Navigation Links
Sex on the brain: 'Doublesex' gene key to determining fruit fly gender
Date:3/21/2010

The brains of males and females, and how they use them, may be far more different then previously thought, at least in the fruit fly Drosophila melanogaster, according to research funded by the Wellcome Trust.

In a paper published today in the journal Nature Neuroscience, researchers from the University of Glasgow and the University of Oxford, have shown that the gene known as 'doublesex' (dsx), which determines the shape and structure of the male and female body in the fruit fly, also sculpts the architecture of their brain and nervous system, resulting in sex-specific behaviours.

The courtship behaviour of the fruit fly has long been used to study the relationship between genes and behaviour: it is innate, manifesting in a series of stereotypical behaviours largely performed by the male. The male chases an initially unreceptive female, and 'woos' her through tapping and licking and using wing vibration to generate a 'courtship' song. If successful, the female will slow and present a receptive posture, which allows copulation to occur.

For some time now, the gene 'fruitless' (fru), which is specific to the adult male fruit fly, was thought to be the key to male behaviour and the development of male specific neural circuitry of flies.

However, the researchers have shown that fru does not explain the complete repertoire of male behaviours in the fly: female flies in which the fru gene has been activated demonstrate some, but not all, of the characteristics usually associated with courtship behaviour in males. The researchers have also shown that dsx plays an important role in shaping the neural circuitry involved in this behaviour.

