Navigation Links
Rutgers Genetics receives $7.8 million for autism research
Date:9/5/2007

d communications skills; but there is a broad spectrum of symptoms and characteristics, expressed in combinations from extremely mild to quite severe.

Most scientists agree that there is a genetic basis for autism, with an assortment of environmental factors possibly conspiring with the altered genes to produce the many forms of the disorder. Many believe that genetic analyses will point the way for future research and potential therapies.

The Simons Simplex Collection will supply the groundwork for a different approach to autism genetics. The strategy is based on the premise that new genetic alterations occur in the germ line (sperm or eggs) of one of the parents, but they are not found in other tissues of the parents. Such new or sporadic mutations may account for a large fraction of autism cases. They may also explain why the incidence of autism increases with parental age.

Tischfield said that, in general, there may be several different kinds of genetic deficiencies in autism and that many cases may not be due to mutations that are passed on from generation to generation, as in other disorders , such as cystic fibrosis or hemophilia. Consistent with this, geneticists are finding that in sporadic autism cases, where there are no other affected children, there is a high frequency of relatively large, new DNA deletions that are probably not inherited.

You do not find them in the parents and that is the key, Tischfield said. To find individuals with sporadic mutations the project will seek out families with only one affected child. In a family where several children display autism, there is probably a defect in a gene that is inherited in the usual sense.

Clinicians and scientists working with the Simons Simplex Collection are establishing new and rigorous diagnostic criteria to ensure that the selected individuals represent this sporadic type of autism. Molecular tests will eliminate individuals with other dis
'/>"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x652
Rutgers, the State University of New Jersey
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Rutgers to lead $52.7 million protein research program
2. Rutgers researchers scientifically link dancing ability to mate quality
3. Rutgers researchers find fat gene
4. FDA approves first medical device using rutgers biomaterial
5. Mosaic mouse technique offers a powerful new tool to study diseases and genetics
6. Genetics links whale to two different ocean basins
7. New technique could alter field of mouse genetics
8. Scientists unpick genetics of first 15 minutes of life
9. New research examines genetics of successful aging
10. Alcoholism, smoking and genetics among Plains American Indians
11. New research examines genetics of successful aging
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... 2014 This report covers the specifics of ... in heavy pursuit of research due to its versatility ... to other RNA components. miRNA,s non-coding nature and ability ... for use as a biomarker for a variety of ... diagnostics for the advancement in therapeutic development. Furthermore there ...
(Date:10/25/2014)... , Oct. 23, 2014 Research ... "Biometrics Market in Europe 2014-2018" report to their ... helps to assess individuals on the basis of their ... identification of both physiological traits such as fingerprints, face ... and behavioral traits such as keystroke patterns and speech ...
(Date:10/22/2014)... , Oct. 20, 2014 The Nano-Bio ... States Air Force Research Laboratory (AFRL), has chosen a ... (AzCIM) at the University of Arizona College of Medicine ... funding.  The AzCIM project,s goal is to assess different ... collect different volumes of sweat under a variety of ...
Breaking Biology News(10 mins):MicroRNA: An Insight to miRNA-based microarrays, diagnostics and therapeutics Overview, Cambridge Healthtech Advisors 2Biometrics Market in Europe 2014-2018: Key Vendors are 3M Cogent, Cognitec, NEC and Safran 2Biometrics Market in Europe 2014-2018: Key Vendors are 3M Cogent, Cognitec, NEC and Safran 3Nano-Bio Manufacturing Consortium Selects Project Proposed by Arizona Center for Integrative Medicine to Optimize Human Performance Monitoring Techniques 2Nano-Bio Manufacturing Consortium Selects Project Proposed by Arizona Center for Integrative Medicine to Optimize Human Performance Monitoring Techniques 3
... fossil discovered in Tunisia represents the oldest known ancestor of ... mammals. The find is described in research published January 16 ... Julien Benoit and colleagues from the University of Science and ... cow ancestors have been found in Jamaica, but the Tunisian ...
... are facing a troubling consequence of their own success. They ... life expectancy. However, those same drugs will eventually cause the ... current treatments. With a new $3.4 million grant from ... leading a team of researchers who want to stay a ...
... launch pad or even in orbit. They start years before ... to expand our view and understanding of the planet. NASA ... for the Aerosol-Cloud-Ecosystem (ACE) mission, a satellite that "will dramatically ... clouds and aerosols," said ACE science lead David Starr of ...
Cached Biology News:Researchers attack HIV's final defenses before drug-resistant mutations emerge 2Researchers attack HIV's final defenses before drug-resistant mutations emerge 3PODEX experiment to reshape future of atmospheric science 2PODEX experiment to reshape future of atmospheric science 3PODEX experiment to reshape future of atmospheric science 4PODEX experiment to reshape future of atmospheric science 5
(Date:10/25/2014)... (PRWEB) October 25, 2014 Berkshire ... is pleased to announce the release of the ... highest level of contamination containment in critical processing ... 3 and higher cleanroom environments, ValuSeal® IonX™ is ... knit laundered wiper that continues Berkshire’s innovative focus ...
(Date:10/25/2014)... , Oct. 24, 2014  RegeneRx Biopharmaceuticals, Inc. (OTCBB: RGRX) ... at the Fourth International Symposium on Thymosins in Health ... "When thymosin beta 4 (TB4) linked ... the peritoneal cavity in a rodent model of stroke, ... the brain parenchyma (the functional tissue of the brain). ...
(Date:10/25/2014)... October 24, 2014 ... ) has announced the addition of the  ... And Other 2-D Nanomaterials "  report to ... , ,CNTs and graphene are the strongest, ... man, with a performance-per-weight greater than any ...
(Date:10/22/2014)... and BOSTON , Oct. 22, ... a leading global specialty pharmaceutical company, and Rhythm, a ... an exclusive option to acquire Rhythm,s wholly owned subsidiary, ... peptide ghrelin agonist, for the treatment of diabetic gastroparesis ... has completed a successful Phase 2 trial of relamorelin ...
Breaking Biology Technology:Ions Are Bygones, Berkshire Announces the Release of New Innovative Cleanroom Wipers 2Researchers Report Thymosin Beta 4 Crosses Blood-Brain Barrier In Animal Stroke Model 2The Global Market for Carbon Nanotubes, Graphene and Other 2-D Nanomaterials 2The Global Market for Carbon Nanotubes, Graphene and Other 2-D Nanomaterials 3The Global Market for Carbon Nanotubes, Graphene and Other 2-D Nanomaterials 4Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 2Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 3Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 4Actavis Signs Option to Acquire Rhythm Subsidiary and its GI Development Product, Relamorelin 5
... YM BioSciences Inc. (NYSE Amex: YMI ; TSX: ... patients enrolled in the Phase I/II trial for its JAK1/JAK2 ... an oral presentation at the 52nd American Society of Hematology ... "Anemia is the most serious symptom associated with myelofibrosis, so ...
... Viruses have a bad rep—and rightly so. The ... itself makes it a destructive scourge to animals and ... the University of Maryland,s A. James Clark School of ... together by Professor Reza Ghodssi, is turning the tables, ...
... YORK, Dec. 6, 2010 See video from ... Novartis announced 24-month data showing that ... the treatment of adult patients with newly diagnosed ... chronic phase1. These new data, from the first ...
Cached Biology Technology:YM BioSciences Reports Positive Interim Data Including Substantial Anemia Response from Phase I/II Trial of JAK1/JaK2 Inhibitor CYT387 2YM BioSciences Reports Positive Interim Data Including Substantial Anemia Response from Phase I/II Trial of JAK1/JaK2 Inhibitor CYT387 3YM BioSciences Reports Positive Interim Data Including Substantial Anemia Response from Phase I/II Trial of JAK1/JaK2 Inhibitor CYT387 4YM BioSciences Reports Positive Interim Data Including Substantial Anemia Response from Phase I/II Trial of JAK1/JaK2 Inhibitor CYT387 5YM BioSciences Reports Positive Interim Data Including Substantial Anemia Response from Phase I/II Trial of JAK1/JaK2 Inhibitor CYT387 6Bad Virus Put to Good Use: Breakthrough Batteries 2Bad Virus Put to Good Use: Breakthrough Batteries 3Bad Virus Put to Good Use: Breakthrough Batteries 4Bad Virus Put to Good Use: Breakthrough Batteries 5Bad Virus Put to Good Use: Breakthrough Batteries 6
... (EMSA) is a powerful tool for evaluating ... shift or gel retardation, the assay is ... to electrophoresis, free DNA will migrate differently ... Chemiluminescent EMSA Kit is a nonradioactive system ...
... The Cell Lab Quantas unique combination ... unsurpassed population resolution capabilities and accurate ... multiple excitation wavelengths, including UV, allowing ... of multi-color applications typically only achievable ...
... novel procedure for the uniform amplification and ... DNA from small samples. This method has ... highly reproducible amplification and labeling procedure for ... Mini Kit module (QIAGEN) and a ULS ...
... using PULSin may be superior to transfection ... traditional transfection, with PULSin you can study ... time course of proteins in cells. Likewise, ... information than traditional RNA interference experiments. ...
Biology Products: