Navigation Links
Shedding light on cancer cells
Date:9/24/2009

Scientists label cells with coloured or glowing chemicals to observe how basic cellular activities differ between healthy and cancerous cells. Existing techniques for labelling cells are either too slow or too toxic to perform on live cells. Now, a study reviewed by Philip Dawson, a member of Faculty of 1000 Biology and leading authority in chemistry and cell biology, describes a novel labelling technique that uses a chemical reaction to make live cancer cells light up quickly and safely.

Researchers at Massachusetts General Hospital developed a two-step process to specifically tag cancer cells. First, chemically modified antibodies home in on cancer cells. Then a chemical reaction called cycloaddition transfers a dye onto the antibody making the cancer cells glow when viewed through a microscope.

The novel cycloaddition reaction is fast, very specific, and requires minimal manipulation of the cells. Dawson comments that, in combining antibody binding with the cycloaddition, "low signal-to-noise ratios are achieved". This new labelling technique could be used to track the location and activity of anti-cancer drugs, the location of cancer-specific proteins within the cell, or to visualize cancer cells inside a living organism.

Dawson concludes that cycloaddition will allow scientists to observe live cancer cells in the body, leading to a better understanding of cancer's basic processes.


'/>"/>

Contact: Steve Pogonowski
press@f1000.com
Faculty of 1000: Biology and Medicine
Source:Eurekalert

Page: 1

Related biology news :

1. Clemson scientists shed light on molecules in living cells
2. September Geology and GSA Today media highlights
3. Highlights from the September 2007 Journal of the American Dietetic Association
4. Genome study shines light on genetic link to height
5. Pig study sheds new light on the colonisation of Europe by early farmers
6. Researchers developing device to predict proper light exposure for human health
7. AGU journal highlights -- Sept. 6, 2007
8. IDEMA Reveals Program Highlights for DISKCON USA 2007
9. Men shed light on the mystery of human longevity, study finds
10. Zebrafish to shed light on human mitochondrial diseases
11. UT researcher sheds new light on hybrid animals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... fragmentation of forests in the Amazon help create ... to rapid and widespread forest loss during drought ... findings show that forests in the Amazon could ... with forest fires lead to large-scale loss of ... assistant professor of geography, Penn State. , "We ...
(Date:4/17/2014)... in the Cell Press journal Current Biology ... rather novel sex lives. The Brazilian insects, which represent ... Neotrogla , are the first example of an animal ... been identified in several different animals, Neotrogla ... is also reversed," says Kazunori Yoshizawa from Hokkaido University ...
(Date:4/17/2014)... animals and plant life, but there,s an invisible machine ... the soil, decomposing organic matter and releasing carbon into ... play in ecological systems, their identities have only now ... a genetic map of more than 10,000 species of ... week in the Proceedings of the National Academy ...
Breaking Biology News(10 mins):Drought and fire in the Amazon lead to sharp increases in forest tree mortality 2Drought and fire in the Amazon lead to sharp increases in forest tree mortality 3In sex-reversed cave insects, females have the penises 2Stanford biologists help solve fungal mysteries 2Stanford biologists help solve fungal mysteries 3
... found that the allergenicity of peanut products could be ... North Carolina A&T University report their findings today at ... Microbiology. , "Due to the wide use of peanuts ... soups there is a need to inactivate peanut allergens ...
... Researchers from the University of Pittsburgh report the first ... treatment of congenital muscular dystrophy (CMD) in mice, demonstrating ... on gene therapy ever being feasible for children with ... in this week's online edition of the Proceedings of ...
... analyze DNA from giant, extinct lemurs, according to a Yale ... the National Academy of Sciences. , Radiocarbon dating of the ... that each of the individuals analyzed died well over 1,000 ... professor in the Department of Ecology and Evolutionary Biology. , ...
Cached Biology News:No small feat: First ever gene therapy success for muscular dystrophy achieved 2No small feat: First ever gene therapy success for muscular dystrophy achieved 3Ancient DNA confirms single origin of Malagasy primates 2
(Date:1/15/2014)... AudioNotch is the internet's leading provider ... treatment of tinnitus. Patients listen to sound therapy that ... period of weeks to months, their tinnitus volume decreases. , ... Notched Music and Notched White Noise. Now, AudioNotch is pleased ...
(Date:1/14/2014)... January 14, 2014 Date: Friday, April 11, ... Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... organization solely dedicated to finding a cure for hepatitis B ... will host its annual Crystal Ball on Friday, April 11 ...
(Date:1/14/2014)... San Diego, CA (PRWEB) January 14, 2014 ... based on the products of cells grown under simulated ... an international license agreement with Suneva Medical, Inc. for ... media (CCM). , This agreement is an ...
(Date:1/14/2014)... Calif. , Jan. 14, 2014 As pet owners drew ... doubt many of them wrote: "Take better care of my furry ... even designer clothes and top-brand carrying cases to take the little ... parents might also feel compelled to buy some pricey toys at ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2
... 10% of all sales ... to be donated to ALSF, ... Tastykake snack line, today announced the re-issue,of Alex,s Lemon Krimpets(R) and ... nation,s leading organizations in the,fight against childhood cancer. Named for Alexandra ...
... 4, 2008 Scientists in fields,as diverse as ... the Olympus FluoroPoint(TM) single molecule fluorescence,detection system for ... laboratories around the world, the system, with its ... use, is now,available for the first time to ...
... Professionals and Addressing the ... Issues Facing Clinical Labs Worldwide, ABBOTT PARK, Ill., April ... support of an initiative to,raise international awareness of the role ... contribution to improve,patient outcomes. Through a program called Labs Are ...
Cached Biology Technology:Tasty Baking Company Continues Partnership With Alex's Lemonade Stand Foundation To Fight Childhood Cancer 2Olympus FluoroPoint(TM) System Provides High-Sensitivity Single Molecule and Protein Interaction Analysis for Screening and Research 2Olympus FluoroPoint(TM) System Provides High-Sensitivity Single Molecule and Protein Interaction Analysis for Screening and Research 3International Federation of Clinical Chemistry Forms Partnership With the Labs Are Vital(TM) Initiative 2International Federation of Clinical Chemistry Forms Partnership With the Labs Are Vital(TM) Initiative 3
MarrowMAX Bone Marrow Medium...
... recognizes murine IRF7 protein, and ... related IRF proteins. Reactivity of ... protein was confirmed by western ... cells transfected with IRF7. Reactivity ...
Rabbit anti-phospho-EGFr (Tyr992) - Concentrate...
Contains L-glutamine...
Biology Products: