Navigation Links
Rich or poor in gut bacteria brings new vision for obesity treatment
Date:8/29/2013

Shenzhen, China -- The MetaHIT consortium, comprised of Institute National de la Recherche Agronomique (INRA), University of Copenhagen, BGI, and other institutes, has investigated the gut microbial composition in a cohort of 123 non-obese and 169 obese Danish individuals. This study showed for the first time that 2 groups of individuals can be distinguished in the population by the richness of gut microbiota. The latest results were published online in Nature today.

Obesity, known as "the modem civilized disease", is a leading preventable cause of death worldwide that increases the likelihood of various diseases, particularly heart disease, type 2 diabetes, and others. It's reported that the obesity epidemic will affect more than 700 million in 2015 and will continue to grow. Each of our guts is colonized by more than 3 pounds of microorganisms. More and more data show that our "other" genome, the microbiome, may have greater consequences on the onset of obesity.

In this study, researchers analyzed the gut bacterial composition of 292 Danish adults by a new analytical approach called quantitative metagenomics. They found two groups of individuals that differ by the number of gut microbial genes and thus gut bacterial richness. A quarter of the cohort is "poor" in bacteria (low bacterial richness), whereas the rest is "rich" (high bacterial richness); Low richness individuals included a significantly higher proportion of obese participants and were as a group characterized by a more marked adiposity.

Their further efforts showed that the low richness microbiota contains higher proportion of pro-inflammatory and lower proportion of anti-inflammatory bacterial species than the high richness one. The two groups of individuals could be almost perfect stratified with very few bacteria, suggesting that simple molecular diagnostic tests, based upon the gut microbiome, can be developed to identify individuals at risk of common morbidi
'/>"/>

Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen
Source:Eurekalert

Page: 1 2

Related biology news :

1. Bacterial toxins cause deadly heart disease
2. UC Davis researchers discover molecular target for the bacterial infection brucellosis
3. High-angle helix helps bacteria swim
4. Newly discovered bacterial partnership changes ocean chemistry
5. Bacterial blockade
6. Study finds depletion of alveolar macrophages linked to bacterial super-infections
7. New methods to visualize bacterial cell-to-cell communication
8. Bacteria from Salar de Uyuni in Bolivia conceal bioplastic
9. CWRU dental researchers NIDCR grant targets oral bacteria and fetal death link
10. Genomes of cholera bacteria from Haiti confirm epidemic originated from single source
11. UT study: Chemical in antibacterial soaps may harm nursing babies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... -- C-Labs LLC, a leading provider of remote and ... announced the appointment of John Traynor to ... advisor to the firm, Mr. Traynor will now oversee ... out of the C-Labs office in Redmond, ... , Chief Executive Officer. Photo - ...
(Date:11/18/2014)... 2014 The Parenteral Drug Association (PDA) today confirmed ... speak and at least seven more will participate in the ... Shoreham Hotel in Washington D.C. , Dec. ... significant support from the regulatory agencies in the ... in our effort to help advance the use of metrics ...
(Date:11/11/2014)... CHICAGO , Nov. 11, 2014  Forensicon, Inc., ... eDiscovery firm, is pleased to announce the promotion of ... to Director of Digital Forensics. In Schiff,s new role ... out the team of digital forensics examiners and provide ... Photo - http://photos.prnewswire.com/prnh/20141110/157719 ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2
... November 18, 2009Quantitative polymerase chain reaction (qPCR) technology ... expansion as a result of advances such as ... optimization-free multiplexing, reports Genetic Engineering & Biotechnology News ... simultaneously quantify specific DNA sequences is increasing its ...
... moa, a giant extinct bird, has revealed a new geological ... in the Proceedings of the National Academy of Sciences ... University of Adelaide has reconstructed a history of marine barriers, ... of years, using the first complete genetic history of the ...
... , , KIEV, Ukraine, Nov. 17 ... including designer fashions, precious gems, antiques and fine art, has ... around the world. The International Chamber of Commerce estimates ... However, an exciting new technology can give brands and ...
Cached Biology News:Extinct moa rewrites New Zealand's history 2Innovative Document Security Technology Proves Powerful in Avoiding Counterfeit Products 2Innovative Document Security Technology Proves Powerful in Avoiding Counterfeit Products 3
(Date:12/17/2014)...  United Therapeutics Corporation (NASDAQ: UTHR ) ... changes to Martine Rothblatt , Ph.D,s compensation program. ... United Therapeutics announced the promotion of Roger Jeffs ... David Zaccardelli , Pharm.D. to Executive Vice President ... Dr. Rothblatt,s title will change from Chairman and Chief ...
(Date:12/17/2014)... Calif. , Dec. 17, 2014 ... a Phase 2 study evaluating the investigational oral ... of patients with severe, chronic itch who are ... of care, including topical steroids and antihistamines. ... change in Visual Analog Scale (VAS) itch score ...
(Date:12/15/2014)... 15, 2014 METTLER TOLEDO is ... tool, ParticleView V19 with PVM technology , ... particle vision and measurement tool continuously captures high-resolution ... ParticleView V19 then automatically prepares a report pairing ... size and concentration changes. This compelling blend of ...
(Date:12/15/2014)... SAN DIEGO , Dec. 15, 2014 /PRNewswire/ ... a three-dimensional biology company focused on delivering breakthrough ... by the industry and collaborators of its exVive3D ... was made widely available in full commercial release ... in the field, resulting in several awards for ...
Breaking Biology Technology:United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 3United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 4Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4New Real-Time In Situ Probe-Based Video Microscope from METTLER TOLEDO 2Organovo Celebrates a Positive 2014 Reception of its exVive3DTM Human Liver Tissue Product 2Organovo Celebrates a Positive 2014 Reception of its exVive3DTM Human Liver Tissue Product 3
... Nov. 10, 2011 ChemoCentryx, Inc. today announced positive ... 44th Annual Meeting of the American Society of Nephrology. ... robust improvements of albuminuria, serum markers of renal function, ... poster presentation titled "CCR2 Inhibition in Diabetic Mice Results ...
... CRANBURY, N.J., Nov. 10, 2011 Palatin Technologies, Inc. (NYSE ... fiscal year 2012 financial results on Tuesday, November 15, 2011 ... Palatin will also conduct a conference call and live audio ... 2011, which will include discussion of the results of operations ...
... a material that absorbs on average more than 99 ... that hits it -- a development that promises to ... of engineers at NASA,s Goddard Space Flight Center in ... Optics and Photonics conference, the largest interdisciplinary technical meeting ...
Cached Biology Technology:ChemoCentryx Presents Positive Results for Novel CCR2 Inhibitor in Preclinical Models of Diabetic Nephropathy at the 44th Annual Meeting of the American Society of Nephrology 2ChemoCentryx Presents Positive Results for Novel CCR2 Inhibitor in Preclinical Models of Diabetic Nephropathy at the 44th Annual Meeting of the American Society of Nephrology 3Palatin Technologies, Inc. to Report Fiscal Year 2012 First Quarter Results; Teleconference and Webcast to be held on November 15, 2011 2NASA develops super-black material that absorbs light across multiple wavelength bands 2NASA develops super-black material that absorbs light across multiple wavelength bands 3
... binding specificity and signaling of the members ... be modified by alternative splicing--which has important ... you can perform a classical expression profiling ... different alternatively spliced forms of the gene ...
Mouse monoclonal antibody raised against a partial recombinant ST3GAL2. NCBI Entrez Gene ID = ST3GAL2...
... Visualizer Extraction Kit is manufactured for DNA ... damage byexposure to UV light. The Purification ... often used for DNA-cloning work. The conventional ... and exposure of UV light damages DNA ...
CleanBox DNA workstation with two 254nm UV lambs & 12-hr timer, 90cm (36-inch)width, single door, 115V (w/crating)...
Biology Products: