Navigation Links
Research team honored for innovative science to advance cancer research
Date:2/7/2011

ORLANDO, Fla. The Fifth Annual AACR Team Science Award will be given to a team of internationally renowned molecular biologists, epidemiologists, biostatisticians and clinicians from Fred Hutchinson Cancer Research Center and University of Washington who have worked together on human papillomavirus (HPV) for more than 20 years.

This award recognizes an outstanding interdisciplinary research team for its innovative and meritorious science that has advanced or will likely advance cancer research, detection, diagnosis, prevention or treatment.

"This team's work exemplifies how cancer research can dramatically impact public health," said Margaret Foti, Ph.D., M.D. (h.c.), chief executive officer of the AACR. "The researchers' long-term collaborations in basic science, epidemiology and clinical research played a vital role in increasing our understanding of HPV and developing the HPV vaccine, which has the potential to prevent more than half a million HPV-associated cancers each year, worldwide."

By combining molecular assays to detect and characterize HPV infections with epidemiologic approaches, the 12-member team, led by Denise Galloway, Ph.D., head of the Cancer Biology Program at Fred Hutchinson Cancer Research Center, showed that HPVs are associated with nearly all genital-tract cancers and with a significant proportion of head and neck cancers. They conducted what is among the largest case-control studies of HPV-associated cancers and revealed that a variety of exposures notably a high number of sexual partners and early age at first intercourse were common across most of the anogenital cancer sites. The researchers also identified factors beyond sexual activity, such as immunosuppression, that contributed to HPV infection.

The team played a pivotal role in making virus-like particle-based vaccines a reality, from the early basic science work to the epidemiology, to the proof-of-principle clinical trial that showed that a monovalent HPV 16 vaccine protected against HPV 16 infection and disease.

"Our team is thrilled to receive such a wonderful honor," said Galloway. "Credit is due to the entire HPV research community the investigators, research fellows, students and study participants who helped to make our efforts a reality. We are delighted to have been able to contribute to an international team of scientists that collectively moved the field from a state in which the etiology of cervical cancer was not known, to now have vaccines to prevent HPV."

Additionally, Galloway and colleagues developed and tested new strategies for early detection and treatment of HPV-related cancers. Their clinical studies demonstrated the cost-effectiveness of using HPV DNA testing of clinician-collected cervical samples or self-collected vaginal samples in screening programs as well as the potential for using novel biomarkers to more accurately diagnose HPV-related cancers and precancerous lesions.

The AACR Team Science Award, generously supported by a grant from Eli Lilly and Company, is given to affect change within the traditional cancer research culture by recognizing those individuals and institutions that value and foster interdisciplinary team science. The team will collectively receive a $50,000 prize and will be cited for its leadership role in fostering team science. Honorees include (in alphabetical order):

  • Janet Daling, Ph.D., member emeritus, public health sciences division, Fred Hutchinson Cancer Research Center, and professor emeritus, department of epidemiology, University of Washington;

  • Denise Galloway, Ph.D., member, human biology and public health sciences divisions, Fred Hutchinson Cancer Research Center, and research professor, departments of microbiology and pathology, University of Washington;

  • James Hughes, Ph.D., professor, department of biostatistics, University of Washington;

  • Nancy Kiviat, M.D., professor, department of pathology, University of Washington;

  • Laura Koutsky, Ph.D., professor, department of epidemiology, University of Washington;

  • Margaret Madeleine, Ph.D., assistant member, public health sciences division, Fred Hutchinson Cancer Research Center, and assistant professor, department of epidemiology, University of Washington;

  • Constance Mao, M.D., assistant professor, department of obstetrics and gynecology, University of Washington, and director, Harborview Women's Colposcopy Clinic;

  • Barbara McKnight, Ph.D., member, public health sciences division, Fred Hutchinson Cancer Research Center, and professor, department of biostatistics, University of Washington;

  • Peggy Porter, M.D., member, human biology and public health sciences divisions, Fred Hutchinson Cancer Research Center, and professor, department of pathology, University of Washington;

  • Stephen Schwartz, Ph.D., member, public health sciences division, Fred Hutchinson Cancer Research Center, and professor, department of epidemiology, University of Washington;

  • Hisham Tamimi, M.D., professor, department of obstetrics and gynecology, University of Washington; and,

  • Long-fu Xi, Ph.D., research associate professor, department of pathology, University of Washington.

The AACR Team Science Award will be presented at the AACR 102nd Annual Meeting 2011 opening ceremony on Sunday, April 3, in the Orange County Convention Center, in Orlando, Fla.


'/>"/>

Contact: Michele Sharp
Michele.Sharp@aacr.org
267-646-0622
American Association for Cancer Research
Source:Eurekalert

Related biology news :

1. Research proves new soybean meal sources are good fish meal alternatives
2. Springer and the French National Institute for Agricultural Research INRA team up
3. Research links 29 genome regions with common form of inflammatory bowel disease
4. Just in time for Valentines Day: UNC researchers identify a gene critical for heart function
5. Johns Hopkins researchers capture jumping genes
6. The brain knows what the nose smells, but how? Stanford researchers trace the answer
7. Scientific research reveals brain alterations linking omega 3 deficit with depression
8. Arctic fisheries catches 75 times higher than previous reports: UBC research
9. Cornell researchers find a strong community protects adolescents from risky health behavior
10. Scientists urge new research policies in wake of Gulf disaster
11. First new C. difficile drug in a generation superior to existing treatments: Researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology: