Navigation Links
Research shows how 'Mallard' dye fills need for speed
Date:2/14/2013

Scientists at the University of York have developed a new medical tool which could help surgeons carrying out complex procedures in the operating theatre.

Researchers have developed a dye which provides a quick and accurate method of checking heparin levels in the blood. Heparin is an important anti-coagulant which has a significant role in major surgery. The scientists in the Department of Chemistry at York have used inspiration from biological systems to allow the dye to bind heparin even in highly competitive human serum.

In the laboratory, they have modified existing dyes which previously could not bind with heparin successfully under these challenging conditions. The modified dye, which has excellent sensing capacity for heparin pinpoints the anti-coagulant's level in human serum and has the potential to work more quickly than existing clinical methods for doing this.

The research, which was funded by the Biotechnology and Biological Sciences Research Council, is published in the Journal of the American Chemical Society.

Because the dye can rapidly detect heparin levels, the scientists have named it 'Mallard Blue'. It is the same shade as the livery of the A4 Pacific Mallard, which holds the world speed record for a steam locomotive, and is now preserved at the National Railway Museum in York.

Professor Dave Smith, of the Department of Chemistry at York who led the research said: "Our new dye allows the quantification of heparin in serum at clinically relevant levels and is the best in class for this application in terms of its ability to bind heparin strongly under really competitive biological conditions, and may improve on the currently used systems.

"We have named the dye 'Mallard Blue', after the record-breaking steam train, 'Mallard' which is housed in the railway museum here at York. Our dye is the same colour as the locomotive, and we believe it is similarly ground-breaking in its performance."

The York researc
'/>"/>

Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers make racehorses fertile
2. Canadas aquatic ecosystems research gets boost from NSERC
3. FASEB joins President Obama in urging Congress to sustain investments in research and innovation
4. World first for fly research
5. Research improving breast cancer treatment by targeting tumor initiating cells
6. Explosive breakthrough in research on molecular recognition
7. Cities can reduce greenhouse gas emissions by 70 percent, says U of T researcher
8. USC researchers find possible genetic clues to organ development, birth defects
9. Researchers discover Achilles heel for lymphoid leukemia
10. Researchers find Asian needle ants displacing other aggressive invaders
11. NIH grant funds Boston College research into illnesses afflicting people living with HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... , Mar. 19, 2015 Research and Markets ... "Iris Biometrics - Global Strategic Business Report" report to ... for Iris Biometrics in US$ Thousands. The report provides separate ... Japan , Europe , ... , and Latin America . ...
(Date:3/17/2015)... March 17, 2015 Emotient, the leader ... today announced general availability of Emotient Analytics ... the analysis of facial expressions. The system analyzes ... content, products and services. It delivers audience response ... sentiment - as derived from facial evidence of ...
(Date:3/12/2015)... March 12, 2015 The mascots of the ... Hospital, part of Wake Forest Baptist Medical Center. They ... the 2015 ACC Men,s Basketball Tournament. Young patients enjoyed ... and getting their autographs. Brenner Children,s Hospital ... is the only children,s hospital in northwest ...
Breaking Biology News(10 mins):Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4
... is known to be particularly prone to global warming ... and other greenhouse gases. Now, a University of Utah ... the far north: the Arctic's well-known haze ?made of ... making them better able to trap heat. , The ...
... emissions of carbon dioxide from fossil fuel burning ... organisms, including corals, that secrete skeletal structures and ... summarizes the known effects of increased atmospheric carbon ... and recommends future research for determining the extent ...
... apparently transform into any kind of cell in the body, ... - even when they are outside of the body in ... an animal model of embryonic stem cell development, researchers with ... the most fundamental questions in science - how does a ...
Cached Biology News:Pollutant haze heats the Arctic 2Pollutant haze heats the Arctic 3Pollutant haze heats the Arctic 4Report warns about carbon dioxide threats to marine life 2Report warns about carbon dioxide threats to marine life 3Medium is the message for stem cells in search of identities 2Medium is the message for stem cells in search of identities 3
(Date:3/30/2015)... , March 30, 2015 /CNW/ - A new national ... the salaries and demographic profiles of new graduates entering ... Door – Building Careers for New Grads in Biotech," ... Research-Based Pharmaceutical Companies (Rx&D) and features data collected ... Focus wage subsidy program from 2013 to 2015. ...
(Date:3/30/2015)... Immunocore Limited, a world-leading ... cancer, viral infections and autoimmune disease, today announced ... , the Regius Professor of Medicine at Oxford ... Strategic Coordination of Health Research, to its Board ... (Photo: http://photos.prnewswire.com/prnh/20150330/736483 ) , ...
(Date:3/29/2015)... , March 29, 2015  Caris Life ... in which Caris Molecular Intelligence®, the company,s panomic, ... and differences between several rare and difficult to ... that have the potential to improve patient outcomes. ... B at the Society of Gynecologic Oncology (SGO) ...
(Date:3/27/2015)... Earlier this year, the Capillus272Pro™ received ... in adult men and women with androgenic alopecia (AGA) ... of IIa-V and Fitzpatrick Classification of Skin phototypes I-IV. ... over-promise and under-deliver, FDA Clearance underscores the safety and ... more than 80 million men and women who suffer ...
Breaking Biology Technology:New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 2New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 3New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 4Immunocore Appoints Professor Sir John Bell to its Board of Directors 2Immunocore Appoints Professor Sir John Bell to its Board of Directors 3Immunocore Appoints Professor Sir John Bell to its Board of Directors 4Immunocore Appoints Professor Sir John Bell to its Board of Directors 5Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 2Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 3Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 4Dr. Robert Leonard Applauds FDA Clearance of Capillus272Pro™ Hair Loss Laser Cap 2
... life sciences provider Promega broke ground on Wednesday for a ... located next to the existing Promega offices. , ,The $22 ... Cheryl Parkway and Fish Hatchery Road, 62,000 of which will ... retail space. The expansion will provide Promega with further manufacturing ...
... Medical College of Wisconsin has received a five-year, $1 ... anesthetics protect the human heart against injury from interruptions ... The college also has received a grant for the ... Ph.D., professor and vice chairman of anesthesiology and professor ...
... -- Cingular Wireless will invest more than $300 ... Wisconsin -- including turning on-air 110 new cell sites, ... will spend $6.2 billion to enhance and expand its ... year, Cingular put into service 22 cell ...
Cached Biology Technology:
Polyclonal Antibody to CLAN...
Goat polyclonal to MLH3 ( Abpromise for all tested applications). entrezGeneID: 27030 SwissProtID: Q9UHC1...
Rabbit polyclonal to NMDAR1 e/f/g/h ( Abpromise for all tested applications)....
Biotin anti-mouse Ly-49C/F/I/H...
Biology Products: