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Sons of cocaine-using fathers may resist addiction to drug, Penn Medicine study suggests
Date:11/11/2013

xperienced fathers did not cause remodeling of excitatory AMPA receptors, which is thought to be critical for the development of addiction and cocaine craving.

"This adds to the growing body of evidence that cocaine abuse in a father rat can affect how his sons may respond to the drugand point to potential mechanisms that contribute to this phenomenon," said Wimmer. "Further research is needed to better understand how these behavior changes are passed down from one animal generation to the next, and eventually if the same holds true for humans."


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Contact: Steve Graff
stephen.graff@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine
Source:Eurekalert

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