Navigation Links
Peering into living cells -- without dye nor fluophore
Date:2/7/2013

In the world of microscopy, this advance is almost comparable to the leap from photography to live television. Two young EPFL researchers, Yann Cotte and Fatih Toy, have designed a device that combines holographic microscopy and computational image processing to observe living biological tissues at the nanoscale. Their research is being done under the supervision of Christian Depeursinge, head of the Microvision and Microdiagnostics Group in EPFL's School of Engineering.

Using their setup, three-dimensional images of living cells can be obtained in just a few minutes instantaneous operation is still in the works at an incredibly precise resolution of less than 100 nanometers, 1000 times smaller than the diameter of a human hair. And because they're able to do this without using contrast dyes or fluorescents, the experimental results don't run the risk of being distorted by the presence of foreign substances.

Being able to capture a living cell from every angle like this lays the groundwork for a whole new field of investigation. "We can observe in real time the reaction of a cell that is subjected to any kind of stimulus," explains Cotte. "This opens up all kinds of new opportunities, such as studying the effects of pharmaceutical substances at the scale of the individual cell, for example."

Watching a neuron grow

This month in Nature Photonics the researchers demonstrate the potential of their method by developing, image by image, the film of a growing neuron and the birth of a synapse, caught over the course of an hour at a rate of one image per minute. This work, which was carried out in collaboration with the Neuroenergetics and cellular dynamics laboratory in EPFL's Brain Mind Institute, directed by Pierre Magistretti, earned them an editorial in the prestigious journal. "Because we used a low-intensity laser, the influence of the light or heat on the cell is minimal," continues Cotte. "Our technique th
'/>"/>

Contact: Yann Cotte
yann.cotte@epfl.ch
41-216-937-012
Ecole Polytechnique Fdrale de Lausanne
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Protecting living fossil trees
2. Global Surgical Devices Market Growth Driven by Improving Standards of Living and Longer Life Expectancies, Research Shows
3. Molecular spectroscopy tracks living mammalian cells in real time as they differentiate
4. Nature: Microscope looks into cells of living fish
5. Living microprocessor tunes in to feedback
6. Photograph of a living human brain is the overall winner of Wellcome Image Awards 2012
7. Penn researchers improve living tissues with 3-D printed vascular networks made from sugar
8. Force of nature: Defining the mechanical mechanisms in living cells
9. A new look at proteins in living cells
10. Living power cables discovered
11. Watching the cogwheels of the biological clock in living cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Peering into living cells -- without dye nor fluophore
(Date:7/30/2014)... Antonio Life Sciences Institute (SALSI), a joint venture between ... The University of Texas Health Science Center at San ... Pilot Program. The winners, Emily Boice from UTSA and ... $25,000 for their project titled, "Novel engineered ferritins for ... , Boice and Huang,s research is focused on finding ...
(Date:7/30/2014)... baboons suggests that the route to a higher rank is ... of supportive sisters. , A female baboon,s social status is ... of her mother - the higher the mother is ranked, ... rank in female baboons is thought to be determined at ... spot in the pecking order, whereas females born to low-ranking ...
(Date:7/30/2014)... University associate professor Andrew S. Mount, performed cutting-edge research ... for novel anti-fouling paint for ships and boats and ... The team,s findings, published in Nature Communications ... that attaches to a wide variety of surfaces using ... an underwater heavy-duty adhesive. , "In previous research, we ...
Breaking Biology News(10 mins):Supportive moms and sisters boost female baboon's rank 2Supportive moms and sisters boost female baboon's rank 3Study: Marine pest provides advances in maritime anti-fouling and biomedicine 2
... PHILADELPHIA The second American Association for Cancer ... Research: From the Laboratory to the Clinic provides attendees ... in a variety of fields, including the tumor microenvironment, ... takes place March 7-10, 2010, at the King Hussein ...
... of America is pleased to announce the 2010 Yeast ... at the University of British Columbia (UBC) in Vancouver, ... various aspects of eukaryotic biology in yeast. Program ... Canadian astronaut who is also a Member of Parliament. ...
... Texas Imagine a mosquito-borne virus that has already infected ... Asia, the islands of the Indian Ocean, Africa and northern ... that can linger for months or even years. It,s capable ... much of North America. And no vaccine or treatment exists ...
Cached Biology News:The AACR to host second cancer research conference in Jordan 22010 Yeast Genetics and Molecular Biology Meeting 22010 Yeast Genetics and Molecular Biology Meeting 3Experimental vaccine protects monkeys against chikungunya 2
(Date:7/31/2014)... AZ (PRWEB) July 31, 2014 Sales ... availability of its online sales training course – ... improve their sales performance. , Drawn from proven sales ... 500 companies, Mastering the Complex Sale online sales training ... to anyone who has face-to-face contact with customers, like ...
(Date:7/30/2014)... PARIS , July 30, 2014 /PRNewswire/ ... and NYSE: SNY) today announced that the Companies intend ... rare pediatric disease priority review voucher in connection with ... priority review voucher entitles the holder to designate a ... 6-month review from the filing date instead of the ...
(Date:7/30/2014)... , July 30, 2014  Decision Resources Group ... medical directors in the United States ... biosimilar market penetration will be the level of ... and the expected lower cost to patients. Payers ... that meet their pricing expectations in order to ...
(Date:7/30/2014)... 30, 2014  The Chicago Bears are excited to ... Dermatology (Academy) in an effort to raise awareness of ... host free SPOT me™ skin cancer screenings at a ... Field. SPOT me™ is an educational campaign designed ... and risks of skin cancer, and encourages people to ...
Breaking Biology Technology:Sales Horizons Offers Mastering the Complex Sale - a Comprehensive, Online Sales Skills Training Course 2Sales Horizons Offers Mastering the Complex Sale - a Comprehensive, Online Sales Skills Training Course 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 3Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 2Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 3Chicago Bears Join the American Academy of Dermatology in Fight against Skin Cancer 4
... March 23, 2011 Advanced Cell Technology, Inc. ("ACT"; ... in the field of regenerative medicine, announced today that ... Company,s patent application to provide broad intellectual property protection ... retinal pigment epithelial (RPE) cells from human embryonic stem ...
... of survival tend to favor the strongest, but University ... world of self-healing materials, it is the somewhat frail ... Langmuir a new model laying out the ... particles that can regenerate after taking damage and are ...
... NEOG ) announced today that its net income ... 28, increased 27% from the previous year to $4,943,000 — ... $0.17 per share. Third quarter revenues increased ... company, compared to the prior year,s $33,833,000. Year to date, ...
Cached Biology Technology:ACT to Be Issued Broad Patent for Human ES Cell-derived RPE Cells in China 2ACT to Be Issued Broad Patent for Human ES Cell-derived RPE Cells in China 3Only the weak survive?: Pitt team adds more give for stronger self-healing materials 2Neogen Reports 27% Increase in Quarterly Net Income 2Neogen Reports 27% Increase in Quarterly Net Income 3Neogen Reports 27% Increase in Quarterly Net Income 4Neogen Reports 27% Increase in Quarterly Net Income 5Neogen Reports 27% Increase in Quarterly Net Income 6
poliovirus receptor-related 2 (herpesvirus entry mediator B), mRNA...
... consists of AmnioMAX-C100 Basal ... and AmnioMAX-C100 Supplement (Cat. ... complete with antibiotics and ... requires no further supplementation ...
Immunogen: Recombinant full length protein, corresponding to amino acids 1-435 of Human AP2M1. Storage: -20 C, Avoid Freeze/Thaw Cycles...
... Rabbit polyclonal to Parathyroid Hormone Receptor ... tested applications). Antigen: ... extracellular amino acids 99-116 of Human ... Entrez Gene ID: 5746 ...
Biology Products: