Navigation Links
PMH researchers create an organic nanoparticle that uses sound and heat to find and treat tumors
Date:3/20/2011

A team of scientists from Princess Margaret Hospital have created an organic nanoparticle that is completely non-toxic, biodegradable and nimble in the way it uses light and heat to treat cancer and deliver drugs. (A nanoparticle is a minute molecule with novel properties).

The findings, published online today in Nature Materials (DOI: 10.1038/NMAT2986) are significant because unlike other nanoparticles, the new nanoparticle has a unique and versatile structure that could potentially change the way tumors are treated, says principal investigator Dr. Gang Zheng, Senior Scientist, Ontario Cancer Institute (OCI), Princess Margaret Hospital at University Health Network.

Dr. Zheng says: "In the lab, we combined two naturally occurring molecules (chlorophyll and lipid) to create a unique nanoparticle that shows promise for numerous diverse light-based (biophotonic) applications. The structure of the nanoparticle, which is like a miniature and colorful water balloon, means it can also be filled with drugs to treat the tumor it is targeting."

It works this way, explains first author Jonathan Lovell, a doctoral student at OCI: "Photothermal therapy uses light and heat to destroy tumors. With the nanoparticle's ability to absorb so much light and accumulate in tumors, a laser can rapidly heat the tumor to a temperature of 60 degrees and destroy it. The nanoparticle can also be used for photoacoustic imaging, which combines light and sound to produce a very high-resolution image that can be used to find and target tumors." He adds that once the nanoparticle hits its tumor target, it becomes fluorescent to signal "mission accomplished".

"There are many nanoparticles out there, but this one is the complete package, a kind of one-stop shopping for various types of cancer imaging and treatment options that can now be mixed and matched in ways previously unimaginable. The unprecedented safety of this nanoparticle in the body is t
'/>"/>

Contact: Sommer Ellis
sommer.ellis@uhn.on.ca
416-340-4011
University Health Network
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... A new study reports that an expansion of marine ... perform key ecological functions. According to investigators from ... at protecting fish have focused on saving the largest ... species that provide key and difficult-to-replace ecological functions. ... are performed by fish species that also are food ...
(Date:8/28/2014)... Access to Research Careers) Program has announced the travel ... from October 18 22, 2014 in San Diego, ... entry of students, post doctorates and scientists from underrepresented ... and to encourage the participation of young scientists at ... MARC conferred 16 awards totaling $29,600., The FASEB MARC ...
(Date:8/28/2014)... FASEB MARC (Maximizing Access to Research Careers) Program ... Genetics Society of America,s 27th Annual Mouse Molecular ... 2014 in Pacific Grove, California. These awards ... post doctorates and scientists from underrepresented groups into ... to encourage the participation of young scientists at ...
Breaking Biology News(10 mins):Study finds marine protected areas inadequate for protecting fish and ocean ecology 2
... fungi, often found in composts that self-ignite without flame or ... of Myceliophthora thermophila and Thielavia terrestris ... The findings, published in Nature Biotechnology , may ... chemicals and other industrial materials. "Organisms that thrive ...
... release is available in German . They ... model of evolutionary success: viruses. Viruses are extremely adaptable but they ... into suitable host cells. In the case of some viruses, the ... has been known for almost 50 years. We know, for instance, ...
... Spanish . , The cayenne tick has ... in horses in a 2009 Texas outbreak, according to U.S. ... been considered free from the disease since 1978, but sporadic ... Kleberg County, Texas, a mare was presented for veterinary care ...
Cached Biology News:From compost to sustainable fuels: Heat-loving fungi sequenced 2Manipulated gatekeeper: How viruses find their way into the cell nucleus 2Tick responsible for equine piroplasmosis outbreak identified 2
(Date:8/28/2014)... Vt. (PRWEB) August 28, 2014 ... testing around the world is available from Strategic ... diagnostics companies. “ Industrial Microbiology Market Review, Fourth ... Industrial Market ” (IMMR—4) tracks and compares microbiology ... in North America, Europe and Asia, and forecasts ...
(Date:8/28/2014)... PrimeSource Building Products, Inc., a leading ... to support their communication needs with the ... conferencing platform GlobalMeet powered by SoundConnect. The solution ... SoundConnect delivers award winning “results driven” business class ... be utilizing GlobalMeet powered by SoundConnect ...
(Date:8/28/2014)... Whitehouse Laboratories is excited to announce ... PTI Inspection Systems that will enable it ... art leak testing method development and validation programs using ... As part of this agreement, Whitehouse Labs has taken ... Instrument developed and manufactured by PTI. The HVLD ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 Green & ... in Series B funding and secured Otter Capital as ... capital will accelerate commercialization of GGI’s Agriplier™ technology, building ... types. , “Since our first meeting, we have ... the biological product space,” said Alan Sobba, President and ...
Breaking Biology Technology:2 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3PrimeSource Chooses SoundConnect as Collaboration Provider 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 2Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 3
... Stem Cell Institute,(RSCI) today announced two additions to ... cell research proficiency in the process.,Don Margolis, RSCI ... two,things in common: pioneering stem cell research and ... incurable. Today we add two,Massachusetts researchers, David Matzilevich, ...
... - Company Appoints Charles Rowland to Chief Financial ... ViroPharma Incorporated,(Nasdaq: VPHM ) today announced that ... strengthened its leadership in human resources,clinical development and ... vice president and chief financial officer; Thomas Macnamara ...
... Force ... ANX-514, - Company to Present Updated Corporate Outlook at ... Pharmaceuticals,Inc. (Amex: ANX ) announced today that it has ... towards the,Company,s near term goals. ADVENTRX will focus its resources ...
Cached Biology Technology:RSCI Announces Two Additions to Its Science Advisory Board, Calling for More Stem Cell Research on Diabetes 2ViroPharma Enhances Leadership to Support Global Growth and Expanding Business 2ViroPharma Enhances Leadership to Support Global Growth and Expanding Business 3ViroPharma Enhances Leadership to Support Global Growth and Expanding Business 4ViroPharma Enhances Leadership to Support Global Growth and Expanding Business 5ADVENTRX Announces Restructuring and Cost Reduction Initiatives 2ADVENTRX Announces Restructuring and Cost Reduction Initiatives 3ADVENTRX Announces Restructuring and Cost Reduction Initiatives 4ADVENTRX Announces Restructuring and Cost Reduction Initiatives 5ADVENTRX Announces Restructuring and Cost Reduction Initiatives 6
The BD CBA Human Apoptosis Kit can be used to quantitatively measure,cleaved PARP, Bcl-2, and active Caspase-3 protein levels in a single sample. The,Kit performance has been optimized for analysis o...
... Activation of ICE-family proteases/caspases initiates apoptosis in ... Apoptosis Detection Kit provides a simple and ... by flow cytometry in intact cells. ... two aspartate residues linked to rhodamine 110 ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
... direct antibiotic-based selection system for recombinant identification. ... eliminating the need for costly color screening. ... to 100% accuracy in recombinant selection. pLivSelect ... colony picking. This cloning kit can be ...
Biology Products: