Navigation Links
Researchers identify a new gene with a key role in obesity and diabetes
Date:1/10/2013

Scientists observed that blocking the expression of the gene TRIP-Br2 in mice protects them against obesity and insulin resistance. The study shows that the gene modulates fat storage by regulating energy expenditure and lipolysis, the process which transforms fat into lipids for the body's energy consumption. If the gene expression is blocked, the mice increase their lipolysis and their energy expenditure, thus reducing their obesity.

Obesity is the result of an alteration in the processes that regulate food absorption and energy production. This alteration tips the balance towards excessive storage of fat. According to the researchers, understanding the regulation of the factors that control the storage, mobilisation and use of excess energy in fat cells (the adipocytes) can lead to the development of therapies for obesity and its related illnesses, such as type 2 diabetes.

In the words of Cristina Mallol, a researcher at the Universitat Autnoma de Barcelona and co-author of the study: "The protection of mice with no expression of the gene TRIP-Br2, and its selective elevation in the visceral fat of humans point the way to a future gene therapy to counteract obesity, insulin resistance and excess lipids in the blood".


'/>"/>

Contact: Octavi Lpez Coronado
octavi.lopez@uab.cat
34-935-813-301
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1

Related biology news :

1. GW researchers find variation in foot strike patterns in predominantly barefoot runners
2. Joslin researchers identify important factor in fat storage and energy metabolism
3. UCSB researchers perform pioneering research on Type 2 diabetes
4. Researchers develop tool to evaluate genome sequencing method
5. Jackson Laboratory researchers provide definitive proof for receptors role in synapse development
6. Researchers discover genetic basis for eczema, new avenue to therapies
7. Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer
8. Carin Görings remains identified by researchers at Uppsala University
9. CNIO researchers develop new databases for understanding the human genome
10. 3 Johns Hopkins researchers named AAAS Fellows
11. Leibniz Prizes 2013: DFG honors 11 outstanding researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... 28, 2017 The report "Video ... Monitors, Servers, Storage Devices), Software (Video Analytics, VMS), and ... Global Forecast to 2022", published by MarketsandMarkets, the market ... is projected to reach USD 75.64 Billion by 2022, ... The base year considered for the study is 2016 ...
(Date:3/23/2017)... PUNE, India , March 23, 2017 The report ... Equipment, Touchless Biometric), Industry, and Geography - Global Forecast to 2022", published by ... growing at a CAGR of 29.63% between 2017 and 2022. ... ... Logo ...
(Date:3/22/2017)... LIVERMORE, Calif. , March 21, 2017 ... recognition analytics company serving law enforcement agencies, announced today ... Sheridan as director of public safety business development. ... of diversified law enforcement experience, including a focus on ... Vigilant. In his most recent position, Mr. Sheridan served ...
Breaking Biology News(10 mins):
(Date:7/13/2017)... ... July 13, 2017 , ... Thousands of pilots from across the country will ... Championships (Nats). Pilots come to Muncie to compete in various categories of model flying ... that participate in world championships. , RC Pylon (July 14-21): One of the most ...
(Date:7/13/2017)... ... July 13, 2017 , ... ... in Orthopedics, has announced today the completion of a major transaction with Eurazeo ... organic and external growth. The alliance fuels In’Tech Medical’s service offerings while leveraging ...
(Date:7/13/2017)... Frederick, Maryalnd (PRWEB) , ... July 13, 2017 ... ... Frederick Innovative Technology Center, Inc. (FITCI), has experienced robust growth in the past ... the public/private nonprofit has launched several Entrepreneurial Acceleration Programs and expanded its board ...
(Date:7/13/2017)... ... July 13, 2017 , ... Trinity Sterile, Inc., a fast-growing ... has chosen The Copley Consulting Group to implement and deploy the Infor CloudSuite ... internal and backend operations to streamline efficiencies to meet the increasing demand for ...
Breaking Biology Technology: