Navigation Links
Sonicating sperm -- the future of male contraception
Date:1/29/2012

The ideal male contraceptive would be inexpensive, reliable, and reversible. It would need to be long acting but have few side effects. New research published in BioMed Central's open access journal Reproductive Biology and Endocrinology used commercially available therapeutic ultrasound equipment to reduce sperm counts of male rats to levels which would result in infertility in humans.

Ultrasound's potential as a male contraceptive was first reported nearly 40 years ago. However the equipment used is now outdated and no longer available. Researchers from the Department of Pediatrics at the University of North Carolina School of Medicine used these experiments as a starting point to see if modern ultrasound equipment usually used for physical therapy could be used as a male contraceptive.

The team led by James Tsuruta found that by rotating high frequency (3MHz) ultrasound around the testes they were able to cause uniform depletion of germ cells throughout the testes. The best results were seen using two sessions consisting of 15 minutes ultrasound, two days apart. Saline was used to provide conduction between the ultrasound transducer and skin, and the testes were warmed to 37 degrees centigrade. Together this reduced sperm to a Sperm Count Index of zero (3 million motile sperm per cauda epididymis).

The World Health Organization has defined oligospermia (low sperm concentration) as less than 15 million sperm per ml. Dr Tsuruta explained, "Unlike humans, rats remain fertile even with extremely low sperm counts. However, our non-invasive ultrasound treatment reduced sperm reserves in rats far below levels normally seen in fertile men (95% of fertile men have more than 39 million sperm in their ejaculate). However further studies are required to determine how long the contraceptive effect lasts and if it is safe to use multiple times."


'/>"/>

Contact: Dr. Hilary Glover
hilary.glover@biomedcentral.com
44-203-192-2370
BioMed Central
Source:Eurekalert

Page: 1

Related biology news :

1. Low sperm count may be associated with prenatal testosterone excess
2. Proteins in sperm unlock understanding of male infertility says new study
3. The more promiscuous the female, the speedier the sperm
4. CSHL scientists discover how companion cells to sperm protect them from genetic damage
5. The egg makes sure that sperm dont get too old
6. Spread your sperm the smart way
7. ESHREs workshop on freezing of human sperm, eggs and embryos in Athens
8. MMS and NOAA scientists study prey of Gulf of Mexico sperm whales
9. Molecular study could push back angiosperm origins
10. Females shut down male-male sperm competition in leafcutter ants
11. UT Southwestern researchers use novel sperm stem-cell technique to produce genetically modified rats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2016)... FRANCISCO and WARSAW, Poland , Nov. 30, 2016 /PRNewswire/ ... It is one of the most crucial aspects of recovery so we need to ... of serious health risks, including heart problems, high blood pressure, stroke, diabetes, and even ... and friends sleep and find a Christmas present that could help them to manage ... ...
(Date:11/28/2016)... Nov. 28, 2016 "The ... of 16.79%" The biometric system market is in ... in the near future. The biometric system market is ... 2022, at a CAGR of 16.79% between 2016 and ... of biometric technology in smartphones, rising use of biometric ...
(Date:11/19/2016)... Securus Technologies, a leading provider of civil and criminal ... monitoring, announced today that it has offered a challenge ... technology judge determine who has the largest and best ... platform, and the best customer service. "ICSolutions ... we do – which clearly is not the case ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... ... December 08, 2016 , ... ... flexible packaging for their exceptionally efficient human mesenchymal stem/stromal cell (hMSC) expansion ... of bioprocess media products engineered to radically streamline culture processes, minimize processing ...
(Date:12/8/2016)... , Dec. 8, 2016 Soligenix, Inc. ... company focused on developing and commercializing products to treat ... announced today that it will be hosting an Investor ... ET on the origins of innate defense regulators (IDRs) ... review of oral mucositis and the recently announced and ...
(Date:12/8/2016)... to fuel Philadelphia,s innovative digital ... Southeastern Pennsylvania (" Ben Franklin "); Independence ... Cross; and Safeguard Scientifics ("Safeguard") (NYSE: SFE ... funding initiative over a four year period to grow ... burgeoning economic vitality in digital health, Ben Franklin ...
(Date:12/7/2016)... ... 07, 2016 , ... Huffman Engineering, Inc. , a ... Certified System Integrator Partner. Huffman Engineering is the only Nebraska-based company recognized ... Integrator Partner certification gives customers confidence that our engineers are fully trained and ...
Breaking Biology Technology: