Navigation Links
Researchers discover novel therapy for Crohn's disease
Date:3/19/2012

The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) research team at Virginia Tech has discovered important new information on the efficacy of conjugated linoleic acid (CLA) in treating Crohn's disease, a form of inflammatory bowel disease (IBD). CLA is a naturally occurring acid found in meat and dairy products known for its anti-cancer and immune modulatory properties.

In collaboration with the Division of Gastroenterology and Hepathology at University of North Carolina School of Medicine and the Wake Forest Medical Center, researchers found that Crohn's patients who took supplementary CLA showed noticeable improvement. "In our recent open label study of CLA as a supplement in study subjects with mild to moderate CD there was a marked improvement in disease activity and quality of life in 50% of the subjects. CLA was well tolerated by all of the study subjects. These findings are very encouraging and will need to be verified in a randomized controlled trial," said Professor Kim L. Isaacs, a Professor of Gastroenterology at the University of North Carolina at Chapel Hill.

The two main manifestations of IBDCrohn's and ulcerative colitisafflict over 1.4 million people in the United States. Symptoms include abdominal cramping, fever, fatigue, loss of appetite, skin and mouth ulcers, and diarrhea or constipation. In addition, the risk of developing colorectal cancer increases by about one percent yearly in IBD patients. Currently, there is no cure for Crohn's disease and the exact causes of it aren't fully understood.

CLA affords those afflicted with mild to moderate IBD an effective treatment without the unwanted side effects of many synthetic drugs. "Furthermore, we have demonstrated that probiotic bacteria can produce CLA locally and suppress colitis. Therefore, CLA can be administered directly in capsules or indirectly through CLA-producing probiotic bacteria," said Dr. Raquel Hontecillas, an Assistant Pro
'/>"/>

Contact: Tiffany Trent
ttrebt@vbi.vt.edu
540-231-6822
Virginia Tech
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers reveal how a single gene mutation leads to uncontrolled obesity
2. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
3. Researchers print live cells with a standard inkjet printer
4. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
5. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
6. UNH researchers find African farmers need better climate change data to improve farming practices
7. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
8. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
9. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
10. University of Tennessee researchers invent device to rapidly detect infectious disease
11. Researchers find safer way to use common but potentially dangerous medication
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers discover novel therapy for Crohn's disease
(Date:11/15/2014)... -- While we may still be a few years away from ... to gain instant access to all that ailed his patients, ... tablets for monitoring and measuring our health are cropping up ... a tad Orwellian to some, but a new survey suggests ... opportunities into their healthcare regime. These are some ...
(Date:11/10/2014)... detergent pods began appearing on U.S. store shelves in ... numbers ever since. The small packets can be tossed ... out a liquid or powder. The convenience, though, has ... study from researchers at Nationwide Children,s Hospital found that ... reports of 17,230 children younger than 6 years of ...
(Date:11/7/2014)... Florida , November 6, 2014 ... authentication for better mobile security revolutionizing online transactions.  Companies in ... Alibaba Holdings Ltd. (NYSE: BABA ), Google Inc. ... MSFT ), eBay Inc. (NASDAQ: EBAY ) and ... NXTD and NXTDW), a biometric authentication company focused ...
Breaking Biology News(10 mins):Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4Study finds laundry detergent pods, serious poisoning risk for children 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6
... $50 billion in manufactured goods last year, according to ... $2.6 trillion. By 2011, over $15 billion in nano-enabled ... $3 billion in 2006. And industry experts project that ... consumer food products by 2010. Yet, ...
... Artificial teeth and crowns made of ceramic material are ... but that may change because of a technique that ... Oak Ridge National Laboratorys Materials Science and Technology Division has ... ceramics alters the surface structure. Nowadays, cracks begin at the ...
... Brussels & Leuven, Belgium As the most common ... carries enormous implications for our ageing society. It is ... peptide (A -peptide) protofibrils. Until now, the conditions under ... to the disease remained unknown. VIB researchers have now ...
Cached Biology News:FDLI, PEN co-sponsor major conference on nanotechnology 2FDLI, PEN co-sponsor major conference on nanotechnology 3Story tips from the Department of Energy's Oak Ridge National Laboratory, December 2007 2Story tips from the Department of Energy's Oak Ridge National Laboratory, December 2007 3Lipids in the brain an important factor for Alzheimer's disease? 2
(Date:11/24/2014)... Calif. , Nov. 24, 2014   Veracyte, Inc. ... Bonnie H. Anderson , president and chief executive officer, will ... 26 th Annual Healthcare Conference on Tuesday, December 2, ... . The live audio webcast and subsequent ... http://investor.veracyte.com . Please connect to the website at least 15 ...
(Date:11/24/2014)... 2014  Spherix Incorporated (Nasdaq: SPEX ... fostering and monetization of intellectual property, today provided ...  Case No. 3:13-cv-03494-M and  Spherix v. Uniden Corporation ... the United States District Court for the Northern ... On November 21, 2014 the Markman ...
(Date:11/22/2014)... (PRWEB) November 21, 2014 Prominent ... investors will gather on December 3rd at Genetic ... Conferences series. GeneticRx will take place at the ... School and will discuss the present and future ... exon skipping, and gene editing—as well as the ...
(Date:11/22/2014)... Rapids, MI (PRWEB) November 22, 2014 ... opportunity to simulate the proper management of life-like ... and test lung devices . Grand Rapids-based, Michigan ... plans to donate two of the respiratory simulation ... to $15,000 each. Grand Valley and Muskegon Community ...
Breaking Biology Technology:Veracyte to Present at the Piper Jaffray 26th Annual Healthcare Conference 2Markman Hearing Held as Scheduled in VTech and Uniden Cases 2Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3
... Sept. 16 Metamark Genetics, Inc., a privately held ... optimize cancer care, announced today the appointment ... Dr. Blume-Jensen joins Metamark with over 20 ... discovery. From 2001 to 2008 Dr. Blume-Jensen was department ...
... Sept. 15 CryoLife, Inc. (NYSE: ... processing company, announced today that it will participate in the ... in New York City. D. Ashley Lee, executive ... CryoLife, Inc., will present a corporate overview on Tuesday, September ...
... 14, 2010 -- As industries and consumers increasingly seek ... Department of Energy,s Oak Ridge National Laboratory is providing ... A research team led by ORNL,s Nina Balke, ... type of scanning probe microscopy called electrochemical strain microscopy ...
Cached Biology Technology:Metamark Genetics, Inc. Announces New Chief Scientific Officer 2CryoLife to Present at UBS Global Life Sciences Conference 2ORNL scientists reveal battery behavior at the nanoscale 2
RABBIT ANTI HALOPERIDOL...
Form: Ready to use Applications: Western Blot, ELISA...
... Analyzer for General Chemistries, Specialty Chemistries, QC, Reagent Development, Pharmaceutical Development, Physician Owned Labs, Drugs ... user-selectable wavelengths. ... ... ...
2,4,6, Trinitrophenyl hapten is conjugated to lipopolysaccharide (LPS)....
Biology Products: