Navigation Links
Preclinical studies use specialized ultrasound to detect presence of cancer
Date:7/10/2012

From the air, the twists and turns of rivers can easily be seen. In the body, however, tracing the twists and turns of blood vessels is difficult, but important. Vessel "bendiness" can indicate the presence and progression of cancer.

This principle led UNC scientists to a new method of using a high-resolution ultrasound to identify early tumors in preclinical studies. The method, based on vessel bendiness or "tortuosity," potentially offers an inexpensive, non-invasive and fast method to detect cancer that could someday help doctors identify cancers when tumors are less than a centimeter in size.

Their findings were published in the July 6, 2012 online issue of the journal Radiology.

Paul Dayton, PhD, associate professor of biomedical engineering explains, "The correlation between vessel tortuosity and cancer is well-established. What's new about our finding is that we can visualize these vessels in minutes with a very quick scan, using very inexpensive imaging methods." Dr. Dayton is a member of UNC Lineberger Comprehensive Cancer Center.

The UNC team used a new high-resolution ultrasound method, called "acoustic angiography," with an intravascular contrast agent that allowed them to acquire images of only the blood vessels. "Unlike current clinical 'grayscale' ultrasound, this method filters out all tissue signals, so we can see small blood vessels clearly." says Dayton.

"Our results showed a definitive difference between vessels within and surrounding tumors versus those associated with normal healthy vasculature. The limitation that we must now address is that our method works only for tumors at a shallow depth into tissue, such as melanomas or thyroid cancer. Our next studies will focus on this imaging-depth issue as well as evaluating the ability of this technology to determine a tumor's response to therapy.

"We know from several clinical and preclinical MRI studies at UNC by Elizabeth
'/>"/>

Contact: Dianne G. Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
2. Studies reveal structure of EV71, a virus causing childhood illnesses
3. Autism Speaks awards $1.1 million to fund high priority studies
4. Improving equine health: Research studies vaccinations to protect newborn foals
5. Miniature Sandia sensors may advance climate studies
6. 2 Cell Transplantation studies impact dental stem cell research for therapeutic purposes
7. GSA Bulletin presents studies in Antarctica, Italy, Mexico, Algeria, Mongolia, and more
8. Dinosaur fossil: Even specialized predators didnt turn down free meals
9. Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
10. Acoustic tweezers capture tiny creatures with ultrasound
11. Gold nanoantennas detect proteins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Preclinical studies use specialized ultrasound to detect presence of cancer
(Date:12/17/2014)... 15, 2014 The Defense Logistics Agency is insourcing ... prevent counterfeit microcircuits from entering into its supply chain. ... microcircuit anti-counterfeit initiative dubbed DNA marking. The capability will ... reliability throughout the supply chain. The new quality control ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... the "Global Facial Recognition Market 2015-2019" report ... Facial recognition is a technology used ... the overall facial feature of a person such as ...
(Date:12/10/2014)... NEW YORK , Dec. 8, 2014 You,ve been here ... but can,t remember your password, site key or the answer to ... grade teacher? Today, Hoyos Labs , a ... finally put an end to the frustration that comes with usernames, ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... cancer patients unnecessarily undergo surgery or harsh treatments ... slow-growing and aggressive forms of the disease. Researchers ... Medical Institutes are developing technology that allows patients ... relatively mild treatments or take drastic measures. ...
... with autologous cord blood. Following a cardiac arrest with ... been in a persistent vegetative state with minimal ... the cord blood containing stem cells, the symptoms improved ... speak simple sentences and to move. "Our findings, along ...
... Frontiers, one of the world,s largest and fastest growing ... Frontiers in Bioengineering and Biotechnology . ... in Bioengineering and Biotechnology will provide a single ... research to be disseminated and discussed. ...
Cached Biology News:Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3First successful treatment of pediatric cerebral palsy with autologous cord blood 2Frontiers launches new open-access journal in Bioengineering and Biotechnology 2
(Date:1/22/2015)... Crystal Diagnostics (CDx) Xpress System, a rapid ... AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. coli ... to as STEC or the “Big-6”) as well as Escherichia ... per 325 g of raw ground beef and raw beef ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 zFlo Motion ... pleased to announce an exciting product from a new partner. ... analysis solutions over the past 15 years, with offerings in ... recently, their 3D IMU system (inertial measurement unit), iSen, is ...
(Date:1/22/2015)... 22, 2015 Controlled Substance Compliance Services ... helps companies check the legal requirements around using controlled ... China. , As their international operations expand and ... software solutions built as a result of the first ...
(Date:1/22/2015)... Diagenode, Inc., a leading global ... and complete solutions for epigenetics research, recently launched ... the need for manual processing. The new ChIPettor ... of histones or transcription factors and a semi-automated ...
Breaking Biology Technology:Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 23D Motion Capture Just Got Easy 2Global Compliance Service for Controlled Substances to Expand to China 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2
...  Halozyme Therapeutics, Inc. (NASDAQ: HALO) will be presenting at ... Francisco on Wednesday, January 11, 2012 at 2:00 p.m. ... Frost, Ph.D., president and chief executive officer of Halozyme ... http://photos.prnewswire.com/prnh/20100302/LA63139LOGO ) The presentation will be ...
... RANCHO CORDOVA, Calif., Jan. 4, 2012 ThermoGenesis Corp. (NASDAQ: ... process and store adult stem cells, said today that India,s ... the Company to initiate commercial sales of the product in ... cells from cord blood. "We are pleased to ...
... Jan. 4, 2012  Today, the Global Probiotics Council (GPC), ... LTD., announced the launch of the fifth annual Young ... two awards, each in the amount of $50,000, to ... to focus on the role of probiotics and gastrointestinal ...
Cached Biology Technology:ThermoGenesis Announces Approval of AXP® by India Ministry of Health 2ThermoGenesis Announces Approval of AXP® by India Ministry of Health 3Fifth Cycle of Probiotics & Microbiota Research Grant Announced 2Fifth Cycle of Probiotics & Microbiota Research Grant Announced 3Fifth Cycle of Probiotics & Microbiota Research Grant Announced 4
... The Label IT siRNA Tracker Intracellular Localization ... directly label and deliver siRNA, of your ... for in vitro tracking experiments. Subcellular localization ... can be monitored following introduction of the ...
... Invasion through the extracellular matrix (ECM) ... Cancer cells initiate invasion by adhering ... wall. Proteolytic enzymes, such as MMP ... covering (basement membrane) surrounding the blood vessels ...
... quick and reproducible immunoprecipitation (IP) by using a ... reproducible than regular IPs, which are problematic with ... disrupting the agarose bed. The binding of the ... and elution of the immune complex can occur ...
... Rabbit anti-Wilm's tumor, Polyclonal Antibody, ... IHC-P: Use at a dilution ... assay dependent dilution. WB: Use at ... weight: 51 kDa. Not tested in ...
Biology Products: