Navigation Links
Scientists decode genome of painted turtle, revealing clues to extraordinary adaptations
Date:4/10/2013

Humans could learn a thing or two from turtles, and scientists who have just sequenced the first turtle genome uncovered clues about how people can benefit from the shelled creatures' remarkable longevity and ability to survive for months without breathing.

Understanding the natural mechanisms turtles use to protect their heart and brain from oxygen deprivation may one day improve treatments for heart attack and stroke, the researchers said.

UCLA conservation biologist and lead author Brad Shaffer collaborated with the Genome Institute at Washington University in St. Louis and 58 co-authors on the multi-year research project. Their paper, which appears in the journal Genome Biology, describes the genome of the western painted turtle, one of the most widespread and well-studied turtles in the world.

Researchers were somewhat surprised to find that the painted turtle's extraordinary adaptations were not the result of previously unknown genes but of gene networks that are common in vertebrates including humans, said Shaffer, a professor at UCLA's Institute of the Environment and Sustainability (IoES) and UCLA's Department of Ecology and Evolutionary Biology.

"They're the same genes we have, and the turtles are just using them in different ways and really cranking up their activity in most cases," said Shaffer, who also directs the La Kretz Center for California Conservation Science at the IoES.

"Given how extreme their adaptations are, I imagined we would see weird new genes, so I was surprised," he added. "But the fact that they're common means they may have direct relevance to human health conditions, especially those related to oxygen deprivation, hypothermia and possibly longevity."

Inside the turtle genome, the researchers found 19 genes in the brain and 23 in the heart that became more active in low-oxygen conditions, including one that became 130 times more active. These genes, all of w
'/>"/>

Contact: Alison Hewitt
ahewitt@support.ucla.edu
310-206-5461
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. 8 M € from EU to enhance access by scientists to the largest European biobanks
2. CSHL neuroscientists show jumping genes may contribute to aging-related brain defects
3. NYSCF scientists develop new protocol to ready induced pluripotent stem cell clinical application
4. Scientists find government justification of new environmental policy unfounded
5. NYSCF scientists develop 3-D stem cell culture technique to better understand Alzheimers disease
6. UGA discovery may allow scientists to make fuel from CO2 in the atmosphere
7. UT MD Anderson scientists uncover the nuclear life of actin
8. Scientists awarded £3M to study the way Northwest European seas absorb carbon
9. Scientists reveal quirky feature of Lyme disease bacteria
10. Scientists create new tools for battling secondhand smoke
11. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... is developing drugs that are highly effective against a ... patient. Such properties are directly related to the 3D ... have a shape that is perfectly complementary to a ... specificity. Publishing in Nature Chemistry , EPFL scientists ... the 3D structure of bioactive peptides and enhance their ...
(Date:8/31/2014)... is available in French . ... just published in the prestigious Nature Neuroscience journal ... Centre of the Douglas Mental Health University Institute and McGill ... circuitry and dynamic mechanisms controlling memory as well of the ... sub-region named the subiculum. , In 2009, they developed ...
(Date:8/29/2014)... how the repeated climatic shifts over the last ... genetic diversity, a team of researchers led by ... Carnaval developed a new biodiversity metric called "phylogeographic ... the genetic variation within species is restricted in ... of biology, and 14 other researchers from institutions ...
Breaking Biology News(10 mins):A new synthetic amino acid for an emerging class of drugs 2A new synthetic amino acid for an emerging class of drugs 3Memory and Alzheimer's: Towards a better comprehension of the dynamic mechanisms 2CCNY team defines new biodiversity metric 2
... published recently in PLoS One delivers new insight ... rattlesnakes may be engaged in an arms race with opossums, ... long been known to eat venomous snakes, this fact has ... of snake venom. Instead, snake venom is usually seen as ...
... see if you can spot the tallest tree. If you,re in ... there are few and far between, and tend to hunch low ... forests make the exercise a bit more difficult. And in the ... the eye can estimate. Knowing how tall trees can grow ...
... the University of Michigan Comprehensive Cancer Center have found that ... encouraging cancer stem cells to grow. Cancer stem cells ... drive its growth and spread. Traditional cancer treatments do not ... In a study published online in the Journal ...
Cached Biology News:Rapid venom evolution in pit vipers may be defensive 2Rapid venom evolution in pit vipers may be defensive 3MIT: The tallest tree in the land 2MIT: The tallest tree in the land 3Cancer stem cells recruit normal stem cells to fuel ovarian cancer, U-M study finds 2
(Date:9/2/2014)... Australia (PRWEB) September 02, 2014 The ... a cure for chronic tinnitus are seeking support for ... on the Indiegogo platform ( http://igg.me/at/tinaway ), was launched ... be a therapeutic ‘mHealth’ app and is based on ... of a team of biomedical and software engineers, Dr. ...
(Date:8/31/2014)... September 01, 2014 Available spectra ... needs for research and cultivation of a wide ... Valoya’s proprietary LEDs with proven patented and pending ... uncompromised light uniformity in critical applications in contrast ... LEDs. , “Our customers have a large variety ...
(Date:8/29/2014)... Electronic circuits are based on electrons, but one of ... photonic circuits, i.e. circuits based on light (photons) instead ... to create a stream of single photons and control ... sorts of attempts to achieve this control, but now ... creating a steady stream of photons emitted one at ...
(Date:8/29/2014)... Local veterinarian, Dr. Keith Clement, and his ... to participate in an investigational study of donor stem ... of this study is to determine if a single ... arthritically affected joints can help reduce pain and inflammation ... current investigational study must be older than nine months, ...
Breaking Biology Technology:tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 2tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 3tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 4tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 5Breakthrough in light sources for new quantum technology 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2
... Therapeutics S.A.,(Alternext: ALEHT), a drug and diagnostic discovery ... the annual shareholders, meeting of the Company, that ... de Vezin,s appointment as,member of the Supervisory Board, ... has reached the age limit defined in the ...
... 29 ,Anesiva, Inc. (Nasdaq: ANSV ) today ... with Green Vision Company, for,several Middle Eastern countries. ... approved in the U.S. to,provide topical local analgesia ... children three to 18 years of age., ...
... barrier technology from Singapore A*STARs Institute of Materials ... organic light emitting diodes (OLEDs) and solar cells ... other technology available in the market, opening up ... , A team of scientists from Singapores Institute ...
Cached Biology Technology:Frederic Desdouits Appointed Member of the Supervisory Board of ExonHit Therapeutics 2Frederic Desdouits Appointed Member of the Supervisory Board of ExonHit Therapeutics 3Anesiva Announces New Zingo Marketing and Distribution Agreement 2Anesiva Announces New Zingo Marketing and Distribution Agreement 3Nanoengineered barrier invented to protect plastic electronics from water degradation 2Nanoengineered barrier invented to protect plastic electronics from water degradation 3Nanoengineered barrier invented to protect plastic electronics from water degradation 4Nanoengineered barrier invented to protect plastic electronics from water degradation 5
... matrix for the extraction of unwanted ... other macromolecules, Applications: ,Reducing octyl glucoside ... interaction of pure β-adrenergic receptor and ... SDS in 6 M urea/0.05 mM ...
Values of steady state parameters for enzyme activities are determined....
... be used for the identification of potential biomarkers ... and other diseases. Due to the fact that ... it provides an attractive alternative to blood plasma ... ProteoSpin Urine Protein Concentration Micro Kit provides ...
... Antibody Capture Kit eliminates ... optimization steps typically required ... This kit enables the ... multiple antigens based on ...
Biology Products: