Navigation Links
Potent spider toxin 'electrocutes' German, not American, cockroaches
Date:7/11/2014

Using spider toxins to study the proteins that let nerve cells send out electrical signals, Johns Hopkins researchers say they have stumbled upon a biological tactic that may offer a new way to protect crops from insect plagues in a safe and environmentally responsible way.

Their findingthat naturally occurring insect toxins can be lethal for one species and harmless for a closely related onesuggests that insecticides can be designed to target specific pests without harming beneficial species like bees. A summary of the research, led by Frank Bosmans, Ph.D., an assistant professor of physiology at the Johns Hopkins University School of Medicine, will be published July 11 in the journal Nature Communications.

"Most insecticides used today take a carpet-bombing approach, killing indiscriminately and sometimes even hurting humans and other animals," says Bosmans. "The more specific a toxin's target, the less dangerous it is for everything else."

Their finding began with the mistaken inclusion of a protein, called Dc1a, in a shipment sent by the team's Australian collaborators. The protein was extracted from the venom of the desert bush spider Diguetia canities, which lives in the deserts of the southwestern United States and Mexico and is harmless to humans.

When Bosmans' Australian collaborators tested the impact of Dc1a on proteins from American cockroaches, the proteins reacted very weakly, so they hadn't planned on sending Dc1a to Bosmans for further study. But it was accidentally included with other spider venom proteins for Bosmans' group to test, says Bosmans, so his laboratory did so.

The Bosmans lab studies proteins called sodium channels, which are found in the outer envelope of nerve cells throughout the body. Stimuli, like the acute pressure of hitting your finger with a hammer, are communicated to the proteins, causing them to open their pores so that sodium flows in. The positive charg
'/>"/>

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Epigenetic signatures direct the repair potential of reprogrammed cells
2. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
3. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
4. Researchers report potential for a moderate New England red tide in 2012
5. Gallbladder shown as potential stem cell source for regenerative liver and metabolic disease
6. Researchers find potential dark side to diets high in beta-carotene
7. Beehive extract shows potential as prostate cancer treatment
8. Gene therapy for hearing loss: Potential and limitations
9. Folic acid food enrichment potentially protective against childhood cancers
10. Nuisance seaweed found to produce compounds with biomedical potential
11. Potential new approach to regenerating skeletal muscle tissue
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Potent spider toxin 'electrocutes' German, not American, cockroaches
(Date:8/21/2014)... the water window? It consists of radiations in the ... by the water in biological tissues. New theoretical findings ... within the water window. These could be the basis ... of the biological samples or to be used in ... physical mechanism needed to efficiently generate the harmonic radiationswhich ...
(Date:8/21/2014)... A team of researchers at Louisiana Tech ... using affordable, consumer-grade 3D printers and materials ... contain antibacterial and chemotherapeutic compounds for targeted ... doctoral students and research faculty from Louisiana ... collaborated to create filament extruders that can ...
(Date:8/20/2014)... Aug. 20, 2014 George E. Fox, a John and ... of Houston (UH), was named a fellow in the International ... , Fox is one of four members two ... chosen as fellows in 2014. Fellows are elected every ... more than 500 members from more than 20 countries, the ...
Breaking Biology News(10 mins):Water window imaging opportunity 2Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3UH professor named fellow by International Astrobiology Society 2
... emphasizes the development of a series of nested environment ... with the individual, and also affect the development of ... is the major source influencing human development, which is ... saw the individual,s experience "as a set of nested ...
... N. Kuggie Vallee Foundation announces, today, the first recipients ... are: Dr. Kirsty L. Spalding, Senior Researcher in ... Karolinska Institutet (Stockholm, Sweden) who studies obesity by investigating ... David Tobin, Assistant Professor of Molecular Genetics and Microbiology ...
... enhance mental energy and well-being not only for healthy ... according to a July 15 panel discussion at the ... Food Expo held at McCormick Place. Bonnie Kaplan, ... University of Calgary, Alberta, Canada, said Monday vitamins and ...
Cached Biology News:
(Date:8/22/2014)... Researchers at the University of Surrey have discovered how ... the body,s clock genes. , The new study, published ... that this clock activity in turn regulates the cycle ... researchers also discovered that the local biological clock and ... importance of the clock in bladder physiology and ageing. ...
(Date:8/22/2014)... investigated for application as catalysts, sensors, drug ... in photonics and molecular electronics. Gaining knowledge ... physical and chemical properties, has been challenging. ... demonstrated that high-resolution electron microscopy can be ... which all gold atoms are observed. The ...
(Date:8/22/2014)... 2014 Research and Markets has ... Gel Permeation Chromatography (GPC) Industry Report 2014" report ... China Gel Permeation Chromatography (GPC) Industry Report is a ... the global gel permeation chromatography industry with a focus ... basic overview of the industry including definitions, classifications, applications ...
(Date:8/22/2014)... Nerium International, the go-to, buzzworthy ... spotlight again. Nerium will showcase its signature NeriumAD® ... Contouring Cream to Hollywood’s elite at the official ... 66th Primetime Emmy® Awards. , Developed from cutting-edge ... trials show that NeriumAD night cream dramatically reduces ...
Breaking Biology Technology:Treatment for overactive bladder and irritable bowel syndrome advanced through pioneering research 2A breakthrough in imaging gold nanoparticles to atomic resolution by electron microscopy 2Global and China Gel Permeation Chromatography (GPC) Industry Report 2014 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3
... , , STOCKHOLM , January ... the formation of BioChromix Pharma AB, a,new company working to develop ... Development will initially take,28 percent ownership in the new company. , ... as they have a novel,approach that targets the cause of the ...
... , FORT WORTH, Texas , ... Board: WNDM), announced today that it is nearing the completion of its ... first distributor in that country.  Numerous physicians in the nation have ... with its speed and efficacy in the management of diabetic ulcers ...
... , WILMINGTON, Del. , and ... DD ) and BASF Plant Science announced they have reached an ... DuPont and BASF filed suit against each other in U.S. Federal Court ... property rights relating to biotechnology traits, including traits that provide tolerance to ...
Cached Biology Technology:Karolinska Development Expands its Life Science Portfolio With BioChromix Pharma 2Karolinska Development Expands its Life Science Portfolio With BioChromix Pharma 3Wound Management Technologies, Inc. Rapidly Expands Its International Presence 2Wound Management Technologies, Inc. Rapidly Expands Its International Presence 3Wound Management Technologies, Inc. Rapidly Expands Its International Presence 4DuPont and BASF Announce Settlement 2DuPont and BASF Announce Settlement 3
... to reward the animal for foraging behavior.The Spatial ... built around a video camera, frame grabber, and ... fields at once and up to 6 moving ... records them, but also allows video replay of ...
tracking dye in electrophoresis; free acid, C 19 H 10 BrO 5 S; MW: 669.96...
... The Rice Oligo Microarray, 22K ... of rice genes associated with biological ... abiotic stress response. Each microarray contains ... of the rice (japonica) genome focuses ...
... Last innovation from Magnetofection technology, SilenceMag ... system available. Simple, rapid and easy ... and non toxic. Specifically designed for ... silencing at very low doses of ...
Biology Products: