Navigation Links
'Snooze button' on biological clocks improves cell adaptability
Date:2/17/2013

The circadian clocks that control and influence dozens of basic biological processes have an unexpected "snooze button" that helps cells adapt to changes in their environment.

A study by Vanderbilt University researchers published online Feb. 17 by the journal Nature provides compelling new evidence that at least some species can alter the way that their biological clocks function by using different "synonyms" that exist in the genetic code.

"This provides organisms with a novel and previously unappreciated mechanism for responding to changes in their environment," said Professor of Biological Sciences Carl Johnson. He and Associate Professor of Biological Sciences Antonis Rokas collaborated on the study.

Like many written languages, the genetic code is filled with synonyms: differently spelled "words" that have the same or very similar meanings. For a long time, biologists thought that these synonyms, called synonymous codons, were in fact interchangeable. Recently, they have realized that this is not the case and that differences in synonymous codon usage have a significant impact on cellular processes, so scientists have advanced a wide variety of ideas about the role that these variations play.

The new insight is not only an important advance in understanding evolution at the molecular level, but it also has potential applications in biotechnology, such as biofuel production, and gene therapy.

"While biological clocks are vital to maintaining healthy patterns of sleep, metabolism, physiology and behavior, under certain environmental conditions strict adherence to these rhythms can be disadvantageous," said Michael Sesma of the National Institute of General Medical Sciences, which partially funded the work. "This work shows how organisms can ignore the clock under certain circumstancesmuch like hitting a biological snooze button on the internal timepieceand enhance their survival in the face of ever-changing circumstances."

The
'/>"/>

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Hitting snooze on the molecular clock: Rabies evolves slower in hibernating bats
2. New guide will allow electric utilities to develop Green Button Web tools
3. Unraveling biological networks
4. New method for estimating parameters may boost biological models
5. A project to research biological and chemical aspects of microalgae to fuel approach
6. EPA to highlight innovative ways to detect and respond to biological threats
7. Salk scientists redraw the blueprint of the bodys biological clock
8. Weeding out invasive species with classical biological control
9. Crime and punishment: The neurobiological roots of modern justice
10. Electric charge disorder: A key to biological order?
11. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Va. , Dec. 15, 2014 ... to make it easier to detect and prevent ... Today the agency started performing an ... capability will validate the authenticity of purchased microcircuits ... The new quality control measures will be conducted ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
(Date:12/11/2014)... , Dec. 10, 2014  That blood pressure plays ... a while. Hypertension – the medical term for high blood ... early 1800s, and the inflatable cuff that,s used in measuring ... however, mean there,s nothing new about hypertension, its triggers and ... beliefs about the condition and the best ways to treat ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... fish hatched at Michigan State University has a new look. A ... a number of improvements on the fish, including the ability to ... The fish now has the ability to glide through the water ... that can aid in the cleaning of our lakes and rivers. ...
... NEW YORK January 16, 2013 EcoHealth Alliance, a ... issues, released new research on Ebola virus in fruit bats ... a monthly publication by the Centers for Disease Control and ... in 4% of the 276 bats scientists screened in Bangladesh. ...
... start at the launch pad or even in orbit. They ... instruments that promise to expand our view and understanding of ... lay the groundwork for the Aerosol-Cloud-Ecosystem (ACE) mission, a satellite ... to learn about clouds and aerosols," said ACE science lead ...
Cached Biology News:New robotic fish glides indefinitely 2Recent study suggests bats are reservoir for ebola virus in Bangladesh 2PODEX experiment to reshape future of atmospheric science 2PODEX experiment to reshape future of atmospheric science 3PODEX experiment to reshape future of atmospheric science 4PODEX experiment to reshape future of atmospheric science 5
(Date:12/19/2014)... MA (PRWEB) December 18, 2014 Reports ... in the United States suffer from one or more ... asthma, or cancer. Medication can address some of these ... daily activities that many sufferers face. While implanted nerve ... and stimulate the whole nerve, which can induce side ...
(Date:12/19/2014)... With only 2 weeks left of ... Sartorius Biohit products . The product specials include Buy ... Pipette Trade-in Program, and free pipette tips. , Sartorius ... the world. They are ideal for lab technicians performing ... ,     Full volume range of 0.1 uL to ...
(Date:12/19/2014)... , Dec. 18, 2014 Relmada Therapeutics, Inc. ... the treatment of chronic pain, announced the results of ... "This was a transformational year in Relmada,s history ... for our company," said Sergio Traversa , chief ... have executed on key financial, human resource and clinical ...
(Date:12/17/2014)... 2014 Achim Noack has been named ... Group. In this position, Noack will assist Jerry Stoller, ... develop marketing strategy and supervise global marketing management and ... has tremendous knowledge and experience in the crop protection ... experience and innovative thinking will be a great asset ...
Breaking Biology Technology:Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 2
... , , , , , , , ... 4308 915.021 11/1999 , , , , , , ... Cell line , NIH 3T3, mouse embryo, ... Plasmid pEGFP-N1 (in bidistilled H 2 O), , , ...
... Multiporator / Electroporator 2510 , , , , , , , ... Protocol No. 4308 915.522 03/2002 , , ... , , Microorganism , ... Cell type , Bacteria, gram positive, , ...
... Electroporator 2510 , , , , , , , , ... Protocol No. 4308 915.523 03/2002 , , , , ... , Microorganism , Mycobacterium avium, ... Bacteria, gram positive, , , ...
Cached Biology Technology:NIH 3T3 2Mycobacterium smegmatis 2Mycobacterium avium 2
... new D-LUX Detection Platform combines robust ... the most sensitive, specific, and cost-effective ... D-LUX Detection Platform offers exceptional performance ... TaqMan probes, high signal/background ratio, and ...
Provides continuous mixing action. For use with tubes, vials, and other containers...
... via cardiac puncture from 3 to 4 week ... is then centrifuged and frozen at -70C. The ... at 4C then stored at -70C. DIRECT SALES ... PEL-FREEZ COMPLEMENT, YOU CAN NOW BUY DIRECTLY FROM ...
Modified and insect cell culture tested....
Biology Products: