Navigation Links
Scientists decode genome of painted turtle, revealing clues to extraordinary adaptations
Date:4/10/2013

Humans could learn a thing or two from turtles, and scientists who have just sequenced the first turtle genome uncovered clues about how people can benefit from the shelled creatures' remarkable longevity and ability to survive for months without breathing.

Understanding the natural mechanisms turtles use to protect their heart and brain from oxygen deprivation may one day improve treatments for heart attack and stroke, the researchers said.

UCLA conservation biologist and lead author Brad Shaffer collaborated with the Genome Institute at Washington University in St. Louis and 58 co-authors on the multi-year research project. Their paper, which appears in the journal Genome Biology, describes the genome of the western painted turtle, one of the most widespread and well-studied turtles in the world.

Researchers were somewhat surprised to find that the painted turtle's extraordinary adaptations were not the result of previously unknown genes but of gene networks that are common in vertebrates including humans, said Shaffer, a professor at UCLA's Institute of the Environment and Sustainability (IoES) and UCLA's Department of Ecology and Evolutionary Biology.

"They're the same genes we have, and the turtles are just using them in different ways and really cranking up their activity in most cases," said Shaffer, who also directs the La Kretz Center for California Conservation Science at the IoES.

"Given how extreme their adaptations are, I imagined we would see weird new genes, so I was surprised," he added. "But the fact that they're common means they may have direct relevance to human health conditions, especially those related to oxygen deprivation, hypothermia and possibly longevity."

Inside the turtle genome, the researchers found 19 genes in the brain and 23 in the heart that became more active in low-oxygen conditions, including one that became 130 times more active. These genes, all of w
'/>"/>

Contact: Alison Hewitt
ahewitt@support.ucla.edu
310-206-5461
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. 8 M € from EU to enhance access by scientists to the largest European biobanks
2. CSHL neuroscientists show jumping genes may contribute to aging-related brain defects
3. NYSCF scientists develop new protocol to ready induced pluripotent stem cell clinical application
4. Scientists find government justification of new environmental policy unfounded
5. NYSCF scientists develop 3-D stem cell culture technique to better understand Alzheimers disease
6. UGA discovery may allow scientists to make fuel from CO2 in the atmosphere
7. UT MD Anderson scientists uncover the nuclear life of actin
8. Scientists awarded £3M to study the way Northwest European seas absorb carbon
9. Scientists reveal quirky feature of Lyme disease bacteria
10. Scientists create new tools for battling secondhand smoke
11. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... its launch in December 2014, the 1U™ app ... trying to remember their usernames and passwords through replacing the ... To assist people who have struggled to remember usernames and ... and focuses on redefining identity, announced today that it is ...
(Date:12/19/2014)... Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced ... Perimeter Security Systems Market" report to their offering. ... American perimeter security market is estimated to grow at a ... market holds a larger share in this market, ...
(Date:12/17/2014)...  HITLAB SM announced today its completion of a ... to current U.S. Food and Drug Administration (FDA) regulations. ... and smart phone application trials utilizing the highest principles ... is determined to improve global healthcare access, quality, and ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... have discovered that the skin is capable of communicating ... and they say that it may help our understanding ... the body. Professor Susanne Mandrup and her research ... the Department of Biochemistry and Molecular Biology at the ...
... common tourist activity, but a new study published online ... that already-imperilled iguanas are suffering further physiological problems as ... Knapp, PhD, of the John G. Shedd Aquarium in ... and endoparasitic infection rates between northern Bahamian rock iguanas ...
... For discoveries about how the brain calculates and remembers where ... University will award the 2013 Louisa Gross Horwitz Prize to ... Norwegian University of Science and Technology in Norway, and John ... Their work, conducted in animal models, may lead to new ...
Cached Biology News:Surprising discovery: The skin communicates with the liver 2Feeding by tourists compromises health of already-endangered iguanas, study finds 2Feeding by tourists compromises health of already-endangered iguanas, study finds 3Columbia's 2013 Horwitz Prize awarded for discoveries that could lead to new Alzheimer's treatments 2Columbia's 2013 Horwitz Prize awarded for discoveries that could lead to new Alzheimer's treatments 3Columbia's 2013 Horwitz Prize awarded for discoveries that could lead to new Alzheimer's treatments 4Columbia's 2013 Horwitz Prize awarded for discoveries that could lead to new Alzheimer's treatments 5
(Date:1/22/2015)... The laboratory information management systems market is a ... technological advancements due to factors such as rising pressure ... healthcare systems, and increasing government support for adoption of ... players in the market focus on technological advancements to ...
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently ... Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... education conference for health care professionals. This year’s pre-conference seminar ... probiotics in health. Dr. Leyer spoke about the emerging topics ...
(Date:1/22/2015)... 22, 2015   Cypher Genomics, Inc., the ... SQNM ), the leading molecular diagnostics ... generation noninvasive prenatal tests (NIPT). Through this agreement, ... Mantis™, to advance analysis of clinically-relevant fetal sub-chromosomal ...
(Date:12/24/2014)... Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... MDT ) has submitted a pre-market approval application ... the use of Medtronic,s SynchroMed ® II implantable ... use with United Therapeutics, Remodulin ® (treprostinil) Injection ...
Breaking Biology Technology:Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4
... feasible and advantageous for the U.S. Army,s Chemical Materials ... secondary waste during regular chemical agent disposal operations, says ... The committee that wrote the report also determined that ... allowing the submission of data from previous trial burns ...
... Scientists at Pacific Northwest National Laboratory,have discovered a ... that,will enable creation of a portable biosensor that ... chemical or nerve agents, the need to quickly ... worried well. , The sensor components resemble a ...
... Within three years, insulin-producing islet cells from pigs may ... finally cure insulin dependant diabetes. , This key ... Director of the Diabetes Institute for Immunology & Transplantation ... documented their medical breakthrough in the prestigious scientific journal ...
Cached Biology Technology:Report recommends off-site disposal of secondary waste 2Report recommends off-site disposal of secondary waste 3Report recommends off-site disposal of secondary waste 4Truly sick or simply scared? 2Breakthrough research identifies how cells from pigs may cure diabetes 2
Antibody specific for histone H3 acetylated at any of the five N-terminal lysine residues. Rabbit polyclonal serum. Antigen: Synthetic peptide derived from histone H3 N-terminal region, mulitpliy...
Request Info...
Immunofixation Gel Kit, requires IF100 Reactivity: Human Applications: Immunofixation ...
Request Info...
Biology Products: