Navigation Links
Researchers find a new gene expression mechanism of PRRS virus
Date:5/12/2014

am of the shifted site to be read differently and produce a new protein that has a different function."

With the most recent study, Fang and colleagues have shown that this -2 frameshifting requires a PRRS virus protein, nsp1beta. It is the first time a virus's genetic mechanism has been found to require the action of a transacting viral protein rather than a RNA structure to induce a ribosomal frameshifting, which is novel in the protein translation field.

The function of the nsp2TF protein is currently under investigation, Fang said. The protein contains a genetic element that may be responsible for suppressing the pig's immune system.

The newly identified ribosomal frameshifting mechanism may provide an additional antiviral target. Fang's research lab cloned the PRRS virus and then genetically engineered nsp2TF protein knockout viruses.

"These knockout viruses could be potentially used to develop vaccines," Fang said. "Additionally, this novel mechanism of gene expression may also be used by other viruses or in cellular gene expression."

Fang joined Kansas State University in 2013.

"Dr. Fang is recognized as one of the top PRRS experts in the world," said M.M. Chengappa, university distinguished professor of microbiology and head of the department of diagnostic medicine and pathobiology. "We are so fortunate to have faculty of her caliber and stature at Kansas State University. She brings enormous depth and breadth to our research and graduate training program."


'/>"/>

Contact: Ying Fang
yfang@k-state.edu
785-532-4452
Kansas State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
4. UNH researchers find African farmers need better climate change data to improve farming practices
5. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
6. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
7. Researchers print live cells with a standard inkjet printer
8. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
9. Researchers reveal how a single gene mutation leads to uncontrolled obesity
10. Researchers discover novel therapy for Crohns disease
11. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers find a new gene expression mechanism of PRRS virus
(Date:3/19/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... mobile commerce market, announces its biometric payment technology, the Wocket® ... this week on Washington DC,s Fox ... segment "The Next Great Thing", host Laura Evans ... and ,a really big breakthrough in mobile payment.,  ...
(Date:3/16/2015)... 2015 Between 16 and ... groundbreaking innovations in biometric identification at the CeBIT ...      (Photo: http://photos.prnewswire.com/prnh/20150316/735333 ) ... well at the forefront: the company,s all new ... Germany . BiometricGate is the ...
(Date:3/11/2015)... Mar. 11, 2015 Research and Markets ... "Access Control Market by Product, Application & By ... report to their offering. , This report ... reach $10.4 billion by 2020, with an estimated CAGR ... covers the products types such as contact cards & ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2
... Molecular biologists, developmental biologists and computer scientists at the ... cracking the code for how gene expression is controlled. ... in January 2006. , A genome milestone was reached ... completed. This has been followed by complete chemical read-outs ...
... cluster of 45 genes coding for antibacterial drug ... cause of hospital-acquired infections worldwide. The study ... , "We expected to find resistance genes," said ... and Genomic Information Laboratory at France's National Center ...
... Thanks to this flexibility--the arm is said to ... freedom"--the octopus is able to generate a vast ... human arm. Nonetheless, despite the huge evolutionary gap ... the octopus arm acts much like a three-jointed ...
Cached Biology News:Cracking the genetic code for control of gene expression 2Supersized 'island' of resistance genes discovered in an infectious bacterium 2How the octopus forms an elbow 2
(Date:3/26/2015)... 26, 2015 PRC Clinical, a Silicon-Valley ... several management and executive appointments effective immediately. , Mike ... (CFO) and member of the Board of Directors. Daniel ... and Sue Dowden will assume the position of Senior ... Chief Operations Officer (COO), has been appointed to the ...
(Date:3/26/2015)... 26, 2015 Neogen Corporation (NASDAQ: NEOG ... third quarter of fiscal 2015, which ended Feb. 28, ... year,s $6,575,000. Earnings per share in the current quarter ... year-to-date net income increased 17% over prior year to ... $0.56 per share, for the same period a year ...
(Date:3/26/2015)... 26, 2015 WriteResult, a premier provider ... from Yale University’s School of Public Health and New ... during a 4 month-long project. The goal of the ... income families with free access to fresh produce and ... health concerns like high blood pressure, diabetes and weight ...
(Date:3/25/2015)... UK (PRWEB) March 25, 2015 ... uptake of smartphones have fuelled social media growth, ... being currently engaged in social networking. Insurance companies ... to communicate with clients and promote a diversity ... globe over are increasingly exploiting social networking services ...
Breaking Biology Technology:PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 2PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 3Neogen reports 13% increase in net income 2Neogen reports 13% increase in net income 3Neogen reports 13% increase in net income 4Neogen reports 13% increase in net income 5Neogen reports 13% increase in net income 6Neogen reports 13% increase in net income 7Neogen reports 13% increase in net income 8Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 2Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 3Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3
... , ANNAPOLIS, Md., Dec. 8 ... company specializing in the development and commercialization of medical countermeasures ... hold a conference call at 9:00 a.m. Eastern Time, on ... recombinant protective antigen (rPA) anthrax vaccine program. The dial-in ...
... , CORALVILLE, Iowa, Dec. 8 Vivakor, ... how shareholders of record on December 1, 2009 will receive ... that was previously approved by Vivakor,s Board of Directors. HealthAmerica ... 84% of the outstanding common shares on the record date. ...
... , SAN DIEGO, Dec. 8 ... announced today they have licensed their Target Informatics Platform (TIP) ... Toxicological Research (NCTR). , Under the terms of the license, ... TIP structural knowledgebase via onlineTIP as well ...
Cached Biology Technology:PharmAthene Announces Updated Time for Conference Call to Review BARDA rPA Decision 2Vivakor Announces Mechanics of Dividend Distribution 2Vivakor Announces Mechanics of Dividend Distribution 3Eidogen-Sertanty Licenses TIP to the FDA 2
... containing Vaginal Keratinocyte Progenitors, Rabbit, and media. ... and 10% DMSO at passage 25 (approx), ... medium.This cell culture is supplied as a ... an additional 6 months of continuous growth ...
... use spatulas have been designed to save ... for those interested in eliminating the recycling ... spatula is individually packaged, RNase/DNase free, non-pyrogenic ... a new product number, created to easily ...
... high-density functional protein microarray is the first ... proteinprotein interactions on a proteome scale. The ... reading frames (ORFs) expressed as 5'-GST fusions, ... 1 inch x 3 inch nitrocellulose-coated slide. ...
... is a compact, versatile system that simultaneously ... or 24-well microplates into a solid filter ... scintillation and gamma counter. The FilterMate is ... applications such as cell proliferation, receptor binding, ...
Biology Products: