Navigation Links
Scientists tackle mystery mountain illness
Date:8/21/2007

Experts at the University are studying an illness known as HAPE (high altitude pulmonary oedema), which causes fluid to build up in the lungs can and can occur from as low as 2,500 metres, affecting people of all age groups and fitness levels.

Little is known about the condition and there is no way of predicting who is likely to be affected although studies have suggested a genetic link. It is thought that around one in 50 people who travel to high altitudes suffer from HAPE.

The database, which is being run in collaboration with researchers from America, Austria, Bolivia, and Britain, aims to encourage registration from previous sufferers of HAPE. It will facilitate research that could potentially identify people susceptible to the condition. Genetic studies using the database may also provide greater understanding of what happens in HAPE sufferers' lungs.

Dr Kenneth Baillie, co-ordinator of the database and a researcher at the University of Edinburgh, said: There is no way of predicting who is likely to suffer from HAPE, as it can affect anyone even if you are young, healthy and active. Because it occurs from 2,500 metres, it can affect skiers as well as mountaineers. Treatment options are very limited and sufferers need to descend from high altitude and see a doctor straight away.

A major problem is that sufferers may not know that they have HAPE until it is too late. Once the symptoms start to appear which may include breathlessness at rest and blueness of the lips sufferers may not realise the severity of the illness and the urgency of reducing altitude and seeking medical treatment. It may also be that sufferers are not in a position to go down a mountain in time, whether this is due to how ill they are, weather conditions or how high up they are. This all reinforces how important it is to find out who may be susceptible in advance so that they can either try to prevent the onset of the illness or not put themselves in a potentially life-threatening situation.

Use of the database will be open to researchers worldwide, although details of individual members will be not be given out without their consent.

HAPE is the most common form of altitude sickness and can kill within hours if untreated. As the illness progresses, it can cause drowsiness and lack of coordination, leading to a coma and death. As cases are not registered, nobody knows exactly how many people have died as a result of the condition.

The main treatment is descent, but this is often impossible as a sufferer may need to be carried for miles on a stretcher, only to descend a few hundred feet. Other treatments include breathing oxygen and two drugs, dexamethasone and nifepidine, which may not be available when somebody becomes ill.

Blood vessels inside the lungs constrict in response to low oxygen to such an extent that fluid is forced from the capillaries (narrow tubes through which blood cells pass), leading to flooding of the lungs air sacs.

Risk factors include rapid ascent, physical exertion and a previous history of the condition. By understanding who is most at risk, potential sufferers could take precautions such as climbing much more slowly or taking drugs to prevent the onset of the condition.


'/>"/>
Contact: Tara Womersley
tara.womersley@ed.ac.uk
44-131-650-9836
University of Edinburgh
Source:Eurekalert

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
3. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
4. UAB scientists discover the origin of a mysterious physical force
5. Fox Chase Cancer Center scientists identify immune-system mutation
6. Scientists Replicate Hepatitis C Virus in Laboratory
7. Scientists detect probable genetic cause of some Parkinsons disease cases
8. Scientists find missing enzyme for tuberculosis iron scavenging pathway
9. Scientists seek answers on what activates deadly anthrax spores
10. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
11. Scientists collaborate to assess health of global environment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. ... company, announces the filing of its 2016 Annual Report on Form ... Exchange Commission. ... Form 10-K is available in the Investor Relations section of the ... on the SEC,s website at http://www.sec.gov . 2016 ...
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... San Diego-based team building and cooking events ... announced today. The bold new look is part of a transformation to increase ... a significant growth period. , It will also expand its service offering from its ...
(Date:10/10/2017)... ... October 10, 2017 , ... For the ... won a US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled to ... Experience from US2020. , US2020’s mission is to change the trajectory of STEM ...
(Date:10/10/2017)... -- International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... market and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase ... "The residential security market has experienced continued growth, ...
(Date:10/10/2017)... SANTA BARBARA, CALIFORNIA (PRWEB) , ... October 10, ... ... risk management, technological innovation and business process optimization firm for the life sciences ... the BoxWorks conference in San Francisco. , The presentation, “Automating GxP ...
Breaking Biology Technology: