Navigation Links
Scientists reproduce evolutionary changes by manipulating embryonic development of mice
Date:7/30/2014

A group of researchers from the University of Helsinki and the Universitat Autnoma de Barcelona have been able experimentally to reproduce in mice morphological changes which have taken millions of years to occur. Through small and gradual modifications in the embryonic development of mice teeth, induced in the laboratory, scientists have obtained teeth which morphologically are very similar to those observed in the fossil registry of rodent species which separated from mice millions of years ago.

To modify the development of their teeth, the team from the Institute of Biotechnology of the University of Helsinki worked with embryonic teeth cultures from mice not coded by the ectodysplasin A (EDA) protein, which regulates the formation of structures and differentiation of organs in the embryo throughout its development. The teeth obtained with these cultures which present this mutation develop into very basic forms, with very uniform crowns. Scientists gradually added different amounts of the EDA protein to the embryonic cells and let them develop.

The researchers observed that the teeth formed with different degrees of complexity in their crown. The more primitive changes observed coincide with those which took place in animals of the Triassic period, some two hundred million years ago. The development of more posterior patterns coincides with the different stages of evolution found in rodents which became extinct already in the Palaeocene Epoch, some 60 million years ago. Researchers have thus achieved experimentally to reproduce the transitions observed in the fossil registry of mammal teeth.

The team of scientists were able to contrast the shape of these teeth with a computer-generated prediction model created by Isaac Salazar-Ciudad, researcher at the UAB and at the University of Helsinki, which reproduces how the tooth changes from a group of equal cells to a complex three-dimensional structure, with the full shape of a molar
'/>"/>

Contact: Isaac Salazar-Ciudad
Isaac.salazar@uab.cat
34-935-812-730
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. Queens scientists seek vaccine for Pseudomonas infection
3. Scientists produce eye structures from human blood-derived stem cells
4. American Society of Plant Biologists honors early career women scientists
5. Brandeis scientists win prestigious prize for circadian rhythms research
6. Scientists discover new method of proton transfer
7. Salk scientists open new window into how cancers override cellular growth controls
8. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
9. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
10. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
11. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... June 30, 2015 To bolster its efforts and ... Corp. announced today the addition of two new team members. ... board advisor and David Raviv will act as ... HYPR Corp.,s commitment to providing the most secure solutions for ... co-founded Layer 7 Technologies, a provider of security and ...
(Date:6/30/2015)... June 30, 2015 Genisphere announced ... CEO to help further develop Genisphere,s therapeutics capabilities and ... experience, having spent much of the last 25 years ... Baxter Bioscience, and Johnson & Johnson. Tom started his ... and Biotech Corporate Finance. He graduated from Dartmouth College ...
(Date:6/29/2015)... June 24, 2015 Research ... the "Latin America Biomedical Sensors Market - Growth, ... The Latin America Biomedical Sensors market is ... of 2.04% over the period 2014-2020 The ... to the genetic formulation of each individual. These sensors ...
Breaking Biology News(10 mins):HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3Latin America Biomedical Sensors Market Report 2015-2020 2
... JISC Collections has purchased the archive content of ... protocols. With immediate effect the SpringerProtocols archive content ... of charge to UK Higher and Further Education ... than 31,000 protocols, most of which come from ...
... , May 2, 2013 CDX Diagnostics, Inc ... ), filed a patent infringement action against Histologics, LLC, ... Pathology, LLP d/b/a Avero Diagnostics (collectively, "Defendants") in the ... New York . According to court ...
... New discoveries of the way plants transport important substances ... pests, increase salt and drought tolerance, control water loss ... the supply of food and energy for our rapidly ... 12 leading plant biologists from around the world whose ...
Cached Biology News:JISC Collections purchases SpringerProtocols 2Shared Medical Resources, LLC files suit against Histologics, LLC, Women's Health Laboratories and Avero Diagnostics for Willful Patent Infringement 2New plant protein discoveries could ease global food and fuel demands 2New plant protein discoveries could ease global food and fuel demands 3New plant protein discoveries could ease global food and fuel demands 4
(Date:7/1/2015)... Bermuda , July 1, 2015  Axovant ... company focused on the treatment of dementia, today ... briefing on July 22 at 5:45 p.m. EDT ... the Alzheimer,s Association International Conference 2015 (AAIC). ... remarks: , Dr. Lawrence Friedhoff ...
(Date:7/1/2015)... ... July 01, 2015 , ... Apex Therapeutics announced today that ... in Philadelphia, PA. , The presentation took place on Tuesday, June 16 ... for the development of APX3330 for the treatment of pancreatic cancer. A copy ...
(Date:6/30/2015)... ... 30, 2015 , ... Students and faculty from Beijing City ... of “Integrative Biotechnology,” an applied biotechnology course team-taught by faculty members from both ... students from both universities and is taught on both continents. , “Our alliance ...
(Date:6/30/2015)... June 30, 2015  Juniper Pharmaceuticals, Inc. (Nasdaq: ... developing therapeutics that address unmet medical needs in ... Elston will present at the Cantor Fitzgerald ... 8, 2015Time: , 4:45 PM EDTLocation: , Le ... archive): , www.juniperpharma.com, under  ,Investor, or  ...
Breaking Biology Technology:Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3Apex Therapeutics Presented Company Overview at This Year’s BIO International Convention in Philadelphia, PA 2Rivier University and Beijing City University Academic and Cultural Exchanges Begin 2Juniper Pharmaceuticals to Present at Cantor Fitzgerald Inaugural Healthcare Conference on July 8, 2015 2
... (NYSE AMEX: IBIO) announced today the pricing of an ... for gross proceeds of approximately $10 million.  Each unit consists ... warrant to purchase one share of common stock.  The warrants ... be exercisable beginning one year and one day from the ...
... 10, 2012 Northwest Biotherapeutics (OTC.BB: NWBO) (NW Bio) today ... 10:45 am (PST) in the Windsor Room of the Sir ... SF 2012 Conference for emerging biotech companies held over 3 ... Conference.  Over one thousand attendees are expected to be listening ...
... $650,000 awarded to Innovative Libraries, New Scholars and Nurse Faculty ... the 2011 grant recipients for the Innovative Libraries in Developing ... been committed to nine institutions around the world in addition ...  The Elsevier Foundation is funded by Elsevier , a ...
Cached Biology Technology:iBio, Inc. Prices $10 Million Public Offering 2iBio, Inc. Prices $10 Million Public Offering 3iBio, Inc. Prices $10 Million Public Offering 4NW Bio to Present Today at the OneMedForum SF 2012 Conference 2NW Bio to Present Today at the OneMedForum SF 2012 Conference 3Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 2Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 3Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 4Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 5Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 6Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 7Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 8Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 9Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries 10
... emerging as a powerful new tool for ... only amino groups have been able to ... as our Sulfo-SBED. Sulfhydryl-reactive Mts-Atf-Biotin and its ... to the protein interaction tool chest that ...
... a compact benchtop and stackable multi-function ... with a large display screen to ... Air circulation inside to evenly distribute ... be easily calibrated from the microprocessor ...
... Nonanoyl-N-methylglucamide White solid. ... be readily removed by dialysis. Useful ... ≥98% by HPLC. Absorbance (10%, ... 2 O. CMC 19 - 25 ...
...
Biology Products: