Navigation Links
Scientists have discovered genes that increase the risk of osteoporosis and fractures
Date:4/23/2012

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have identified the genetic variations that are believed to cause osteoporosis. The study, published in Nature Genetics and involving leading researchers from Sweden and the world, shows among other interesting facts that women with a higher proportion of genetic variations associated with osteoporosis have a more than 50 percent increased fracture risk.

Osteoporosis is a common and a devastating age-related disease about 50 percent of all who have a hip fracture after age 80 die within one year from the time of injury. The consequences of osteoporosis are therefore well-known, but the causes of the disease are largely unknown.

56 genetic regions for bone density

In a groundbreaking international study, which is led partially from the Sahlgrenska Academy, researchers have now succeeded in identifying a total of 56 genetic regions that control bone density in human beings. Fourteen of these genetic variants increase the risk of fractures, the study, which has been published in the world-leading journal Nature Genetics, has shown.

"This is the first time anyone has identified the genetic variants that are so strongly associated with an increased risk of fracture," comments Claes Ohlsson, a professor at the Sahlgrenska Academy.

Study on 80,000 people

An international consortium, which also involves researchers from Ume University, Uppsala University and Malm University, is behind the study. In total, the researchers studied the genetic make-up of a total of 80,000 people and 30,000 fracture cases, making it the world's largest genetic study in this particular area of research.

"We can prove that women who have a large number of genetic variants associated with low bone density have up to a 56 percent higher risk of osteoporosis as compared with women who have a normal set-ups of the same genetic variants," com
'/>"/>

Contact: Claes Ohlsson
claes.ohlsson@medic.gu.se
University of Gothenburg
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Marine scientists urge government to reassess oil spill response
2. Scientists find Achilles heel in life-threatening malaria parasites
3. Scientists find that neurological changes can happen due to social status
4. Scientists discover switch in plants to create flowers
5. Merkin Family Foundation to fund next generation of Broad Institute scientists
6. Scripps Research Institute scientists develop antidote for cocaine overdose
7. Scientists trace evolutionary history of what mammals eat
8. Scientists find neural stem cell regulator
9. Scientists identify FLT3 gene as a valid therapeutic target in acute myeloid leukemia
10. Scientists complete first-ever emperor penguin count from space
11. Scientists count penguins from space
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists have discovered genes that increase the risk of osteoporosis and fractures
(Date:11/4/2014)... 2014 – University of Utah engineers developed the first ... fuel produce electricity without needing to ignite the fuel. ... portable electronics, off-grid power and sensors. , A study ... American Chemical Society journal ACS Catalysis . , ... reaction between a fuel and an oxygen-rich source such ...
(Date:11/4/2014)... --   3D scanner developer ... Fuel3D , a developer of 3D scanning solutions, today ... million (£4 million). This funding builds on the company,s initial ... paves the way for the commercial launch of the company,s ... was led by Chimera Partners and will be used to ...
(Date:11/3/2014)... , Nov. 3, 2014  NeuroSigma ® , ... life sciences company focused on commercialization of its ... for the treatment of neurological and neuropsychiatric disorders, ... Property has issued a Notice of Allowance for ... is co-owned by NeuroSigma and the Regents of ...
Breaking Biology News(10 mins):Jet-fueled electricity at room temperature 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 2NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 3
... exhaust particles from traffic pollution leads to increased asthma ... this is due to increased blood levels of IL-17A, ... children with high diesel exposure. , The study by ... online in the Journal of Allergy and Clinical ...
... with the impact of climate change, archaeologists suggest we spare ... the last ice age. "The period scientists call the ... significant climatic event ever faced by humans on this continent," ... said. Research recently published in the Journal ...
... gobble up a baby placed in her arms, even ... everyone has noticed or felt, could have biological underpinnings ... international team of researchers has found evidence of this ... olfactory -- thus non-verbal and non-visual -- chemical signals ...
Cached Biology News:Climate change nothing new in Oz 2Why do you want to eat the baby? 2
(Date:11/18/2014)... BRUNO, Calif. , Nov. 18, 2014 ... a platinum sponsor of the 10th Annual World Stem Cell ... regenerative medicine stakeholders. The 2014 World Stem Cell Summit will ... San Antonio, Texas . The ... discovery and development of lifesaving cures and therapies, convening the ...
(Date:11/18/2014)... Orleans, LA (PRWEB) November 17, 2014 ... of build-to-order, open architecture blade-based and rackmount computing ... NVIDIA® Tesla® K80 dual-GPU accelerator throughout its GPU-enabled ... a pair of the company’s latest proprietary 80-lane ... to eight discrete NVIDIA Tesla K80 dual-GPU accelerator ...
(Date:11/18/2014)... 17, 2014 Athena Signature Series: Turning Cancer ... Beverly Emerson, a professor in the Regulatory Biology Laboratory at ... recent discovery points to an “off switch” for drug resistance ... how her local research is making a global impact in ... and then join host Cheryl K. Goodman, CEO of Social ...
(Date:11/18/2014)... November 18, 2014 American Process ... recently formed a partnership with researchers at Georgia ... of Technology, and the USDA’s Forest Products Laboratory ... with nanocellulose. Nanocellulose is a rapidly emerging high ... the project is to replace heavy steel structures ...
Breaking Biology Technology:Cord Blood Registry Sponsors 2014 World Stem Cell Summit 2Cord Blood Registry Sponsors 2014 World Stem Cell Summit 3Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 2Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 3American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 2American Process Inc. Announces Partnership to Develop Ultra-Strong, Lightweight Automotive Components Using Nanotechnology from Nature 3
... 18, 2011 Palatin Technologies, Inc. (NYSE Amex: ... February 24, 2011 at 11:00 a.m. Eastern Time to discuss ... for its programs under development.   Schedule ... Q2 Fiscal Year 2011 Conference Call-Live Domestic Dial-In ...
... to sharpen images of celestial bodies can now help scientists ... of a mouse. Eric Betzig, a group leader at the ... his team,s latest work using adaptive optics for biology at ... of Science in Washington, D.C. during a press conference on ...
... (Nasdaq: CDXS ) today announced that Byron Dorgan, ... the company,s Board of Directors. Senator Dorgan retired from the ... U.S. Congress.   (Photo:   http://photos.prnewswire.com/prnh/20110217/SF50619 ) ... our Board," said Alan Shaw, Ph.D., President and Chief Executive ...
Cached Biology Technology:Improving microscopy by following the astronomers' guide star 2Improving microscopy by following the astronomers' guide star 3Improving microscopy by following the astronomers' guide star 4Former Senator Byron Dorgan Elected to Codexis Board 2
Applications: Immunohistochemistry, ISH, FISH, CISH....
... fit into the Universal Test ... to greatly increase your microplate ... plates at an angle, and ... shaker at once for quick ...
Mixing speed from 750-3200RPM, small vortexing orbit of1.0mm...
Autoclavable, variable volumefitted w./ an anti-drip safety valve; borosilicate glass barrelprotected with transparentpolypropylene sleeve; spring-lock cursor design ensuresfine adjustment for exact ...
Biology Products: