Navigation Links
Potent spider toxin 'electrocutes' German, not American, cockroaches
Date:7/11/2014

Using spider toxins to study the proteins that let nerve cells send out electrical signals, Johns Hopkins researchers say they have stumbled upon a biological tactic that may offer a new way to protect crops from insect plagues in a safe and environmentally responsible way.

Their findingthat naturally occurring insect toxins can be lethal for one species and harmless for a closely related onesuggests that insecticides can be designed to target specific pests without harming beneficial species like bees. A summary of the research, led by Frank Bosmans, Ph.D., an assistant professor of physiology at the Johns Hopkins University School of Medicine, will be published July 11 in the journal Nature Communications.

"Most insecticides used today take a carpet-bombing approach, killing indiscriminately and sometimes even hurting humans and other animals," says Bosmans. "The more specific a toxin's target, the less dangerous it is for everything else."

Their finding began with the mistaken inclusion of a protein, called Dc1a, in a shipment sent by the team's Australian collaborators. The protein was extracted from the venom of the desert bush spider Diguetia canities, which lives in the deserts of the southwestern United States and Mexico and is harmless to humans.

When Bosmans' Australian collaborators tested the impact of Dc1a on proteins from American cockroaches, the proteins reacted very weakly, so they hadn't planned on sending Dc1a to Bosmans for further study. But it was accidentally included with other spider venom proteins for Bosmans' group to test, says Bosmans, so his laboratory did so.

The Bosmans lab studies proteins called sodium channels, which are found in the outer envelope of nerve cells throughout the body. Stimuli, like the acute pressure of hitting your finger with a hammer, are communicated to the proteins, causing them to open their pores so that sodium flows in. The positive charg
'/>"/>

Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Epigenetic signatures direct the repair potential of reprogrammed cells
2. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
3. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
4. Researchers report potential for a moderate New England red tide in 2012
5. Gallbladder shown as potential stem cell source for regenerative liver and metabolic disease
6. Researchers find potential dark side to diets high in beta-carotene
7. Beehive extract shows potential as prostate cancer treatment
8. Gene therapy for hearing loss: Potential and limitations
9. Folic acid food enrichment potentially protective against childhood cancers
10. Nuisance seaweed found to produce compounds with biomedical potential
11. Potential new approach to regenerating skeletal muscle tissue
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Potent spider toxin 'electrocutes' German, not American, cockroaches
(Date:7/23/2014)... The drought that has the entire country in its grip ... may also be responsible for the proliferation of a heat-loving ... rivers and hot springs, which the drought has made warmer ... died of an infection caused by this parasite after swimming ... the nose of an individual and travels to the brain. ...
(Date:7/23/2014)... The planet,s soil releases about 60 billion tons of ... more than that released by burning fossil fuels. This ... release of carbon is balanced by carbon coming into ... matter, as well as by the underground activities of ... that rising temperatures increase the rate of soil respiration. ...
(Date:7/23/2014)... fly Chrysomya megacephala is commonly found in ... determine the time of death, referred to as the ... of C. megacephala from Tamil Nadu is ... and molecular characterization through generation of DNA barcoding. This ... open access Biodiversity Data Journal . , ...
Breaking Biology News(10 mins):Diseases of another kind 2Climate change and the soil 2Dead body feeding larvae useful in forensic investigations 2
... general in a bunker. Floating in its bubble of cerebrospinal ... so the only way for the brain to observe, comprehend, ... information it receives. This information comes to it through a ... organs like the eye, ear, nose, and mouth. , In ...
... Ariadne Genomics, Inc. today announced the release ... analysis of biological pathways and gene regulation ... pharmaceutical companies. PathwayStudio?Central is available for a ... PathwayStudio?Central builds pathways from microarray data, identifies ...
... goal to reduce sickness and death from infections that ... on identifying ways to reduce the problem at its ... ice cubes or to rinse medical equipment is increasingly ... may contribute to many of these life-threatening infections. , ...
Cached Biology News:Molecular thermometers on skin cells detect heat and camphor 2Molecular thermometers on skin cells detect heat and camphor 3Molecular thermometers on skin cells detect heat and camphor 4Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis 2Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST) 2Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST) 3
(Date:7/24/2014)... 24, 2014 Three companies from the ... Livestrong’s Big C Competition. Out of 700 competition entrants, ... to the semi-final round. In this round twenty teams ... program, complete with mentoring from thought-leaders and medical entrepreneurs ... of the angelMD commitment to the Livestrong vision around ...
(Date:7/24/2014)... 24, 2014 2014 Deep Research ... is a professional and in-depth research report on ... Sulphate basic information, including its definition, classification, ... This research covers the international market analysis, including ... analysis covering macroeconomic environment & economic situation analysis, ...
(Date:7/24/2014)... Mich. , July 24, 2014  Neogen Corporation ... that future forecasts of its potential revenue from new ... call to investors and analysts on July 22, 2014, ... by analysts regarding this research. "It was ... questions about the potential of a new type of ...
(Date:7/24/2014)... July 24, 2014 WIRB-Copernicus Group ® ... and ethical review services for clinical research, announced ... a division of Richmond, VA ... biosafety and biosecurity consulting firm in ... WCG,s biosafety division – WCG Biosafety™ – will ...
Breaking Biology Technology:3 angelMD Startups Make Livestrong Big C Semi-finals 2Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 2Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 3Potassium Sulphate Market & SHMP Industry 2014 (Global, China) Analysis Now Available at DeepResearchReports.com 4Neogen comments on SenesTech 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 2WIRB-Copernicus Group Announces Acquisition of Alliance Biosciences; Executives Join WCG Biosafety Division 3
... 18 BioDuro & The National Center for,Safety ... announce their,receipt of full AAALAC accreditation. BioDuro and ... animal DMPK for clients worldwide., Dean Rodwell, ... operating under this standard for over a year, ...
... (BCI), a,biopharmaceutical company utilizing its platform technology to ... new neurons for the treatment,of central nervous system ... $20 million in an extension of its Series ... investor, New Enterprise Associates (NEA),along with current investors ...
... Anthera Pharmaceuticals,Inc., a privately held biopharmaceutical company ... and,collaborators have released data from the Varespladib ... Thrombosis, and Vascular,Biology (ATVB) Annual Conference in ... has completed Phase II trials in Varespladib ...
Cached Biology Technology:BioDuro & The National Center for Safety Evaluation of Drugs Received Full AAALAC Accreditation 2REVISED: BrainCells Inc. Expands Series B Financing to $50 Million 2Anthera Presents Data on Varespladib at ATVB Meeting 2
... MasterAmp™ Taq DNA Polymerase is a ... aquaticus. Having optimal activity at temperatures ... thermostable enzyme used for PCR and ... purpose. The enzyme has an intrinsic ...
... 4100 high pressure dual piston pump and the ... and utra low drift. The WaveQuest ... detection and provides superior stability. Hence ... and for monitoring to the highest of sensitivities. ...
Rabbit anti Xanthine Oxidase Xanthine Oxidase, Bovine Buttermilk...
... This CLS number ... number, created to easily ... If showing no availability ... the old Sigma-Aldrich number ...
Biology Products: