Navigation Links
Stem cell breakthrough gives new hope to sufferers of muscle-wasting diseases
Date:3/5/2009

An experimental procedure that dramatically strengthens stem cells' ability to regenerate damaged tissue could offer new hope to sufferers of muscle-wasting diseases such as myopathy and muscular dystrophy, according to researchers from the University of New South Wales (UNSW).

The world-first procedure has been successfully used to regrow muscles in a mouse model, but it could be applied to all tissue-based illnesses in humans such as in the liver, pancreas or brain, the researchers say.

The research team, which is based at UNSW and formerly from Sydney's Westmead Children's Hospital, adapted a technique currently being trialled in bone marrow transplantation. Adult stem cells are given a gene that makes them resistant to chemotherapy, which is used to clean out damaged cells and allow the new stem cells to take hold.

A paper detailing the breakthrough appears in the prestigious journal Stem Cells this week.

The ability of adult stem cells to regenerate whole tissues opens up a world of new possibilities for many human diseases, according to the lead authors of the paper, Professor Peter Gunning, Professor Edna Hardeman and Dr Antonio Lee, from UNSW's School of Medical Sciences.

"The beauty of this technique is that chemotherapy makes space for stem cells coming into muscle and also gives the stem cells an advantage over the locals. It's the first strategy that gives the good guys the edge in the battle to cure sick tissues," Professor Gunning said.

"What has been the realm of science fiction is looking more and more like the medicine of the future," he said.

The procedure solves one of the major hurdles involving stem cell therapy getting the cells to survive for more than an hour or so after inserting them into damaged tissue.

"In muscle, most stem cells die in the first hour or are present in such low numbers that they are not much help," Professor Gunning said. "Until now, the
'/>"/>

Contact: Steve Offner
s.offner@unsw.edu.au
61-293-858-107
University of New South Wales
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mount Sinai Hospital researcher makes stem cell breakthrough
2. World breakthrough in treating premature babies
3. Key to future medical breakthroughs is systems biology, say leading European scientists
4. Researchers make breakthrough in the production of double-walled carbon nanotubes
5. Fly guy makes memory breakthrough
6. A scientific breakthrough on the control of the bad cholesterol
7. Adult stem cell breakthrough
8. NC State finds new nanomaterial could be breakthrough for implantable medical devices
9. Sandia, SES win Popular Mechanics Breakthrough Innovator Award
10. Breakthrough optical technology to assess colon cancer risk, accuracy
11. Chips are down as Manchester makes protein scanning breakthrough
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... release is available in German . ... players in the natural nitrogen cycle on Earth and ... bacteria were thought to depend on nitrite as their ... by Holger Daims, a microbiologist at the University of ... hydrogen as an alternative source of energy. The oxidation ...
(Date:8/29/2014)... twist them, fold them: modern materials that are light, ... as artificial skin or electronic paper. , Making such ... but a new way of working with copper nanowires ... , Previous success in the field of ultra-lightweight ... precious gold and silver nanowires. , By turning ...
(Date:8/28/2014)... handful of bacterial culprits that may drive inflammatory bowel ... using patients, own intestinal immune responses as a guide. ... journal Cell . , Trillions of bacteria exist ... role in the development and progression of IBD. Yet ... species affect a person,s susceptibility to IBD and its ...
Breaking Biology News(10 mins):Hydrogen powers important nitrogen-transforming bacteria 2Hydrogen powers important nitrogen-transforming bacteria 3Copper shines as flexible conductor 2Yale study identifies possible bacterial drivers of IBD 2
... A team of Howard Hughes Medical Institute (HHMI) scientists has ... able to turn off genes selectively to control critical events ... molecular images of the structure of Dicer, an enzyme that ... which is reported in the January 13, 2005, issue of ...
... geochemists from the University of Southern California and Rice ... that could power spy drones that fit in the ... long been interested in micro-scale air vehicles ?some as ... the lack of a suitable, compact power source. With ...
... regenerative medicine, researchers at Rice University have discovered a new ... that the cells themselves produce a growth matrix that is ... appears online this week in the Proceedings of the National ... science ?researchers found they could coax bone cells into produce ...
Cached Biology News:Molecule does more than slice and dice RNA 2Molecule does more than slice and dice RNA 3Molecule does more than slice and dice RNA 4USC, Rice to develop bacteria-powered fuel cells 2Findings advance use of adult stem cells for replacement bone 2
(Date:8/28/2014)... New York, NY (PRWEB) August 28, 2014 ... has renewed its long term partnership with PTI ... to provide clients with state of the art leak ... state of the art instruments currently available. As part ... a new High Voltage Leak Detection Instrument ...
(Date:8/27/2014)... Austin, TX (PRWEB) August 27, 2014 ... $6 million in Series B funding and secured Otter ... and investment capital will accelerate commercialization of GGI’s Agriplier™ ... multiple crop types. , “Since our first meeting, ... commitment to the biological product space,” said Alan Sobba, ...
(Date:8/27/2014)... California (PRWEB) August 27, 2014 ... (LLNL), through Lawrence Livermore National Security LLC ... to develop and deliver a state-of-the-art laser system ... facility (ELI Beamlines), under construction in the Czech ... performance, the laser system, called the " High ...
(Date:8/27/2014)... Aug. 27, 2014   MSC , a healthcare ... today announced the appointment of Mary Beth Loesch ... 28 years of experience preparing companies for rapid growth ... Executive Vice President of Corporate Development and Healthcare. In ... business , as well as corporate strategy and marketing. ...
Breaking Biology Technology:Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 2Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 3LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3MSC names Mary Beth Loesch President and CEO 2
... Force, a web based CTMS (Clinical Trial Management ... selected and deployed Clinical Force to manage worldwide ... Regulatory/Ethics Management, CRF Tracking, Visit Reports, and Site ... Future phases of our project will include integration ...
... Inc. (Nasdaq: IDIX ) announced today that management ... programs at the Canaccord Adams Hepatitis C Conference on Tuesday, ... Barclay New York Hotel in New York City.The live and ... of Events" in the Idenix Investor Center at ...
... YORK, April 3 /PRNewswire-Asia-FirstCall/ -- China Agri-Business, Inc.,(OTC ... products through its operating company in China, announced ... , Revenue for the ... of 3.8% as compared to $3,037,414 for the ...
Cached Biology Technology:Gemin X Pharmaceuticals Selects and Deploys Clinical Force CTMS 2Gemin X Pharmaceuticals Selects and Deploys Clinical Force CTMS 3China Agri-Business Announces 2008 Operating Results 2China Agri-Business Announces 2008 Operating Results 3China Agri-Business Announces 2008 Operating Results 4China Agri-Business Announces 2008 Operating Results 5
... a chemically modified form of AmpliTaq® DNA ... to the enzyme, the enzyme is inactive. ... thermal cycling (when the reaction is going ... inactive. The result is that mis-primed primers ...
A robust formulation of Taq Polymerase supplied with a 10X colored reaction buffer which allows Direct Gel-Loading...
Ps-Aeruginosa (IgG) -Ab EIA Sample Size: 100 l...
Ps-Aeruginosa (IgA) -Ab EIA Sample Size: 100 l...
Biology Products: