Navigation Links
Scientists film inner workings of the immune system
Date:12/3/2008

Forget what's number one at the box office this week. The most exciting new film features the intricate workings of the body, filmed by scientists using ground-breaking technology.

For the first time in Australia, scientists at Sydney's Centenary Institute have filmed an immune cell becoming infected by a parasite and followed the infection as it begins to spread throughout the body.

Professor Wolfgang Weninger, head of the Immune Imaging program at the Centenary Institute, says the discovery (published in PLoS Pathogens) was made possible using high powered multi-photon microscopy which allows real cells to be viewed in real time.

"Using multi-photon microscopy, we studied dendritic cells in the skin. Under normal conditions we found the cells in the epidermis (top layer) were static, whereas in the dermis (second layer) they were very active, moving around as though seeking out pathogens," explains Professor Weninger. "Once we established this, it was fascinating to introduce the Leishmania infection and watch as the parasite was picked up by the cells and the process by which it began to spread throughout the body."

Leishmaniasis affects up to 12 million people in parts of Africa, the Middle East and South America. The disease causes skin sores and can affect internal organs such as the spleen, liver and bone marrow. If left untreated, it can be fatal.

The ability to visually follow a pathogen on its journey through the immune cells provides critical insight for future vaccine design and has potential to improve current vaccinations.

"We now have a general idea of how pathogens are recognised by the immune system and which cells are involved," Professor Weninger says. "This means we can look at identifying the molecules responsible for the uptake of Leishmania infection and these molecules could become vaccine targets. Additionally, we can investigate the immune responses of other infections
'/>"/>

Contact: Erin Sharp
e.sharp@centenary.org.au
61-295-656-118
Research Australia
Source:Eurekalert

Page: 1 2

Related biology news :

1. Rooted plants move mysteriously down greenways, scientists say
2. Caltech scientists show function of helical band in heart
3. Argonne scientists discover possible mechanism for creating handedness in biological molecules
4. Scientists developing food allergy treatment
5. Wistar scientists find key to keeping killer T cells in prime shape for fighting infection, cancer
6. CSHL scientists discover a new way in which epigenetic information is inherited
7. Caltech scientists develop barcode chip for cheap, fast blood tests
8. UNC scientists teach enzyme to make synthetic heparin in more varieties
9. Childrens Hospital scientists achieve repair of injured heart muscle in lab tests of stem cells
10. Scientists shed light on evolution of gene regulation
11. Scientists build roach motel for nasty bugs of the bacterial variety
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... nature, the right amount of death at the right ... according to new research that could help in understanding ... stocks. , In a paper in the journal ... researcher and European colleagues conclude that the kind of ... loss of individuals, or mortality, depends on the size ...
(Date:11/4/2014)... marketing directed at children on the interior and ... the majority of black, middle-income and rural communities ... Authored by Arizona State University researcher Punam Ohri-Vachaspati ... to examine the use of child-directed marketing on ... and its relationship to demographics. It adds to ...
(Date:11/4/2014)... , Nov. 4, 2014   Neurotechnology ... today announced that the latest version of its ... the Ongoing MINEX evaluation organized by ... fingerprint algorithms using the INCITS 378 fingerprint standard ... requirement in public tenders in the ...
Breaking Biology News(10 mins):When less is more: Death in moderation boosts population density in nature 2Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3
... on a tree trunk always points north. According to new ... also provide a new "compass" for stem cell research, telling ... Dr. Nir Ohad of Tel Aviv University,s ... University of Freiburg have discovered a new use for the ...
... the sea but the medaka knows what it likes. A new ... shows how a single gene mutation that turns Japanese Killifish a ... members of the opposite sex. The medaka, ... range of colours; from brown, to more uncommon orange and grey ...
... of family medicine at SUNY Downstate Medical Center in Brooklyn, ... European Association for the Study of Diabetes (EASD) on October ... October 2 in Vienna, Austria. Dr. Feinman will ... Dietary Strategies in the Treatment of Diabetes. According ...
Cached Biology News:Telltale moss 2Fish go mad for ginger gene 2
(Date:11/27/2014)... , Nov. 27, 2014 ... the "Global Palmitic Acid Industry Report 2014" ... The Global Palmitic Acid Industry ... the current state of the global palmitic acid industry. ... the industry including definitions, classifications, applications and industry chain ...
(Date:11/27/2014)... -- First articles published now available ... Elsevier , a world-leading provider of scientific, technical and ... the launch of a new journal: Extreme ... launch of Extreme Mechanics Letters is driven ... applied sciences such as micro and nanotechnologies, biotechnologies, soft ...
(Date:11/27/2014)... BELLINGHAM, Washington, and PITTSFIELD, Massachusetts, USA (PRWEB) November 26, ... pinpoint cancer cells with more accuracy, additive systems to ... improve highway safety by analyzing road conditions are among ... Awards for Photonics Innovation . The awards are sponsored ... photonics , and Photonics Media . , Winners ...
(Date:11/26/2014)... The report on the Global Smart Sensor Market ... for revenue forecasts and market trends. It expects the ... 2013 to 2018. At the projected rate, the market ... by 2018. , Browse through the Global Smart Sensor ... the market segmentation and in-depth analysis supported by a ...
Breaking Biology Technology:Global Palmitic Acid Industry Report 2014 2Elsevier Announces the Launch of a New Journal: Extreme Mechanics Letters 2Elsevier Announces the Launch of a New Journal: Extreme Mechanics Letters 3Finalists Named for 2015 Prism Awards for Photonics Innovation 2Finalists Named for 2015 Prism Awards for Photonics Innovation 3Finalists Named for 2015 Prism Awards for Photonics Innovation 4Finalists Named for 2015 Prism Awards for Photonics Innovation 5Global Smart Sensor Market in Building Automation is expected to reach a value of $1,415.6 million by 2018 - Report by MicroMarket Monitor 2Global Smart Sensor Market in Building Automation is expected to reach a value of $1,415.6 million by 2018 - Report by MicroMarket Monitor 3Global Smart Sensor Market in Building Automation is expected to reach a value of $1,415.6 million by 2018 - Report by MicroMarket Monitor 4
... Radio frequency identification technology is often touted as a way ... world, the technology is bringing other, perhaps more important benefits: ... supply chain now, and there are tremendous applications in health ... the marketplace," said Reik Read, an analyst with Robert ...
... Madison, Wis. Wisconsin's research and development funding has exceeded expectations, reaching ... had set a target of $3.3 billion by 2005. , ... R&D spending per capita, and 13 th in academic R&D ... match the growth rate in R&D the last few years," said ...
... - TEKLYNX International a developer of ... (AIDC) marketplace, has announced LABELVIEW 8 label design and ... code label printing. , ,The updates enhance label ... greatly extend Pocket LABELVIEW printer support to over 1,000 ...
Cached Biology Technology:RFID can be a matter of life and death in the medical world 2RFID can be a matter of life and death in the medical world 3RFID can be a matter of life and death in the medical world 4RFID can be a matter of life and death in the medical world 5New report says Wisconsin R&D spending exceeding expectations 2
Goat polyclonal to Lipocalin 2...
Immunogen for A300-655A was a phosphorylated synthetic peptide, which represented a portion of human RNA Polymerase II (GeneID 5430) around serine 5 of the C-terminal repeat YSPTSPS....
Acetylcholinesterase from human and monkey....
Excellent safety and durability., Remote control can be easily operated in your hand., Constant voltage control with 2 sets of terminals., Precise and durable circuit design. ...
Biology Products: