Navigation Links
Stem cell-based bioartificial tissues and organs
Date:2/18/2013

Surgeon Paolo Macchiarini has made his name by successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material. He now plans to use the technique to recreate more complex tissues, such as the oesophagus and diaphragm or organs such as the heart and lungs. He has also made an experimental attempt to regenerate brain in mice and rats. This is part of the news he will be presenting during his seminar at the scientific AAAS Annual Meeting in Boston.

In June 2011, media all over the world reported about a ground breaking transplant, where a patient received an artificial trachea covered in his own stem cells. The result was an artificial windpipe with biological functions. To date, five operations have been carried out using this technique.

"We learn something from each operation. This means we can develop and refine the technique. We are also evaluating how we can transfer our experiences to other fields, such as neurology. The aim is to make as much use of the body's own healing potential as we can", says Paolo Macchiarini, Professor of Regenerative Surgery at Karolinska Institutet, and responsible for the surgery.

At the AAAS Annual Meeting, he will talk about how he believes the technology can be used in the future. This will include:

  • The plan to operate on a 2 year-old girl in the USA in March. The girl was born without a trachea and has lived her entire life in intensive care, where she breathes through a tube placed in the oesophagus and connected directly to the lungs. Without a new trachea, she will never be able to leave the hospital. This will be the first time the procedure is conducted on a small child. It is also the first time the procedure will be conducted on an individual without a trachea - as previously, diseased organs have been replaced.

  • There are also plans to transplant the oesophagus, an organ that is more complex than a trach
    '/>"/>

Contact: Sabina Bossi
sabina.bossi@ki.se
46-706-146-066
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related biology news :

1. Novel aptamer boosts T cell-based immune response to therapeutic vaccines
2. New technique could make cell-based immune therapies for cancer safer and more effective
3. Discovery of reprogramming signature may help further stem cell-based regenerative medicine research
4. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
5. New methods for quantifying antisense drug delivery to target cells and tissues
6. 3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
7. Long-distance solute transport in trees improved by intercellular pathways in living woody tissues
8. Tiny probes shine brightly to reveal the location of targeted tissues
9. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
10. Why do organisms build tissues they seemingly never use?
11. Penn researchers improve living tissues with 3-D printed vascular networks made from sugar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... YORK , Nov. 18, 2014   ... identity authentication solutions, and MorphoTrust USA ... and services, today announced a strategic partnership to ... enterprise, motor vehicle administration (MVA), airport screening and ... in identity-related solutions, MorphoTrust serves consumers through a ...
(Date:11/10/2014)... began appearing on U.S. store shelves in early 2010, ... since. The small packets can be tossed into a ... liquid or powder. The convenience, though, has come with ... researchers at Nationwide Children,s Hospital found that from 2012 ... 17,230 children younger than 6 years of age swallowing, ...
(Date:11/6/2014)... Fla. -- A groundbreaking paper from a team of ... understanding of how plants could adapt to and survive ... research, published in the latest issue of the journal ... chromatin (the complex of DNA and proteins) is organized ... so that some genes are turned on and others ...
Breaking Biology News(10 mins):EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3Study finds laundry detergent pods, serious poisoning risk for children 2Maize analysis yields whole new world of genetic science 2
... Organisms living on small islands are particularly threatened ... assess these threats. A team of German and British ... of endangered reptiles and amphibians of the Comoro archipelago ... results to point out which species are most threatened ...
... -- Traditionally addressed through hand-weeding and/or herbicide application, controlling ... production. Increased labor costs have made hand-weeding prohibitive as ... may be effective and less expensive, non-target herbicide loss ... the environment. To address the economic and environmental impact ...
... Ariz. -- Associate Professor Paul Blowers of the University ... the 2011 Arizona Professor of the Year, recognized for ... the Advancement of Teaching and the Council for Advancement ... center announced the award on Nov. 17 in Washington, ...
Cached Biology News:Satellite images help species conservation 2Biodegradable mulches successfully control weeds in container-grown arborvitae 2Arizona Engineering associate professor earns national recognition 2
(Date:11/26/2014)... NC (PRWEB) November 26, 2014 PMG ... Advisory Board. PMG Research is a network of sites that ... access to over 2 million patient lives through its partnerships ... is comprised of 11 hub site locations in the Southeastern ... The first term of the board will be ...
(Date:11/26/2014)... (PRWEB) November 25, 2014 Continuing its ... products, earned three prestigious MarCom Awards for outstanding creative ... received a Platinum MarCom Award, the organization’s top honor, ... in St. Louis held in April of this year. ... than 14,000 attendees. Additionally, Nerium was awarded a Gold ...
(Date:11/26/2014)... SoundConnect , an award winning unified ... that Darren Suders has joined the team as Director ... the partner program through innovative offerings, consistent ... Darren brings more than 10-years of channel telecommunication experience ... operations, from policy development, to partner education and to ...
(Date:11/26/2014)... MINNEAPOLIS , Nov. 25, 2014 Bio-Techne ... it has appointed Robert Gavin to serve ... of the Protein Platforms Division.  Mr. Gavin will be ... business segment, which includes the ProteinSimple business acquired in ... San Jose, California -based ProteinSimple ...
Breaking Biology Technology:PMG Research Names Medical Advisory Board 2PMG Research Names Medical Advisory Board 3Nerium International™ Wins One Platinum, Two Gold MarCom Awards 2SoundConnect Appoints Director of Channel Development & Sales 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 3
... Calif., June 2, 2011 Providing a medical explanation for ... scientists from Brazil pursuing a study that started in Dr. ... a new gene regulator called MicroRNA 29 that keeps hearts ... to get to the molecular basis of why exercise is ...
... Tiny electrodes have been coated with a drug-loaded polymer ... detecting a number of neurological symptoms, such as those ... In a study published today, 2 June ... , researchers have developed a novel technology to precisely ...
... Lu, associate professor of materials science and engineering ... recipient of the Friedrich Wilhelm Bessel Research Award ... This award is for scholars, internationally renowned in ... 18 years ago and who are expected to ...
Cached Biology Technology:Scientists Discover Gene Regulator That Helps Hearts Through Exercise 2New technology could inspire brain implant for detecting and treating seizures 2Virginia Tech's Kathy Lu receives Humboldt Foundation research award 2
Umbilical cord blood mononuclear cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood MNCs and T Cells...
Umbilical cord blood basophils, For immunohistochemistry (IHC)...
Umbilical cord blood CD4+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood MNCs and T Cells...
Human endothelial progenitor cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Dendritic Cells and EPCs...
Biology Products: