Navigation Links
Photonic crystal biosensors detect protein-DNA interactions
Date:9/23/2008

thought to be responsible for the maintenance of resistance-encoding plasmids in certain infectious bacteria. The second was the human apoptosis-inducing factor (AIF), a protein that binds to chromosomal DNA in a DNA-sequence-independent manner.

The photonic crystal biosensor technology was further utilized in a screen for inhibitors of the AIF-DNA interaction, and through this screen aurin tricarboxylic acid was identified as the first in vitro inhibitor of AIF.

"Aurin tricarboxylic acid displayed about 80 percent inhibition of AIF-DNA binding," Hergenrother said. "Aurin tricarboxylic acid was the only compound to exhibit significant inhibition out of approximately 1,000 compounds screened."

While the photonic crystal biosensor was demonstrated only for protein-DNA interactions, analogous experiments with protein-RNA interactions, and protein-protein interactions are also possible, Cunningham said. "We also could grow cancer cells on the photonic crystal surface, and see how different drugs affect cell growth."


'/>"/>

Contact: James E. Kloeppel
kloeppel@uiuc.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert

Page: 1 2

Related biology news :

1. The photonic beetle
2. Scientists demonstrate the sharpest measurement of ice crystals in clouds
3. Crystal (eye) ball: Study says visual system equipped with future seeing powers
4. New clues to how proteins dissolve and crystallize
5. Scientists find missing evolutionary link using tiny fungus crystal
6. Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth
7. Unveiling the structure of microcrystals
8. Researchers develop liquid crystal pharmaceuticals to fight cancer and other diseases
9. Enzyme detectives uncover new reactions, products
10. Researchers study facial structures, brain abnormalities to reveal formula for detection of autism
11. Best code for disease detection, bar none
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... YORK , June 24, 2015 The ... rate. The major drivers for the market include growth ... number of new drug launches. Over the years, the ... increased. Between 2001 and 2010, the FDA approved 225 ... according to WIPO, Europe accounted ...
(Date:6/24/2015)... , June 22, 2015 ... the addition of the "Huawei Ascend Mate ... report to their offering. Huawei,s technological ... the opposite direction than Apple,s and Samsung,s one. ... sensor developed by Fingerprint Cards, a main actor ...
(Date:6/23/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/vq2k2f/bodyworn ... "Body-Worn Temperature Sensors Market - Global Industry Analysis, ... 2020" report to their offering. ... body-worn temperature sensors market. The global body-worn temperature ... of types, care setting, patient demographic, applications and ...
Breaking Biology News(10 mins):Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2Body-Worn Temperature Sensors Market - Global Industry Analysis 2
... brain, but they also leave behind in the bloodstream a ... the future to direct better treatment for schizophrenia and other ... study is among the first to use metabolomics -- the ... processes -- to look at a psychiatric disease and its ...
... Research Institute on Addictions (RIA) is investigating the “brain’s ... stress, stress-related behavior and anxiety. , A five-year, $1.7 ... is supporting this investigation. , “It is widely ... use and abuse marijuana is to relieve stress,?according to ...
... generators (dopaminergics) in brain cells has produced improvement in ... tests carried out with monkeys by the Navarra University ... at the Hospital and at the other Navarra University-based ... , The results have been published in the latest ...
Cached Biology News:Chemical maps hint at drug's effects on schizophrenia 2Chemical maps hint at drug's effects on schizophrenia 3Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys 2Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys 3
(Date:7/1/2015)... BANGALORE, India , July 1, 2015 ... that uses next generation sequencing technology to empower cancer ... Storrer as chief executive officer. In his expanded ... responsible for all strategy, business expansion and worldwide operations ... served as Strand,s chairman and CEO since its founding ...
(Date:7/1/2015)... , July 1, 2015  Axovant Sciences ... focused on the treatment of dementia, today announced ... on July 22 at 5:45 p.m. EDT following ... Alzheimer,s Association International Conference 2015 (AAIC). ... , Dr. Lawrence Friedhoff , ...
(Date:7/1/2015)... ... ... A newly launched business plan contest will ask startup companies from around the ... R&D. The Pistoia Alliance President’s Startup Challenge 2015 will see small and medium enterprises ... mentorship from a senior industry figure drawn from the Pistoia Alliance membership. , The ...
(Date:7/1/2015)... ... , ... Apex Therapeutics announced today that company CEO, David Broecker provided a ... The presentation took place on Tuesday, June 16 and provided an update on the ... the treatment of pancreatic cancer. A copy of the company overview can be ...
Breaking Biology Technology:Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 2Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 3Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3Pistoia Alliance Launches Startup Challenge 2Pistoia Alliance Launches Startup Challenge 3Apex Therapeutics Presented Company Overview at This Year’s BIO International Convention in Philadelphia, PA 2
... AMN Healthcare Services,Inc. (NYSE: AHS ), the ... its quarterly conference call to discuss second quarter,results on ... The,company expects to issue an earnings news release also ... Time., A live webcast of the call can ...
... Management and New Leaf Venture Partners Commit To Purchase ... Subsidiary of $200 to $300 Million ... to Reduce Angiotech Debt, VANCOUVER, July 7 /PRNewswire-FirstCall/ ... a global specialty pharmaceutical and,medical device company, today announced ...
... July 4 ,Shire Limited (LSE:SHP, NASDAQ: SHPGY), the global ... 31 July 2008, Results press release will ... 07:00 EDT Investor meeting and conference call time: ... Analyst meeting and conference call:, Angus Russell, Chief ...
Cached Biology Technology:AMN Healthcare Services to Host 2008 Second Quarter Earnings Conference Call on Wednesday, August 6, 2008 2Angiotech to Establish Separate Operating and Royalty Businesses 2Angiotech to Establish Separate Operating and Royalty Businesses 3Angiotech to Establish Separate Operating and Royalty Businesses 4Angiotech to Establish Separate Operating and Royalty Businesses 5Angiotech to Establish Separate Operating and Royalty Businesses 6Angiotech to Establish Separate Operating and Royalty Businesses 7Angiotech to Establish Separate Operating and Royalty Businesses 8Angiotech to Establish Separate Operating and Royalty Businesses 9Angiotech to Establish Separate Operating and Royalty Businesses 10Angiotech to Establish Separate Operating and Royalty Businesses 11Angiotech to Establish Separate Operating and Royalty Businesses 12Angiotech to Establish Separate Operating and Royalty Businesses 13Angiotech to Establish Separate Operating and Royalty Businesses 14Shire Ltd - Second Quarter 2008 Results Date Notification - 31 July 2008 2
Request Info...
2 ml SmartScan Racks...
Leptin Receptor Polyclonal Ab 100 ug purified rabbit anti-mouse Leptin Receptor. Tested in Western blotting....
... The EC135-90 is a compact, highly versatile ... volts and 500 milliamps, this power supply is ... gels as well as all types of small ... in constant voltage or constant current with a ...
Biology Products: