Navigation Links
Oregon researchers say supplement cuts muscle loss in knee replacements
Date:10/25/2013

EUGENE, Ore. -- (Oct. 25, 2013) -- Twenty grams of essential amino acids taken twice daily for a week before and for two weeks after knee-replacement surgeries helped 16 patients, mean age 69, recover faster and with much less muscle atrophy than a control group ingesting a placebo.

The approach -- detailed in a paper now online ahead of print in the Nov. 13 issue of the Journal of Clinical Investigation -- could spell relief and speed recovery for a growing population of aging adults who face total knee-replacements because of loss of mobility and pain problems. An estimated 3.48 million Americans are projected to need the surgery, known as total knee arthroplasty (TKA), by 2030.

The findings are part of an ongoing collaboration led by Hans C. Dreyer, a professor of human physiology at the University of Oregon, with the Eugene-based Slocum Research & Education Foundation and the Oregon Research Institute.

Atrophy in the quadriceps, a group of four muscles on the front of the thigh, has been a long-running problem following knee-replacement surgeries, Dreyer said.

In the study, 12 members of a control group receiving 40 grams a day of a non-essential amino acid supplement, a placebo, averaged an 18.4 loss in quadriceps muscle mass in their operated leg six weeks after surgery; those getting the supplement of eight essential amino acids (EEA) averaged a 6.2 percent loss. Eighty percent of atrophy occurred in the first two weeks after surgery. Atrophy in non-operative legs was about 50 percent of that in the operative leg in both groups. Muscle mass changes were seen with magnetic resonance imaging done at two and six weeks after surgery.

"We've learned that the essential amino acids were able to mitigate the amount of muscle loss," Dreyer said. "The functional measures that we looked at -- getting up out of a chair, going up a flight of stairs and going back down the stairs -- were all back to baseline in the t
'/>"/>

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Oregon Biodiversity Information Center wins 2013 Natureserve Network Collaboration Award
2. Ken Bierly of the Oregon Watershed Enhancement Board to receive ESA Regional Policy Award
3. BUSM researchers identify molecule that could aid lung cancer detection, treatment
4. Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
5. Researchers show how plants tell the time
6. Berkeley Lab researchers get a detailed look at a DNA repair protein in action
7. Researchers capture images of open channel that moves proteins across cell membranes
8. UAlberta medical researchers discover potential new treatment for colitis
9. Older siblings cells can be passed from female dogs to their puppies in the womb, MU researchers find
10. Nitrogen fertilizer remains in soils and leaks towards groundwater for decades, researchers find
11. Researchers discover innate virus-killing power in mammals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oregon researchers say supplement cuts muscle loss in knee replacements
(Date:8/28/2014)... roads will be built worldwide by 2050. Many of ... they bring an influx of destructive loggers, hunters and ... created a ,global roadmap, for prioritising road building across ... of development and environmental protection. , The map has ... importance of ecosystems and a ,road-benefits, layer that estimates ...
(Date:8/28/2014)... homes could pose a significant health risk to people with ... Journal of Allergy and Clinical Immunology . , By critically ... the research has found that the presence of several types ... as well as increasing the likelihood of developing the condition. ... the University of Exeter Medical School and is the first ...
(Date:8/28/2014)... exports from Washington, Oregon, northern California, and Alaska totaled ... quarter of 2014, an increase of more than 10 ... U.S. Forest Service,s Pacific Northwest Research Station reported today. ... by 4 percent to 247 million board feet. , ... more than 5 percent to $390 million in the ...
Breaking Biology News(10 mins):Study shows where on the planet new roads should and should not go 2Study shows where on the planet new roads should and should not go 3Indoor mold poses health risk to asthma sufferers 2West coast log exports up, lumber exports down in second quarter of 2014 2
... the Science of Food and Agriculture shows that konjac ... strains of E. coli and Salmonella bacteria. The study ... Research Centre, the Netherlands, shows that these foodstuffs act as ... themselves to the fibrous foods instead of the gut cells ...
... an ice-free region of Antarctica have discovered the last ... insects--on the interior of the southernmost continent before temperatures ... An abrupt and dramatic climate cooling of 8 degrees ... roughly 14 million years ago, forced the extinction of ...
... (August 5, 2008) A study published online today in ... two eggs for breakfast, as part of a reduced-calorie diet, ... than those who eat a bagel breakfast of equal calories. ... Journal of the American College of Nutrition , which ...
Cached Biology News:Antarctic fossils paint a picture of a much warmer continent 2Antarctic fossils paint a picture of a much warmer continent 3Antarctic fossils paint a picture of a much warmer continent 4Antarctic fossils paint a picture of a much warmer continent 5Adults who eat eggs for breakfast lose 65 percent more weight 2Adults who eat eggs for breakfast lose 65 percent more weight 3
(Date:8/28/2014)... Scientists, researchers, and technologists will converge ... Damage 2014 symposium. Marking its 46th year, the ... run 14-17 September. The event is sponsored by ... , The premier conference for basic and applied issues ... materials will engage researchers and engineers from numerous industries ...
(Date:8/28/2014)... August 28, 2014 Supplementing their ... a promotion for Eppendorf Safe Lock Centrifuge ... purchase the highest quality tubes at an affordable ... for customers doing chemical, medical, pharmaceutical, and life ... are not regularly able to afford Eppendorf products. ...
(Date:8/27/2014)... 27, 2014 Rhythm, a biopharmaceutical company developing ... that result in metabolic disorders, announced today that it ... the U.S. Securities and Exchange Commission (SEC) relating to ... common stock. The number of shares to be offered ... yet been determined. Citigroup and Cowen and ...
(Date:8/27/2014)... of nature,s mysteries is how plants survive impact ... the sun,s rays, while using this energy for ... in the plant,s blades quickly dissipate the energy ... quakes. Researchers at DTU Physics have now managed ... algae and bacteria contain light-absorbing proteins which play ...
Breaking Biology Technology:Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3Rhythm Files Registration Statement for Proposed Initial Public Offering 2DTU researchers film protein quake for the first time 2
... Inc. (Nasdaq:,CEPH) announced today that the presentation slides that ... Conference are now available on the,"Investor Information" section of ... 8, 2008, Frank Baldino, Jr.,Ph.D., Chairman and CEO, will ... 2:00 p.m. Pacific Time (5 p.m. Eastern Time)., ...
... Record of Investment Success -, GAITHERSBURG, Md., ... unit of AstraZeneca plc (LSE: AZN.L, NYSE:,AZN), today ... Ventures, will broaden its focus to include areas ... therapeutic areas of,cardiovascular and metabolic disease, pain and ...
... SEC Shares Expected to be Approved ... Germany and OXFORD, England, January 7 /PRNewswire-FirstCall/,--, - ... Consolidated Financial Statements With a Positive Net Effect on,the ... 2007, Evotec AG (Frankfurt Stock Exchange: EVT) today ...
Cached Biology Technology:Cephalon Presentation Slides for the 26th Annual JPMorgan Healthcare Conference Now Available 2MedImmune Broadens Focus of Venture Capital Fund to Include New Therapeutic Areas 2MedImmune Broadens Focus of Venture Capital Fund to Include New Therapeutic Areas 3Evotec Provides Update on Planned NASDAQ Listing in the Context of its Announced Acquisition of Renovis 2Evotec Provides Update on Planned NASDAQ Listing in the Context of its Announced Acquisition of Renovis 3Evotec Provides Update on Planned NASDAQ Listing in the Context of its Announced Acquisition of Renovis 4Evotec Provides Update on Planned NASDAQ Listing in the Context of its Announced Acquisition of Renovis 5
A431 cells Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Madin-Darby bovine kidney (MDBK) cells Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
... 48 lanes, 24 bi-directional, of patient DNA ... either slab gel or capillary sequencers, using ... parameters in Explorer have been sealed to ... have built Explorer for ease of use, ...
Molecular Biological Resources offers bulk quantities of existing protein products. Please see the Chimerx divisions website for existing products and contact lloconne@molbiores.com for pricing....
Biology Products: