Navigation Links
Progress in tissue engineering to repair joint damage in osteoarthritis
Date:6/8/2011

Medical scientists now have "clear" evidence that the damaged cartilage tissue in osteoarthritis and other painful joint disorders can be encouraged to regrow and regenerate, and are developing tissue engineering technology that could help millions of patients with those disorders. That's the conclusion of a new analysis of almost 100 scientific studies on the topic, published in ACS's journal Molecular Pharmaceutics.

Tong Cao, Wei Seong Toh and colleagues point out that damage to so-called articular cartilage the smooth, white, rubbery tissue that covers and cushions the ends of bones in joints is one of the most challenging problems in medicine. That's because the tissue lacks blood vessels and has little ability to repair itself and regrow. Wear-and-tear damage thus builds up over the years, resulting in conditions like osteoarthritis, which affects 27 million people in the United States alone. Osteoarthritis is a fast-growing public health problem because of the world's aging population and because of a sharp increase in obesity, which increases wear on joint cartilage. To assess progress toward medical use of tissue engineering to treat joint damage, the researchers scanned global research on the topic.

They found that scientists have developed many new tissue engineering methods, including implantation of so-called "scaffolds" made of biomaterials that mimic cartilage matrix in the body. The scaffolds could guide the transplanted cells, orchestrate the host cell response, provide structures and microenvironment substances to help rebuild cartilage at the injury site. "In summary, there is promise in future research involving the development of multi-functional biomaterial delivery systems that affect cartilage tissue regeneration on multiple levels," the article states.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Chesapeake Bay programs 2-year milestones improve upon past strategies, but accounting of progress remains a challenge
2. GOLFIG increased progression-free survival in colorectal cancer patients
3. Progress toward the clinical application of autologous induced pluripotent stem cells and gene repair therapy for treatment of familial hypercholesterolemia
4. Older and stronger: Progressive resistance training can build muscle, increase strength as we age
5. Researchers find drug that stops progression of Parkinsons disease in mice
6. Neiker-Tecnalia makes progress in detection and prevention of infection by visna maedi virus
7. Researchers learn why PSA levels reflect prostate cancer progression
8. Progress toward treating infections by silencing microbes smart phones
9. Progress toward first commercial repellent for East Coasts stinker
10. Erlotinib improves progression-free survival as first-line therapy in advanced lung cancer
11. Gene-environmental interactions and MS progression is focus of new study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2016)... Nov. 30, 2016  higi SH llc (higi) ... initiative targeting national brands, industry thought-leaders and celebrity ... respective audiences for taking steps to live healthier, ... in 2012, higi has built the largest self-screening ... 38 million people who have conducted over 185 ...
(Date:11/24/2016)... , Nov. 23, 2016 Cercacor today ... athletes and their trainers non-invasively measure hemoglobin, ... Pulse Rate, and Respiration Rate in approximately 30 seconds. ... users easy and immediate access to key data about ... of a training regimen. Hemoglobin carries ...
(Date:11/17/2016)... Market Watch: Primarily supported by ownership types; Private ... market is to witness a value of US$37.1 billion by ... Annual Growth Rate (CAGR) of 10.75% is foreseen from ... North America is not way behind ... at 9.56% respectively. Report Focus: The ...
Breaking Biology News(10 mins):
(Date:12/5/2016)... GRAND RAPIDS, Mich. , Dec. 5, 2016 NxGen MDx ... "By bringing the test in house, we,ve been able to improve ... costs down for patients," says Alan Mack , CEO of NxGen ... , , ... increase in test volume has led to more job opportunities at the ...
(Date:12/5/2016)... 5, 2016 The U.S. Biotechnology ... $108 billion of revenue and some $890 billion of ... on global biopharmaceuticals, and this figure is expected to ... lined up these four equities for assessment: Northwest Biotherapeutics ... (NASDAQ: ACAD ), Acorda Therapeutics Inc. (NASDAQ: ...
(Date:12/4/2016)... Dec. 3, 2016  In five studies being presented ... Annual Meeting and Exposition in San Diego ... to improve the delivery of life-saving treatments to patients ... are designed to carry therapies directly to the sites ... could provide a substantial advantage over traditional, systemic methods. ...
(Date:12/2/2016)... , Dec. 2, 2016 More than $4.3 ... 11th Double Helix Medals dinner ( DHMD ). The gala was held ... New York City and honored Alan ... contributions, respectively, to health and medicine and the public understanding ... in 2006, the event has raised $40 million for ...
Breaking Biology Technology: