Navigation Links
Potential cure for captive amphibians with chytrid fungus
Date:5/12/2014

Researchers at Vanderbilt University have identified an alternative to a sometimes toxic therapy that protects frogs in zoos from a deadly fungal infection that has been destroying the amphibian populations worldwide. Their research is published ahead of print in Applied and Environmental Microbiology.

The fungal disease, chytridiomycosis, has been decimating frogs all over the world. At present, nothing can help amphibians in the wild, but zoos currently rely on the often-toxic itraconazole to eradicate the disease from infected amphibians they wish to acquire.

To preserve the most at risk amphibians, zoos have been acquiring "founding populations" of species threatened by chytridiomycosis, which is caused by the fungus, Batrachochytrium dendrobatidis.

"Some species, such as the Panamanian Golden Frog, are nearly extinct in nature, and doing well only in zoos," says Louise Rollins-Smith, a researcher on the study. "Facilities which house multiple amphibian species need safe treatments to protect their valuable colonies."

Brian Gratwicke, a conservation biologist with the National Zoo, describes the difficulties zoos face in treating the creatures. The animals must go through 10 days of immersion in an itraconazole solution.

"Itraconazole is a fairly expensive drug, and depending on the species we treat we can see a very high mortality rate," says Gratwicke. "An alternative treatment would be very helpful."

In the study, Rollins-Smith and colleagues, of Vanderbilt University, Nashville, TN, tested two potential alternatives, chloramphenicol, and amphotericin B. Although both drugs reduced B. dendrobatidis infection, neither could eradicate it. But amphotericin B had a critical advantage over chloramphenicol.

The investigators found that chloramphenicol can cause major changes in the community of microbes inhabiting amphibian skin, while amphotericin B does not, says Rollins-Smit
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mouse study points to potentially powerful tool for treating damaged hearts
2. Study yields potential drug targets for preeclampsia patients
3. RNA shows potential as boiling-resistant anionic polymer material for nanoarchitectures
4. UCI study finds modified stem cells offer potential pathway to treat Alzheimers disease
5. Scientists reveal potential link between brain development and breast cancer gene
6. Dartmouth researchers identify potential therapeutic target for deadly brain cancer
7. Scientists find potential drug targets in deadly pediatric brain tumors
8. Unzipping poplars biofuel potential
9. Crib mattresses emit potentially harmful chemicals, Cockrell School engineers find
10. Beer marinade could reduce levels of potentially harmful substances in grilled meats
11. New international partnership aims to unlock wheats potential
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... is available in French . ... just published in the prestigious Nature Neuroscience journal ... Centre of the Douglas Mental Health University Institute and McGill ... circuitry and dynamic mechanisms controlling memory as well of the ... sub-region named the subiculum. , In 2009, they developed ...
(Date:8/29/2014)... Until recently, little has been known about what ... international team of scientists, one of whom is a ... by showing that genes controlling the development of the ... rabbit domestication., The study was published Aug. 28 in ... questions. It is online at http://www.sciencemag.org/ ., The ...
(Date:8/29/2014)... type and number of connections in transcription factor networks ... in a study published in PLOS Computational Biology ... assortativity signature contributes to a network,s resilience against mutations. ... out-out assortativity of TFN models has a greater effect ... types of assortativity," said Dov A. Pechenick, PhD, lead ...
Breaking Biology News(10 mins):Memory and Alzheimer's: Towards a better comprehension of the dynamic mechanisms 2New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3Assortativity signatures of transcription factor networks contribute to robustness 2
... map data into BiblioSphere , Genomatix Software GmbH ... Science (AAAS) today announced an agreement that allows ... Environment into Genomatix's BibliospherePE pathway knowledge base and ... journal Science, developed the Signal Transduction Knowledge Environment, ...
... of a protein, human CD38, which may lead to important ... in almost every cellular process. The findings also may offer ... to diabetes and HIV-AIDS. , Levels of the ... human CD38 a marker for these diseases. , As ...
... at the National Institute of Child Health and Human ... parasite disperses from the red blood cells it infects. ... Development is one of the Institutes comprising the National ... September 20 Current Biology. , "This discovery provides the ...
Cached Biology News:Genomatix, AAAS ink agreement 2Protein structure key for AIDS, cell function 2Researchers discover how malaria parasite disperses from red blood cells 2Researchers discover how malaria parasite disperses from red blood cells 3
(Date:8/28/2014)... Aug. 28, 2014   SunTrust Robinson Humphrey ... veterans to its equity research team in biotechnology ... expansion in equity research demonstrates our commitment to ... to enhance their investment decision making," said ... "We continue to make significant investments in differentiated ...
(Date:8/28/2014)... , Aug. 28, 2014  Armetheon, Inc. ( ... novel mid- to late-stage cardiovascular drug candidates, today ... its first round of financing. The Series A ... Hercules Bioventures with participation from investors that included ... executive, Dr. Larry Hsu , the founder ...
(Date:8/28/2014)... Washington, USA (PRWEB) August 27, 2014 ... next month for SPIE Laser Damage 2014 ... optical materials for high-power lasers will run 14-17 September. ... society for optics and photonics . , The premier ... for understanding laser damage to optical materials will engage ...
(Date:8/28/2014)... 2014 Earlier this month, a ... partnership with the U.S. Air Force on the performance ... indicated that this type of fuel made from mustard ... be important to America’s Eco friendly future. In fact, ... mandate to become independent of foreign oil over the ...
Breaking Biology Technology:SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 3Armetheon Completes $7.0 Million Series A Financing 2Armetheon Completes $7.0 Million Series A Financing 3Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 4Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 5
... Software Inc., the leading,provider of web-based employee ... independent research firm Bersin & Associates ranked,Halogen ... its recent report on talent,management vendors. Halogen ... product strength, architecture and customer satisfaction., ...
... BioSeek, Inc. today,announced that Roy A. Whitfield ... of directors. Mr. Whitfield had joined BioSeek,s board ... the Company since November,2005., "Roy,s management experience ... been extraordinarily valuable to BioSeek thus,far. We look ...
... - Oncothyreon Inc. (Nasdaq:,ONTY) (TSX: ONY), a biotechnology ... for the treatment of cancer, today,announced the launch ... ., "We are excited about our new ... which provides additional information about our,product pipeline and ...
Cached Biology Technology:Halogen Receives High Ratings from Bersin & Associates - Company recognized as a market leader, and receives praise for outstanding customer satisfaction 2BioSeek Elects Roy Whitfield Executive Chairman of Board of Directors 2
... cyclin required for G1-phase progression and is ... cyclin D2 can phosphorylate pRB when associated ... Human, Mouse, and Rat. Others-not tested. ... suited for neutralization of cyclin D2 activity ...
Mouse Anti-Human Methyl-CpG binding domain protein 2 (MBD2 Monoclonal Antibody Family: Other Applications: Western Blot...
... Synthetic peptide corresponding ... Antigen Family: ... Antigen Subfamily: not ... Recommended Storage: Long ...
V beta 5 Purified Anti-Human clone MH3-2, Isotype Mouse IgG 2a , kappa, 0.1 mg Consult technical datasheet for details....
Biology Products: