Navigation Links
Software developed by Boston College lab delivers speed and accuracy to genome research
Date:3/27/2008

CHESTNUT HILL, MA It took a global corps of scientists approximately $500 million and 13 years to identify the more than 35,000 genes of the human genome. Five years later, Boston College Biologist Gabor Marth and his research team have developed software that can analyze half a million DNA sequences in 10 minutes.

The Marth laboratorys proprietary PyroBayes software is one of a new breed of computer programs able to accurately process the mountains of genome data flowing from the latest generation of gene decoding machines, which have placed a premium on computational speed and accuracy in data-crunching fields known as bioinformatics and high-throughput biology, said Marth, an associate professor of Biology.

Were on the edge of a real technological revolution that I think will help us understand the genetic causes of diseases in humans and how genetic materials determine traits in animals, said Marth. It is going to lead to less expensive technologies that will allow researchers to decode any individual.

PyroBayes will aid researchers involved in the 1,000 Genomes Project, which announced last month a plan to sequence the genomes of 1,000 individuals from around the world. The NIH, which helps direct the project, has awarded Marth more than $1.3 million to develop software over the next four years.

The advances of the Marth lab were revealed in two articles published by the professor and his assistants in the February issue of Nature Methods, the premier journal of scientific research methodology.

In an article co-authored by Marth, post-doctoral researcher Chip Stewart, and graduate students Aaron Quinlan and Mike Strmberg, the group unveiled the labs PyroBayes base caller software, which examines data from one of the latest generation of DNA decoding machines from Roche / 454 Life Sciences faster and with far greater accuracy than other programs for pyrosequencing, a technology that utilizes the detection of
'/>"/>

Contact: Ed Hayward
ed.hayward@bc.edu
617-552-4826
Boston College
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Futronic Announces Microsoft Vista and Windows 2008 Server Support for Its Fingerprint Logon Software
2. M2SYS Introduces Revolutionary Biometric Artificial Intelligence Technology to Significantly Reduce Fingerprint Software False Reject Rates
3. LOGICARE Selects M2SYS Biometric Fingerprint Software to Ensure Patient Privacy and Protect Confidential Information
4. Software Techniques Inc. Selects M2SYS Fingerprint Software to Meet Continuous Growth and Demand for Desktop Biometric Time & Attendance Solutions
5. Titanium Group Signs Letter of Intent to Acquire Multimilion Dollar Medical Software Company and Its Existing Sales Network
6. Titanium Group Signs Letter of Intent to Acquire Multimilion Dollar Medical Software Company and Its Existing Sales Network
7. CIC Again Named to Software Magazines Annual Prestigious Software 500 List
8. Aware, Inc. Introduces Biometrics Software for Tenprint Autocapture
9. Radiant Systems Selects BIO-key(R) Biometric Software for POS Solution
10. IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks
11. IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... knowledge regarding Ebola is critical and pertinent for practicing ... global outbreak and epidemic. The Journal, Disaster Medicine ... issue, Ebola Virus and Public Health, to surround the ... this critical societal moment. , On October 17, ... Clinicians . The primer was prepared by Dr. Eric ...
(Date:10/17/2014)... release is available in German . ... a very few drugs. When treating overdoses, doctors are often ... especially difficult if there is a combination of drugs involved. ... and accidentally swallows his grandmother,s pills? ETH professor Jean-Christophe Leroux ... to find an answer to this question. "The task was ...
(Date:10/16/2014)... managers have a new synthesis of recent research findings ... forests in the two states. , The Ecology ... and Washington: A Synthesis of the Relevant Biophysical Science ... report published by the U.S. Forest Service,s Pacific Northwest ... from managers for a synthesis of the large body ...
Breaking Biology News(10 mins):Emergency aid for overdoses 2Emergency aid for overdoses 3New report synthesizes best available science on management of moist mixed-conifer forests 2
... of dinosaur unearthed in Mexico is giving scientists fresh insights ... an international research team led by scientists from the Utah ... To date, the dinosaur record from Mexico has been sparse, ... Natural History, Utahs designated natural history museum. The new ...
... HANOVER, N.H. Dartmouth College researchers and colleagues from ... the beginnings of complex life, i.e. vertebrates, to microRNA. ... regulate gene expression, are behind the origin of early ... to understanding the evolutionary origin of our own lineage, ...
... goal of Raphael Kopan, Ph.D., professor of molecular biology ... The moss plant (Physcomitrella patens) studied in the ... Professor and chair of the WUSTL biology department on ... Heres how. The gene presenilin in mammals ...
Cached Biology News:New dinosaur from Mexico offers insights into ancient life on West America 2New dinosaur from Mexico offers insights into ancient life on West America 3New dinosaur from Mexico offers insights into ancient life on West America 4New dinosaur from Mexico offers insights into ancient life on West America 5New dinosaur from Mexico offers insights into ancient life on West America 6Dartmouth researchers find the root of the evolutionary emergence of vertebrates 2Moss protein plays role in Alzheimer's disease 2Moss protein plays role in Alzheimer's disease 3Moss protein plays role in Alzheimer's disease 4
(Date:10/20/2014)... , Oct. 20, 2014  GenVec, Inc. (NASDAQ: ... P. Horovitz , Ph.D., from its board of directors effective ... in August 2003, and served as its chairman from June ... on the Nominating and Corporate Governance and Audit Committees of ... more than a decade of dedicated service to GenVec, and ...
(Date:10/19/2014)... The Latin American hardware encryption display market report defines ... and forecast of revenue. This market was valued at ... $2,366.8 million by 2018, at a CAGR of 70.3% ... of the Latin American hardware encryption market report to ... also provides a glimpse of the segmentation of the ...
(Date:10/19/2014)... October 19, 2014 The Asia-Pacific Speech ... market in Asia-Pacific with analysis and forecast of revenue. ... in 2014 to $208 million by 2019, at a ... to 2019. , Browse through the TOC of the ... of the in-depth analysis provided. It also provides a ...
(Date:10/18/2014)... October 19, 2014 The “Human ... Acting, Intermediate Acting, Premixed), Modern Human Insulin (Rapid ... Levemir, NovoRapid, Novomix, Tresiba, Others) - Forecast to ... drivers, restraints, challenges, opportunities, current market trends, and ... with the estimates and forecasts of the revenue ...
Breaking Biology Technology:Zola P. Horovitz To Retire From GenVec Board 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 2Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 3Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 5
... US Oncology, Inc . announced that ... counsel, will be departing from the Company, effective November 30, ... had a long and rich history with US Oncology. Beginning ... and consultation as an outside attorney before joining the Company ...
... ST. LOUIS, Nov. 10 At the Board of Directors ... of $.145 per share, an 11.5% increase over the prior ... to shareholders of record on December 1, 2009. , ... Science and High Technology company. Our chemical and biochemical products ...
... Helix Consulting US, a division of London-based Double ... Michael Rizzo to the position of Vice President. ... experienced strategic pricing, reimbursement and market access consultants ... provides product commercialization services to firms in the ...
Cached Biology Technology:US Oncology Announces Retirement of General Counsel Phil Watts 2Double Helix Consulting Enhances its Strategic Product Commercialization Services with Appointment of Michael Rizzo as Vice President 2Double Helix Consulting Enhances its Strategic Product Commercialization Services with Appointment of Michael Rizzo as Vice President 3