Navigation Links
Simple model cell is key to understanding cell complexity
Date:5/15/2008

A team of Penn State researchers has developed a simple artificial cell with which to investigate the organization and function of two of the most basic cell components: the cell membrane and the cytoplasm--the gelatinous fluid that surrounds the structures in living cells. The work could lead to the creation of new drugs that take advantage of properties of cell organization to prevent the development of diseases. The team's findings will be published later this month (late May 2008) in the Journal of the American Chemical Society.

"Many scientists are trying to understand cells by turning off genes, one at a time, and are observing the effects on cell function, but we're doing the opposite," said Associate Professor of Chemistry Christine D. Keating, who led the research. "We're starting from scratch, adding in components to find out what is needed to simulate the most basic cell functions. Our goal is to find out how much complexity can be observed in very simple collections of molecules."

Building on previous work that was published in the 16 January 2008 issue of Journal of the American Chemical Society, Keating and her colleagues built a model cell using as the cytoplasm a solution of two different polymers: polyethyleneglycol (PEG) and dextran. The researchers encapsulated this polymer solution inside a cell membrane and, because the two polymers do not mix, one of the phases surrounded the other like the white of an egg around a yolk. The team then exposed the cell to a concentrated solution of sugar. Through a process known as osmosis--in which water diffuses across a cell membrane from a region of higher water concentration to a region of lower water concentration--water traveled from the relatively diluted polymer solution inside the cell to the more concentrated sugar solution outside the cell. As a result, the volume of the polymer solution inside the membrane was reduced.

With a cell membrane that was now
'/>"/>

Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Salt-tolerant gene found in simple plant nothing to sneeze at
2. Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines
3. Simple recipe turns human skin cells into embryonic stem cell-like cells
4. Simple reason helps males evolve more quickly
5. Researchers develop simple method to create natural drug products
6. Gene regulation in humans is closer than expected to simple organisms
7. Safe water: simpler method for analyzing radium in water samples cuts testing time
8. Model successfully predicts large river system fish diversity
9. Climate modelers see modern echo in 30s Dust Bowl
10. A model photochemical compass for bird navigation
11. In computer models and observations, researchers see potential for significant red tide season
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Simple model cell is key to understanding cell complexity
(Date:2/5/2015)... , Jan. 30, 2015  It is gratifying to ... and potential for genomic science as a means to ... prevention and treatment.  I was honored to participate in ... precision medicine program. Since the 1980s ... of genomics—from the first sequenced genome of a free ...
(Date:1/22/2015)... FindBiometrics, the leading source of biometrics industry news, interviews and ... "When we launched FindBiometrics 12 years ago the ... founder and CEO of FindBiometrics. "Now it,s maturing very quickly. ... players on a very broad scale.  We are known for ...
(Date:1/22/2015)... N.C. , Jan. 16, 2015  A man-made form ... memory and other mental capabilities in adults with mild ... pilot study led by researchers at Wake Forest Baptist ... adults diagnosed with amnesic mild cognitive impairment (MCI) or ...
Breaking Biology News(10 mins):J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3
... from the atmosphere are unlikely to offer an economically feasible ... to a report issued by the American Physical Society and ... not kid ourselves that we can pour all the carbon ... it out later at little cost," said Socolow, a professor ...
... scientists have discovered how two closely related proteins guide ... and repelling these axons as they navigate the most ... make remarkably precise connections. The discovery, reported April ... proteins belonging to the "semaphorin" family of guidance cues ...
... of Botany (KIB), part of the Chinese Academy of ... Natural Products and Bioprospecting (NPAB). As a ... in the SpringerOpen portfolio, available on www.springerlink.com . ... Science (CLoS), a collection comprising more than 90 English-language ...
Cached Biology News:Report: Direct removal of carbon dioxide from air likely not viable 2Johns Hopkins scientists reveal nerve cells' navigation system 2Johns Hopkins scientists reveal nerve cells' navigation system 3New SpringerOpen journal from the Chinese Academy of Sciences 2
(Date:3/3/2015)... Md. , March 3, 2015  RegeneRx Biopharmaceuticals, ... editorial in the scientific journal, Expert Opinion on ... his colleague, Dr. Zhenggang Zhang , at the ... reported that Thymosin beta 4 (TB4) has the ... remodeling 24 hours or more post-injury, leading to neurological ...
(Date:3/3/2015)... Kindred Biosciences, Inc. (NASDAQ: KIN ), ... of pets, announced today that it will release its fourth ... after the market close. The Company will host a conference ... Interested parties may access the call by dialing toll-free ... using conference ID 98449349.  The call will ...
(Date:3/3/2015)... Mar. 03, 2015 Research and Markets ... of Jain PharmaBiotech,s new report "Personalized Medicine ... offering. , The aim of ... the right drug to the right patient and, ... treatment for a patient according to his/her genotype. ...
(Date:3/3/2015)... , March 3, 2015 ... with tools for implementing competency-based training to comply with ... DirectCourse is offering a new crosswalk tool ... (HCBS) implement competency-based training for direct service workers as ... & Medicaid Services (CMS) regulations. CMS amended ...
Breaking Biology Technology:Researchers at Henry Ford Hospital Propose Thymosin Beta 4 as Novel Way to Treat Neural Injury and Neurodegenerative Diseases 2Researchers at Henry Ford Hospital Propose Thymosin Beta 4 as Novel Way to Treat Neural Injury and Neurodegenerative Diseases 3Global Personalized Medicine Market Report 2015 - Scientific and Commercial Aspects 2014-2024 2Global Personalized Medicine Market Report 2015 - Scientific and Commercial Aspects 2014-2024 3Elsevier's DirectCourse Can Help States Meet and Exceed New CMS Requirements for Home and Community-Based Services 2Elsevier's DirectCourse Can Help States Meet and Exceed New CMS Requirements for Home and Community-Based Services 3
... Aug. 10, 2011 Genesis Biopharma, Inc. (OTC/BB: ... today announced it has signed a Cooperative Research ... Institute (NCI).  Under the terms of the five-year ... work with Steven A. Rosenberg, M.D., Ph.D., the ...
... Accuray Incorporated (Nasdaq: ARAY ), the premier ... to present at the Wedbush Life Sciences: Management Access Conference ... a.m. ET/6:10 a.m. PT. A live webcast of ... page of the Company,s Web site at http://www.accuray.com . ...
... YORK, Aug. 9, 2011 Reportlinker.com ... report is available in its catalogue: ... Market: Facilities, Test Volumes, and Sales ... http://www.reportlinker.com/p0591318/Global-Microbiology-Testing-Market-Facilities-Test-Volumes-and-Sales-Forecasts-by-Country.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=In_Vitro_Diagnostic This ...
Cached Biology Technology:Genesis Biopharma Signs Cooperative Research and Development Agreement With the National Cancer Institute to Develop Cancer Immunotherapies 2Genesis Biopharma Signs Cooperative Research and Development Agreement With the National Cancer Institute to Develop Cancer Immunotherapies 3Global Microbiology Testing Market: Facilities, Test Volumes, and Sales Forecasts by Country 2
... peptide derived from the internal region of ... Specific for the internal region of the ... the target band at ~590 kDa. ... media from primary tracheobranchial epithelial cultures and ...
Lipid-rich bovine serum albumin for cell culture. It is chromatographically purified and has an IgG content 1.0% (w/w)....
Prepared with distilled water. Yeast extract solution is autolyzed at 150 g/L....
Request Info...
Biology Products: