Date:2/24/2013

nd 300 of such genes, that is to say, those that would have the region holding regulatory signals removed. This is precisely the region where microRNAs small molecules regulating the translation of this RNA to protein bind. "Many antitumor therapies attempt to interfere with microRNA binding, but we have now revealed that CPEB proteins remove these regions beforehand. The pharmaceutical companies that are developing anti- microRNA compounds will be able to predict whether their targets are suitable approaches or not", explains the scientist.

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Contact: Snia Armengou armengou@irbbarcelona.org 34-934-037-255 Institute for Research in Biomedicine (IRB Barcelona) Source:Eurekalert

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