Navigation Links
Patterns of chromosome abnormality: The key to cancer?
Date:1/23/2012

omal layouts in a single cell and charted them according to commonalities. The researchers were not only able to confirm different chromosomal aberrations that appeared in specific cancer types, but also for the first time identified a broader effect of pairs of chromosomes being lost or gained together across different cancer types.

It was also the first time that researchers saw a connection among solid kidney, skeleton, and liver cancers. While it was known that these cancers all develop in the embryo, they were previously analyzed independently. The TAU researchers have now confirmed that they share chromosomal characteristics and aberrations, much like various forms of leukemia or lymphomas.

Aberrations a driving force for cancer

Under normal circumstances, even a small change to a person's chromosomal structure can be devastating. For example, Down's syndrome is caused by a single extra copy of Chromosome 21. "But in cancer, there are many cases of extra or missing chromosomes. Yet cancer cells thrive more effectively than other cells," Prof. Shamir says.

Prof. Shamir hopes that future investigation into these chromosomal aberrations will give researchers more clues into why something that is so detrimental to our healthy development is so beneficial to this disease. Cancer is the result of sequences of events, he says, each causing the genome to become more mutated, mixed, and duplicated. Tracking these changes could aid our understanding of the driving forces of cancer's progress.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Patterns of antibiotic-resistant bacteria found in Galapagos reptiles
2. Tool enables scientists to uncover patterns in vast data sets
3. Researchers link patterns seen in spider silk, melodies
4. Researcher finds key to ancient weather patterns in Floridas caves
5. Controlled disorder -- scientists find way to form random molecular patterns
6. Predators drive the evolution of poison dart frogs skin patterns
7. Contrasting patterns of malaria drug resistance found between humans and mosquitoes
8. Patterns of new DNA letter in brain suggest distinct function
9. West Nile virus transmission linked with land-use patterns and super-spreaders
10. Flight patterns reveal how mosquitoes find hosts to transmit deadly diseases
11. Scientists probe Indian Ocean for clues to worldwide weather patterns
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Patterns of chromosome abnormality: The key to cancer?
(Date:10/15/2014)... Geneticist Fred Alt will be awarded the 44th Rosenstiel ... University for his pioneering research exploring the mechanisms of ... and cancer cells. Alt is the second alumnus to ... the Nobel Prize in 2003. , Alt is the ... Genetics at Harvard Medical School and an investigator at ...
(Date:10/14/2014)... new study published in Cancer Research shows ... and colon cancers—can promote the development of skin cancers ... and survival of sun-damaged skin cells. , Previously considered ... proteins called sirtuins that help regulate genomic stability and ... SIRT6 helps repair DNA damage, which can lead to ...
(Date:10/14/2014)... how to produce enough food to feed the world ... Organization of the United Nations predicts that food production ... feed a growing global population, and plants are one ... Plants—grains, cereals, fruits, vegetables, and more—feed humans directly ... tap into our knowledge of how plants work to ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Building a bridge from basic botany to applied agriculture 2Building a bridge from basic botany to applied agriculture 3
... clear how salt, a scourge to agriculture, halts the growth ... the Carnegie Institution,s Jos Dinneny and Lina Duan, found that ... that an inner layer of tissue in the branching roots ... a stress hormone, which stops root growth. The study, published ...
... In a speech later today, Minister for Universities and ... research in Industrial Biotechnology and Bioenergy. The funding, from ... create networks and collaborative research between academia and industry ... UK and new ,green collar, jobs. The funding ...
... COLUMBIA, Mo. More than one-third of Americans are ... such as Type 2 diabetes and cardiovascular problems. In ... have suggested ways to improve the health outcomes of ... at the University of Missouri suggests certain exercises that ...
Cached Biology News:Breakthrough: How salt stops plant growth 2£35 million to support research for vital industrial sector 2Women must do more to reap same positive health outcomes as men, MU research suggests 2
(Date:10/22/2014)... (PRWEB) October 21, 2014 The ... the inorganic refrigerants market in Americas with analysis ... TOC of the Americas Inorganic Refrigerants Market report, ... provided. This also provides a glimpse of the ... is supported by various tables and figures. ...
(Date:10/22/2014)... NJ (PRWEB) October 22, 2014 ... and services – has been working with a team ... and New Haven Farms Community Farming Collaborative to provide ... ePRO solution. The study, which started in May, ... program that provides participants weekly exposure to and participation ...
(Date:10/22/2014)... October 22, 2014 According to ... by Service Type (Consulting, Integration, Deployment & Support), ... Deployment Model (Public, Private, Others (Hybrid & Community)) ... defines and segments the Cloud Professional Services Market ... forecasting of revenues. It also identifies the drivers ...
(Date:10/22/2014)... DUBLIN , Oct. 22, 2014 ... "Organic Electronics Market by Material, by Application, Geography ... report to their offering. Organic electronics, ... a branch of material science which deals with small ... as organic because small molecules and polymers are carbon ...
Breaking Biology Technology:The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 2The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 3myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 2myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 2Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 3
... InterMune, Inc.,(Nasdaq: ITMN ) announced today that it ... 6, 2008 at 4:00 p.m. Eastern time.,A live conference ... 4:30 p.m.,Eastern time that same day., To access ... ID# 71184785. To access the,webcast, please log on to ...
... in U.S. Phase II Study,of Nitazoxanide in Treatment-Naive ... Fla., Oct. 28 Romark Laboratories, a privately,held ... nitazoxanide at the upcoming 59th Annual Meeting of ... (AASLD), also known as The,Liver Meeting(R), and the ...
... Affitech AS, the human,therapeutic antibody company, today ... to the innovative diabody technology originally owned ... vaccine company. Also known as,bi-specific single chain ... attributes make them attractive,candidates for a variety ...
Cached Biology Technology:InterMune to Release Third Quarter 2008 Financial Results on November 6 2Romark Laboratories Announces Presentation of New Nitazoxanide Data at 59th Annual AASLD Meeting and 50th Anniversary IASL Meeting in San Francisco 2Affitech Acquires Pharmexa's Diabody Technology 2
...
Peptide-affinity Purified Polyclonal Antibody to MAML1 / Mastermind Peptide with sequence VLPTCPMAEFALPR, from N Terminus of the protein sequence according to NP_055572....
Mouse monoclonal [5H9] to RAD52 ( Abpromise for all tested applications). entrezGeneID: 5893 SwissProtID: P43351...
... the family of calcium binding proteins such as ... of an alpha and beta chain whereas S100B ... protein is also expressed in the antigen presenting ... and interdigitating reticulum cells in the paracortex of ...
Biology Products: