Navigation Links
Stem cell-based bioartificial tissues and organs
Date:2/18/2013

Surgeon Paolo Macchiarini has made his name by successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material. He now plans to use the technique to recreate more complex tissues, such as the oesophagus and diaphragm or organs such as the heart and lungs. He has also made an experimental attempt to regenerate brain in mice and rats. This is part of the news he will be presenting during his seminar at the scientific AAAS Annual Meeting in Boston.

In June 2011, media all over the world reported about a ground breaking transplant, where a patient received an artificial trachea covered in his own stem cells. The result was an artificial windpipe with biological functions. To date, five operations have been carried out using this technique.

"We learn something from each operation. This means we can develop and refine the technique. We are also evaluating how we can transfer our experiences to other fields, such as neurology. The aim is to make as much use of the body's own healing potential as we can", says Paolo Macchiarini, Professor of Regenerative Surgery at Karolinska Institutet, and responsible for the surgery.

At the AAAS Annual Meeting, he will talk about how he believes the technology can be used in the future. This will include:

  • The plan to operate on a 2 year-old girl in the USA in March. The girl was born without a trachea and has lived her entire life in intensive care, where she breathes through a tube placed in the oesophagus and connected directly to the lungs. Without a new trachea, she will never be able to leave the hospital. This will be the first time the procedure is conducted on a small child. It is also the first time the procedure will be conducted on an individual without a trachea - as previously, diseased organs have been replaced.

  • There are also plans to transplant the oesophagus, an organ that is more complex than a trach
    '/>"/>

Contact: Sabina Bossi
sabina.bossi@ki.se
46-706-146-066
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related biology news :

1. Novel aptamer boosts T cell-based immune response to therapeutic vaccines
2. New technique could make cell-based immune therapies for cancer safer and more effective
3. Discovery of reprogramming signature may help further stem cell-based regenerative medicine research
4. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
5. New methods for quantifying antisense drug delivery to target cells and tissues
6. 3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
7. Long-distance solute transport in trees improved by intercellular pathways in living woody tissues
8. Tiny probes shine brightly to reveal the location of targeted tissues
9. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
10. Why do organisms build tissues they seemingly never use?
11. Penn researchers improve living tissues with 3-D printed vascular networks made from sugar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2015)... DUBLIN , July 07, 2015 ... has announced the addition of the "Biometrics ... and Forecasts 2015-2020" report to their offering. ... a major contributor to this growth and the ... US$5.5 billion in revenue for companies involved in ...
(Date:7/8/2015)... LAKES , N.J. and NEW YORK ... Company) and Guidepoint today announced BD ... start-up healthcare companies with free access to Guidepoint,s expert ... several start-ups that are developing cutting-edge technologies to improve ... a dedicated Guidepoint research manager, each start-up entrepreneur will ...
(Date:7/7/2015)... , July 7, 2015  Based on ... Frost & Sullivan recognizes Credence ID, LLC with ... Entrepreneurial Company of the Year Award. Credence ID ... aid in its mission of offering enrollment and ... globally. As Credence ID was formed by experts ...
Breaking Biology News(10 mins):Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5
... being tested at the National Institute of Standards ... a recent paper,* NIST scientists used surface-enhanced Raman ... optical qualities that make them superior for chemical ... nanoparticles may one day be used in a ...
... the internal head skeleton of Tiktaalik roseae ... step in the evolutionary transition from fish to animals that ... this week,s issue of the journal Nature , show ... changes not only to appendages (fins to limbs) but also ...
... While an international seed bank in a Norwegian island has ... U.S. scientists has just published an article outlining a different ... wild species at intervals in the future effectively ... Bioscience , Steven J. Franks of Fordham University, Susan ...
Cached Biology News:Gold nanostars outshine the competition 2Details of evolutionary transition from fish to land animals revealed 2Scientists propose the creation of a new type of seed bank 2Scientists propose the creation of a new type of seed bank 3
(Date:7/29/2015)... -- Research and Markets ( ... "Global Biosimilars Market, 2015 - 2025" ... Biosimilars Market, 2015 - 2025, report provides an ... With the blockbuster biologics losing patent protection and ... being viewed as viable substitutes to the highly ...
(Date:7/29/2015)... , July 29, 2015  Therapath Neuropathology ... announces increased partnerships with VA and Military Medical ... Nerve Fiber Density (ENFD) and Sweat Gland Nerve ... fiber neuropathy ( https://therapath.com/skin ). ... Fiber Density (ENFD) on punch skin biopsy is ...
(Date:7/29/2015)... Madison, NJ (PRWEB) , ... July 29, 2015 , ... ... and approval of combination products , in particular, drug/device combinations. The current system ... innovation by the Initiative for Patient Centered Innovation (iPCI) of Fairleigh Dickinson ...
(Date:7/29/2015)... Francisco, CA (PRWEB) , ... July 29, 2015 , ... ... in the morning is quite normal. Although there are a considerable number of terms ... well understood that this post-sleep material is a mixture of mucus, blood cells, skin ...
Breaking Biology Technology:Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3Neuropathology services for VA and Military health systems 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 3What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 2What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 3What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 4
... , Point-of-Care Diagnostics Initiative is part of ... & Melinda Gates Foundation and Grand Challenges Canada , ... to create a low-cost portable testing platform for molecular diagnostics ... expected to be completed by 2014, enabling rapid integration of ...
... Corp. Ltd., a developer and marketer of innovative products ... today announced it has entered into a non-exclusive agreement ... RNA extraction products in Sweden and other selected countries ... real-time PCR (qPCR) services and products.  This new agreement ...
... RICHMOND, Calif., May 2, 2012 Sangamo BioSciences, Inc. (Nasdaq: ... accomplishments. For the first quarter ended March 31, ... $0.14 per share, compared to a net loss of $9.6 million, ... of March 31, 2012, the company had cash, cash equivalents and ...
Cached Biology Technology:QIAGEN Joins Grand Challenges in Global Health Initiative to Bring Advanced Point-of-Care Diagnostics to World's Poorest Countries 2QIAGEN Joins Grand Challenges in Global Health Initiative to Bring Advanced Point-of-Care Diagnostics to World's Poorest Countries 3QIAGEN Joins Grand Challenges in Global Health Initiative to Bring Advanced Point-of-Care Diagnostics to World's Poorest Countries 4QIAGEN Joins Grand Challenges in Global Health Initiative to Bring Advanced Point-of-Care Diagnostics to World's Poorest Countries 5ZyGEM Teams With TATAA Biocenter To Distribute Its Innovative Nucleic acid Extraction Kits 2ZyGEM Teams With TATAA Biocenter To Distribute Its Innovative Nucleic acid Extraction Kits 3Sangamo BioSciences Reports First Quarter 2012 Financial Results 2Sangamo BioSciences Reports First Quarter 2012 Financial Results 3Sangamo BioSciences Reports First Quarter 2012 Financial Results 4Sangamo BioSciences Reports First Quarter 2012 Financial Results 5Sangamo BioSciences Reports First Quarter 2012 Financial Results 6Sangamo BioSciences Reports First Quarter 2012 Financial Results 7
... peptide microarrays designed for quantitative assays ... and built on the flexible and ... of customer specified sequences can be ... provide assistance with custom sequence design. ...
... are intended for laboratory research use only. ... neutral buffered formalin and embedded in paraffin. ... by certified pathologists. Tissue cores were ... into a new recipient paraffin block, in ...
... adult normal Mega Western Protein Array was ... Mega Western Protein Arrays are manufactured using ... tissue sources. A protein sample from each ... with a Protein molecular weight marker on ...
... System, Professional Package Superior Protein Detection ... The ProXPRESS 2D Proteomic Imaging System is ... both proteomic and general life science research ... the use of all dyes in the ...
Biology Products: