Navigation Links
Stem cell breakthrough gives new hope to sufferers of muscle-wasting diseases
Date:3/5/2009

An experimental procedure that dramatically strengthens stem cells' ability to regenerate damaged tissue could offer new hope to sufferers of muscle-wasting diseases such as myopathy and muscular dystrophy, according to researchers from the University of New South Wales (UNSW).

The world-first procedure has been successfully used to regrow muscles in a mouse model, but it could be applied to all tissue-based illnesses in humans such as in the liver, pancreas or brain, the researchers say.

The research team, which is based at UNSW and formerly from Sydney's Westmead Children's Hospital, adapted a technique currently being trialled in bone marrow transplantation. Adult stem cells are given a gene that makes them resistant to chemotherapy, which is used to clean out damaged cells and allow the new stem cells to take hold.

A paper detailing the breakthrough appears in the prestigious journal Stem Cells this week.

The ability of adult stem cells to regenerate whole tissues opens up a world of new possibilities for many human diseases, according to the lead authors of the paper, Professor Peter Gunning, Professor Edna Hardeman and Dr Antonio Lee, from UNSW's School of Medical Sciences.

"The beauty of this technique is that chemotherapy makes space for stem cells coming into muscle and also gives the stem cells an advantage over the locals. It's the first strategy that gives the good guys the edge in the battle to cure sick tissues," Professor Gunning said.

"What has been the realm of science fiction is looking more and more like the medicine of the future," he said.

The procedure solves one of the major hurdles involving stem cell therapy getting the cells to survive for more than an hour or so after inserting them into damaged tissue.

"In muscle, most stem cells die in the first hour or are present in such low numbers that they are not much help," Professor Gunning said. "Until now, the
'/>"/>

Contact: Steve Offner
s.offner@unsw.edu.au
61-293-858-107
University of New South Wales
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mount Sinai Hospital researcher makes stem cell breakthrough
2. World breakthrough in treating premature babies
3. Key to future medical breakthroughs is systems biology, say leading European scientists
4. Researchers make breakthrough in the production of double-walled carbon nanotubes
5. Fly guy makes memory breakthrough
6. A scientific breakthrough on the control of the bad cholesterol
7. Adult stem cell breakthrough
8. NC State finds new nanomaterial could be breakthrough for implantable medical devices
9. Sandia, SES win Popular Mechanics Breakthrough Innovator Award
10. Breakthrough optical technology to assess colon cancer risk, accuracy
11. Chips are down as Manchester makes protein scanning breakthrough
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Ind. -- Indiana University researchers have detected new early-warning ... diabetes. This discovery could have far-reaching implications for the ... care of over 25 million Americans. , "We had ... retinas at such early stages," said Ann Elsner, professor ... and lead author of the study. "We set out ...
(Date:4/17/2014)... and plant life, but there,s an invisible machine underground. ... soil, decomposing organic matter and releasing carbon into the ... in ecological systems, their identities have only now been ... genetic map of more than 10,000 species of fungi ... in the Proceedings of the National Academy of ...
(Date:4/17/2014)... of Domestication," a special feature of The ... ( PNAS ) published April 29, raises a number ... history that most of us take for granted. At ... many spots around the globe shifted from hunting animals ... plants. , It seems so straightforward and yet the ...
Breaking Biology News(10 mins):New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3Stanford biologists help solve fungal mysteries 2Stanford biologists help solve fungal mysteries 3Genetic study tackles mystery of slow plant domestications 2Genetic study tackles mystery of slow plant domestications 3Genetic study tackles mystery of slow plant domestications 4
... shrimp-like creature at the heart of the Antarctic food ... Southern Ocean with iron stimulating the growth of ... capacity for natural storage of carbon dioxide. ... Oceanography , an international team of researchers describe how ...
... viable future biofuel especially if harvested in summer. ... could provide an important alternative to terrestrial grown biofuels; ... a seasonal basis. Harvesting the kelp in July when ... sugar release for biofuel production. , "The storage carbohydrate ...
... by women of advanced maternal age (over 35 years) ... of meiosis a critical process of chromosome duplication ... of oocytes and sperm and leading to abnormalities ... failure, pregnancy loss or, more rarely, the birth of ...
Cached Biology News:Antarctic krill help to fertilize Southern Ocean with iron 2Biofuels from the sea 2Could ovarian stimulation cause an increase in oocyte chromosome abnormalities? 2Could ovarian stimulation cause an increase in oocyte chromosome abnormalities? 3
(Date:1/15/2014)... Look inside the new Preferred Solutions® catalog ... from fluid handling to instruments to supplies. Many items ... order. , Preferred Solutions features a full selection ... model for precise flow control and dispensing to I/P® ...
(Date:1/15/2014)... , Jan. 15, 2014 ­ RedBrick Health ... behavior change technology, today announces that EmblemHealth , ... and wellness company, is now providing the RedBrick Compass ... coaching program, to all of its members. EmblemHealth is ...
(Date:1/15/2014)... 2014 More than 5 million Americans ... in 3 seniors will die with Alzheimer’s or another ... figures have shocked many Americans into looking for ways ... these tragic age-related cognitive disorders. Jonathan Weisman, president of ...
(Date:1/15/2014)... DTS Language Services, Inc . is ... for Life Science organizations who need document translations. Clients ... of their documents in advance with a selection of nearly ... translations, often a critical factor in clinical and scientific fields, ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2DTS Improves Efficiency for Life Science Document Translations 2
... India, April 21 /PRNewswire-Asia/ --,QIAGEN and the Chittaranjan ... establish the first large-scale cervical cancer screening,program for ... QGEN ; Frankfurt Prime,Standard: QIA) will provide ... the primary cause of cervical cancer. CNCI will ...
... Hoping that science will cast a spell on local ... team is starting a program that will harness the ... technical subjects resonate in local classrooms. , Funded by ... Foundation, the Innovations in Nanotechnology and NanoSciences initiative will ...
... Thoratec Corporation (Nasdaq: THOR ), a world ... support and restore failing hearts, said today that it ... FDA seeking to add the intended use of Destination ... ventricular assist system). The HeartMate II is a next ...
Cached Biology Technology:QIAGEN and Chittaranjan National Cancer Institute Partner to Establish First Large-Scale Cervical Cancer Screening Program in Kolkata 2QIAGEN and Chittaranjan National Cancer Institute Partner to Establish First Large-Scale Cervical Cancer Screening Program in Kolkata 3QIAGEN and Chittaranjan National Cancer Institute Partner to Establish First Large-Scale Cervical Cancer Screening Program in Kolkata 4QIAGEN and Chittaranjan National Cancer Institute Partner to Establish First Large-Scale Cervical Cancer Screening Program in Kolkata 5UH initiative will use 'Harry Potter' to conjure love for science in Houston-area schools 2UH initiative will use 'Harry Potter' to conjure love for science in Houston-area schools 3Thoratec Announces Filing of PMA Seeking Destination Therapy Approval for HeartMate II(R) 2Thoratec Announces Filing of PMA Seeking Destination Therapy Approval for HeartMate II(R) 3Thoratec Announces Filing of PMA Seeking Destination Therapy Approval for HeartMate II(R) 4
... monoclonal antibody raised against a partial recombinant IFNA2. ... a.a.) partial recombinant protein is produced in E. ... 8 IU/ mg. OMIM: ... Lot Number: MM951100564 MA ...
Mouse monoclonal antibody raised against a partial recombinant STAU2. NCBI Entrez Gene ID = STAU2...
Mouse polyclonal antibody to NR2F2 - nuclear receptor subfamily 2, group F, member 2...
Mouse monoclonal antibody raised against a full length recombinant YARS. NCBI Entrez Gene ID = YARS...
Biology Products: