Navigation Links
Research offers insight to how fructose causes obesity and other illness
Date:2/27/2012

AURORA, Colo. (Feb. 27, 2012) - A group of scientists from across the world have come together in a just-published study that provides new insights into how fructose causes obesity and metabolic syndrome, more commonly known as diabetes.

In this study which was performed in lab animals, researchers found that fructose can be metabolized by an enzyme that exists in two forms. One form appears to be responsible for causing how fructose causes fatty liver, obesity, and insulin resistance. The other form may actually protect animals from developing these features in response to sugar. These studies may provide important insights into the cause of the prediabetic condition known as "metabolic syndrome", which currently affects more than one-quarter of adults in the United States.

The study, "Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice" was published today in the journal Proceedings of the National Academy of Sciences. Richard Johnson, MD, the senior author of the study and Chief of the Division of Renal Diseases and Hypertension at the University of Colorado School of Medicine said the findings are significant because we now have a better understanding of how fructose causes obesity and other illnesses.

"These studies provide new insights into how fructose may contribute to the development of obesity and diabetes. In particular, the identification of contrasting roles for two enzymes that are involved in fructose metabolism was surprising and could be important in understanding why some individuals may be more sensitive to the metabolic effects of fructose than others."

Previous research has shown that fructose intake in added sugars such as sucrose and high fructose corn syrup is strongly linked to the epidemic rise in obesity and nonalcoholic fatty liver disease. Fructose intake also causes features of metabolic syndrome in laboratory animals and humans. It is
'/>"/>

Contact: Jackie Brinkman
jackie.brinkman@ucdenver.edu
303-724-1525
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... repeated climatic shifts over the last 120,000 years ... a team of researchers led by City College ... a new biodiversity metric called "phylogeographic endemism." , ... variation within species is restricted in geographical space. ... and 14 other researchers from institutions in Brazil, ...
(Date:8/29/2014)... available in German . ... the natural nitrogen cycle on Earth and in biological ... thought to depend on nitrite as their source of ... Daims, a microbiologist at the University of Vienna, has ... an alternative source of energy. The oxidation of hydrogen ...
(Date:8/29/2014)... phytoplankton, such as the prolific bloomer Emiliania huxleyi ... have discovered. The finding contradicts the common view that ... depend on scarce supplies of thiamine in the ocean ... think about the ocean," says CIFAR Senior Fellow ... paper with CIFAR fellows John Archibald ...
Breaking Biology News(10 mins):CCNY team defines new biodiversity metric 2Hydrogen powers important nitrogen-transforming bacteria 2Hydrogen powers important nitrogen-transforming bacteria 3Not all phytoplankton in the ocean need to take their vitamins 2Not all phytoplankton in the ocean need to take their vitamins 3
... study of the sense of smell lends support to ... the shape and the vibrational characteristics of odorant molecules. ... , demonstrates the feasibility of the theory first proposed ... chemical bonds the wagging, stretching and rocking of the ...
... A new model system of the cellular skeletons of ... explore how the cells, functional structures assemble. A paper ... by physicist Volker Schaller and his colleagues from the ... It hinges on the findings that a homogeneous protein ...
... November 11-14, 2012 WHERE: The Knoxville ... 2012 is the 60th Annual Meeting of the Entomological Society ... attend. The theme is "A Global Society for a Global ... 2,500 presentations on subjects such as bed bugs, honey bees, ...
Cached Biology News:Odorant shape and vibration likely lead to olfaction satisfaction 2Odorant shape and vibration likely lead to olfaction satisfaction 3Self-forming biological scaffolding 2
(Date:8/28/2014)... Exciting new work by a Florida State University research ... can take your temperature, emit white light, and convert ... molecule looks like a butterfly. , Biwu Ma, associate ... in the FAMU-FSU College of Engineering, created the molecule ... continued to discover that his creation has many other ...
(Date:8/28/2014)... Earlier this month, a report was created by ... Air Force on the performance of vehicles using an ... of fuel made from mustard seeds, offered great potential ... Eco friendly future. In fact, every branch of the ... of foreign oil over the next few years. They ...
(Date:8/28/2014)... August 28, 2014 Whitehouse Laboratories is ... term partnership with PTI Inspection Systems that ... state of the art leak testing method development and ... instruments currently available. As part of this agreement, Whitehouse ... Voltage Leak Detection Instrument developed and manufactured by ...
(Date:8/27/2014)... , Aug. 27, 2014 Rhythm, a biopharmaceutical ... genetic deficiencies that result in metabolic disorders, announced today ... S-1 with the U.S. Securities and Exchange Commission (SEC) ... of its common stock. The number of shares to ... have not yet been determined. Citigroup and ...
Breaking Biology Technology:Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 4Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 5Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3Rhythm Files Registration Statement for Proposed Initial Public Offering 2
... Calif., May 24, 2012 Questcor Pharmaceuticals, Inc. (NASDAQ: ... at the Jefferies 2012 Global Healthcare Conference in New York ... a.m. ET. A live webcast and subsequent archived ... .  The replay will be available for approximately 90 days ...
... Reportlinker.com announces that a new market ... Optical Coatings: Technologies ... http://www.reportlinker.com/p0157456/Optical-Coatings-Technologies-and-Global-Markets.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Paint_and_Coating INTRODUCTION , ... study analyzes the status of global markets ...
... conventional and current solar cells include high production cost, ... on toxic and scarce materials. Northwestern University researchers have ... minimize all of these solar energy technology limitations. ... the problem of the Grtzel cell, a promising low-cost ...
Cached Biology Technology:Questcor Pharmaceuticals to Present at Jefferies 2012 Global Healthcare Conference 2Optical Coatings: Technologies and Global Markets 2Optical Coatings: Technologies and Global Markets 3Optical Coatings: Technologies and Global Markets 4Optical Coatings: Technologies and Global Markets 5Optical Coatings: Technologies and Global Markets 6Optical Coatings: Technologies and Global Markets 7Optical Coatings: Technologies and Global Markets 8Optical Coatings: Technologies and Global Markets 9Optical Coatings: Technologies and Global Markets 10Optical Coatings: Technologies and Global Markets 11Optical Coatings: Technologies and Global Markets 12Taking solar technology up a notch 2Taking solar technology up a notch 3