Navigation Links
Oregon researchers say supplement cuts muscle loss in knee replacements
Date:10/25/2013

EUGENE, Ore. -- (Oct. 25, 2013) -- Twenty grams of essential amino acids taken twice daily for a week before and for two weeks after knee-replacement surgeries helped 16 patients, mean age 69, recover faster and with much less muscle atrophy than a control group ingesting a placebo.

The approach -- detailed in a paper now online ahead of print in the Nov. 13 issue of the Journal of Clinical Investigation -- could spell relief and speed recovery for a growing population of aging adults who face total knee-replacements because of loss of mobility and pain problems. An estimated 3.48 million Americans are projected to need the surgery, known as total knee arthroplasty (TKA), by 2030.

The findings are part of an ongoing collaboration led by Hans C. Dreyer, a professor of human physiology at the University of Oregon, with the Eugene-based Slocum Research & Education Foundation and the Oregon Research Institute.

Atrophy in the quadriceps, a group of four muscles on the front of the thigh, has been a long-running problem following knee-replacement surgeries, Dreyer said.

In the study, 12 members of a control group receiving 40 grams a day of a non-essential amino acid supplement, a placebo, averaged an 18.4 loss in quadriceps muscle mass in their operated leg six weeks after surgery; those getting the supplement of eight essential amino acids (EEA) averaged a 6.2 percent loss. Eighty percent of atrophy occurred in the first two weeks after surgery. Atrophy in non-operative legs was about 50 percent of that in the operative leg in both groups. Muscle mass changes were seen with magnetic resonance imaging done at two and six weeks after surgery.

"We've learned that the essential amino acids were able to mitigate the amount of muscle loss," Dreyer said. "The functional measures that we looked at -- getting up out of a chair, going up a flight of stairs and going back down the stairs -- were all back to baseline in the t
'/>"/>

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Oregon Biodiversity Information Center wins 2013 Natureserve Network Collaboration Award
2. Ken Bierly of the Oregon Watershed Enhancement Board to receive ESA Regional Policy Award
3. BUSM researchers identify molecule that could aid lung cancer detection, treatment
4. Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
5. Researchers show how plants tell the time
6. Berkeley Lab researchers get a detailed look at a DNA repair protein in action
7. Researchers capture images of open channel that moves proteins across cell membranes
8. UAlberta medical researchers discover potential new treatment for colitis
9. Older siblings cells can be passed from female dogs to their puppies in the womb, MU researchers find
10. Nitrogen fertilizer remains in soils and leaks towards groundwater for decades, researchers find
11. Researchers discover innate virus-killing power in mammals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oregon researchers say supplement cuts muscle loss in knee replacements
(Date:10/29/2014)... of the Barcode of Life Data Systems ... Biodiversity Data Journal (BDJ) used specimen records ... into a human-readable text developed in manuscript within the ... to study the species distributions of ten Nearctic species ... is originally designed to support the generation and application ...
(Date:10/29/2014)... Ghrelin is a hormone released by the stomach and ... viewed as a psychoactive substance that primarily affects brain ... , This knowledge, combined with findings from animal ... the potential to stimulate alcohol craving. , Dr. Lorenzo ... found that, as they had anticipated, alcohol craving was ...
(Date:10/28/2014)... is that the drugs used to treat it ... from patient to patient. However, a new "tumor-in-a-dish" ... rapidly assessing how effective specific anti-cancer cocktails will ... , A team of biomedical engineers at Vanderbilt ... developed the technique, which uses fluorescence imaging to ...
Breaking Biology News(10 mins):Go straight and publish: From Barcode of Life Data Systems to scholarly publishing systems 2Ghrelin stimulates an appetite for drinking alcohol 2Improving breast cancer chemo by testing patient's tumors in a dish 2Improving breast cancer chemo by testing patient's tumors in a dish 3
... been thought to be important only to translate a gene's ... evidence shows that tiny bits of RNA not used to ... in the development of cancers. , "Scientists have known for ... as microRNAs, is only supposed to happen at certain times ...
... producing embryonic-like cells from umbilical cord blood may substantially ... injuries and disabilities. The discovery made during a project ... Branch and the Synthecon Corporation in the United States ... reliable source of human stem cells for the first ...
... who take soy or herbal supplements, such as black ... care, says a Cornell University expert affiliated with the ... at Cornell, the land-grant institution of New York state. ... herbal medicines can increase or decrease breast cancer risk, ...
Cached Biology News:Once given 'no respect,' cells' tiny RNAS take driver's seat 2Once given 'no respect,' cells' tiny RNAS take driver's seat 3Researchers propose measures to curb lion attacks in Tanzania 2Women cautioned against using herbal supplements 2Women cautioned against using herbal supplements 3
(Date:10/27/2014)... 27, 2014 New Q4-2014 incentives ... , an industry leading unified communication and collaboration ... agents to deliver cloud-based audio and web/video conferencing ... , With SoundConnect’s Q4 incentive partners ... and/or web conferencing licenses sold, now through December ...
(Date:10/27/2014)... Mass. , Oct. 27, 2014 ... "Company"), a worldwide leader in the development and ... the life sciences research market, today announced that ... presented a novel, accurate, highly reproducible, and robust ... – routine high-throughput protein analysis on small needle ...
(Date:10/26/2014)... The report "Data Center Networking Market ... WAN Optimization Appliances]: Global Advancements, Worldwide Forecasts & ... networking market into various segments with an in-depth ... identifies the factors driving this market, various restraints ... the future roadmaps. , Browse 106 market data ...
(Date:10/25/2014)... (PRWEB) October 23, 2014 ... specialty pharmaceutical company devoted to bringing new products ... in 2015. , ViaDerma has developed an innovative, ... for rapid mass transfer of pharmaceutical active ingredients ... to provide immediate localized therapy. The transdermal delivery ...
Breaking Biology Technology:SoundConnect Unveils Q4 Partner Incentives 2Breakthrough Method to Permit Quantification of Thousands of Proteins in Needle Biopsy Samples in 12 hours Presented at Major International Scientific Meeting; Method Enabled by Pressure BioSciences' PCT Sample Preparation Platform 2Breakthrough Method to Permit Quantification of Thousands of Proteins in Needle Biopsy Samples in 12 hours Presented at Major International Scientific Meeting; Method Enabled by Pressure BioSciences' PCT Sample Preparation Platform 3Breakthrough Method to Permit Quantification of Thousands of Proteins in Needle Biopsy Samples in 12 hours Presented at Major International Scientific Meeting; Method Enabled by Pressure BioSciences' PCT Sample Preparation Platform 4Breakthrough Method to Permit Quantification of Thousands of Proteins in Needle Biopsy Samples in 12 hours Presented at Major International Scientific Meeting; Method Enabled by Pressure BioSciences' PCT Sample Preparation Platform 5Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 2Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 3Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 4ViaDerma, Inc. Announces Plans to Pursue Out-Licensing Partnerships in 2015 2ViaDerma, Inc. Announces Plans to Pursue Out-Licensing Partnerships in 2015 3
... - Ohio State University's new "living laboratory" of ... system developed by Madison-based Sonic Foundry, Inc. ... instructors' presentations, the company announced Monday. , ,The ... provide Ohio State with data for making informed ...
... its Show on the road. Convinced that American companies are ... eight-day, 18-city bus tour called Show Us the Jobs ... anti-offshoring Web sites were among the 51 people who toured ... by the Bush administration to promote a growing economy. , ...
... The Sachs-Bloomberg Global Biotech Forum for Investing & ... its forum in Boston, April 1-2. The conference is designed ... companies. , ,The chance to raise venture capital on the ... operating officer at ConjuGon. "I think we're unlike a lot ...
Cached Biology Technology:Ohio State's educational tech lab to use Sonic Foundry system 2Theres a surprising, and positive, side to the offshore jobs debate 2Theres a surprising, and positive, side to the offshore jobs debate 3
... catalyzes the formation of a phosphodiester bonds ... nicked duplex DNA molecules or between oligonucleotides ... strand at 45 - 65?. Tfi DNA ... higher temperatures than conventional DNA ligases, Thus, ...
RABBIT ANTI RHEB (IN) Immunogen: A 15 amino acid peptide located in the central region of human Rheb....
Rabbit polyclonal antibody to Neuromedin U Receptor 1 (GPR66)...
... causing shortages in your laboratory or fellow researchers ... distractions, problems and delays. • ... endeavour! Bring us your idea and let us ... work under ISO 9001 quality assurance in design, ...
Biology Products: