Navigation Links
Researchers identify a new gene with a key role in obesity and diabetes
Date:1/10/2013

Scientists observed that blocking the expression of the gene TRIP-Br2 in mice protects them against obesity and insulin resistance. The study shows that the gene modulates fat storage by regulating energy expenditure and lipolysis, the process which transforms fat into lipids for the body's energy consumption. If the gene expression is blocked, the mice increase their lipolysis and their energy expenditure, thus reducing their obesity.

Obesity is the result of an alteration in the processes that regulate food absorption and energy production. This alteration tips the balance towards excessive storage of fat. According to the researchers, understanding the regulation of the factors that control the storage, mobilisation and use of excess energy in fat cells (the adipocytes) can lead to the development of therapies for obesity and its related illnesses, such as type 2 diabetes.

In the words of Cristina Mallol, a researcher at the Universitat Autnoma de Barcelona and co-author of the study: "The protection of mice with no expression of the gene TRIP-Br2, and its selective elevation in the visceral fat of humans point the way to a future gene therapy to counteract obesity, insulin resistance and excess lipids in the blood".


'/>"/>

Contact: Octavi Lpez Coronado
octavi.lopez@uab.cat
34-935-813-301
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1

Related biology news :

1. GW researchers find variation in foot strike patterns in predominantly barefoot runners
2. Joslin researchers identify important factor in fat storage and energy metabolism
3. UCSB researchers perform pioneering research on Type 2 diabetes
4. Researchers develop tool to evaluate genome sequencing method
5. Jackson Laboratory researchers provide definitive proof for receptors role in synapse development
6. Researchers discover genetic basis for eczema, new avenue to therapies
7. Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer
8. Carin Görings remains identified by researchers at Uppsala University
9. CNIO researchers develop new databases for understanding the human genome
10. 3 Johns Hopkins researchers named AAAS Fellows
11. Leibniz Prizes 2013: DFG honors 11 outstanding researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/12/2015)... BERLIN , March 12, 2015 ... IAM, a standardized identity and access management (IAM) ... reliable implementation schedule. With Beta System,s new IAM ... and best practices gleaned from multiple IAM implementations ... includes the software as well as any necessary ...
(Date:3/10/2015)... , March 10, 2015 ... "Personalized Medicine in Human Space Flight" ... Thomas J. Goodwin , Ph.D. was recently featured ... the past two years. Specifically, "Personalized Medicine ... downloaded scientific papers published in 2013 and 2014 from ...
(Date:3/3/2015)... , March 3, 2015 Cryoport, ... of advanced cryogenic logistics solutions for the ... stem cells, cell lines, clinical research organizations, ... today announced the expansion of its relationship ... ("Fred Hutch") Clinical Research Division with ...
Breaking Biology News(10 mins):Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 2Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 3
... WASHINGTON, Oct. 18 Can skin cancer be treated ... Irvine), believe so. They,re exploring new ways to image cancerous ... cancer called photodynamic therapy (PDT) -- work that they will ... in Optics (FiO) 2010 at the Rochester Riverside Convention ...
... Health (NIH) have determined the complete genetic blueprints for ... bacteria that cause Lyme disease. The achievement should lead ... strains may result in different courses of illness in ... in North America. The wealth of new genetic data ...
... University of Michigan Heath System and their collaborators have ... help guide new treatments for psoriasis, one of the ... Using cutting-edge methods to peer into the hidden genetic ... published in Nature Genetics, further maps the ...
Cached Biology News:Treating cancer with light 2Four new psoriasis 'hotspots' identified by U-M geneticists 2
(Date:3/25/2015)... and REYKJAVIK, Iceland , March 25, ... using the genome to create better medicine, today congratulated the ... studies of whole-genome data yet undertaken. The ... – are built around the most comprehensive population-wide ... of deCODE scientists led by Kari Stefansson , deCODE,s ...
(Date:3/25/2015)... 2015 Having added two International locations ... of 2014, ITRA Global proudly announced recently the organization’s ... Representative Alliance, based in the United States, is one ... occupiers of commercial real estate. , Saltwood International ... Poland that exclusively advises occupiers of office space, ensuring ...
(Date:3/25/2015)... TORONTO , March 25, 2015 /CNW/ - ... winners of the 2015 Canada Gairdner Awards, recognizing some ... the world. Among the world,s ... a leader in science and provide a $100,000 (CDN) prize ... promote a stronger culture of research and innovation ...
(Date:3/25/2015)... 25, 2015  CASI Pharmaceuticals, Inc. (Nasdaq: CASI ... and commercialization of innovative therapeutics addressing cancer and other ... commercial focus on China , announces ... its target therapy drug candidate ENMD-2076 in triple-negative breast ... of Medical Sciences in Beijing , ...
Breaking Biology Technology:Landmark deCODE Studies Demonstrate the Power of Truly Big Genomics for Improving Medicine Worldwide 2International Organization Expands its Global Reach to Warsaw, Poland 22015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 22015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 32015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 42015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 52015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 62015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 72015 Canada Gairdner Awards Honour Top Medical Discoveries Around The World 8CASI Pharmaceuticals Announces Initiation Of A Phase 2 Trial With ENMD-2076 In Triple-Negative Breast Cancer In China 2CASI Pharmaceuticals Announces Initiation Of A Phase 2 Trial With ENMD-2076 In Triple-Negative Breast Cancer In China 3CASI Pharmaceuticals Announces Initiation Of A Phase 2 Trial With ENMD-2076 In Triple-Negative Breast Cancer In China 4CASI Pharmaceuticals Announces Initiation Of A Phase 2 Trial With ENMD-2076 In Triple-Negative Breast Cancer In China 5
... Massachusetts and LAUSANNE, Switzerland, August 6 /PRNewswire/,-- Curis, ... development company focused on,developing proprietary targeted medicines for ... companies with a focus on the development of,prescription ... that they,have entered into a worldwide, exclusive license ...
... China, Aug. 6 /PRNewswire-Asia-FirstCall/ -- China Sky One Medical,Inc. ... CSKI ), a leading,fully integrated pharmaceutical company producing ... announced the appointment of Mr.,William Wei Lee as an ... effective August 4, 2009. Mr. Jiang Qi-Feng resigned from ...
... 6 Interleukin Genetics, Inc. (NYSE Amex: ... conference call and webcast on Thursday, August 13, 2009, at 4:30 ... financial results. , , To access the live ... replay access of the teleconference will be available on the Investors ...
Cached Biology Technology:Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 2Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 3Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 4Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 5Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305 6China Sky One Medical, Inc. Appoints New Independent Director 2China Sky One Medical, Inc. Appoints New Independent Director 3
Caspr2 Antigen: Fusion protein amino acids 96-1265 (extracellular domain) of human Caspr2 Accession Number: NP_054860...
... (3-D-Gluconamidopropyl)deoxycholamide White solid. HYGROSCOPIC. A ... Has reduced electrostatic interactions that do not ... Aggregation number: 8-16. Purity: ≥95% by ... Aggregation number 8 - 16, CMC 1.1 ...
... 2000 Pipette is a synonym for pipetting ... robust design, and superior operating comfort. Its ... the measuring stroke and blow-out as well ... system ensures utmost accuracy and precision. Ejection ...
... Goat polyclonal to PAX3 This protein ... (PAX) family of transcription factors. Members of ... box domain and a paired-type homeodomain. These ... Mutations in paired box gene 3 are ...
Biology Products: