Navigation Links
PMH researchers create an organic nanoparticle that uses sound and heat to find and treat tumors
Date:3/20/2011

A team of scientists from Princess Margaret Hospital have created an organic nanoparticle that is completely non-toxic, biodegradable and nimble in the way it uses light and heat to treat cancer and deliver drugs. (A nanoparticle is a minute molecule with novel properties).

The findings, published online today in Nature Materials (DOI: 10.1038/NMAT2986) are significant because unlike other nanoparticles, the new nanoparticle has a unique and versatile structure that could potentially change the way tumors are treated, says principal investigator Dr. Gang Zheng, Senior Scientist, Ontario Cancer Institute (OCI), Princess Margaret Hospital at University Health Network.

Dr. Zheng says: "In the lab, we combined two naturally occurring molecules (chlorophyll and lipid) to create a unique nanoparticle that shows promise for numerous diverse light-based (biophotonic) applications. The structure of the nanoparticle, which is like a miniature and colorful water balloon, means it can also be filled with drugs to treat the tumor it is targeting."

It works this way, explains first author Jonathan Lovell, a doctoral student at OCI: "Photothermal therapy uses light and heat to destroy tumors. With the nanoparticle's ability to absorb so much light and accumulate in tumors, a laser can rapidly heat the tumor to a temperature of 60 degrees and destroy it. The nanoparticle can also be used for photoacoustic imaging, which combines light and sound to produce a very high-resolution image that can be used to find and target tumors." He adds that once the nanoparticle hits its tumor target, it becomes fluorescent to signal "mission accomplished".

"There are many nanoparticles out there, but this one is the complete package, a kind of one-stop shopping for various types of cancer imaging and treatment options that can now be mixed and matched in ways previously unimaginable. The unprecedented safety of this nanoparticle in the body is t
'/>"/>

Contact: Sommer Ellis
sommer.ellis@uhn.on.ca
416-340-4011
University Health Network
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)...  That blood pressure plays a role in human health has ... term for high blood pressure – was first described as ... that,s used in measuring blood pressure was invented in 1896. ... hypertension, its triggers and its effects. In fact, recent findings ...
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into your ... the answer to your secret question. What,s your dog,s birthday? Who ... Labs , a digital infrastructure security company, launches the ... comes with usernames, passwords and PINs – 1U TM ...
(Date:12/10/2014)... 2014  Wake Forest Baptist Medical Center today announced plans for ... Funding for this $50 million capital project is part of ... summer. The medical education building will be ... complex, adjacent to 525@vine in Wake Forest Innovation Quarter. Construction ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4
... protein associated with Alzheimer's disease in the brain of ... between neuronal death and proteins previously associated with cancer. ... Feany, and colleagues from Brigham and Women's Hospital, Harvard ... the brain generally do not divide. It is therefore ...
... that tend and harvest gardens of fungus have ... their crops: antibiotic-producing bacteria that the insects harbor ... journal Science, an international team led by University ... and ancient nature of this mutualistic relationship. ...
... pollution is a serious and growing environmental problem, especially ... Georgia had, several years ago, used genetic techniques to ... sites. , There was a problem, however. The arsenic ... the plant, making it difficult to harvest for safe ...
Cached Biology News:Study reveals classic symbiotic relationship between ants, bacteria 2Study reveals classic symbiotic relationship between ants, bacteria 3Researchers discover way to transport environmental arsenic to plant leaves in new clean-up strategy 2
(Date:1/22/2015)...  Transwestern | RBJ today announces the firm brokered a long-term ... a leading biopharmaceutical company, at Two Ledgemont Center in ... Richards , president, and Brian Cohen , senior vice ... building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... San Diego, California (PRWEB) January 22, 2015 ... R Promotional Offer to their comprehensive portfolio of ... Offer allows customers to purchase a Centrifuge 5424/5424 R ... Pipette Bundle of either Eppendorf Research plus or Eppendorf ...
(Date:1/22/2015)... 22, 2015 Diagenode, Inc., a ... the Bioruptor® and complete solutions for epigenetics research, ... immunoprecipitation, alleviating the need for manual processing. The ... for ChIP of histones or transcription factors and ...
(Date:1/22/2015)... N.J. , Jan. 22, 2015  Derma Sciences, ... regeneration company focused on advanced wound care, announces ... placental tissues, have been added to the Premier, ... increases the opportunity for the AMNIOEXCEL® and AMNIOMATRIX® ...
Breaking Biology Technology:Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5
... - Oncolytics Biotech Inc. (TSX:ONC, NASDAQ: ONCY ) ... for the year ended December 31, 2008. , "In ... said Dr. Brad Thompson, President and CEO of Oncolytics. ... by interim results reported in our US and UK ...
... Venture: QPTEDMONTON, March 4 /PRNewswire-FirstCall/ - Quest PharmaTech ... pharmaceutical company developing and commercializing products for the ... results from a study designed to investigate the ... (PDT) used in combination with immunotherapeutic agents in ...
... N.C., March 4 Micell Technologies announced today ... Micell Rapid Absorption Polymer DES System" during the ... on March 5, 2009. MiStent(TM), a Drug-Eluting Stent ... coating that delivers the potential benefits of the ...
Cached Biology Technology:Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 2Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 3Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 4Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 5Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 6Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 7Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 8Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008 9Quest PharmaTech Announces Results Showing its Photosensitizer, SL052, is an Effective Immuno-Stimulant when combined with Immunotherapy for the Removal of Solid Tumors 2Quest PharmaTech Announces Results Showing its Photosensitizer, SL052, is an Effective Immuno-Stimulant when combined with Immunotherapy for the Removal of Solid Tumors 3Micell Technologies' Rapid Absorption Polymer DES System to be Presented at CRT 2009 2
Polio component type I...
Procollagen type I C-terminal propeptide (human, PICP)...
Choriongonadotropin (human, hCG)...
... LC Sciences provides a comprehensive microarray ... regulatory/functional RNA embedded within non-coding RNAs ... and proprietary probe design, which enables ... of small RNAs (1). This comprehensive ...
Biology Products: