Navigation Links
Phage hunting students publish in PLoS ONE
Date:4/25/2011

Recently a research paper titled "Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution" was published in PLoS ONE, a peer-reviewed online journal published by the Public Library of Science.

The authors included 12 Washington University undergraduates who had participated as freshman in the inaugural Phage Hunters course at Washington University in St. Louis.

Phages are viruses that infect bacteria by injecting genetic material into them with a syringe-like plunger. In fact, they even look rather like outlandish syringes.

Phage Hunting

Phage Hunters is a freshman focus course the biology department first offered in 2008. The course, which is supported by the Science Education Alliance at the Howard Hughes Medical Institute, offers freshmen a research experience, isolating and characterizing novel phages.

Starting in the fall semester, students collect soil samples, and isolate phages from the soil. Once isolated, students purify and characterize the phage. Nearly all the phages isolated in this way are new to science.

Over winter break the DNA genomes of several phages are sequenced, and in the spring semester students analyze the sequence information to get an in-depth picture of how their phage works and relates genetically to other previously characterized phages.

"A critical part of science education is helping students learn to 'think like a scientist,' said Sarah C. Elgin, PhD, the Viktor Hamburger Distinguished Professor in Arts & Sciences, who taught the class. "This course requires students to do just that, giving them new analytical skills and a new perspective. Plus, they have a lot of ownership of the project it is their phage something that no one else has studied. Discovery is a real thrill!."

More on Phages

Phage are the most numerous "biological entities" in the world (they have to be called entities because no
'/>"/>

Contact: Diana Lutz
dlutz@wustl.edu
314-935-5272
Washington University in St. Louis
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. H. Pylori bacteria may help prevent some esophageal cancers
2. Genetic predictors of esophageal cancer identified
3. New study overturns orthodoxy on how macrophages kill bacteria
4. University of Saskatchewan and Canadian Synchrotron researchers shed light on esophageal disease
5. Macrophages: The defense cells that help throughout the body
6. Researchers describe first functioning lipidome of mouse macrophage
7. Effect of 6 mT SMF on phagocytosis depends on macrophage differentiation degree
8. Esophageal cancer risk lower than expected for patients with GERD
9. Pitt researchers describe molecular 2-step leading to protein clumps of Huntingtons disease
10. New therapeutic strategy could target toxic protein in most patients with Huntingtons disease
11. Small molecules might block mutant protein production in Huntingtons disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2015)... 25, 2015  TAKE Solutions Ltd., a global business ... United States Patent and Trademark Office (USPTO) for its ... TAKE Solutions, Clinical Accelerators to reduce the time taken ... to standardization without the accelerators), thus reducing time to ... At the heart of the patented Clinical Data ...
(Date:6/24/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... announced that Sharp has selected its industry-leading Natural ... its latest flagship smartphone device, the AQUOS ZETA ... shipments of its fingerprint ID sensor technology, this ... and leadership in the biometrics market through its ...
(Date:6/23/2015)... Minn. , June 23, 2015   ... company that supports the entire spectrum of clinical ... iMedNet ™ , the company,s intuitive, ... been awarded a Silver 2015 Stevie® Award by ... Health Products & Services Website category.  The American ...
Breaking Biology News(10 mins):TAKE Solutions Awarded Patent By USPTO 2Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2
... URBANA - A tool commonly used by financial strategists ... stock portfolio was used to develop a diversified portfolio of ... purposes given the uncertainty about climate change. Instead of ... a stock, University of Illinois environmental economist Amy Ando and ...
... WEST LAFAYETTE, Ind. - The brown tissue that signals ... large producers and home gardeners, but a Purdue University researcher ... the disease sitting on a shelf for 20 years. ... transgenic tomato with a thicker juice that yields 10 percent ...
... A new initiative aims to build a grand tree of ... living things are related, from the tiniest bacteria to the ... for more than 150 years, ever since Charles Darwin drew ... in fleshing out the major branches of the tree of ...
Cached Biology News:Financial tool considered climate change uncertainty to select land for conservation 2Financial tool considered climate change uncertainty to select land for conservation 3Blossom end rot plummets in Purdue-developed transgenic tomato 2Researchers aim to assemble the tree of life for all 2 million named species 2Researchers aim to assemble the tree of life for all 2 million named species 3
(Date:7/27/2015)... YORK , July 27, 2015 ... today announced the winners of its annual Klerman ... research by scientists who have been supported by ... career scientists to pursue innovative ideas in neurobiological ... "proof" of concept for the early detection, treatment, ...
(Date:7/25/2015)... ... ... Technology leader Anton Paar offers the Abbemat T-Check ... of the measuring prism. This is required to achieve the most precise refractive ... requirements. It is likely that no refractometer manufacturers on the market can traceably ...
(Date:7/24/2015)... DIEGO , July 24, 2015 Orexigen ... and financial results for the second quarter 2015 on ... announcement, Orexigen will provide a business update and discuss ... call at 8:00 a.m. Eastern Time (5:00 a.m. Pacific ... by phone by calling (800) 447-0521 (domestic) or (847) ...
(Date:7/23/2015)... , July 23, 2015 ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") ... financial results for the second quarter 2015 on Thursday, August ... call and webcast on that day at 5:00 pm ET ... a business update. The call will be hosted by ... , , , LIVE CALL: , , ...
Breaking Biology Technology:Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 2Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 3Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 4Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 5Brain & Behavior Research Foundation Names Winners of Klerman-Freedman Prizes for Exceptional Research 6It’s T-Time for Refractometers: On-site Temperature Check Now Available 2ImmunoCellular Therapeutics to Report Second Quarter 2015 Financial Results on August 6, 2015 2
... , , INCLINE VILLAGE, Nev., Sept. 18 ... an adjustment to the conversion rate for its 2.00% Convertible Senior Notes ... 94.447 shares of common stock per $1,000 principal amount of the Notes, ... 89.165 shares of common stock per $1,000 principal amount of the Notes. ...
... , 10 Years of Planning for Unique Reefs ... CHARLESTON, S.C., Sept. 18 Environmental Defense Fund saluted the ... protect what may be Earth,s largest deepwater coral ecosystem off the ... A veritable wonderland of marine life, the 25,000-square-mile area is among ...
... , TUSTIN, Calif., Sept. 18 AMDL ... in China, announced today its stockholders have approved by verbal consent the ... Corporation" . The new ticker symbol on the New York ... Company has filed an amendment to its ,Articles of Incorporation, to implement ...
Cached Biology Technology:PDL BioPharma Announces Conversion Rate Adjustment for Its 2.00% Convertible Senior Notes Due February 15, 2012 2Big Win for Huge Coral Reefs off NC, SC, Georgia, Florida 2AMDL Inc. Announces Stockholder Approval of Name Change and Issuance of a New Trading Symbol on the NYSE Alternext US 2AMDL Inc. Announces Stockholder Approval of Name Change and Issuance of a New Trading Symbol on the NYSE Alternext US 3AMDL Inc. Announces Stockholder Approval of Name Change and Issuance of a New Trading Symbol on the NYSE Alternext US 4AMDL Inc. Announces Stockholder Approval of Name Change and Issuance of a New Trading Symbol on the NYSE Alternext US 5
... ChipWriter Pro system, 220-240 V, uses floating ... oligonucleotides, carbohydrates, lipids, and other biomolecules onto ... This system can generate high-density arrays with ... or greater than 57,000 spots per membrane ...
... ProteinChip arrays have been developed for ... samples. A variety of ProteinChip chemical ... according to their unique biochemical properties. ... allowing side-by-side sample comparison, and the ...
The SmartSpec printer paper is used to record data generated by the SmartSpec Plus spectrophotometer. Supplied as 5 packs....
... been developed for affinity capture of ... of ProteinChip chemical surfaces allow differential ... unique biochemical properties. Each chip has ... comparison, and the chips are color-coded ...
Biology Products: