Navigation Links
Scientists discover the mechanism of heart failure in fish exposed to oil spills
Date:2/14/2014

ith each heartbeat, countless cardiac muscle cells are synchronized so that their individual contractions add up to the coordinated pumping action of the heart. Near the end of each contraction cycle, positively charged potassium ions flow out of the muscle cell through ion channels in the cell membrane, priming the cell for the next cycle. This new research demonstrates that PAHs can block potassium ion channels in the heart cells of tunas. They can also disrupt calcium ion cycling within isolated muscle cells. Together, these effects are thought to underlie the slowed or irregular heartbeats observed in fish embryos exposed to crude oil.

"When we see these kinds of acute effects at the cardiac cell level," said Barbara Block, who led the team of Stanford University scientists working on this study, "it is not surprising that chronic exposure to oil from spills such as Deepwater Horizon can lead to long-term problems in fish hearts."

The study notes that, because the structure of ion channels is similar in the heart muscle cells of many species, related disruptions might occur in the hearts of other vertebrates.

To demonstrate the effect of PAHs on the cardiac cells of tuna, scientists had to measure the flow of electrical current across the membranes of individual cells. "That requires some very specialized skills and equipment," said John Incardona, another NOAA scientist and a coauthor of the study.

This experimental capacity was provided by the Tuna Research and Conservation Center, jointly operated by Stanford University and the Monterey Bay Aquarium. Scientists there measured the electrical properties of individual heart muscle cells using a "patch clamp" technique, which involves micron-scale glass electrodes.

The Stanford scientists provided expertise in tuna husbandry, cardiac physiology, single-cell electrophysiology, and optical imaging. NOAA's Ecotoxicology Program provided expertise in designing oil exposure studies, and in understa
'/>"/>

Contact: Rich Press
rich.press@noaa.gov
NOAA National Marine Fisheries Service
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
2. Queens scientists seek vaccine for Pseudomonas infection
3. Scientists produce eye structures from human blood-derived stem cells
4. American Society of Plant Biologists honors early career women scientists
5. Brandeis scientists win prestigious prize for circadian rhythms research
6. Scientists discover new method of proton transfer
7. Salk scientists open new window into how cancers override cellular growth controls
8. WileyChina.com - Now Featuring Bespoke Pages for China’s Life Scientists
9. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
10. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
11. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists discover the mechanism of heart failure in fish exposed to oil spills
(Date:1/22/2015)... Fla. , Jan. 13, 2015  Today, FreeWavz ... technology, launched its crowdfunding campaign on Fundable, ... the build of production capacity to meet customer ... Photo - http://photos.prnewswire.com/prnh/20150113/168790 ...
(Date:1/22/2015)... Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD and ... reports on the recent success of the Wocket™ smart wallet at CES ... smart wallet was named as one of the "11 Hot Products at ... Products Launched At CES So Far" by Newseveryday.com and "The top 10 ...
(Date:1/22/2015)... DUBLIN , Jan. 22, 2015 Research and ... the addition of the "Global Wearable Technologies ... Growth, Share, Overview, Trends and Forecast 2014-2020" ... Wearable Technologies are smart devices that can be ...
Breaking Biology News(10 mins):FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2
... clogs waterways around the world has at least one redeeming ... and submarines. The Brazilian fern Salvinia molesta ... its surface is dotted with oddly shaped hairs that trap ... In the November 1 issue of the Journal ...
... , WASHINGTON The magnitude and depth of the ... to determine the extent and severity of ecological damage and ... of Mexico, says an interim report by the National Research ... processes -- such as fisheries production -- in addition to ...
... growing faster, suggesting that at least some forests may be ... While forests elsewhere are thinning from wildfires, insect damage ... trees in the far north of Alaska have grown more ... study has found. The health of forests globally is gaining ...
Cached Biology News:Plant with 'eggbeater' testure inspires waterproof coating 2Plant with 'eggbeater' testure inspires waterproof coating 3New report offers broad approach to assessing impacts of ecological damage 2New report offers broad approach to assessing impacts of ecological damage 3Trees on tundra's border are growing faster in a hotter climate 2Trees on tundra's border are growing faster in a hotter climate 3Trees on tundra's border are growing faster in a hotter climate 4
(Date:2/27/2015)... 2015 Bionomics Limited (ASX:BNO, ADR:BMICY) is to ... BNC105 in patients with metastatic renal cancer at the ... . The data will be presented by Dr. ... Comprehensive Cancer Center in California ... data identifies Ferritin and IL-8 as two baseline biomarkers ...
(Date:2/27/2015)... , Feb. 27, 2015  Steep Hill, the industry ... and internationally, intends to open a full service medical ... Mexico , bringing advanced scientific tools and methodology ... Steep Hill is currently the only laboratory licensed ... potency and contaminant testing in order to meet the ...
(Date:2/26/2015)... , Feb. 26, 2015  23andMe, the leading ... Kate Black as Privacy Officer and Corporate Counsel. ... state privacy laws as well as health care regulations. ... she will be responsible for reviewing, updating and enhancing ... the U.S. and abroad. She joined the company January ...
(Date:2/26/2015)... 26, 2015 Protiviti ( www.protiviti.com ), a ... the Governance Portal , designed to increase the ... (GRC) tasks across multiple business units and projects. The ... customers better align their controls with the COSO ( ... requirements. In response to client feedback, Protiviti has also ...
Breaking Biology Technology:New BNC105 Biomarker Data to be Presented at US Cancer Conference 2New BNC105 Biomarker Data to be Presented at US Cancer Conference 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 5Steep Hill First to Receive Provisional Approval to Establish Laboratory Services for Cannabis Testing in State of New Mexico 223andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 3
... the Genetics Policy Institute  (GPI) joined the Coalition ... curiae ("friend of the court") brief in the United States ... federal funding for human embryonic stem cell research. ... District Court and in the Court of Appeals, the latter ...
... Cord Blood Corporation (NYSE: CO ) ("CCBC" ... collection, laboratory testing, hematopoietic stem cell processing, and stem ... results for the third quarter and first nine months ... Third Quarter of Fiscal 2012 Highlights ...
... a leading provider of medical IT solutions, announced the ... in One EMR/PACS/Practice Management platform at the HIMSS12 meeting ... will enable Medstreaming EMR customers to mine any EMR ... format, including DICOM. "By introducing Web ...
Cached Biology Technology:Genetics Policy Institute (GPI) Files Additional Legal Arguments in Sherley v. Sebelius Stem Cell Case 2China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 2China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 3China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 4China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 5China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 6China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 7China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 8China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 9China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 10China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 11China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 12China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 13China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 14China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2012 15Medstreaming Launches Web-Based Analytics for All in One EMR/PACS/Practice Management Platform at HIMSS 2Medstreaming Launches Web-Based Analytics for All in One EMR/PACS/Practice Management Platform at HIMSS 3
... The new StrepMAB-Immo coated microplates can be ... of SerAla-Strep-tag II fusion proteins for ELISA ... small amounts of such proteins are bound ... graphic on the left) and will not ...
... SPA Screening Assay, 5 x ... eliminate lengthy sample extraction procedures and ... 1.32-84.28 ng/ml (4-256 pmol/ml).Sensitivity: 0.65 ng/ml ... C. Category: Drug Screening & Cellular ...
...
Request Info...
Biology Products: