Navigation Links
Pneumonia revealed in a cough
Date:6/27/2013

A new method, which analyzes the sounds in a child's cough, could soon be used in poor, remote regions to diagnose childhood pneumonia reliably. According to Udantha Abeyratne from the University of Queensland in Australia and colleagues, this simple technique of recording coughs with a microphone on the patient's bedside table, has the potential to revolutionize the management of childhood pneumonia in remote regions around the world. Their work is published online in Springer's journal Annals of Biomedical Engineering.

Pneumonia is the leading killer of young children around the world. Since it is largely a disease of poverty, the vast majority of deaths occur in resource-poor regions such as sub-Saharan Africa, South Asia and remote areas of China. The lack of laboratory testing facilities and trained healthcare personnel in these regions mean difficulties in the timely diagnosis and adequate treatment of childhood pneumonia.

At the moment, community workers in these regions use the World Health Organization's simple clinical algorithm to diagnose pneumonia. However there are some limitations, including the high rate of false positive results which lead to over-prescription of rare antibiotic stocks.

Abeyratne and team's work identifies an easy-to-use alternative that addresses these challenges, in the form of new technology which analyzes cough sounds to diagnose pneumonia. Indeed, cough is a main symptom of pneumonia and carries vital information on the lower respiratory tract - consolidation of the lungs and secretions in particular. These markers of infection alter the acoustic properties of coughs helping to identify pneumonia-specific features.

The researchers analyzed 815 cough events recorded from a total of 91 hospitalized children with and without pneumonia, at the Sardjito Hospital of Gadjah Mada University in Indonesia. Cough sounds were collected by microphones placed on nearby bedside tables. Coughs were classified as either pneumonic or non-pneumonic. The researchers used the overall clinical diagnosis provided by pediatric respiratory clinicians - aided with routine diagnostic technologies - to validate the sound analysis. From the analysis of cough sounds alone, this new technique was able to identify pneumonia cases with over 90 percent sensitivity, meaning that it identifies most patients who actually have pneumonia. In addition, it did so with a low false positive rate, outperforming the existing WHO algorithm for resource-poor regions.

The authors conclude: "Our results indicate the feasibility of taking a cough-centered approach to the diagnosis of childhood pneumonia in resource-poor regions. The technology, in its simplest version, will require between 5-10 cough sounds and will automatically and immediately provide a diagnosis without requiring physical contact with patients. Such a system, if successful, is expected to be a paradigm-shifting novelty in the field of pneumonia diagnosis in remote regions."


'/>"/>

Contact: Sophia Grein
sophia.grein@springer.com
49-622-148-78414
Springer
Source:Eurekalert

Related biology news :

1. Ceramic indoor cookstove use did not significantly lower child pneumonia risk in rural Kenya
2. Scientists sequence genome of pathogen responsible for pneumocystis pneumonia
3. Stopping smoking reduces risk of bacterial pneumonia in people with HIV
4. Low vitamin D levels a risk factor for pneumonia
5. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
6. Ancient giant turtle fossil revealed
7. Key part of plants rapid response system revealed
8. Detector of DNA damage: Structure of a repair factor revealed
9. Mystery of elephant infrasounds revealed
10. The genetic cause of a severe skeletal disease in Brazilian Terrier puppies revealed
11. Bread wheats large and complex genome is revealed
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2016)... --  EyeLock LLC , a market leader of iris-based ... IoT Center of Excellence in Austin, Texas ... embedded iris biometric applications. EyeLock,s iris authentication ... with unmatched biometric accuracy, making it the most proven ... platform uses video technology to deliver a fast and ...
(Date:4/28/2016)... First quarter 2016:   , ... the first quarter of 2015 The gross margin was ... 18.8) and the operating margin was 40% (-13) Earnings ... flow from operations was SEK 249.9 M (21.2) , ... SEK 7,000-8,500 M. The operating margin for 2016 is ...
(Date:4/15/2016)... , April 15, 2016 ... "Global Gait Biometrics Market 2016-2020,"  report to their ... ) , ,The global gait biometrics market ... 13.98% during the period 2016-2020. Gait ... which can be used to compute factors that ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Sequenom, Inc. (NASDAQ: ... enabling healthier lives through the development of innovative products ... the United States denied its ... the claims of Sequenom,s U.S. Patent No. 6,258,540 (",540 ... criteria established by the Supreme Court,s Mayo Collaborative Services ...
(Date:6/27/2016)... -- Liquid Biotech USA , Inc. ... Research Agreement with The University of Pennsylvania ("PENN") ... patients.  The funding will be used to assess ... outcomes in cancer patients undergoing a variety of ... to support the design of a therapeutic, decision-making ...
(Date:6/24/2016)... ... 24, 2016 , ... Researchers at the Universita Politecnica delle Marche in Ancona ... or pleural mesothelioma. Their findings are the subject of a new article on the ... are signposts in the blood, lung fluid or tissue of mesothelioma patients that can ...
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
Breaking Biology Technology: