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Saint Louis University, University of Toronto biologists help decode turtle genome
Date:4/23/2013

a great model to study the ways we can protect human brain from the debilitating effects of stroke," Buck said. "And there's more. When faced with low oxygen conditions it rapidly lowers metabolism by over 90 percent, similar to the effect of anesthetics during human surgeries. It may therefore also be a natural anesthetic model in which we can explore safer forms on anesthesia."

"Our RNA sequencing data in the genome paper reveals over 13000 genes in common with humans and 19 genes that increase their activity in turtle brain and 23 in heart following 24 hours of anoxia. One even increases 130 fold above controls giving us excellent leads to follow in our study of the mechanisms underlying natural anoxia tolerance," Buck added.


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Contact: Christine Elias
christine.elias@utoronto.ca
University of Toronto
Source:Eurekalert

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