Navigation Links
Stem cell breakthrough gives new hope to sufferers of muscle-wasting diseases
Date:3/5/2009

An experimental procedure that dramatically strengthens stem cells' ability to regenerate damaged tissue could offer new hope to sufferers of muscle-wasting diseases such as myopathy and muscular dystrophy, according to researchers from the University of New South Wales (UNSW).

The world-first procedure has been successfully used to regrow muscles in a mouse model, but it could be applied to all tissue-based illnesses in humans such as in the liver, pancreas or brain, the researchers say.

The research team, which is based at UNSW and formerly from Sydney's Westmead Children's Hospital, adapted a technique currently being trialled in bone marrow transplantation. Adult stem cells are given a gene that makes them resistant to chemotherapy, which is used to clean out damaged cells and allow the new stem cells to take hold.

A paper detailing the breakthrough appears in the prestigious journal Stem Cells this week.

The ability of adult stem cells to regenerate whole tissues opens up a world of new possibilities for many human diseases, according to the lead authors of the paper, Professor Peter Gunning, Professor Edna Hardeman and Dr Antonio Lee, from UNSW's School of Medical Sciences.

"The beauty of this technique is that chemotherapy makes space for stem cells coming into muscle and also gives the stem cells an advantage over the locals. It's the first strategy that gives the good guys the edge in the battle to cure sick tissues," Professor Gunning said.

"What has been the realm of science fiction is looking more and more like the medicine of the future," he said.

The procedure solves one of the major hurdles involving stem cell therapy getting the cells to survive for more than an hour or so after inserting them into damaged tissue.

"In muscle, most stem cells die in the first hour or are present in such low numbers that they are not much help," Professor Gunning said. "Until now, the
'/>"/>

Contact: Steve Offner
s.offner@unsw.edu.au
61-293-858-107
University of New South Wales
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mount Sinai Hospital researcher makes stem cell breakthrough
2. World breakthrough in treating premature babies
3. Key to future medical breakthroughs is systems biology, say leading European scientists
4. Researchers make breakthrough in the production of double-walled carbon nanotubes
5. Fly guy makes memory breakthrough
6. A scientific breakthrough on the control of the bad cholesterol
7. Adult stem cell breakthrough
8. NC State finds new nanomaterial could be breakthrough for implantable medical devices
9. Sandia, SES win Popular Mechanics Breakthrough Innovator Award
10. Breakthrough optical technology to assess colon cancer risk, accuracy
11. Chips are down as Manchester makes protein scanning breakthrough
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/6/2015)... 6, 2015 Synaptics Inc. (NASDAQ: ... solutions, today announced collaboration with Microsoft on biometric ... Microsoft leveraged Synaptics, deep expertise in human interface ... Through stringent testing, Synaptics, advanced image ... Microsoft,s Precision TouchPad (PTP) specification empowering OEMs with ...
(Date:8/5/2015)... 5, 2015 Transparency Market Research ... Market - Global Industry Analysis, Size, Share, Growth, Trends ... facial recognition is forecast to reach US$ 2,671.8 Mn ... for surveillance systems by civil and government agencies. This ... and terrorist activities across the globe that would elevate ...
(Date:8/4/2015)... 2015 Research ... the addition of the "Digital Forensics ... Sub-Segment (Computer Forensics, Network Forensics, Mobile Device ... Vertical and Region - Global Forecast to ... By Component (Hardware, Software, and Service), ...
Breaking Biology News(10 mins):Synaptics Chosen for Human Interface Co-Development on Windows 10 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... if you eat right and exercise regularly, chances are high ... But thanks to new findings by researchers from Harvard and ... unrelated studies recently published online in The FASEB ... that have the potential to save millions of lives. ...
... events such as the sudden demise of the dinosaurs 65 ... super volcanoes as culprits. But a new study, published ... that it is the ocean, and in particular the epic ... course of geologic time, that is the primary cause of ...
... viral genes tightly wound within a capsule, waiting for ejection ... revealed. Using electron microscopy and three-dimensional computer reconstruction, UC ... image yet of the protein envelope of an asymmetrical virus ... in the journal Structure . The image, with a ...
Cached Biology News:New discoveries from Harvard and Baylor get to the heart of cardiovascular disease 2New discoveries from Harvard and Baylor get to the heart of cardiovascular disease 3The mystery of mass extinctions is no longer murky 2The mystery of mass extinctions is no longer murky 3Scientists discover DNA knot keeps viral genes tightly corked inside shell 2
(Date:9/2/2015)... , ... September 02, 2015 ... ... of regulatory compliance, quality systems, analytical testing, education and consulting services for ... expertise in medical device products/processes development, design control, validation, quality assurance and ...
(Date:9/2/2015)... Research and Markets ( ... new report "Gene Therapy - Technologies, Markets and ... for gene therapy are difficult to estimate as there ... is marketed in China since ... 2014-2024. The estimates are based on epidemiology of diseases ...
(Date:9/2/2015)... 2015 Australian prostate cancer technology company Minomic ... prize recognising ,outstanding, science that uses its patented antibody. ... a novel prostate cancer diagnostic test known as MiCheck® ... taking out the peer-reviewed Australian Museum Eureka Science Prize ... This prize is awarded for ground breaking research ...
(Date:9/2/2015)... 2015 Biovista Inc. freut ... von 2015 bekanntgeben zu können. Hierbei handelt es ... Biovista unterstützt mit seiner Möglichkeit der ... anderer Krankheiten als denen, für die ein Medikament ... sein Team bei der Wylder Nation Foundation bei ...
Breaking Biology Technology:NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 2NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 3NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 4NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 5NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 6NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 7Global Gene Therapy Market Study 2015-2024 - Technologies, Markets and Companies Analysis 2Prostate Cancer Company Minomic Wins Prestigious Eureka Science Prize 2Prostate Cancer Company Minomic Wins Prestigious Eureka Science Prize 3Biovista sponsert die Forschung von Wylder Nation Foundation zum Thema Mangel an saurer Sphingomyelinase 2
... of financial technology solutions and subsidiary of Marshall and ... Virginia and Pennsylvania. , ,On Monday the company announced they ... origination solutions headquartered in Wayne, Pa. GHR was acquired for ... the third quarter of 2005. , ,Metavante said in their ...
... 18,000 people who recently attended BIO 2005 in Philadelphia made me ... its also becoming mainstream in the world economy. , ,It also ... 1960s. Though most adults at first wouldnt accept it, the launch ... a statement that rock was here to stay. So is biotech! ...
... be misleading to suggest that scientists at UW-Madison or anywhere ... fact, no scientist in the state has even announced plans ... to suggest the process for cloning a human embryo for ... from the process used in therapeutic cloning. The first step ...
Cached Biology Technology:Biotech phenomenon becoming mainstream in world economy 2Biotech phenomenon becoming mainstream in world economy 3Biotech phenomenon becoming mainstream in world economy 4Biotech phenomenon becoming mainstream in world economy 5The Attack of the Clones: No, its not a summer movie 2The Attack of the Clones: No, its not a summer movie 3
... Automatic High Sensitivity Laboratory Osmometer for 50 L samples. Operating head automatically rises at the end ... ... ... ...
Request Info...
RayBio Human Chemokine Antibody Array 1.1 (8) with Accessory, detects 38 chemokine factors (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
... cell culture chambered coverslips are ... for staining and imaging. The ... gaskets with standard optical-quality coverslips ... ready to use. Preassembled CultureWell ...
Biology Products: