Navigation Links
Patterns of chromosome abnormality: The key to cancer?
Date:1/23/2012

omal layouts in a single cell and charted them according to commonalities. The researchers were not only able to confirm different chromosomal aberrations that appeared in specific cancer types, but also for the first time identified a broader effect of pairs of chromosomes being lost or gained together across different cancer types.

It was also the first time that researchers saw a connection among solid kidney, skeleton, and liver cancers. While it was known that these cancers all develop in the embryo, they were previously analyzed independently. The TAU researchers have now confirmed that they share chromosomal characteristics and aberrations, much like various forms of leukemia or lymphomas.

Aberrations a driving force for cancer

Under normal circumstances, even a small change to a person's chromosomal structure can be devastating. For example, Down's syndrome is caused by a single extra copy of Chromosome 21. "But in cancer, there are many cases of extra or missing chromosomes. Yet cancer cells thrive more effectively than other cells," Prof. Shamir says.

Prof. Shamir hopes that future investigation into these chromosomal aberrations will give researchers more clues into why something that is so detrimental to our healthy development is so beneficial to this disease. Cancer is the result of sequences of events, he says, each causing the genome to become more mutated, mixed, and duplicated. Tracking these changes could aid our understanding of the driving forces of cancer's progress.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Patterns of antibiotic-resistant bacteria found in Galapagos reptiles
2. Tool enables scientists to uncover patterns in vast data sets
3. Researchers link patterns seen in spider silk, melodies
4. Researcher finds key to ancient weather patterns in Floridas caves
5. Controlled disorder -- scientists find way to form random molecular patterns
6. Predators drive the evolution of poison dart frogs skin patterns
7. Contrasting patterns of malaria drug resistance found between humans and mosquitoes
8. Patterns of new DNA letter in brain suggest distinct function
9. West Nile virus transmission linked with land-use patterns and super-spreaders
10. Flight patterns reveal how mosquitoes find hosts to transmit deadly diseases
11. Scientists probe Indian Ocean for clues to worldwide weather patterns
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Patterns of chromosome abnormality: The key to cancer?
(Date:7/23/2014)... , , , , ... , , , , ... healthy lifespan. The idea, they argue, would be to target the... , , ... , , , , , ... , , , , , , , Medicine focuses almost entirely ...
(Date:7/23/2014)... Washington, DC -- The planet,s soil releases about 60 ... which is far more than that released by burning ... respiration. This enormous release of carbon is balanced by ... and other plant matter, as well as by the ... studies have documented that rising temperatures increase the rate ...
(Date:7/23/2014)... , July 23, 2014 BioCatch, ... detection, announced today it has been named in Gartner,s ... Market Guide replaces Gartner,s well-known Magic Quadrant for Web ... BioCatch as one of several vendors to deliver passive ... will become a standard feature of at least 30% ...
Breaking Biology News(10 mins):Strategy proposed for preventing diseases of aging 2Strategy proposed for preventing diseases of aging 3Strategy proposed for preventing diseases of aging 4Strategy proposed for preventing diseases of aging 5Climate change and the soil 2BioCatch Featured in Gartner's 2014 Online Fraud Detection Market Guide 2BioCatch Featured in Gartner's 2014 Online Fraud Detection Market Guide 3
... whole new interface between nanotechnology and neuroscience, scientists ... to detect, stimulate, and inhibit nerve signals along ... , Harvard chemist Charles M. Lieber and colleagues ... this week in the journal Science. , "We ...
... first time, researchers have developed a way to synthesize a ... it works. , Derived from a fungus discovered clinging to ... certain cancer cells into suicide while leaving healthy cells untouched. ... might have some tremendous potential as a prototype anticancer agent, ...
... Medical Research have discovered a mechanistic link between cellular ... proteins that lead to nerve cell injury and death ... , That link is Protein Disulphide Isomerase ... protein folding in times of cellular stress. Published ...
Cached Biology News:Nanowire arrays can detect signals along individual neurons 2New lab technique churns out fungus' potential cancer fighter 2Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's 2
(Date:7/23/2014)... the Vienna University of Technology and the Maria ... perfect semiconductor crystals into a silicon nanowire. With ... fast and multi-functional processing units can be accommodated ... research results will be published in the journal ... the cornerstone of future chip technology, but the ...
(Date:7/23/2014)... 23, 2014  AuraSense Therapeutics, the pioneer in developing ... regulatory and immunotherapeutic agents, announced today that ... Therapeutics, executive leadership team as chief financial ... to joining AuraSense Therapeutics, Mr. Snyder was ... of Cellular Dynamics International Inc., where he ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Last year, ... Systems , a leading global provider of data management ... with TrialMaster, a leading-edge system for electronic data capture ... of universal design and study execution tools added TrialMaster ... and much anticipated version of Transform for TrialMaster, is ...
(Date:7/23/2014)... 23 de julio de 2014 ADB ... Compañía) ha anunciado hoy una asociación con Austen ... (ABIA o el Instituto), para el propósito de ... de terapia de señal bioeléctrica (el E-QURE BST ... Instituto, que tiene una importante experiencia en cicatrización ...
Breaking Biology Technology:A crystal wedding in the nanocosmos 2AuraSense Therapeutics Appoints Biotechnology Veteran David S. Snyder as Chief Financial Officer 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 2ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 3ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 4ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 5ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 6
... CITY, Calif. , June 17 OncoMed Pharmaceuticals, Inc. ... global strategic alliance to discover, develop and commercialize novel anti-cancer stem ... a subset of tumor cells believed to play a significant role ... , , ...
... Institute have developed a new, ultra-simple method for ... of a meter thick. The process, which requires ... surface including silicon wafers, could have important implications ... assistant professor in the Department of Physics, Applied ...
... MD ... the functional relevance of a drug treatment on the heart following direct coronary flow ... ... MD Biosciences , a Preclinical Contract Research Organization (CRO), offers in vivo models for ...
Cached Biology Technology:OncoMed Pharmaceuticals and Bayer Schering Pharma Announce Strategic Alliance to Develop Anti-Cancer Stem Cell Therapeutics 2OncoMed Pharmaceuticals and Bayer Schering Pharma Announce Strategic Alliance to Develop Anti-Cancer Stem Cell Therapeutics 3OncoMed Pharmaceuticals and Bayer Schering Pharma Announce Strategic Alliance to Develop Anti-Cancer Stem Cell Therapeutics 4OncoMed Pharmaceuticals and Bayer Schering Pharma Announce Strategic Alliance to Develop Anti-Cancer Stem Cell Therapeutics 5Researchers develop ultra-simple method for creating nanoscale gold coatings 2MD Biosciences Offers Occlusion-induced Myocardial Infarct Model for Investigating the Cardio-protection of a Drug Treatment in the Event of Ischemia/reperfusion Injury 2
...
... ISOQUANT(R) Isoaspartate Detection Kit is intended for ... proteins and peptides, which can result from ... rearrangement of aspartic acid residues during storage ... depend on the monitoring of charge differences ...
...
...
Biology Products: