Navigation Links
'Snooze button' on biological clocks improves cell adaptability
Date:2/17/2013

The circadian clocks that control and influence dozens of basic biological processes have an unexpected "snooze button" that helps cells adapt to changes in their environment.

A study by Vanderbilt University researchers published online Feb. 17 by the journal Nature provides compelling new evidence that at least some species can alter the way that their biological clocks function by using different "synonyms" that exist in the genetic code.

"This provides organisms with a novel and previously unappreciated mechanism for responding to changes in their environment," said Professor of Biological Sciences Carl Johnson. He and Associate Professor of Biological Sciences Antonis Rokas collaborated on the study.

Like many written languages, the genetic code is filled with synonyms: differently spelled "words" that have the same or very similar meanings. For a long time, biologists thought that these synonyms, called synonymous codons, were in fact interchangeable. Recently, they have realized that this is not the case and that differences in synonymous codon usage have a significant impact on cellular processes, so scientists have advanced a wide variety of ideas about the role that these variations play.

The new insight is not only an important advance in understanding evolution at the molecular level, but it also has potential applications in biotechnology, such as biofuel production, and gene therapy.

"While biological clocks are vital to maintaining healthy patterns of sleep, metabolism, physiology and behavior, under certain environmental conditions strict adherence to these rhythms can be disadvantageous," said Michael Sesma of the National Institute of General Medical Sciences, which partially funded the work. "This work shows how organisms can ignore the clock under certain circumstancesmuch like hitting a biological snooze button on the internal timepieceand enhance their survival in the face of ever-changing circumstances."

The
'/>"/>

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Hitting snooze on the molecular clock: Rabies evolves slower in hibernating bats
2. New guide will allow electric utilities to develop Green Button Web tools
3. Unraveling biological networks
4. New method for estimating parameters may boost biological models
5. A project to research biological and chemical aspects of microalgae to fuel approach
6. EPA to highlight innovative ways to detect and respond to biological threats
7. Salk scientists redraw the blueprint of the bodys biological clock
8. Weeding out invasive species with classical biological control
9. Crime and punishment: The neurobiological roots of modern justice
10. Electric charge disorder: A key to biological order?
11. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... examining only marketing directed at children on the ... found that the majority of black, middle-income and ... tactics. , Authored by Arizona State University researcher ... the first to examine the use of child-directed ... food restaurants and its relationship to demographics. It ...
(Date:11/3/2014)... 2014 Research and Markets has announced ... Technologies, Markets and Companies" to their offering. ... methods, which have already started to play an important role ... replacing the old fashioned bone marrow transplants. Role of cells ... to become a part of medical practice. Stem ...
(Date:11/2/2014)... In this month,s issue of Physics World , ... bridging the "valley of death" to take their innovations ... argues that the gruelling challenge facing all start-up companies ... harder for physicists because of two main factors: physics-based ... and they often turn out to be a lot ...
Breaking Biology News(10 mins):Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3Global Cell Therapy - Technologies, Markets and Companies: 2014 Report 2Global Cell Therapy - Technologies, Markets and Companies: 2014 Report 3The 'valley of death' facing physics start-ups 2
... has to be the niche. As air and water preceded ... stem cells in many tissues and provides factors necessary to ... stem cell dependents. A team of scientists at ... Ph.D., assistant professor in the Laboratory of Genetics, now suggests ...
... experts from across the U.S. and other countries including ... will discuss the latest findings in basic and clinical ... X Conference, to be held July 23-27 in St. ... Fragile X also will be attending the conference., Fragile ...
... in stem cell research help both scientists and regulators ... research funded by the Economic and Social Research Council. ... a balancing act where the autonomy of scientists and ... the need for comparable data. The ambition ...
Cached Biology News:Stem cell chicken and egg debate moves to unlikely arena: the testes 2Stem cell chicken and egg debate moves to unlikely arena: the testes 3Researcher helping to pioneer medical therapy for Fragile X Syndrome presents latest findings 2Standards in stem cell research 2Standards in stem cell research 3
(Date:11/22/2014)... The “Chiral Chromatography Columns Market by type (Empty, ... by Application [GC, LC (HPLC, UHPLC, Flash Chromatography, ... and studies the major market drivers, restraints, opportunities, ... Rest of the World. , Browse 90 market ... pages and in-depth TOC on “Chiral Chromatography Columns ...
(Date:11/22/2014)... , November 21, 2014   ... als Chief Commercial Officer zu KLOX    ... Unternehmensentwicklung und Chief Financial Officer bestellt    ... der Vermarktung seines jüngst zugelassenen Behandlungssystems zur Wundheilung zu ... bzw. das "Unternehmen") ist sehr erfreut, die folgenden personellen ...
(Date:11/21/2014)... The science of light and how it ... than 200 primary students in a traveling program organized ... Otago Physics Department and funded by an SPIE ... the university’s OSA/SPIE Student Chapter visited six primary schools ... from small, rural schools hands-on lessons in optics and ...
(Date:11/21/2014)... Palo Alto, Calif. (PRWEB) November 20, 2014 ... (CHI), a nonprofit, public policy research organization representing ... and pharmaceutical firms, and PwC US ... other states in life sciences industry growth. The ... and 2013. The 2015 California Biomedical Industry ...
Breaking Biology Technology:Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5KLOX Technologies meldet Neubesetzung von Führungspositionen 2KLOX Technologies meldet Neubesetzung von Führungspositionen 3KLOX Technologies meldet Neubesetzung von Führungspositionen 4KLOX Technologies meldet Neubesetzung von Führungspositionen 5Optics and photonics outreach programs share science, spark fascination with light 2Optics and photonics outreach programs share science, spark fascination with light 3California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 2California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 3California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 4
... Madison, Wis. -- Implementation of RFID must be done ... technology offers are to be truly realized, attendees at Friday's ... from Patrick Sweeney, CEO of Virginia-based ODIN Technologies ... address at the lab's open house - an event that ...
... pulling all-nighters, but it happens every year twice, in fact, ... night was no exception. , ,After four months of interviewing ... morning to turn the raw ingredients of the selected companies into ... investors and business development execs who come to the event each ...
... BioSurfaces, Inc., of Madison has been licensed to ... and labeling agents, GenTel announced on Tuesday. , ,GenTel ... reagents of Kreatech Biotechnology BV of Amsterdam, ... The kits are validated for use on GenTel's PATH ...
Cached Biology Technology:RFID expert says piecemeal approach won't work 2RFID expert says piecemeal approach won't work 3RFID expert says piecemeal approach won't work 4DEMOfall - A return to simplicity 2DEMOfall - A return to simplicity 3
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
TXNL2 Antibody...
Mouse monoclonal [3F8 ] to smooth muscle Myosin heavy chain I ( Abpromise for all tested applications). entrezGeneID: 4629 SwissProtID: P35749...
Request Info...
Biology Products: