Navigation Links
Stem cell-based bioartificial tissues and organs
Date:2/18/2013

Surgeon Paolo Macchiarini has made his name by successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material. He now plans to use the technique to recreate more complex tissues, such as the oesophagus and diaphragm or organs such as the heart and lungs. He has also made an experimental attempt to regenerate brain in mice and rats. This is part of the news he will be presenting during his seminar at the scientific AAAS Annual Meeting in Boston.

In June 2011, media all over the world reported about a ground breaking transplant, where a patient received an artificial trachea covered in his own stem cells. The result was an artificial windpipe with biological functions. To date, five operations have been carried out using this technique.

"We learn something from each operation. This means we can develop and refine the technique. We are also evaluating how we can transfer our experiences to other fields, such as neurology. The aim is to make as much use of the body's own healing potential as we can", says Paolo Macchiarini, Professor of Regenerative Surgery at Karolinska Institutet, and responsible for the surgery.

At the AAAS Annual Meeting, he will talk about how he believes the technology can be used in the future. This will include:

  • The plan to operate on a 2 year-old girl in the USA in March. The girl was born without a trachea and has lived her entire life in intensive care, where she breathes through a tube placed in the oesophagus and connected directly to the lungs. Without a new trachea, she will never be able to leave the hospital. This will be the first time the procedure is conducted on a small child. It is also the first time the procedure will be conducted on an individual without a trachea - as previously, diseased organs have been replaced.

  • There are also plans to transplant the oesophagus, an organ that is more complex than a trach
    '/>"/>

Contact: Sabina Bossi
sabina.bossi@ki.se
46-706-146-066
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related biology news :

1. Novel aptamer boosts T cell-based immune response to therapeutic vaccines
2. New technique could make cell-based immune therapies for cancer safer and more effective
3. Discovery of reprogramming signature may help further stem cell-based regenerative medicine research
4. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
5. New methods for quantifying antisense drug delivery to target cells and tissues
6. 3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
7. Long-distance solute transport in trees improved by intercellular pathways in living woody tissues
8. Tiny probes shine brightly to reveal the location of targeted tissues
9. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
10. Why do organisms build tissues they seemingly never use?
11. Penn researchers improve living tissues with 3-D printed vascular networks made from sugar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... John Essigmann and colleagues from the University of Washington had ... they could induce the virus to mutate uncontrollably, they could ... strategy that our immune system uses against many viruses. ... to mutate at an enhanced rate, as expected. But it ... clinical trial reported in 2011. In a new study, however, ...
(Date:7/28/2014)... Eight of the top 10 U.S. cities that have ... public inconveniences as frequent road closures, overwhelmed storm drains ... a new NOAA technical report. , This nuisance flooding, ... three U.S. coasts, between 300 and 925 percent since ... Nuisance Flood Frequency Changes around the United States, also ...
(Date:7/28/2014)... himself the bug hunter, but the target of his ... and identified with special methods and instruments. Benjamin Hause, ... Diagnostic Laboratory at Kansas State University, recently published an ... which is an important find in the United States. ... didn,t know what it was," Hause said. "We used ...
Breaking Biology News(10 mins):Forced mutations doom HIV 2Forced mutations doom HIV 3Forced mutations doom HIV 4NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Researcher using next-generation sequencing to rapidly identify pathogens 2Researcher using next-generation sequencing to rapidly identify pathogens 3
... Researchers at the University of Cambridge have discovered a ... within the body, a breakthrough that could lead to ... , Dr. Pietro Mastroeni, Professor Duncan Maskell at ... pioneered the integration of mathematical models with observational data ...
... had narrow, pointed teeth, which were more suited to tearing ... then grind their food? Until recently many researchers have assumed ... their muscular stomach these then acted as a kind of ... correct, as scientists at the universities of Bonn and Tübingen ...
... regulate neuronal signaling in the brain and spinal cord ... mouse with a mutation affecting a neuronal zinc target, ... modulating signaling among the neurons. Significantly, they found the ... as children with the genetic disorder called "startle disease," ...
Cached Biology News:Researchers map spread of pathogens in the human body 2Dinosaurs -- stones did not help with digestion 2Dinosaurs -- stones did not help with digestion 3Zinc plays important role in brain circuitry 2
(Date:7/29/2014)... EXpressLO LLC, expert provider of focused ... solutions, has been granted patent number 8,789,826 by the ... incorporating a unique specimen carrier support grid design described ... company patent for EXpressLO LLC awarded to founder and ... complementary patents extend EXpressLO’s portfolio of intellectual property. The ...
(Date:7/28/2014)... using light, developed by researchers at the University of ... considered the realm of science fiction, such as invisibility ... won,t be a reality for quite some time, the ... building blocks a few billionths of a metre across ... flies through them, and works on large chunks all ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 The Workgroup ... authority on the use of health IT to create ... Health Plan Identifier (HPID) Workgroup has developed an ... Health Plan and Payer?” The HPID Workgroup, a part ... with the Centers for Medicare and Medicaid Services (CMS) ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 According ... Transparency Market Research "Regenerative Medicine (Bone and Joint) ... and Tissue Engineering; By Applications - Bone Graft ... Others) - Global Industry Analysis, Size, Share, Growth, ... regenerative medicine (bone and joint) market was valued ...
Breaking Biology Technology:EXpressLO LLC Granted Second U.S. Patent for Innovative Specimen Preparation Methods 2Building 'invisible' materials with light 2WEDI’s HPID Workgroup Announces Release of Issue Brief: “What is the Difference Between a Health Plan and Payer?” 2Regenerative Medicine Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Regenerative Medicine Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Regenerative Medicine Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 4
... Chicago-based Celsis International, a leading global life sciences company, ... process and will de-list from the London Stock Exchange ... "Celsis has a very strong track record of consistent ... results were not being reflected in our share price," ...
... N.J., Oct. 9 Soligenix, Inc. (Soligenix or the ... announced today that Robert J. Rubin, MD, has been ... has had a distinguished career in the healthcare industry ... as president of the national health policy and management ...
... WA, and VANCOUVER, Oct. 9 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, ... Cormack, president and chief executive officer of OncoGenex, has ... The Year(R). The Ernst & Young Entrepreneur Of The ... entrepreneurs that are building successful, dynamic businesses. , "I ...
Cached Biology Technology:Chicago-Based Celsis International Goes Private 2Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 2Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 3Soligenix Appoints Robert J. Rubin, MD, to its Board of Directors 4OncoGenex Pharmaceuticals CEO Named Canada's Pacific Ernst & Young's Entrepreneur Of The Year(R) in the Health Sciences Category 2OncoGenex Pharmaceuticals CEO Named Canada's Pacific Ernst & Young's Entrepreneur Of The Year(R) in the Health Sciences Category 3
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Request Info...
Request Info...
Biology Products: