Navigation Links
Prostate Cancer Foundation announces new urine test for prostate cancer available
Date:9/26/2013

ine health screening measure for men of a certain age. What everyone does agree upon is the need for better markers of prostate cancer. To date there are no perfect biomarkers that identify only high-risk prostate cancer. But each year progress is made toward such a goal. Today, the University of Michigan's Department of Pathology MLabs will begin offering the MiPS urine test that is ultra specific for prostate cancer. The MiPS test scans urine samples for two molecular markers that are distinct to prostate cancer. One marker is a snippet of RNA made from a gene (PCA3) that is overactive in 95 percent of all prostate cancers. The second marker is RNA that is made only when two genes (TMPRSS2 and ERG) abnormally fuse. The presence of this fusion RNA in a man's urine is ultra specific for prostate cancer.

An ultra-specific test for prostate cancer

  • Dr. Scott Tomlins, MD, PhD, is an assistant professor of pathology and urology at the University of Michigan and a Safeway-Prostate Cancer Foundation Young Investigator. Tomlins co-discovered what is now commonly known as the TMPRSS2:ERG fusion. "The evidence shows that if TMPRSS2:ERG RNA is detectable at high levels in urine, a man likely has prostate cancer, whether or not his biopsy is positive for cancer," said Tomlins. (Because biopsies typically sample less than 1 percent of the prostate gland, cancers can be missed, even high-grade cancers.)

    A commercial urine test (PROGENSA PCA3) for PCA3, developed and marketed by the California-based biotech company Gen-Probe, gained FDA approval in 2012 for use in men who are considering repeat biopsy after an initially negative result. While a welcome development, research shows that the new urine test offered by MLabs that measures both PCA3 and TMPRSS2:ERG should improve a doctor's ability to stratify men suspected of having prostate cancer. In a study published in Science Translational Medicine, Tomlins and colleagues
    '/>"/>


Contact: Rebecca Levine
rlevine@pcf.org
310-570-4727
Prostate Cancer Foundation
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Wistar receives $1.5 million Department of Defense grant to ready prostate drug for clinical use
2. Study highlights possible new approach to prostate cancer treatment
3. Which Prostate Cancers Really Need Treatment?
4. Using big data to identify prostate cancers and best treatments
5. UCI chemists devise inexpensive, accurate way to detect prostate cancer
6. PARP inhibitor shows activity in pancreatic, prostate cancers among patients carrying BRCA mutations
7. Soy and tomato combo may be effective in preventing prostate cancer
8. Particular DNA changes linked with prostate cancer development and lethality
9. Nonsurgical treatment turns back the clock, shrinks enlarged prostate
10. First genetic factor in prostate cancer prognosis identified
11. Landmark study describes prostate cancer metastasis switch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... Boston, MA A study published online in the ... describes a novel approach to preventing cervical cancer based ... cervical cancer after removal of a discrete population of ... from a study that looked at squamocolumnar junction cells, ... canal and have been implicated as the origins of ...
(Date:7/25/2014)... University of Adelaide has opened the way for the development ... , In Australia, annual barley production is second only to ... one of the most important diseases of barley. , Senior ... composition of special growths on the cell walls of barley ... leaf. , The research, by the ARC Centre of Excellence ...
(Date:7/25/2014)... study shows that the age girls reach puberty is influenced ... on which parent contributes the gene. This is the ... development after birth and details of this study were published ... the first period, known as menarche, is a marker for ... that the onset of menses varies between girls, is an ...
Breaking Biology News(10 mins):Clearing cells to prevent cervical cancer 2New hope for powdery mildew resistant barley 2Could age of first period influence development of diseases in older women? 2
... controlling cell-membrane fat play a key role in turning off ... Chicago think so, and a biosensor they,ve created that measures ... treatment. Wonhwa Cho, distinguished professor of chemistry, and his ... act as sensors for lipid levels. Their findings are ...
... The genomic analysis technologies enable the study of genetic ... researches brought such a big and useful volume of ... published in Nature Genetics , promoted by the ... analysis and identifies three new chromosomal regions implicated in ...
... Secretary of the Interior Ken Salazar announced on October ... a consortium led by the University of Hawaii at Manoa, ... Guam. Together with two other new regional climate science centers, ... a network of eight regional centers being established by the ...
Cached Biology News:New membrane lipid measuring technique may help fight disease 2Genome-wide studies have identified new genes involved in susceptibility to melanoma 2University of Hawai'i chosen for new Climate Science Center 2University of Hawai'i chosen for new Climate Science Center 3
(Date:7/24/2014)... July 24, 2014 -- A novel combination of microscopy ... of Energy,s Oak Ridge National Laboratory an unprecedented look ... unusual physical and electrochemical properties. , The research ... affects the surface of a perovskite manganite, a complex ... new avenue to understand surface behavior could benefit researchers ...
(Date:7/24/2014)... on sophisticated equipment, trained personnel, and detection dogs ... terrorist attacks. A revolutionary new electronic chip with ... job much easier. , The groundbreaking nanotechnology-inspired sensor, ... University ,s School of Chemistry and Center for ... company Tracense, picks up the scent of explosives ...
(Date:7/24/2014)... Research and Markets has announced ... 2014-2018" report to their offering.  ... the in vitro growth of plant or animal cells ... biopharmaceutical production. Cell culture is a crucial step in ... cell culture consumables are necessary for the in vitro ...
(Date:7/24/2014)... 24, 2014 Three companies from the ... Livestrong’s Big C Competition. Out of 700 competition entrants, ... to the semi-final round. In this round twenty teams ... program, complete with mentoring from thought-leaders and medical entrepreneurs ... of the angelMD commitment to the Livestrong vision around ...
Breaking Biology Technology:ORNL study reveals new characteristics of complex oxide surfaces 2Nano-sized chip 'sniffs out' explosives far better than trained dogs 2Global Cell Culture Market 2014-2018: Key Vendors are Becton, Dickinson and Co, EMD, GE Healthcare, Lonza Group, Sigma Aldrich and Thermo Fisher Scientific 23 angelMD Startups Make Livestrong Big C Semi-finals 2
... around the Midwest looking for new ways to increase ... of bringing in developers to develop open lands and ... with tax incentives and reduced fees to relocate a ... common practice with even large municipalities in Chicago giving ...
... and consumer rights group believes the U.S. Supreme Court's ... Wisconsin Alumni Research Foundation regarding its stem cell ... its recent $1 million jury reward in the Xenon ... ,Representatives of the Foundation for Taxpayer and Consumer ...
... Boston, and youre on the verge of investing big bucks in ... team is in place, the business plan is tight, and the ... into the room, clears her throat and asks if youve ever ... check, she says, until you learn more about it. , ...
Cached Biology Technology:Electronic signs for municipalities: Las Vegas or lost revenues? 2Electronic signs for municipalities: Las Vegas or lost revenues? 3Electronic signs for municipalities: Las Vegas or lost revenues? 4California group says ruling weakens WARF's stem cell patent 2California group says ruling weakens WARF's stem cell patent 3California group says ruling weakens WARF's stem cell patent 4Why repealing the shareholder wage lien law makes sense 2Why repealing the shareholder wage lien law makes sense 3