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Random walks on DNA
Date:4/19/2013

as forwards.

Mark Szczelkun, Professor of Biochemistry from the University's School of Biochemistry and one of the senior authors of the study, said: "This enzyme uses the energy from ATP to force a change in protein conformation rather than to unwind DNA. The movement on DNA thereafter doesn't require an energy input from ATP. Although movement is random, it occurs very rapidly and the enzyme can cover long distances on DNA faster than many ATP-driven motors. This can be thought of as a more energy-efficient way to move along DNA and we suggest that this mechanism may be used in other genetic processes, such as DNA repair."


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Contact: Caroline Clancy
caroline.clancy@bristol.ac.uk
44-011-792-88086
University of Bristol
Source:Eurekalert

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