"The dogma was that dsx made fruit flies look the way they did and fru made them behave the way they did," explains Dr Stephen Goodwin from the University of Oxford, who led the research. "We now know that this is not true. dsx and fru act together to form the neuronal netw
'/>"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Nanowire biocompatibility in the brain: So far so good
2. ChemoBrain: How cancer therapies can affect your mind
3. The human brain: Detective of auditory and visual change
4. Columbia geneticists uncover new gene involved in determining hair texture and density in humans
5. Early environment may be key to determining bird migration location
6. New study shows teens who drink 100 percent fruit juice have more nutritious diets overall
7. Caltech researchers obtain first brain recordings from behaving fruit flies
8. Online programs improve fruit and vegetable consumption
9. The how and why of freezing the common fruit fly
10. From fruit fly wings to heart failure -- why Not(ch)?
11. Caltech scientists find emotion-like behaviors, regulated by dopamine, in fruit flies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... nocturnal animals, bats are perfectly adapted to a life without ... the reflected echoes to measure distance to obstacles or prey. ... echo delays. A study carried out by researchers at Technische ... this map dynamically adapts to external factors. , ... flies in too close to an object, the number of ...
(Date:8/31/2014)... a fast and accurate tool to diagnose tuberculosis ... newly developed test (TAM-TB assay) is the first ... children. The test features excellent specificity, a similar ... of a blood test. The promising findings are ... in children, particularly in tuberculosis-endemic regions. , The ...
(Date:8/31/2014)... not busy attacking us, germs go after each other. ... disaster for the infected microbes: Sometimes viruses actually carry ... expand its diet or better attack its own hosts. ... immune system would robotically destroy anything it recognized as ... have now revealed that one variety of the bacterial ...
Breaking Biology News(10 mins):Zooming in for a safe flight 2New tuberculosis blood test in children is reliable and highly specific 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 2Discovery reveals how bacteria distinguish harmful vs. helpful viruses 3
... A genetic variant of a receptor in the ... whether the neurotransmitter dopamine is released in the brain ... researchers at the National Institute on Alcohol Abuse and ... Dopamine is involved in transmitting the euphoria and ...
... first time successfully imaged the internal tissues of a ... technique borrowed from biomedical science. The findings are published ... worms are important for the functioning of marine ecosystems, ... understand their physiology, ecology and evolution," explained John Dinley ...
... imbalances at the heart of childhood brain tumors known as ... active in some tumors and is now the focus of ... research, published in the May 17 online edition of the ... between the defects underlying these tumors in children and adults, ...
Cached Biology News:Receptor variant influences dopamine response to alcohol 2Scientists use biomedical technique to image marine worm 2Push to understand basis of childhood brain tumors leads to a new treatment target 2Push to understand basis of childhood brain tumors leads to a new treatment target 3
(Date:9/2/2014)... 2, 2014  Spherix Incorporated (SPEX) -- an intellectual property development ... property, today announced that the United States Patent & ... in the month of August that are part of ... The issued patents are: , U.S.RE45,065 ... 19, 2014; and , U.S.RE45,095 issued August 26, ...
(Date:9/1/2014)... 1, 2014 Reportlinker.com announces that a ... catalogue: India Solid Waste Management Vehicles ... http://www.reportlinker.com/p02350445/India-Solid-Waste-Management-Vehicles-Market-Forecast-and-Opportunities-2019.html In ... governing bodies responsible for complete handling and regulation ... average, around 135,000 MT solid waste is generated ...
(Date:8/31/2014)... 2014 Wockhardt Limited today announces a major ... research when two of its drugs, WCK 771 and ... (QIDP) status from U.S. Food & Drug Administration (FDA). ... pathogens which have a high degree of unmet need ... Disease Control (a top U.S. government health and safety ...
(Date:8/31/2014)... 31, 2014 This is a ... of the Epoxy Hardener industry in Global ... of the industry, including definitions, applications and industry ... market analysis are provided with a focus on ... market. A comparison between the international and Chinese ...
Breaking Biology Technology:United States Patent & Trademark Office Issues Three New Standard Essential Patents to Spherix 2India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 2India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 3India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 4India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 5India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 6India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 7India Solid Waste Management Vehicles Market Forecast and Opportunities, 2019 8U.S. FDA Grants QIDP Status for Wockhardt Anti-Infective Drug Discovery Program 2U.S. FDA Grants QIDP Status for Wockhardt Anti-Infective Drug Discovery Program 3Epoxy Hardener Industry Development Trends in Global & China Regions Now Available at ReportsnReports.com 2Epoxy Hardener Industry Development Trends in Global & China Regions Now Available at ReportsnReports.com 3
... , , , , , , ... The time increment, which can be programmed as desired with every temperature , ... temperature for each cycle. , , With ... successive extension of the , elongation. , ...
... for Detecting Listeria monocytogenes , , ... Andrea Tanzer and Christian Rohrer , Andrea Tanzer, Institute ... Christian Rohrer, Eppendorf AG, Germany, , , ... Bacterial enteritides, which are triggered by contaminated foodstuffs, , ...
... , , , , ... Dietmar Kahle, PhD , Peter Scheinert, PhD, Bernhard-Nocht-Institute ... Hamburg , former address: University of Kiel, Institute ... , Barbara Behrens, PhD, and Dietmar Kahle, PhD, Eppendorf-Netheler-Hinz ...
Cached Biology Technology:Two-dimensional Optimization of a Semi-nested PCR, for Detecting Listeria monocytogenes 2Two-dimensional Optimization of a Semi-nested PCR, for Detecting Listeria monocytogenes 3Two-dimensional Optimization of a Semi-nested PCR, for Detecting Listeria monocytogenes 4Two-dimensional Optimization of a Semi-nested PCR, for Detecting Listeria monocytogenes 5Two-dimensional Optimization of a Semi-nested PCR, for Detecting Listeria monocytogenes 6Two-dimensional Optimization of a Semi-nested PCR, for Detecting Listeria monocytogenes 7Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 2Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 3Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 4Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 5Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 6Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 7Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 8Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 9Optimizing DNA Amplification Protocols using the Eppendorf Mastercycler 10
The FliTrx Panning Kit is designed to simplify panning for protein-protein interactions with the FliTrx Random Peptide Display Library or the pFliTrx Peptide Display Vector....
... The GeneSwitch Cell Lines stably express ... Each cell line is functionally tested ... with the expression control vector pGene/V5-His/lacZ ... after treatment with mifepristone (Figure 1). ...
... Modules Highly efficient ... cloning into advanced λ ... For flexibility ... Systems, the modules of ...
... Re-Blot Western Blot Recycling Kit is ... Western blots that have been developed ... other isotopes. It is not recommended ... 4-chloronapthol, etc.), as it is not ...
Biology Products: