Navigation Links
Researcher tests promising drug on those with Down syndrome
Date:8/2/2011

AURORA, Colo. (Aug. 1, 2011) A University of Colorado School of Medicine scientist is completing a major clinical trial on a drug that could boost cognitive function in those with Down syndrome, significantly improving their quality of life and representing a potential milestone in research on this genetic condition.

"We are hoping to enhance memory and learning in those with Down syndrome," said Alberto Costa, MD, PhD, an associate professor of medicine and the neuroscientist leading the effort. "We have been studying this drug for three years and are now ready to analyze the data on our trial. Our team at the University of Colorado and Children's Hospital Colorado expects to have the results in the next two or three months."

Costa, whose work was chronicled in last Sunday's New York Times Magazine, is testing the drug memantine, currently used to relieve symptoms of Alzheimer's disease, in 39 people with Down syndrome. About half received the drug and the others a placebo. In 2007, Costa demonstrated that memantine could improve memory function in mice with Down syndrome.

And now, for the first time, he is taking a drug effective in the treatment of learning and memory deficits in mice with Down syndrome and applying it to humans, a move described by the New York Times as "a milestone in the history of Down syndrome research."

Costa is no disinterested researcher. His 16-year-old daughter Tyche named for the Greek goddess of Fortune - has Down syndrome. Like others with the condition, she faces the specter of a steady decline in mental functioning as she gets older and a roughly 20 percent chance of getting Alzheimer's in her 50's. After that diagnosis, death is often just five years away.

"I feel I am racing the clock to find something that will at least keep her functioning at the level she is at now," Costa said. "As they age, parts of their brain will shrink and their functions will diminish."

Costa
'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
303-315-6374
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related biology news :

1. U of M researchers use improved imaging technique; discover a better approach to diagnosing epilepsy
2. RUB researchers decipher the molecular basis of blue-green algae
3. Researchers discover the mechanism that determines cell position in the intestinal epithelium
4. Caltech researchers increase the potency of HIV-battling proteins
5. Researchers tap yeasts as source of green surfactants
6. Lawson researchers take control of cancer
7. U researchers look to dogs to better understand intricacies of bone cancer
8. Penn researchers help graft olfactory receptors onto nanotubes
9. U of M researchers may have discovered key to help women fight infections during pregnancy
10. Behavior 2011 to draw global contingent of more than 1,100 animal researchers to IU next week
11. U of M researchers discover gene required to maintain male sex throughout life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... and POINT ROBERTS, Washington , January 20, ... leading sectors including technology and tech stocks, releases video from ... master pickpocket and security consultant Apollo Robbins . ... talks about the Wocket™ biometric smart wallet, a product of ...
(Date:1/22/2015)... January 22, 2015 , ... The European Patent Office to present a video retrospective ... nominations to be featured: Christofer Toumazou and Sophie ... finalists and winners of the Award   Starting on ...
(Date:1/22/2015)... Jan. 22, 2015   EyeLock, Inc. , a market leader ... Steve Gerber to the new role of Senior ... for leading development of mobile platforms and wearable solutions for ... and innovation in the semiconductor industry to his role at ...
Breaking Biology News(10 mins):Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... most biofuels crops, including corn, rapeseed and wheat, have ... suggesting many countries need to reset their expectations of ... according to a study led by Matt Johnston and ... for Environmental Studies and Jon Foley of University of ...
... new application of photoacoustic tomography (PAT) is worth its ... For the first time, Lihong Wang, Ph.D., Gene ... Engineering, with a joint appointment in Radiology, and Younan ... with a joint appointment in chemistry in Arts & ...
... the University of Pittsburgh School of Medicine have successfully ... replicate robustly in a living animal, as well as ... models and methods for studying diabetes, but also opens ... scientists thought that these important pancreatic cells could not ...
Cached Biology News:Nations that sow food crops for biofuels may reap less than previously thought 2Nations that sow food crops for biofuels may reap less than previously thought 3Novel technique changes lymph node biopsy, reduces radiation exposure 2Human beta cells can be easily induced to replicate, according to study in Diabetes 2
(Date:1/23/2015)... Portal Solutions , a technology consulting ... Microsoft Office 365 and SharePoint platforms , today announces its ... being one of the region’s fastest-growing mid-sized companies based on ... , “To be recognized a second year in a row ...
(Date:1/22/2015)... GEA Niro Soavi the leader in high ... PandaPLUS 2000, which is ideal for new applications for ... disruption . This compact laboratory homogenizer is the perfect ... food additives and ingredients as well as for the ...
(Date:1/22/2015)... Johnston, RI (PRWEB) January 22, 2015 ... State , The growing team of brand-neutral, independent consultants, ... CIO Philip Rogers explained that over the years, his ... including , Moroso, Town of Plainfield, as well as ...
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently was ... Pre-Conference seminar on probiotics in San Diego, CA. , ... conference for health care professionals. This year’s pre-conference seminar was ... in health. Dr. Leyer spoke about the emerging topics and ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... and GridGain System partnered up in delivering industry first dedicated solution ... The integration between GridGain,s Open Cloud Platform and Inventigo,s FastXML product ... near real-time fashion. , ... San Francisco, CA (PRWEB) ...
... and Endpoints in both Chemotherapy Naive and Post-Chemotherapy Patients ... Cancers Symposium -- Medivation to Host Conference Call and ... p.m. Eastern Time - SAN FRANCISCO, Feb. 25 ... the presentation of new efficacy and safety data from ...
... /PRNewswire/ - How does a Science Cluster work? Vineland ... with its model for the future. , "Vineland will ... Canada, industry will steer the direction and government will ... Research and Innovation Centre. "And as we execute on ...
Cached Biology Technology:Inventigo and GridGain Systems Team Up on Delivering Cloud-Enabled High Performance XML Processing 2Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients 2Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients 3Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients 4Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients 5Vineland Enables Industries' Efforts to Build Agri-Science Research Cluster 2
...
... Dissociation Buffers are membrane-filtered isotonic and ... agents and cell-conditioning agents in either ... solution or Ca2+- and Mg2+-free ... mammalian cells from support substrates and ...
... Buffers are membrane-filtered isotonic and enzyme-free ... and cell-conditioning agents in either Ca2+- ... or Ca2+- and Mg2+-free phosphate-buffered ... cells from support substrates and each ...
... Antibody Modification Services ... including antibody labeling and antibody fragmentation. ... provides signals for visualization and quantitation ... assays, it is preferable to use ...
Biology Products: