Navigation Links
Preclinical studies use specialized ultrasound to detect presence of cancer
Date:7/10/2012

From the air, the twists and turns of rivers can easily be seen. In the body, however, tracing the twists and turns of blood vessels is difficult, but important. Vessel "bendiness" can indicate the presence and progression of cancer.

This principle led UNC scientists to a new method of using a high-resolution ultrasound to identify early tumors in preclinical studies. The method, based on vessel bendiness or "tortuosity," potentially offers an inexpensive, non-invasive and fast method to detect cancer that could someday help doctors identify cancers when tumors are less than a centimeter in size.

Their findings were published in the July 6, 2012 online issue of the journal Radiology.

Paul Dayton, PhD, associate professor of biomedical engineering explains, "The correlation between vessel tortuosity and cancer is well-established. What's new about our finding is that we can visualize these vessels in minutes with a very quick scan, using very inexpensive imaging methods." Dr. Dayton is a member of UNC Lineberger Comprehensive Cancer Center.

The UNC team used a new high-resolution ultrasound method, called "acoustic angiography," with an intravascular contrast agent that allowed them to acquire images of only the blood vessels. "Unlike current clinical 'grayscale' ultrasound, this method filters out all tissue signals, so we can see small blood vessels clearly." says Dayton.

"Our results showed a definitive difference between vessels within and surrounding tumors versus those associated with normal healthy vasculature. The limitation that we must now address is that our method works only for tumors at a shallow depth into tissue, such as melanomas or thyroid cancer. Our next studies will focus on this imaging-depth issue as well as evaluating the ability of this technology to determine a tumor's response to therapy.

"We know from several clinical and preclinical MRI studies at UNC by Elizabeth
'/>"/>

Contact: Dianne G. Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
2. Studies reveal structure of EV71, a virus causing childhood illnesses
3. Autism Speaks awards $1.1 million to fund high priority studies
4. Improving equine health: Research studies vaccinations to protect newborn foals
5. Miniature Sandia sensors may advance climate studies
6. 2 Cell Transplantation studies impact dental stem cell research for therapeutic purposes
7. GSA Bulletin presents studies in Antarctica, Italy, Mexico, Algeria, Mongolia, and more
8. Dinosaur fossil: Even specialized predators didnt turn down free meals
9. Ultrasound idea: Prototype NIST/CU bioreactor evaluates engineered tissue while creating it
10. Acoustic tweezers capture tiny creatures with ultrasound
11. Gold nanoantennas detect proteins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Preclinical studies use specialized ultrasound to detect presence of cancer
(Date:9/2/2014)... most ideal source of nutrition for infants and ... the evolution and civilizations of human beings. Unlike ... number of bacterial species, including some opportunistic pathogens ... to scientists and physicians. , Indeed, the existence ... result of co-evolutionary and co-adaptive interactions between the ...
(Date:9/2/2014)... integrity? Tell the truth; everyone has a tipping point. We ... lie if the benefit is great enough. Now, scientists have ... that decision. , The result was published online this ... prefer to be honest, even if lying is beneficial," said ... at the Virginia Tech Carilion Research Institute , where ...
(Date:9/2/2014)... propensity for eating anything, including each other, camel crickets ... North Carolina State University finds that non-native camel cricket ... States. , "The good news is that camel crickets ... humans," says Dr. Mary Jane Epps, a postdoctoral researcher ... about the research. , The research stems from a ...
Breaking Biology News(10 mins):Are human breast milk microbiome 'neutral'? 2Are human breast milk microbiome 'neutral'? 3Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 2Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 3Scientists find possible neurobiological basis for tradeoff between honesty, self-interest 4Researchers find Asian camel crickets now common in US homes 2
... the triangle depicting how many servings of each food ... knows about MyPlate - the circle showing what a healthy ... United States Department of Agriculture (USDA) to help American consumers ... icon that prompts us to think about what,s on our ...
... gene therapy holds promise for the treatment of devastating genetic ... have been unclear. In a study online December 26th ... by Cell Press, researchers evaluated a patient with a genetic ... after he had undergone a gene therapy procedure as part ...
... neurodegenerative disorders, and drugs without significant side effects ... Institute of Synergon Consulting in Romania, led by ... is a transcription co-activator required for consolidation of ... same time involved in DNA replication and repair, ...
Cached Biology News:Who is using MyPlate? 2Gene therapy for human skin disease produces long-term benefits 2
(Date:9/2/2014)... about a billionth of a meter in size, are ... can benefit human health, as in some innovative early ... through viruses, air pollution, traffic emissions, cosmetics, sunscreen and ... in St. Louis, led by Lan Yang, PhD, the ... Systems Engineering, and their collaborators at Tsinghua University in ...
(Date:9/2/2014)... Scientists, including University of Oregon chemist Geraldine Richmond, ... of self-assembling, synthetic proteins called peptoid nanosheets that ... accomplishment -- detailed this week in a paper ... Proceedings of the National Academy of Sciences ... of the two-dimensional peptoid nanosheets that can be ...
(Date:9/2/2014)... 2, 2014 Persistence Market Research ... in Pharmaceutical, Biopharma and Life Sciences: North ... the global membrane technology market for pharmaceutical, biopharma and life sciences ... is expected to grow at a CAGR of 9.1% ... of USD 10,886.0 million in 2019. Browse ...
(Date:9/2/2014)... AVENTURA, Fla. , Sept. 2, 2014  Technology ... has announced that its wholly-owned subsidiary Renuell Int,l, Inc. ... National Aeronautics and Space Administration ("NASA") at the Johnson ... See photos: tapplic.com/houstonphotos/ ... stated, "We are very pleased to announce our latest, ...
Breaking Biology Technology:Engineers develop new sensor to detect tiny individual nanoparticles 2Engineers develop new sensor to detect tiny individual nanoparticles 3UO-Berkeley Lab unveil new nano-sized synthetic scaffolding technique 2Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 2Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 3Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 4Global Membrane Technology Market Will Reach $10,886.0 Million in 2019: Persistence Market Research 5Technology Applications International Corporation Subsidiary Enters Into Additional Exclusive Agreement with NASA at a Signing Ceremony at the Johnson Space Center In Houston, Texas 2Technology Applications International Corporation Subsidiary Enters Into Additional Exclusive Agreement with NASA at a Signing Ceremony at the Johnson Space Center In Houston, Texas 3
... that it,has received the European CE Mark (Conformite Europeene) ... CE Mark certifies,that the product has met EU health, ... Granted in the Netherlands, the,registration will allow the system ... countries around the world that recognize the CE Mark. ...
... Calif., Oct. 29 Cliniqa Corporation (San,Marcos, ... is pleased to,announce the acquisition of the ... Diego, CA), a wholly owned subsidiary of ... manufacturer of clinical,diagnostic products focusing on clinical ...
... to Focus on Sales Growth and Product ... BioLife Solutions,Inc. (OTC Bulletin Board: BLFS), a ... and cryopreservation media products for,cells, tissues, and ... product,manufacturing, warehousing, and customer order fulfillment to ...
Cached Biology Technology:Diamics Receives European CE Mark Approval for Its Pap-Map(TM) System for Cervical Cancer Screening 2Cliniqa Corporation Completes Asset Acquisition of Reagents Applications, Inc. 2BioLife Solutions Outsourcing Manufacturing, Warehousing, and Order Fulfillment to Bioserv Corporation 2BioLife Solutions Outsourcing Manufacturing, Warehousing, and Order Fulfillment to Bioserv Corporation 3