Navigation Links
Research shows how 'Mallard' dye fills need for speed
Date:2/14/2013

Scientists at the University of York have developed a new medical tool which could help surgeons carrying out complex procedures in the operating theatre.

Researchers have developed a dye which provides a quick and accurate method of checking heparin levels in the blood. Heparin is an important anti-coagulant which has a significant role in major surgery. The scientists in the Department of Chemistry at York have used inspiration from biological systems to allow the dye to bind heparin even in highly competitive human serum.

In the laboratory, they have modified existing dyes which previously could not bind with heparin successfully under these challenging conditions. The modified dye, which has excellent sensing capacity for heparin pinpoints the anti-coagulant's level in human serum and has the potential to work more quickly than existing clinical methods for doing this.

The research, which was funded by the Biotechnology and Biological Sciences Research Council, is published in the Journal of the American Chemical Society.

Because the dye can rapidly detect heparin levels, the scientists have named it 'Mallard Blue'. It is the same shade as the livery of the A4 Pacific Mallard, which holds the world speed record for a steam locomotive, and is now preserved at the National Railway Museum in York.

Professor Dave Smith, of the Department of Chemistry at York who led the research said: "Our new dye allows the quantification of heparin in serum at clinically relevant levels and is the best in class for this application in terms of its ability to bind heparin strongly under really competitive biological conditions, and may improve on the currently used systems.

"We have named the dye 'Mallard Blue', after the record-breaking steam train, 'Mallard' which is housed in the railway museum here at York. Our dye is the same colour as the locomotive, and we believe it is similarly ground-breaking in its performance."

The York researc
'/>"/>

Contact: David Garner
david.garner@york.ac.uk
44-019-043-22153
University of York
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers make racehorses fertile
2. Canadas aquatic ecosystems research gets boost from NSERC
3. FASEB joins President Obama in urging Congress to sustain investments in research and innovation
4. World first for fly research
5. Research improving breast cancer treatment by targeting tumor initiating cells
6. Explosive breakthrough in research on molecular recognition
7. Cities can reduce greenhouse gas emissions by 70 percent, says U of T researcher
8. USC researchers find possible genetic clues to organ development, birth defects
9. Researchers discover Achilles heel for lymphoid leukemia
10. Researchers find Asian needle ants displacing other aggressive invaders
11. NIH grant funds Boston College research into illnesses afflicting people living with HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... 1, 2015  Automation and pre-processing are reducing ... screening. This is the first step toward a ... become unintrusive. An assortment of portal scanners, biometric ... investigations will transform the passenger screening process. ... Global Airport Passenger Screening Market ( http://www.frost.com/nf2b ...
(Date:8/31/2015)... Canada , August 31, 2015 ... of biometrics technology in government digitization projects to drive ... to a recently published TechSci Research report, " India Biometrics ... India is projected to grow at a ... the market is anticipated on account of extensive use of ...
(Date:8/31/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/st5b3m/saudi_arabia ) ... Biomedical Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... Saudi Arabia Biomedical Sensors market is estimated at $0.23 ... the period 2014-2020 The near future will ... formulation of each individual. These sensors can be set ...
Breaking Biology News(10 mins):The Future of Airport Security: Passenger Screening Transitioning Into an Invisible Process 2The Future of Airport Security: Passenger Screening Transitioning Into an Invisible Process 3The Future of Airport Security: Passenger Screening Transitioning Into an Invisible Process 4India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 2India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 3Saudi Arabia Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts (2014-2020) 2
... it, bread that contains critical nutrients could help combat ... of a group of Johns Hopkins University undergraduate students ... so that it yields beta carotene, the orange substance ... turns into vitamin A. The students, project ...
... likely, you would be disgusted if confronted with a ... worms. Or a particularly bloody wound. Or a horribly ... disgust you feel may lend important insight into your ... scientists closely measured people,s physiological reactions as they looked ...
... -- Low levels of a brain protein that regulates gene ... disorder, a complex and sometimes disabling psychiatric disease. As reported ... journal of The International Society for Bipolar Disorders, levels of ... of the brain in postmortem samples from patients with bipolar ...
Cached Biology News:Students coax yeast cells to add vitamins to bread 2Students coax yeast cells to add vitamins to bread 3Students coax yeast cells to add vitamins to bread 4That's gross!: Study uncovers physiological nature of disgust in politics 2Gene regulatory protein is reduced in bipolar disorder 2Gene regulatory protein is reduced in bipolar disorder 3
(Date:9/1/2015)... ... September 01, 2015 , ... ... Business Development, Asia Pacific. In this newly-created position, Gibbs will lead iLab’s business ... of iLab’s suite of tools. This entails not only introducing iLab to potential ...
(Date:8/31/2015)... ... 31, 2015 , ... The Global Supply Chain Resiliency Council ... resiliency practitioners with luminaries and thought leaders to advance the professional discipline through ... innovations and performance excellence. At that time its principle sponsor, Resilinc , ...
(Date:8/31/2015)... , Aug. 31, 2015 Research and Markets ... "Mexico Biomedical Sensors Market - Growth, Trends & ... The Mexico Biomedical Sensors market is estimated ... 2.68% over the period 2014-2020 The near ... the genetic formulation of each individual. These sensors can ...
(Date:8/31/2015)... 2015  RXi Pharmaceuticals Corporation (NASDAQ: RXII ... developing innovative therapies primarily in the areas of ... review period following the filing of the Company,s ... the U.S. Food and Drug Administration (FDA) has ... Logo -  http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ...
Breaking Biology Technology:iLab Solutions Hires Gerard Gibbs, Director of Business Development, Asia Pacific 2iLab Solutions Hires Gerard Gibbs, Director of Business Development, Asia Pacific 3Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3Mexico Biomedical Sensors Market Report 2015-2020 2RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 2RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 3RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 4
... , SAN DIEGO, Calif., INDIANAPOLIS, Ind., and CAMBRIDGE, ... ), Eli Lilly and Company (NYSE: LLY ) and Alkermes, ... 20 studies at the 45th Annual Meeting of the European Association for ... 29 to Oct. 2. The companies will present the latest research findings ...
... ... million round of funding. Participating investors included CTTV Investments LLC, the venture capital ... , ... Francisco, CA (PRWEB) September 24, 2009 -- LS9, Inc., the Renewable Petroleum Company™, today ...
... , , PHILADELPHIA and LONDON, ... -- researchers likely to be in contention for Nobel honors -- in anticipation ... be announced from October 5-12. , , Thomson Reuters ... Nobel Prize winners. , , Each year, data ...
Cached Biology Technology:Amylin and Lilly to Present More than 20 Studies for Exenatide at EASD 2009 2Amylin and Lilly to Present More than 20 Studies for Exenatide at EASD 2009 3Amylin and Lilly to Present More than 20 Studies for Exenatide at EASD 2009 4Amylin and Lilly to Present More than 20 Studies for Exenatide at EASD 2009 5Amylin and Lilly to Present More than 20 Studies for Exenatide at EASD 2009 6Amylin and Lilly to Present More than 20 Studies for Exenatide at EASD 2009 7LS9 Secures $25 Million in Latest Round of Funding 2LS9 Secures $25 Million in Latest Round of Funding 3Thomson Reuters Predicts Nobel Laureates 2Thomson Reuters Predicts Nobel Laureates 3Thomson Reuters Predicts Nobel Laureates 4Thomson Reuters Predicts Nobel Laureates 5Thomson Reuters Predicts Nobel Laureates 6
... This product has been developed to significantly ... labeled proteins. Stability is increased at ... 2-8 centigrade. This product is subjected ... mercury or azide. This formulation insures ...
... Blot Strong Antibody Stripping Solution is effective ... that have been developed with chemiluminescence or ... not recommended for stripping colorimetric substrates (TMB, ... possible to effectively remove substrates that precipitate ...
...
... low-pressure system, 100-120 V, is used for ... The system includes the Helios gene gun, ... station, syringe kit, tubing cutter, Helios gene ... The dimensions of the gene gun are ...
Biology Products: