Navigation Links
Sex on the brain: 'Doublesex' gene key to determining fruit fly gender
Date:3/21/2010

orks the wiring for sexual behaviour."

fru has so far been found only in insects; dsx, however, is found throughout the animal kingdom, where it plays a fundamental role in sex determination, and so is of particular interest to researchers.

Using a transgenic tool generated in his lab, Dr Goodwin and colleagues were able to map dsx throughout the fly's development using a fluorescent protein marker that illuminates areas where DSX is active. This highlighted profound differences in neural architecture between the sexes. In males, the researchers were able to show that dsx complements fru activity to create a 'shared' male-specific neural circuit; in females (where fru is inactive), dsx forms a female-specific circuit.

Importantly the researchers were able to manipulate these cells, impinging their ability to function, and show that these circuits are responsible for behaviours unique to the individual sexes.

"It has been suggested that there are only minor trivial differences between the neural circuits that underlie behaviour in males and females," explains Dr Goodwin. "We have shown that in fact there is quite a bit of difference in the number of neurons and how these neurons connect, or 'talk', to each other. These differences can have big consequences on the structure and function of the nervous system."

In addition, while dsx was known to establish the gender of the adult fly, the pattern of dsx activity in the adult was unknown. Dr Goodwin and colleagues have shown that this pattern is not ubiquitous, but rather is restricted in a specific and telling manner.

Some tissues, such as blood cells, may not require a defined gender in order to function. However, others such as the 'fat body', which in the adult fly functions in part to produce hormones, and the oenocytes, which produce sex-specific pheromones, require a specified sexual identity. It was unsurprising to Dr Goodwin and colleagues to find dsx e
'/>"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Nanowire biocompatibility in the brain: So far so good
2. ChemoBrain: How cancer therapies can affect your mind
3. The human brain: Detective of auditory and visual change
4. Columbia geneticists uncover new gene involved in determining hair texture and density in humans
5. Early environment may be key to determining bird migration location
6. New study shows teens who drink 100 percent fruit juice have more nutritious diets overall
7. Caltech researchers obtain first brain recordings from behaving fruit flies
8. Online programs improve fruit and vegetable consumption
9. The how and why of freezing the common fruit fly
10. From fruit fly wings to heart failure -- why Not(ch)?
11. Caltech scientists find emotion-like behaviors, regulated by dopamine, in fruit flies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... its newborn screening program into a model other states can ... first-ever Newborn Screening Quality Award from the March of Dimes. ... Arizona,s Department of Health Services director, with the award at ... of full transparency for the length of time it takes ... for analysis, and set a target of having 95 percent ...
(Date:9/18/2014)... disciplines will be celebrated tonight at the third annual ... the health of premature infants and in paving the ... whose work was supported by the National Science Foundation, ... Energy Commission, will be honored at a ceremony at ... group of Members of Congress will be on hand ...
(Date:9/18/2014)... 2014 Elsevier, a world-leading provider of scientific, ... the Australasian Research Management Society (ARMS), recognized the ... the 5th Scopus Young Researcher of the Year ... at the National Convention Centre and in conjunction ... by guests representing Australia,s and New Zealand,s scientific ...
Breaking Biology News(10 mins):March of Dimes honors Arizona with first-ever newborn screening award 2March of Dimes honors Arizona with first-ever newborn screening award 33rd annual Golden Goose award ceremony honors 8 researchers; Unusual work had big results 2Elsevier and Australasian Research Management Society award scientists at Scopus ceremony 2
... and Women,s Hospital (BWH) announces the launch of the ... division within the Department of Medicine. The Channing Division ... biology-driven approach to define the causes of complex diseases. ... develop new ways to classify and treat those diseases. ...
... of Health have developed a new silk-based stabilizer that, ... up to temperatures of 140 degrees Fahrenheit. ... to keep some vaccines and antibiotics refrigerated, which could ... to third world populations. Vaccines and antibiotics often ...
... When coronary blood vessels are constricted, cardiologists try to ... grid-like implants called stents, which stabilize the veins and ... obliteration. A lesser known fact is that stents can ... This kind of respiratory stenosis, which may be caused ...
Cached Biology News:BWH launches a new research division focused on integrating systems biology and medicine 2Vaccine and antibiotics stabilized so refrigeration is not needed -- NIH study 2Vaccine and antibiotics stabilized so refrigeration is not needed -- NIH study 3Non-slip tracheal implants 2
(Date:9/20/2014)... MediVet America and NanoFiber Veterinary ... at the specialized Wolvega Horse Clinic. , Due to ... was ruptured 90% and her deep digital flexor tendon ... sentence for a horse. , The clinic has performed ... This revolutionary regenerative option for ruptured tendons has ...
(Date:9/19/2014)... light, rather than electricity, to move data would ... is a growing concern as chips, transistor counts ... optical circuits light emitters, modulators, and detectors ... promising light source for optical chips is molybdenum ... deposited as a single, atom-thick layer. Other experimental ...
(Date:9/19/2014)... , Sept. 19, 2014  Nektar Therapeutics ... from preclinical studies characterizing the analgesic profiles of ... kappa opioid receptor agonist molecules. The preclinical research ... medicinal chemistry platform. The analgesic properties ... the medical literature. 1,2 Kappa opioid receptors ...
(Date:9/19/2014)... Minnesota (PRWEB) September 19, 2014 ... related food industries will gather October 5–8, 2014, ... the Rhode Island Convention Center in Providence, Rhode ... feature the work of food scientists, chemists, microbiologists, ... control, and food production management. To date, 1,000 ...
Breaking Biology Technology:World’s first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction 2World’s first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction 3Toward optical chips 2Toward optical chips 3Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 2Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 3Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 4Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 5Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3
... of technologies showcased at the American Society for, Therapeutic Radiology and ... ... 2008, BOSTON, Sept. 22 ASTRO Booth # 547 -- Varian,Medical ... cancer and other disorders, is showcasing a full,spectrum of technologies and products ...
... Delivery Enable CyberKnife Centers ... Increasing Demand for Radiosurgery, SUNNYVALE, Calif., Sept. 22 ... in the field of radiosurgery,announced today that Oklahoma CyberKnife ... dramatically reduced treatment,planning and delivery times over the last ...
... from Varian Medical Systems and BrainLAB enabling, non-invasive treatment of ... ... system, PALO ALTO, Calif., and WESTCHESTER, Ill., Sept. ... of stereotactic body radiosurgery (SBRT) for the treatment,of cancer and other conditions. ...
Cached Biology Technology:Varian Medical Systems Exhibits a New Version of RapidArc(TM) Radiotherapy Technology and Other Products for Fast, Precise Cancer Treatment 2Varian Medical Systems Exhibits a New Version of RapidArc(TM) Radiotherapy Technology and Other Products for Fast, Precise Cancer Treatment 3Varian Medical Systems Exhibits a New Version of RapidArc(TM) Radiotherapy Technology and Other Products for Fast, Precise Cancer Treatment 4Oklahoma CyberKnife Center Cuts Treatment Time in Half With Next Generation CyberKnife Technology 2Oklahoma CyberKnife Center Cuts Treatment Time in Half With Next Generation CyberKnife Technology 3Oklahoma CyberKnife Center Cuts Treatment Time in Half With Next Generation CyberKnife Technology 4Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 2Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 3Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 4Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 5
Active GST Protein...
... Cyno Serum • Cyno serum is collected off ... and 5-7 years of age. Available Anticoagulants: ... (Na) N-06: K2EDTA N-08: Potassium ... Alsevers N-05: ACD N-07: CPD ...
All serum is collected from adult animals aged 6 months or older. Certified U.S. orgin. Pricing: $35/unit for 1 - 10 units...
adult...
Biology Products: