Navigation Links
Researchers discover that coevolution between humans and bacteria reduces gastric cancer risk
Date:1/15/2014

Hanover, NH - Research carried out in two distinct communities in Colombia illustrates how coevolution between humans and bacteria can affect a person's risk of disease. Working with colleagues in Columbia and the U.S., Scott Williams, PhD, a professor of genetics at the Geisel School of Medicine at Dartmouth, and his graduate student Nuri Kodaman discovered that the risk of developing gastric cancer depends heavily on both the ancestry of the person and the ancestry of Helicobacter pylori with which that person is infected. About half of the world's population is infected with H. pylori. The microbe usually only causes minor gastric inflammation, but it is also the primary cause of gastric cancer, which is the second-leading cause of death by cancer worldwide.

Williams' research team studied 233 people from two populations in Colombia, one located in the mountain village of Tuquerres and the other in the coastal village of Tumaco. Rates of H. pylori infection in the two communities are similar (about 90%), but the rate of gastric cancer is about 25 times higher in the mountain community. The researchers classified the ancestry of the people in both villages and of the H. pylori in each area. In the coastal village, the human population was primarily of African descent. The dominant component of the H. pylori also came from Africa. In the mountain village, the people were largely Amerindian and had very little African ancestry, and the H. pylori was predominantly derived from Europe.

The researchers examined the connections between human ancestry, the strains of H. pylori, and the severity of gastric disease and made several important findings: First, among both populations, people of European or Amerindian descent were at greater risk of developing more severe lesions than were people of African descent. Second, in the mountain community, where most people were of Amerindian or
'/>"/>

Contact: Derik Hertel
derik.hertel@dartmouth.edu
603-650-1211
The Geisel School of Medicine at Dartmouth
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers identify key components linking circadian rhythms and cell division cycles
2. Microbes swap for tiny goods in minuscule markets, researchers find
3. New discovery could stimulate plant growth and increase crop yields, researchers say
4. White House lauds ONR-funded researchers for early success
5. KIT researchers develop artificial bone marrow
6. Researchers pursuing arthritis protein
7. Researchers discover a tumor suppressor gene in a very aggressive lung cancer
8. Researchers unveil rich world of fish biofluorescence
9. Researchers propose alternative way to allocate science funding
10. New organization brings together top researchers to sequence the genomes of invertebrates
11. Plan to delist gray wolf endangers other threatened species, researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover that coevolution between humans and bacteria reduces gastric cancer risk
(Date:9/23/2014)... organisms, including humans, have parasitic DNA fragments called "jumping ... instructions in the process. And that phenomenon can result ... the University of Rochester now report that the "jumping ... when a multi-function protein stops keeping them in check ... In a study published today in Nature Communications ...
(Date:9/22/2014)... Chicago have shown that after a long stay in ... pathogenic microbe species remain behind in patients, intestines. The ... can become deadly when provoked by conditions that mimic ... published in mBio , the online open-access journal ... better monitoring and treatment of ICU patients who can ...
(Date:9/22/2014)... September 23, 2014 A new American Cancer ... Nutrition Assistance Program (SNAP), previously known as the ... compared with income eligible non-participants. The authors say ... aimed at enhancing the dietary quality of SNAP ... low-income individuals and households with the resources to ...
Breaking Biology News(10 mins):A multi-function protein is key to stopping genomic parasites from 'jumping' 2Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 2Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 3Federal food program puts food on the table, but dietary quality could be improved 2
... Santa Barbara have developed new methods for studying how environmental ... spatial and temporal scales. The scientists merged data collected ... canopies taken by the Landsat 5 Thematic Mapper. The findings ... issue of Marine Ecology Progress Series. In ...
... of State Foresters released the first phase of the Southern ... areas forest managers will focus on to maintain southern forests ... urbanization, bioenergy use, weather patterns, land ownership changes and invasive ... 2010 and 2060. About 23 million acres of forest ...
... is available in Spanish . The ... Ikerbasque, is participating in the AWIN -Animal Welfare Indicators project. ... international experts in animal welfare from 11 centres. The group ... University of Edinburgh on the 10 and 11 of May, ...
Cached Biology News:UCSB scientists track environmental influences on giant kelp with help from satellite data 2UCSB scientists track environmental influences on giant kelp with help from satellite data 3Forest Service unveils first comprehensive forecast on southern forests 2Forest Service unveils first comprehensive forecast on southern forests 3Neiker-Tecnalia participates in a European project for improving the welfare of farm animals 2Neiker-Tecnalia participates in a European project for improving the welfare of farm animals 3
(Date:9/22/2014)... 22, 2014 This is a professional ... M-Phenylenediamine (mPDA) industry in Global and China. The ... definitions, applications and industry chain structure. Global market analysis ... focus on history, developments, trends and competitive landscape of ... situation is also offered. , The report also focuses ...
(Date:9/22/2014)... Research and Markets has announced ... Cellulose Industry Report 2014" report to their offering. ... Industry Report 2014 is a professional and in-depth study ... industry with a focus on the Chinese situation. ... industry including definitions, classifications, applications and industry chain structure. ...
(Date:9/22/2014)...  WIRB-Copernicus Group (WCG), the world,s largest provider ... research, announced today that its Western Institutional Review ... the Association for the Accreditation of Human Research ... for clinical research participants. WCG Chairman ... commented, "It is of utmost importance to WCG ...
(Date:9/21/2014)... Switzerland have succeeded in observing the "forbidden" infrared ... time. These extremely weak spectra offer perspectives for ... also contribute to the development of molecular clocks ... the scientific journal Nature Physics . , ... and light, is probably the most important method ...
Breaking Biology Technology:m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 2m-Phenylenediamine Industry: mPDA Global & China Trend Analysis Now Available at ReportsnReports.com 3Global and Chinese Microcrystalline Cellulose Industry Report 2014 2Western IRB (WIRB) Awarded AAHRPP Reaccreditation 2Uncovering the forbidden side of molecules 2
... to grow over 23% per year due to new cellulite ... Millennium Research Group, WALTHAM, Mass., April 9, 2008 ... Devices 2008 report,the cellulite reduction device market was worth almost ... next five years, rising to over,$215 million by 2012. Growth ...
... Cytopia Limited,(ASX: CYT) today announced that it ... American Association for Cancer Research Annual Meeting being ... 17,000,participants from around the world to discuss new ... titled "A Novel JAK2 inhibitor for the treatment ...
... 2008 Dendreon Corporation,(Nasdaq: DNDN ) today ... direct offering of 8.0 million shares of its ... million shares of its common,stock. Net proceeds received ... LLC served as sole placement agent for the ...
Cached Biology Technology:Say Good-Bye to Cellulite 2Dendreon Announces Closing of Registered Direct Offering 2
... PS603. Immunogen: Synthetic phosphopeptide ... the phosphorylated Ser603 residue of ... Specific for synapsin I when ... Reactivity: Rat (positive control: ...
CMRL Medium-1066 (1X) liquid...
... 11(R)-HETE is biosynthesized by the ... purpuratus, and the fresh water hydra, ... 11(R)-HETE relates to oocyte maturation and ... species.11(R)-HETE is also produced when aspirin-treated ...
... PhosphatidylEthanolamine-Binding Protein (PEBP) does not share ... inhibitors. PEBP is expressed in ... ovary, muscle, and stomach. One ... is exerting inhibitory activity against several ...
Biology Products: