Navigation Links
Saint Louis University researchers discover a way to detect new viruses
Date:6/17/2013

ST. LOUIS -- In research published in Biochemical and Biophysical Research Communications, Saint Louis University researchers describe a technology that can detect new, previously unknown viruses. The technique offers the potential to screen patients for viruses even when doctors have not identified a particular virus as the likely source of an infection.

In the new approach, scientists use blood serum as a biological source to categorize and discover viruses.

Taking advantage of the complete deciphering of the human genome, SLU researchers used a next-generation sequencing (NGS) approach called transcriptome subtraction. With this process, the research team subtracted the entire human genetic sequence from the genetic material in the blood they were examining. By studying what remained, they were able to identify viral genetic material in the blood.

"We have discovered a technology that allows us to detect new viruses," said Adrian Di Bisceglie, M.D., chairman of the department of internal medicine at Saint Louis University. "We isolate DNA and RNA, amplify the amount of genetic material present in the blood, do ultra-deep sequencing and use an algorithm to search for matches for every known piece of genetic code, both human and for microbes.

"Once we remove the known portions, we're ultimately left with new viruses."

When doctors suspect that a patient has a viral infection, it can be difficult to determine which virus is the culprit.

One way to test for the presence of a virus is to grow it in the lab from a biological sample, like tissue or blood, from the patient. However, that approach won't work if tissue isn't available, if there is no logical starting place for deciding which viruses to screen for (such as knowing that a patient was exposed to a particular virus), or in a "hit and run" viral infection, in which case there is a narrow time frame for tissue sampling.

Another o
'/>"/>

Contact: Carrie Bebermeyer
bebermcl@slu.edu
314-977-8015
Saint Louis University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. From scourge to saint: E. coli bacteria becomes a factory - to make cheaper, faster pharmaceuticals
2. Vitamin D holds promise in battling a deadly breast cancer, Saint Louis University researchers say
3. In a fight to the finish, Saint Louis University research aims knockout punch at hepatitis B
4. Saint Louis University, University of Toronto biologists help decode turtle genome
5. BP Deepwater Horizon oil spill exacerbated existing environmental problems in Louisiana marshes
6. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
7. Louisiana Tech University professor earns national honor from Society of American Foresters
8. University of Houston study shows BP oil spill hurt marshes, but recovery possible
9. University of Alberta led research may have discovered how memories are encoded in our brains
10. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
11. Marshall University study may lead to new treatments for prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... Carolina , 5. Februar 2015 /PRNewswire/ ... als spezialisiertes Logistikunternehmen und hat eine neue ... klinische Logistikfirma (Clinical Logistics Organization – CLO) ... neuen Kampagne lautet First , mit ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... Jan. 26, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce ... ( http://www.nxt-id.com/ ) as part of its 2015 marketing ... Company launched its new consumer website for Wocketwallet.com earlier ... CEO of NXT-ID said, "Our new corporate website naturally ...
(Date:2/5/2015)... 28, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce ... Global Online CEO Conference on January 29 th ... Pereira , CEO of NXT-ID will present and host ... Wocket smart wallet and its full suite of biometric ...
Breaking Biology News(10 mins):Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 2CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 3
... was lost in the shadows of cancer research for decades ... Mina Bissell, Distinguished Scientist with Berkeley Lab,s Life Sciences Division ... aerobic glycolysis - glucose metabolism in the presence of oxygen ... malignant cells but is itself a cancerous event. "A ...
... and said about "platinum" open access as a step beyond ... has been seen of its practical implementation. On 1 January ... Deutsche Entomologische Zeitschrift and Zoosystematics and Evolution ... joining the journal publishing platform of Pensoft Publishers and adopting ...
... Halomonas are a hardy breed of bacteria. ... and pressures that would kill most other organisms. These traits ... sandstone formations that also happen to be useful for hydrocarbon ... The analysis , the first unobstructed view of ...
Cached Biology News:Role for sugar uptake in breast cancer revealed 2Role for sugar uptake in breast cancer revealed 32 of the oldest German journals in Zoology go for 'platinum' open access 2Oil- and metal-munching microbes dominate deep sandstone formations 2
(Date:2/26/2015)... NY (PRWEB) February 26, 2015 According ... Research “Agricultural Biotechnology Market For Transgenic Crops (Corn, Soybean, ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast, ... at USD 15,300 million in 2012 and is expected ... a CAGR of 9.5% from 2013 to 2019. ...
(Date:2/26/2015)... , Feb. 26, 2015 Tauriga Sciences, ... sciences company with interests in the natural wellness sector ... announced today that its products will be featured at ... Capital Partners, 27 th Annual Growth Stock Conference ... located at 1 Ritz Carlton Drive, Dana ...
(Date:2/26/2015)... 26, 2015 CytomX, a biotechnology company developing ... that Sean McCarthy , D. Phil., chief executive ... Cowen and Company 35 th Annual Health Care ... presentation will take place at 4 p.m. EST on ... CytomX Therapeutics develops Probody™ therapeutics for the treatment of ...
(Date:2/25/2015)... 25, 2015 /CNW/ - Radient Technologies Inc. (TSX-V: RTI) (the ... results for the third quarter of its fiscal year ... Discussion and Analysis, and the CEO & CFO certifications ... 31, 2014 are available on www.SEDAR.com ... The Corporation is also pleased to announce the appointment ...
Breaking Biology Technology:Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 2Global Agricultural Biotechnology Market is Expected to Reach USD 28,694.1 Million in 2019 : Transparency Market Research 3SEC Compliance Featuring Products From Tauriga Sciences, Inc. at ROTH Capital Conference 2SEC Compliance Featuring Products From Tauriga Sciences, Inc. at ROTH Capital Conference 3SEC Compliance Featuring Products From Tauriga Sciences, Inc. at ROTH Capital Conference 4Radient Technologies Inc. Releases Third Quarter Results and Appoints New Interim CFO 2
... Germany and MILAN, October 18, 2011 ... at EuroSpine Milan for the first time, opening up ... For the first time joimax® presents the ... the novel pain therapy product "Multiuse". The new Multiuse-Set ...
... TARRYTOWN, N.Y., Oct. 17, 2011 Regeneron Pharmaceuticals, Inc. ... it intends to offer, subject to market and other ... notes due 2016 in a private placement.  The notes ... qualified institutional buyers pursuant to Rule 144A under the ...
... Cellular Dynamics International (CDI) today announced that it ... Wall Street Journal Technology Innovation Awards. ... are determined by a panel of independent judges who evaluated ... the award in 16 categories.  Of these, the panel chose ...
Cached Biology Technology:joimax® Launches Numerous Innovations at EuroSpine Milan From 19 To 21 October 2011 2Regeneron Pharmaceuticals Announces Proposed Offering of Convertible Senior Notes due 2016 2Regeneron Pharmaceuticals Announces Proposed Offering of Convertible Senior Notes due 2016 3Regeneron Pharmaceuticals Announces Proposed Offering of Convertible Senior Notes due 2016 4Regeneron Pharmaceuticals Announces Proposed Offering of Convertible Senior Notes due 2016 5Cellular Dynamics International's (CDI) Human Induced Pluripotent Stem Cell (iPSC) Technology Named the Gold Winner in The Wall Street Journal 2011 Technology Innovation Awards 2
Request Info...
Mouse monoclonal [DJR3] to DcR1 (Biotin) ( Abpromise for all tested applications). entrezGeneID: 8794 SwissProtID: O14798...
...
Rabbit polyclonal to Quinolinic acid ( Abpromise for all tested applications). Antigen: Synthetic quinolinic acid conjugated to bovine serum albumin....
Biology Products: