Navigation Links
Scientists find bone-marrow environment that helps produce infection-fighting T and B cells
Date:2/24/2013

DALLAS Feb. 24, 2013 The Children's Medical Center Research Institute at UT Southwestern has deepened the understanding of the environment within bone marrow that nurtures stem cells, this time identifying the biological setting for specialized blood-forming cells that produce the infection-fighting white blood cells known as T cells and B cells.

The research found that cells called early lymphoid progenitors, which are responsible for producing T cells and B cells, thrive in an environment known as an osteoblastic niche. The investigation, published online today in Nature and led by Dr. Sean Morrison, also establishes a promising approach for scientists to map the entire blood-forming system.

Scientists already know how to manufacture large quantities of stem cells that give rise to the nervous system, skin, and other tissues. But they have been unable to make blood-forming stem cells in a laboratory, in part because of a lack of understanding about the niche in which blood-forming stem cells and other progenitor cells reside in the body.

"We believe this research moves us one step closer toward the development of cell therapies in the blood-forming system that don't exist today," said Dr. Morrison, Director of the Institute and Professor of Pediatrics at UT Southwestern Medical Center. "In understanding the environments for blood-forming stem cells and those of different kinds of progenitor cells, we can work toward reproducing those environments in the lab and growing cells that can be transplanted to treat a host of medical conditions."

These findings eventually may help increase the safety and effectiveness of bone-marrow transplants, such as those needed after healthy marrow is destroy
'/>"/>

Contact: Jeff Carlton
jeffrey.carlton@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. Queens scientists seek vaccine for Pseudomonas infection
3. Scientists produce eye structures from human blood-derived stem cells
4. American Society of Plant Biologists honors early career women scientists
5. Brandeis scientists win prestigious prize for circadian rhythms research
6. Scientists discover new method of proton transfer
7. Salk scientists open new window into how cancers override cellular growth controls
8. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
9. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
10. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
11. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists find bone-marrow environment that helps produce infection-fighting T and B cells
(Date:5/6/2015)... Israel , May 6, 2015 LifeBEAM, ... most established helmet producer, announced today that they will ... Helmet, the world,s first bio-sensing cycling helmet and the ... released in two new colors in order to give ... the product. In addition, LifeBEAM and Lazer announced their ...
(Date:4/27/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces that its ... the first week of May, 2015 and will be ... Gino Pereira , Chief Executive ... company as Wocket® enters the consumer market. We would ...
(Date:4/20/2015)... Calif. , April 20, 2015 Huntington ... Gabriel Valley to implant a new miniaturized, wireless monitoring ... System is the first and only FDA-approved heart failure ... hospital admissions when used by physicians to manage heart ... sensor that is implanted in the pulmonary artery (PA) ...
Breaking Biology News(10 mins):LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3
... 2011A compact, self-contained, automated system for surveillance and screening ... infectious diseases is a step closer to reality, thanks ... University of California Los Angeles School of Public Health, ... LANL and the UCLA School of Public Health will ...
... New Haven, Conn. Triceratops and Torosaurus have ... a new discovery traces the giants, family tree further back ... reigned long before its more well-known descendants, making it the ... species, called Titanoceratops after the Greek myth of ...
... is available in French and German . ... of public attention. In particular silver nanoparticles are being investigated ... regulatory authorities. The assumption behind this interest is that they ... Bernd Nowack and Harald Krug, together with Murray Heights of ...
Cached Biology News:LANL to certify automated influenza surveillance system 2LANL to certify automated influenza surveillance system 3Newly discovered dinosaur likely father of Triceratops 2Nanosilver: A new name -- well-known effects 2Nanosilver: A new name -- well-known effects 3
(Date:5/27/2015)... MARLBOROUGH, Mass. , May 27, 2015 /PRNewswire/ ... a biotechnology company focused on discovering and developing ... and ophthalmology, today announced that it has commenced a ... warrants to purchase shares of its common stock ... its common stock. The shares of common stock, ...
(Date:5/27/2015)... , May 27, 2015 /CNW/ - CQDM, Brain Canada ... to $8.5M to six (6) multi-disciplinary and multi-provincial research ... within their Focus on Brain strategic initiative. To this ... involved as in-kind contributions. This exciting announcement was made ... for Neuroscience in the presence of Inez Jabalpurwala, President ...
(Date:5/27/2015)... BETHESDA, Md. , May 27, 2015  Northwest ... biotechnology company developing DCVax® personalized immune therapies for cancer, ... Chief Technical Officer of the Company, will be making ... Annual Meeting in Chicago on ... CDT, at the Industry Expert Theater in McCormick Place. ...
(Date:5/27/2015)... 27, 2015 The Medical Innovation Impact ... of regulation on medical innovation, has been developed at ... of Fairleigh Dickinson University’s ( FDU ) Rothman Institute ... pertains to new FDA (Food & Drug Administration) ... the approval of certain medical devices. , “The ...
Breaking Biology Technology:RXi Pharmaceuticals Announces Proposed Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces Proposed Public Offering of Common Stock and Warrants 3Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 2Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 3Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 4Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 5Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 6Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 7Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 8Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 9Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 10NW Bio To Present Overview Of DCVax-Direct Phase I Trial In Chicago This Weekend 2NW Bio To Present Overview Of DCVax-Direct Phase I Trial In Chicago This Weekend 3Medical Innovation Impact Index Launched at Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) under the Rothman Institute 2
... All amounts are in U.S. dollars, QUEBEC CITY, Aug. ... AEZ), a global biopharmaceutical company focused on,endocrinology and oncology, today ... 30, 2008., Second Quarter 2008 Highlights, - ... - First efficacy trial: patient enrollment completed; ...
... Shipments up More than 35% Compared to the previous Quarter ... Production Reaches 200,000 OmniPods per Month, BEDFORD, ... leader in patch pump technology with its OmniPod(R),Insulin Management System, ... ended June 30, 2008., Second quarter 2008 reported revenue ...
... Aug. 12 Biopharmaceutical manufacturers,responsible for an ... monoclonal antibodies, and vaccines -- are faced ... type of product being assessed. A,new whitepaper ... and testing requirements associated with the aseptic ...
Cached Biology Technology:AEterna Zentaris Reports Second Quarter 2008 Financial and Operating Results 2AEterna Zentaris Reports Second Quarter 2008 Financial and Operating Results 3AEterna Zentaris Reports Second Quarter 2008 Financial and Operating Results 4AEterna Zentaris Reports Second Quarter 2008 Financial and Operating Results 5AEterna Zentaris Reports Second Quarter 2008 Financial and Operating Results 6AEterna Zentaris Reports Second Quarter 2008 Financial and Operating Results 7Insulet Reports Second Quarter 2008 Results 2Insulet Reports Second Quarter 2008 Results 3Insulet Reports Second Quarter 2008 Results 4Insulet Reports Second Quarter 2008 Results 5Insulet Reports Second Quarter 2008 Results 6Insulet Reports Second Quarter 2008 Results 7Insulet Reports Second Quarter 2008 Results 8White Paper Explains Aspects of Testing From Purified Bulk Drug Substance to Sterile Liquid Final Drug Product 2
Rabbit polyclonal to Yaf9 ( Abpromise for all tested applications)....
... Bovine Calf Serum; U.S. sourced, ... an uncompromising quality; Low hemoglobin; ... from animals of US origin; ... who seek an uncompromising quality. ...
...
NEWBORN CALF SERUM AND PLASMA...
Biology Products: