Navigation Links
Optimal vitamin D dosage for infants uncertain
Date:4/30/2013

in any of the groups. The 1,600-IU/d dosage was discontinued prematurely because of elevated plasma 25(OH)D concentrations."

Overall, 97 percent of infants in all treatment groups achieved the secondary outcome of 50 nmol/L or greater of plasma 25(OH)D by 3 months of age, with no differences among groups. This concentration was sustained in 98 percent of infants at 12 months.

Bone mineral concentration increased over time for lumbar spine, femur, and whole body but did not differ by group.

"Our primary objective was to establish a vitamin D dosage that would support a plasma concentration of 25(OH)D of 75 nmol/L or greater in 97.5 percent of infants at 3 months of age. Only the 1,600-IU/d dosage of vitamin D met this criterion; however, this dosage was discontinued because most infants in that group developed elevated plasma 25(OH)D concentrations that have been associated with hypercalcemia [higher-than-normal level of calcium in the blood]," the authors write. "Thus, the primary outcome was not achieved at 3 months, when plasma 25(OH)D concentrations were highest; all dosages failed except the highest dosage, which appears to be too high."

"Additional studies are required before conclusions can be made regarding higher targets or the needs of high-risk groups."

(JAMA. 2013;309(17):1785-1792; Available pre-embargo to the media at http://media.jamanetwork.com)

Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Please Note: An author podcast on this study will be available post-embargo on the JAMA website.

Editorial: Targeting Dietary Vitamin D Intakes and Plasma 25-Hydroxyvitamin D in Healthy Infants

Steven A. Abrams, M.D., of the Baylor College of Medicine, Houston, comments on the fin
'/>"/>

Contact: Hope Weiler
hope.weiler@mcgill.ca
The JAMA Network Journals
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UNC Charlotte researcher leads effort to forecast optimal energy investments
2. Vitamin E identified as potential weapon against obesity
3. Quit smoking? Vitamin E may give extra boost to heart health
4. Excess vitamin E intake not a health concern
5. Vitamin P as a potential approach for the treatment of damaged motor neurons
6. Vitamin D benefits breathing in tuberculosis patients
7. Living in a sunny climate does not improve vitamin D levels in hip fracture patients
8. Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients
9. Organic tomatoes accumulate more vitamin C, sugars than conventionally grown fruit
10. Vitamin C is beneficial against the common cold
11. African-American, Caucasian women should take identical vitamin D doses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... amount of death at the right time might actually ... research that could help in understanding animal populations, pest ... a paper in the journal Trends in Ecology ... colleagues conclude that the kind of positive population effect ... or mortality, depends on the size and developmental stage ...
(Date:11/4/2014)... , November 4, 2014   ... market growth   Fuel3D , a developer ... a funding round totaling $6.4 million (£4 million). This funding ... secured earlier this year and paves the way for the ... The funding round was led by Chimera Partners ...
(Date:11/3/2014)... of Colorado Cancer Center study published in ... Sciences describes the activity of a recently discovered ... or IL-37. It has been known to limit inflammation ... adaptive immune system: IL-37 inhibits the ability of the ... "Knowing this mechanism that underlies IL-37,s effect on the ...
Breaking Biology News(10 mins):When less is more: Death in moderation boosts population density in nature 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3PNAS: From HIV to cancer, IL-37 regulates immune system 2
... to maximise their chances of producing offspring across a ... the evolution of ejaculation strategies. The findings by researchers ... Oxford suggest that, paradoxically, matings with attractive males may ... In the paper, published in the journal ...
... Researchers from the Centers for Disease Control and Prevention ... is influenced by age of menarche and total number ... hormonal activity over the course of a woman,s lifetime ... Results of this study are published in Cancer ...
... manners to wait your turn it,s actually down to ... A study in the University,s School of Psychology sought ... species. The conclusion is that there is an "invisible hand" ... Colman and Dr Lindsay Browning carried out the study due ...
Cached Biology News:Spread your sperm the smart way 2Spread your sperm the smart way 32 reproductive factors are important predictors of death from ovarian cancer 22 reproductive factors are important predictors of death from ovarian cancer 3Research shows that 'invisible hand' guides evolution of cooperative turn-taking 2
(Date:11/22/2014)... 22, 2014 Respiratory therapy students ... proper management of life-like respiratory ailments using the ... . Grand Rapids-based, Michigan Instruments Inc. developers of ... of the respiratory simulation units to the pro-gram, ... Valley and Muskegon Community College are collaborating to ...
(Date:11/21/2014)...   TRU-D SmartUVC LLC and its UK partners, ... disinfection robot, TRU-D SmartUVC, at FIS 2014 in ... 26 at Stand 23. The conference, hosted by ... largest infection-related event of its kind and brings ... the leading events of its type throughout the world. This ...
(Date:11/21/2014)... 20, 2014 The California ... research organization representing leading California academic institutions, biotechnology, ... PwC US today released a report revealing ... industry growth. The trend shows a 4 percent ... California Biomedical Industry Report indicates that, while ...
(Date:11/21/2014)... 21, 2014 Why did Stephen Hawking ... Einstein so instantly recognizable? Why have they become icons ... and author Hilton Ratcliffe seeks out the answers to ... all to do with science. In " Stephen Hawking ... November 21, 2014), Ratcliffe puts it plainly: , ...
Breaking Biology Technology:Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 2TRU-D SmartUVC to Showcase Superbug-Killing Robot at FIS 2014 3California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 2California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 3California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 4“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 2“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 3“Stephen Hawking Smoked My Socks” Sparks Controversy in Science World 4
... (CT) and Magnetic Resonance Imaging (MRI) to investigate internal ... Images revealed, for the first time non-invasively, how a ... big meal and during digestion, until it has disappeared ... of animal anatomy could be valuable supplements to traditional ...
... 29 The California Department of Labor today awarded ... grant to implement new workforce training programs for careers ... a collaborative effort including CleanTECH San Diego, BIOCOM, San Diego ... the San Diego Workforce Partnership, captured the grant through the ...
... June 29 Genomatica announced today ... of schedule. First, the company achieved pilot-scale validation, at ... a ,green, version of 1,4-butanediol (BDO), its first commercial ... time and reduced development and production costs made possible ...
Cached Biology Technology:Feast and famine: MRI reveals secrets of animal anatomy 2San Diego Region Awarded $4 Million Workforce Development Grant to Support Expanding Biofuels Industry 2San Diego Region Awarded $4 Million Workforce Development Grant to Support Expanding Biofuels Industry 3San Diego Region Awarded $4 Million Workforce Development Grant to Support Expanding Biofuels Industry 4Genomatica Delivers Pilot-Scale Validation in Sustainable Chemical Manufacturing 2Genomatica Delivers Pilot-Scale Validation in Sustainable Chemical Manufacturing 3Genomatica Delivers Pilot-Scale Validation in Sustainable Chemical Manufacturing 4
Mouse monoclonal [1.F.1] to Yersinia pestis F1 antigen ( Abpromise for all tested applications). Antigen: Purified F1 antigen of Y. pestis vaccine strain EB....
Rabbit polyclonal to L Kynurenine ( Abpromise for all tested applications). Antigen: Synthetic peptide L Kynurenine conjugated to a protein carrier. Entrez Gene ID: 8942 Swiss Protein ID...
Rabbit polyclonal to P5 ( Abpromise for all tested applications). entrezGeneID: 10954 SwissProtID: Q14554...
anti-achaete...
Biology Products: