Navigation Links
Putting the spring back in broken hearts
Date:9/23/2013

and so yields more functional tissue. Earlier this year, they published research on integrating gold particles into cardiac tissue to optimize electrical signaling between cells.

More recently, the researchers identified spiral-shaped collagen fibers in the extracellular matrix of rat hearts. Seeing the potential for an advance, they set out to recreate them for the first time. After fabricating the spring-like fibers using advanced techniques, they subjected them to a variety of tests.

As the researchers predicted, the spring-like fibers showed better mechanical properties than straight fibers, with especially improved elasticity. And compared to tissue engineered with straight fibers, the tissue engineered with spring-like fibers contracted with greater force and less mechanical resistance.

"These properties are very important, because we want to transplant the tissue into the human heart, which expands and contracts constantly," says Fleischer.

Saving lives

Heart disease is responsible for a third of all deaths in the United States, according to a 2013 American Heart Association report. The researchers in Dr. Dvir's lab hope that tissue engineered with spring-like fibers will help fight this epidemic, improving and prolonging the lives of millions of people.

But additional research is needed first. The researchers say the processes for fabricating the fibers and assembling them into a scaffold need to be refined. Most importantly, they say, the ability of the tissue to improve heart function after a heart attack needs to be tested in humans something they plan to do in pre-clinical and then clinical trials.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Putting flesh on the bones of ancient fish
2. Kirk, Spock together: Putting emotion, logic into computational words
3. GSA Today: Putting time in its place
4. Putting plants online: 4 leading botanical gardens to create first online catalog of all plants
5. Journal of Control, Automation and Electrical Systems now published by Springer
6. Offspring of mothers stressed during pregnancy with a passive stress coping style more prone to obesity
7. A maternal junk food diet alters development of opioid pathway in the offspring
8. High folate gestational and post-weaning diets in Wistar rat offspring
9. Springer announces impact factor increases for journals in 2012
10. Submarine springs reveal how coral reefs respond to ocean acidification
11. Springer launches French- and Italian-language eBook collections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 21, 2014 Aware, Inc. (NASDAQ: AWRE ... reported financial results for its third quarter ended September 30, ... was $6.0 million, an increase of 40% compared to $4.3 ... the third quarter of 2014 was $4.1 million compared to ... income in the current three month period was primarily due ...
(Date:10/18/2014)... a group of 2,000 patients referred for evaluation ... potential molecular diagnosis for 25 percent, including detection ... new mutations contributing to disease, according to a ... is being released to coincide with the American ... sequencing analyzes the exons or coding regions of ...
(Date:10/17/2014)... German . ... in order to reproduce? And why are there two sexes ... latest issue of the research journal Molecular Human Reproduction ... Ramm from Bielefeld University Bielefeld has compiled this special issue ... a female to copulate with several males in quick succession ...
Breaking Biology News(10 mins):Aware, Inc. Reports Third Quarter 2014 Financial Results 2Aware, Inc. Reports Third Quarter 2014 Financial Results 3Aware, Inc. Reports Third Quarter 2014 Financial Results 4Aware, Inc. Reports Third Quarter 2014 Financial Results 5Aware, Inc. Reports Third Quarter 2014 Financial Results 6Aware, Inc. Reports Third Quarter 2014 Financial Results 7Whole-exome sequencing shows potential as diagnostic tool 2Sperm wars 2
... sour apple and you destroy them plant cell vacuoles. ... plant cells, only little was known about how these cellular ... their way there. Scientists at the Technische Universitaet Muenchen (TUM) ... of vacuoles. In the process they uncovered new clues that ...
... release is available in Spanish . ... tool for improving the expression of desirable genes in rice ... the most good. Roger Thilmony, a geneticist with USDA,s ... promoter can be used to direct other introduced genes to ...
... University of Illinois metabolic engineer has taken the first ... biofuels by developing a strain of yeast with increased ... of biomass crops, which yield the alcohol-based fuels ethanol ... to convert sugars from biomass into biofuels. ...
Cached Biology News:Researchers discover how the storehouses of plant cells are formed 2Researchers discover how the storehouses of plant cells are formed 3New genetic tool helps improve rice 2Scientist IDs genes that promise to make biofuel production more efficient, economical 2
(Date:10/22/2014)... Research and Markets has ... Diagnostics Market (Product types, Application, Technology, End User ... Profiles, Demand, Insights, Analysis, Research, Report, Opportunities, Segmentation ... their offering. This new report ... users and Geography) Global Size, Industry Analysis, Trends, ...
(Date:10/22/2014)... October 21, 2014 Shimadzu Scientific Instruments ... data tool for the pain management and clinical markets. ... processing and review by allowing users to highlight and ... , QuantAnalytics allows analysts to filter results by ... data processing by eliminating the need to sift through ...
(Date:10/22/2014)... Khaimah, UAE (PRWEB) October 22, 2014 ... life science and healthcare projects, announces the addition of ... DRCOG DCH to its advisory team. Dr. Siddiqui will ... team. , A graduate of University College ... was subsequently degreed in medicine in 2001. With further ...
(Date:10/22/2014)... /PRNewswire/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... its Oral Amphotericin B program.  The company recently ... work involving samples from HIV/AIDS patients exposed ... pre clinical studies and regulatory filings to move ... utilizing approximately $700,000 of funding and technological advice ...
Breaking Biology Technology:Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 2Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 3Shimadzu Releases QuantAnalytics Open Access LCMS Software Package for Clinical Applications 2Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3
... Research and,Engineering (IMRE), led by Professor Christian Joachim 1 ... first in the world to invent a,molecular gear of ... This achievement marks a radical shift in the scientific ... 2009 2 in Nature Materials 3 ...
... ... and control devices and level gauges, today announced that it has acquired certain assets ... liquid delivery solutions for the global semiconductor, solar, and electronics industries. Financial terms of ... ...
... Role of Chairman of the Board - , , ... INSM ), a biopharmaceutical company, today announced that Geoffrey Allan, ... Chairman of the Board of Directors, effective immediately, due to ... President, Chief Executive Officer and Chairman of the Board since ...
Cached Biology Technology:A*STAR scientists invent the world's only controllable molecule gear of minuscule size of 1.2nm 2Brooks Instrument Completes Acquisition of Celerity's Instrumentation Division 2Brooks Instrument Completes Acquisition of Celerity's Instrumentation Division 3Insmed CEO Resigns Due to Health Concerns 2Insmed CEO Resigns Due to Health Concerns 3