Navigation Links
Ovarian transplantation: New technique gives greatly improved results in this delicate operation
Date:6/29/2009

Amsterdam, The Netherlands: Ultra-fast freezing of ovarian tissue from women who have lost their fertility as a result of cancer treatment can lead to it being used in transplants with the same success rate as fresh tissue, a researcher told the 25th annual conference of the European Society of Human Reproduction and Embryology today (Monday 29 June). Dr. Sherman Silber, Director of the St. Louis Infertility Centre, St. Louis, Missouri, USA, said that freezing tissue by the vitrification method, which avoids ice formation, meant that oocyte (egg) viability was almost identical with that seen in fresh oocytes.

Dr. Silber and colleagues used standard viability testing with fluorescent microscopy to determine the loss or preservation of oocytes in fresh and frozen ovarian tissue of 15 young women undergoing cancer treatment. They also followed up nine homozygotic twin patients after fresh ovary transplantation for the duration of ovarian function and pregnancy outcome, and tested spare tissue that had also been frozen from their ovaries at the time of transplant. Tissue was preserved either by rapid cooling vitrification or by classical slow freezing methods.

"We found that 91.9% of the fresh oocytes were viable compared with 88.9% of those vitrified. However, slow freezing resulted in a 56% loss of viability", said Dr. Silber.

Transplantation of the tissue resulted in a duration of ovarian function of more than four years in five of the seven cases followed up for that long, and all patients regained a normal ovarian cycle within four to five months after the transplant. There was no difference in terms of pregnancy or ovulatory menstrual cycling between fresh and frozen grafts. The scientists used the cortical grafting technique, where very thin slices of tissue are transplanted. This technique is much easier to perform than the delicate microvascular technique, which they described last year in an effort to prevent egg loss and to le
'/>"/>

Contact: MaryRice
mary@mrccommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Genetic testing for breast or ovarian cancer risk may be greatly underutilized
2. Promising new treatment option for women with recurrent ovarian cancer
3. TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer
4. Oocyte-specific gene mutations cause premature ovarian failure
5. Ovarian cancer stem cells identified, characterized
6. Mutation of the COX2 gene can double or treble a womans risk of ovarian cancer
7. Colon cancer screening technique shows continued promise in new study
8. Beating heart machine expedites research and development of new surgical tools, techniques
9. New genomic technique uncovers coral transcriptome
10. Lyncean Technologies Inc. receives $1.2 M from NCRR to develop new imaging technique
11. Indigenous peoples at world summit to share climate change observations, coping techniques
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... "electronic-nose" for sniffing the highly infectious bacteria C. ... has been developed by a team at the University ... team has demonstrated that it is possible to identify ... would lead to rapid diagnosis of the condition., What ... possible to identify different strains of the disease simply ...
(Date:8/31/2014)... Over the past several decades, malaria diagnosis has changed very ... technician smears the blood across a glass slide, stains it ... the Plasmodium parasite, which causes the disease. This approach gives ... blood an important measure of disease severity but ... , A research team from the Singapore-MIT Alliance for Research ...
(Date:8/29/2014)... University of Texas Medical Branch at Galveston has gone on ... completely protect monkeys against a lethal dose of Ebola virus ... the disease is severe. , Thomas Geisbert, professor of microbiology ... discussing advances in Ebola treatment research. The filoviruses known as ... of pathogens, with fatality rates of up to 90 percent. ...
Breaking Biology News(10 mins):Scientists develop 'electronic nose' for rapid detection of C. diff infection 2A new way to diagnose malaria 2A new way to diagnose malaria 3Leading Ebola researcher at UTMB says there's an effective treatment for Ebola 2
... first experimental evidence that birds can be deceived by camouflage ... today in Nature [3 March 2005]. , The idea that ... rapidly adopted by many armies as long ago as the ... colouration' has long been used to explain how insects such ...
... that radio-tracking could be affecting the animals they ... in the British Ecological Society's Journal of Applied ... with a "dramatic shift" in the sex ratio ... assumption that radio-tracking does not fundamentally affect the ...
... Blackburn is responsible for collecting and storing thousands of ... -- to make sure there's enough genetic material to ... deals with important livestock such as Holstein cattle and ... who is the coordinator of the animal section at ...
Cached Biology News:Radio-tracking associated with 'dramatic shift' in water vole sex ratio 2Making Sure Sacred Sheep Don't Become Extinct 2
(Date:8/31/2014)... Available spectra is similar for ... and cultivation of a wide range of plants. ... with proven patented and pending wide spectrum technology. ... in critical applications in contrast to growth spectra ... customers have a large variety of differently sized ...
(Date:8/29/2014)... Electronic circuits are based on electrons, but one of ... photonic circuits, i.e. circuits based on light (photons) instead ... to create a stream of single photons and control ... sorts of attempts to achieve this control, but now ... creating a steady stream of photons emitted one at ...
(Date:8/29/2014)... Hills, NY (PRWEB) August 29, 2014 ... Burnt Hills Veterinary Hospital are seeking candidates to participate ... dogs with osteoarthritis. The ultimate goal of this ... donor stem cells into one or two arthritically affected ... treated joints. , Candidates for the current investigational ...
(Date:8/28/2014)... USA (PRWEB) August 28, 2014 SPIE ... of Physics and Optical Science and Director of the ... of North Carolina at Charlotte, and co-founder and Chairman ... to serve as the 2015 Vice President of SPIE, ... 2014 President Philip Stahl announced recent election results at ...
Breaking Biology Technology:Breakthrough in light sources for new quantum technology 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... Previous Quarter, NEW YORK, May 15 ... biosensor and microprocessor technologies for,use in portable monitoring ... ended March 31, 2008., Gross revenues for ... quarter 2007 gross revenues. The increase in revenues ...
... YORK, May 15 American Oriental,Bioengineering, Inc. (NYSE: ... health through the development, manufacture and commercialization,of a ... ("OTC") products in,China, today released the following statement ... with the many victims of China,s earthquake and ...
... 15 /Xinhua-PRNewswire-FirstCall/ -- Huifeng Bio-,Pharmaceutical Technology, Inc. ... producer of plant extracts and pharmaceutical raw ... production, today,announced that there was no damage ... the Sichuan Earthquake., Immediately following the ...
Cached Biology Technology:SPO Medical Reports First Quarter 2008 Results 2SPO Medical Reports First Quarter 2008 Results 3American Oriental Bioengineering Comments on Earthquake 2Huifeng Bio-Pharmaceutical (HFGB) Announces No Earthquake Related Damage to Facilities 2
BD Primaria 35 mm Cell Culture Dish with Easy-Grip design, surface-modified polystyrene for enhanced cell culture. (20/sp, 200/ca) Packaging: 20 / sleeve, 500 / case ...
... is a software package that provides ... for custom buffer creation, set-up of ... crystallization trials. The software helps crystallographers ... automated protein crystallography: ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Mouse monoclonal [H4B4] to LAMP2 - Lysosome Marker (Phycoerythrin) ( Abpromise for all tested applications). entrezGeneID: 3920 SwissProtID: P13473...
Biology Products: