America . ...
Breaking Biology News(10 mins):HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5
... develop standards for sharing information collected by sensors and ... Taylor and Amit Parashar of CSIRO,s ICT Centre are ... Sensor Network incubator group. The incubator group is ... and a new standard to enable sensors to interact ...
... weeds to move south by up to 1000km, according to ... Weeds cost Australia more than $4 billion a year either ... the environment. In an address today in Perth ... Dr John Scott, said, however, that those cost estimates were ...
... 3rd Annual Research Awards were announced at an awards ... was attended by shortlisted authors, eminent researchers from around ... The Research Awards, now in their third year, ... accessible by open access publication. The Awards celebrate the ...
Cached Biology News:Climate change may wake up 'sleeper' weeds 2Open access research celebrated 2
(Date:4/23/2015)... 2015 Glemser Technologies ... EMC® Enterprise Content Division (ECD) Certified Solution Partner ... Documentum® for Life Sciences Solution Suite . The ... capabilities to provide life sciences companies of all ... The EMC Documentum Solution Suite offers four modules: ...
(Date:4/23/2015)... 2015 /PRNewswire/ - Crystal Research Associates, LLC announced today ... (EIO) on Aeterna Zentaris Inc. (NASDAQ: AEZS ... Crystal Research Associates, website at www.crystalra.com ... www.aezsinc.com . Aeterna Zentaris ("Aeterna" or ... in oncology, endocrinology, and women,s health. With a focus ...
(Date:4/22/2015)... April 22, 2015  Sangamo BioSciences, Inc. (NASDAQ: ... results and accomplishments. For the first quarter ... loss of $5.3 million, or $0.08 per share, compared ... per share, for the same period in 2014. As ... equivalents, marketable securities and interest receivable of $226.1 million. ...
(Date:4/22/2015)... , April 22, 2015 Steep Hill, ... announced today that it has opened an investment ... growth and expansion.  The common stock investment round ... 506(c), a law intended to encourage funding of ... to 506(c), small businesses largely relied on friends ...
Breaking Biology Technology:Glemser Earns Accreditation for Life Sciences Solution Suite 2Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 2Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 3Sangamo BioSciences Reports First Quarter 2015 Financial Results 2Sangamo BioSciences Reports First Quarter 2015 Financial Results 3Sangamo BioSciences Reports First Quarter 2015 Financial Results 4Sangamo BioSciences Reports First Quarter 2015 Financial Results 5Sangamo BioSciences Reports First Quarter 2015 Financial Results 6Sangamo BioSciences Reports First Quarter 2015 Financial Results 7Sangamo BioSciences Reports First Quarter 2015 Financial Results 8Steep Hill Launches $5M Limited Stock Offering 2Steep Hill Launches $5M Limited Stock Offering 3
... available in German . , For quite ... has also been considered the building material of choice for ... the Ruhr University in Bochum has now made a dodecahedron ... As reported in the journal Angewandte Chemie, these objects are ...
... building a clean, efficient, hydrogen-powered car is how to ... a reasonable driving range would require either impractically high ... liquid hydrogen. In a new paper* researchers at the ... Research (NCNR) have demonstrated that a novel class of ...
... $500 million in Synergies from OBS Acquisition Rolled ... 2008 ,Schering-Plough Corporation (NYSE: SGP ) announced ... reduce and avoid costs and,increase productivity to generate ... and synergies., The targeted savings represent approximately ...
Cached Biology Technology:Nanosoftball made of DNA 2More solid than solid: A potential hydrogen-storage compound 2Schering-Plough Launches Productivity Transformation Program To Confront New Challenges 2Schering-Plough Launches Productivity Transformation Program To Confront New Challenges 3Schering-Plough Launches Productivity Transformation Program To Confront New Challenges 4Schering-Plough Launches Productivity Transformation Program To Confront New Challenges 5Schering-Plough Launches Productivity Transformation Program To Confront New Challenges 6
Microlite 1+ 1x12 Strip assembled, flat bottom; the ideal vessel for low signal luminescent reactions, offering medium binding with enhanced dynamic range, extra high reflectivity and minimal cross t...
... the ultimate tool for both microplate ... are two editions of SkanIt Software ... working in life science research, and ... needed for compliance with FDA's 21 ...
... a highly purified preparation of the catalytic ... which recognizes the identical cleavage site as ... enzymatic activity. Novagen&'s enzyme is produced in ... yield the highest activity available, and is ...
... The Universal Vacuum System UVS400 is a ... The UVS400 combines a refrigerated vapor trap ... a single integrated unit. The easy-to-use, wide-mouth ... solvent into single jar for easy disposal. ...
Biology Products: