Navigation Links
Pneumonia revealed in a cough
Date:6/27/2013

A new method, which analyzes the sounds in a child's cough, could soon be used in poor, remote regions to diagnose childhood pneumonia reliably. According to Udantha Abeyratne from the University of Queensland in Australia and colleagues, this simple technique of recording coughs with a microphone on the patient's bedside table, has the potential to revolutionize the management of childhood pneumonia in remote regions around the world. Their work is published online in Springer's journal Annals of Biomedical Engineering.

Pneumonia is the leading killer of young children around the world. Since it is largely a disease of poverty, the vast majority of deaths occur in resource-poor regions such as sub-Saharan Africa, South Asia and remote areas of China. The lack of laboratory testing facilities and trained healthcare personnel in these regions mean difficulties in the timely diagnosis and adequate treatment of childhood pneumonia.

At the moment, community workers in these regions use the World Health Organization's simple clinical algorithm to diagnose pneumonia. However there are some limitations, including the high rate of false positive results which lead to over-prescription of rare antibiotic stocks.

Abeyratne and team's work identifies an easy-to-use alternative that addresses these challenges, in the form of new technology which analyzes cough sounds to diagnose pneumonia. Indeed, cough is a main symptom of pneumonia and carries vital information on the lower respiratory tract - consolidation of the lungs and secretions in particular. These markers of infection alter the acoustic properties of coughs helping to identify pneumonia-specific features.

The researchers analyzed 815 cough events recorded from a total of 91 hospitalized children with and without pneumonia, at the Sardjito Hospital of Gadjah Mada University in Indonesia. Cough sounds were collected by microphones placed on nearby bedside tables. Coughs were classified as either pneumonic or non-pneumonic. The researchers used the overall clinical diagnosis provided by pediatric respiratory clinicians - aided with routine diagnostic technologies - to validate the sound analysis. From the analysis of cough sounds alone, this new technique was able to identify pneumonia cases with over 90 percent sensitivity, meaning that it identifies most patients who actually have pneumonia. In addition, it did so with a low false positive rate, outperforming the existing WHO algorithm for resource-poor regions.

The authors conclude: "Our results indicate the feasibility of taking a cough-centered approach to the diagnosis of childhood pneumonia in resource-poor regions. The technology, in its simplest version, will require between 5-10 cough sounds and will automatically and immediately provide a diagnosis without requiring physical contact with patients. Such a system, if successful, is expected to be a paradigm-shifting novelty in the field of pneumonia diagnosis in remote regions."


'/>"/>

Contact: Sophia Grein
sophia.grein@springer.com
49-622-148-78414
Springer
Source:Eurekalert

Related biology news :

1. Ceramic indoor cookstove use did not significantly lower child pneumonia risk in rural Kenya
2. Scientists sequence genome of pathogen responsible for pneumocystis pneumonia
3. Stopping smoking reduces risk of bacterial pneumonia in people with HIV
4. Low vitamin D levels a risk factor for pneumonia
5. Genetic mutation depicted in van Goghs sunflower paintings revealed by scientists
6. Ancient giant turtle fossil revealed
7. Key part of plants rapid response system revealed
8. Detector of DNA damage: Structure of a repair factor revealed
9. Mystery of elephant infrasounds revealed
10. The genetic cause of a severe skeletal disease in Brazilian Terrier puppies revealed
11. Bread wheats large and complex genome is revealed
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... , April 15, 2016 ... the,  "Global Gait Biometrics Market 2016-2020,"  report to ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) , ,The global gait biometrics ... of 13.98% during the period 2016-2020. ... angles, which can be used to compute factors ...
(Date:4/13/2016)...  IMPOWER physicians supporting Medicaid patients in ... standard in telehealth thanks to a new partnership with ... IMPOWER patients can routinely track key health measurements, such ... and, when they opt in, share them with IMPOWER ... local retail location at no cost. By leveraging this ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys has ... CEO, Barrett Bready , M.D., who returned to ... the original technical leadership team, including Chief Technology Officer, ... Product Development, Steve Nurnberg and Vice President of Software ... the company. Dr. Bready served as CEO ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... 2016 , ... Supplyframe, the Industry Network for electronics hardware ... . Located in Pasadena, Calif., the Design Lab’s mission is to bring together ... built and brought to market. , The Design Lab is Supplyframe’s physical representation ...
(Date:6/23/2016)... June 23, 2016  Blueprint Bio, a company dedicated ... the medical community, has closed its Series A funding ... . "We have received a commitment from ... we need to meet our current goals," stated ... the runway to complete validation on the current projects ...
(Date:6/23/2016)... ... June 23, 2016 , ... Regulatory Compliance Associates® Inc. (RCA), ... free webinar on Performing Quality Investigations: Getting to Root Cause. ... no charge. , Incomplete investigations are still a major concern to the Regulatory ...
(Date:6/22/2016)... 2016 Cell Applications, Inc. and StemoniX ... produce up to one billion human induced pluripotent ... week. These high-quality, consistent stem cells enable researchers ... spend more time doing meaningful, relevant research. This ... manufacturing process that produces affordable, reliable HiPSC for ...
Breaking Biology Technology: