Navigation Links
Scientists have discovered genes that increase the risk of osteoporosis and fractures
Date:4/23/2012

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have identified the genetic variations that are believed to cause osteoporosis. The study, published in Nature Genetics and involving leading researchers from Sweden and the world, shows among other interesting facts that women with a higher proportion of genetic variations associated with osteoporosis have a more than 50 percent increased fracture risk.

Osteoporosis is a common and a devastating age-related disease about 50 percent of all who have a hip fracture after age 80 die within one year from the time of injury. The consequences of osteoporosis are therefore well-known, but the causes of the disease are largely unknown.

56 genetic regions for bone density

In a groundbreaking international study, which is led partially from the Sahlgrenska Academy, researchers have now succeeded in identifying a total of 56 genetic regions that control bone density in human beings. Fourteen of these genetic variants increase the risk of fractures, the study, which has been published in the world-leading journal Nature Genetics, has shown.

"This is the first time anyone has identified the genetic variants that are so strongly associated with an increased risk of fracture," comments Claes Ohlsson, a professor at the Sahlgrenska Academy.

Study on 80,000 people

An international consortium, which also involves researchers from Ume University, Uppsala University and Malm University, is behind the study. In total, the researchers studied the genetic make-up of a total of 80,000 people and 30,000 fracture cases, making it the world's largest genetic study in this particular area of research.

"We can prove that women who have a large number of genetic variants associated with low bone density have up to a 56 percent higher risk of osteoporosis as compared with women who have a normal set-ups of the same genetic variants," com
'/>"/>

Contact: Claes Ohlsson
claes.ohlsson@medic.gu.se
University of Gothenburg
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Marine scientists urge government to reassess oil spill response
2. Scientists find Achilles heel in life-threatening malaria parasites
3. Scientists find that neurological changes can happen due to social status
4. Scientists discover switch in plants to create flowers
5. Merkin Family Foundation to fund next generation of Broad Institute scientists
6. Scripps Research Institute scientists develop antidote for cocaine overdose
7. Scientists trace evolutionary history of what mammals eat
8. Scientists find neural stem cell regulator
9. Scientists identify FLT3 gene as a valid therapeutic target in acute myeloid leukemia
10. Scientists complete first-ever emperor penguin count from space
11. Scientists count penguins from space
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists have discovered genes that increase the risk of osteoporosis and fractures
(Date:10/16/2014)... Institute of Marine Science have received a 3-year, ... identify the streams and wetlands most vulnerable to ... local governments and citizens conserve these important ecosystems. ... of tidal-marsh observations first gathered by VIMS scientists ... can today,s researchers accurately map the slow but ...
(Date:10/16/2014)... respiratory tract infections and worldwide claims the lives ... and Ghent University have succeeded in developing a ... infection. , Xavier Saelens (VIB/UGent): "We discovered ... for the development of a novel approach to ... in numerous small children and elderly people." , ...
(Date:10/15/2014)... assess the pandemic risk from strains of influenza virus ... allow ourselves to become complacent that the most substantial ... scientists. , Influenza pandemics arise when a new virus ... widespread immunity – spreads in the human population. There ... years, the worst of which – the 1918 Spanish ...
Breaking Biology News(10 mins):EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3New perspectives for development of an RSV vaccine 2Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2
... A large collaborative study has added to the ... a person will be. The research, published by Cell ... of Human Genetics , identifies uncommon and previously unknown ... the genetic architecture of other complex traits. Although ...
... Most agricultural crops require large quantities of ... for growers is finding ways to balance the ... potentially harmful nitrates that can leach into ground ... "low-input" approaches is challenging researchers to identify genotypes ...
... traditionally relied heavily on hand thinning, a necessary but ... costs and a limited workforce, peach and other stone ... string thinners to minimize the need for hand thinning. ... when it was evaluated in four U.S. growing regions; ...
Cached Biology News:Large-scale analysis identifies new genetic alterations associated with height 2Improving nitrogen use efficiency lessens environmental impact 2Hybrid string blossom thinner tested in peach orchards 2
(Date:10/20/2014)... , Oct. 20, 2014 PureTech , ... tackling big healthcare problems, announced today the closing ... with participation from Invesco Perpetual, a $120 Billion ... to drive PureTech,s existing pipeline forward and to ... has the scientific creativity to really go for ...
(Date:10/20/2014)... 20, 2014 Local veterinary surgeon, Dr. ... investigational study of donor stem cells for dogs with ... therapy and has performed clinical stem cell therapy for ... to determine if a single injection of donor stem ... help reduce pain and inflammation in the treated joints. ...
(Date:10/19/2014)... 19, 2014 NextCODE Health, which enables clinicians and ... real time, today announced the launch of its new genomic ... at the American Society of Human Genetics (ASHG) annual meeting ... sign up and apply for free beta access, visit ... benefits can be viewed here . The ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 The Asia-Pacific ... Analytics market in Asia-Pacific with analysis and forecast of ... million in 2014 to $208 million by 2019, at ... 2014 to 2019. , Browse through the TOC of ... idea of the in-depth analysis provided. It also provides ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
... Calif., March 1, 2011 MAP Pharmaceuticals, Inc. (Nasdaq: ... year ended December 31, 2010. The net loss for ... to $13.4 million during the same period in 2009. The net ... compared to $9.0 million for the year ended December 31, 2009. ...
... NBS ), an international biopharmaceutical company with operations ... Smith, the Company,s Chairman and CEO, will present on Tuesday, ... Annual Analyst Conference. The Conference will be held at the ... York. Dr. Smith will present as part of Track 2: ...
... 2011 /PRNewswire-Asia-FirstCall/ -- ShengdaTech, Inc. ("ShengdaTech" or the "Company") ... nano-precipitated calcium carbonate ("NPCC") in China, today announced that ... Anhui Guo, COO and acting CFO and Mr. A. ... & Renshaw Annual China Investment Conference to be held ...
Cached Biology Technology:MAP Pharmaceuticals Reports 2010 Fourth Quarter and Year End Financial Results 2MAP Pharmaceuticals Reports 2010 Fourth Quarter and Year End Financial Results 3MAP Pharmaceuticals Reports 2010 Fourth Quarter and Year End Financial Results 4MAP Pharmaceuticals Reports 2010 Fourth Quarter and Year End Financial Results 5MAP Pharmaceuticals Reports 2010 Fourth Quarter and Year End Financial Results 6MAP Pharmaceuticals Reports 2010 Fourth Quarter and Year End Financial Results 7NeoStem to Present at Wall Street Forum 2011 Financial Conference on Tuesday, March 1 2NeoStem to Present at Wall Street Forum 2011 Financial Conference on Tuesday, March 1 3NeoStem to Present at Wall Street Forum 2011 Financial Conference on Tuesday, March 1 4ShengdaTech to Present at Rodman & Renshaw Annual China Investment Conference in Shanghai 2
Reactivity: Human...
... EasyComp Transformation Kit is designed for ... cells. Advantages over commonly used transformation ... LiCl methods include:- Cells can be made ... - Competent cell preparation and transformation solutions ...
...
... Enhancer System is used in ... optimize PCR of problematic and/or ... Enhancer Solution with 10X PCRX ... specificity broader magnesium concentration broader ...
Biology Products: