Navigation Links
Professor publishes on first-ever imaging of cells growing on spherical surfaces
Date:9/21/2012

MELBOURNE, FLA.Shengyuan Yang, Florida Institute of Technology assistant professor of mechanical and aerospace engineering, with graduate student Sang Joo Lee, has published a paper on the first-ever imaging of cells growing on spherical surfaces. The paper is published in the online journal, Review of Scientific Instruments, and will appear later in September in the print version.

The potential biomedical applications of the researchers' technique include new strategies and devices for the early detection and isolation of cancer cells, facilitating new methods of treating cancer tissues. "We also foresee new strategies and techniques to control the differentiation of stem cells and the morphologies and structures of the resulting cells and tissues," said Yang.

The effects of substrate stiffness on cell behaviors have been extensively studied; however, the effects of substrate curvature are not well-documented. The curvature of the surface on which cells adhere can have profound effects on cell behaviors, according to Yang.

"To reveal these cell mechano-biological responses to substrate curvatures, we have introduced a novel, simple, and flexible class of substrates, polyacrylamide gels embedded with micro glass balls ranging in diameter from 5 mm to 2 mm, to culture cells. To the best of our knowledge, this is the first experimental attempt to study cell responses to spherically-shaped substrates. Our cell culture experiments imply that this class of substrates, micro glass ball embedded gels, can be useful tools to study cell mechanobiological responses to substrate curvatures, related cell and tissue engineering researches, and biomedical applications, such as cancer detection and treatment, and the control of stem cell differentiations, for example," said Yang.

This work was supported with funding from the National Science Foundation (NSF) CAREER Program. The reviewer of this paper at Review of Scientific Instruments commented, according to Yang: "This is a clever idea. . . This work has great potentials with high impact."


'/>"/>

Contact: Karen Rhine
krhine@fit.edu
321-674-8964
Florida Institute of Technology
Source:Eurekalert

Related biology news :

1. Study by Haverford College professor reveals unprecedented impact of Deepwater Horizon on deep ocean
2. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
3. Scripps Research Institute Professor Gerald F. Joyce elected to American Academy of Arts & Sciences
4. Professor known for work with hunter-gatherers elected to American Academy of Arts and Sciences
5. Mainz University Medical Center attracts funding of Alexander von Humboldt Professorship
6. NJIT professor awarded patent today for new desalination devices, more
7. UI professor identifies largest known crocodile
8. Biology professor secures grant to save West Virginias primary natural history collection
9. Florida Tech biological sciences professor earns $257,000 NSF grant to study coral diseases
10. Purdue professor to speak before Congress about nanotechnology in brain treatment research
11. Normal bacterial makeup has huge implications for health, says CU professor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... , Feb. 11, 2016  According to new research ... mainstream. More than 200 fingerprint, iris, and eye-vein ... under 70 brand names. This includes market leaders ... ZTE. Acuity projects that 600 million biometric smartphones ... global installed base. Maxine Most , ...
(Date:2/11/2016)...  Vigilant Solutions announces today that its license plate recognition ... Lee,s Summit Police Department to improve ... of a homicide suspect. Kansas City ... square miles and is home to roughly 100,000 residents. ... mobile license plate reader system and also leverages Vigilant,s network ...
(Date:2/10/2016)... India , February 10, 2016 /PRNewswire/ ... --> According to 2016 iris recognition ... identification iris recognition is more widely accepted ... available with both fingerprint and iris recognition ... the user to avoid purchasing two individual ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... ... , ... Global Stem Cells Group has announced an inaugural conference ... Quito, Ecuador, Feb. 24-March 6, 2016. The new facility will provide advanced protocols and ... Stem Cells Group CEO Benito Novas will host the event, which will begin with ...
(Date:2/12/2016)... , Feb. 12, 2016 Biocom, the association representing ... took a group of San Diego ... of its 2016 Precision Medicine Advocacy Fly-In. Biocom Fly-In participants ... and Drug Administration (FDA), the Centers for Medicare and Medicaid ... as San Diego U.S. Representatives Susan Davis and ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Pittcon 2016 Exposition, which ... will include 848 exhibitors (count as of February 9) of which 119 are ... used by the scientific community in industrial, academic, and government labs. The Exposition ...
(Date:2/12/2016)... , Feb. 12, 2016  BD (Becton, Dickinson and ... technology company, today announced the launch of the BD ... and Technology (AGBT) Meeting. --> ... genomic research by providing cost effective NGS library preparation ... a high-throughput, fully integrated, next generation sequencing (NGS) library ...
Breaking Biology Technology: