Navigation Links
Ontario Genomics Institute invests in validation of a novel protein interaction technology at U of T
Date:11/1/2012

TORONTO, ON, Nov. 1, 2012 - Every process in a cell is affected by interactions between proteins. Understanding how proteins react in the human body and their relationship to diseases is essential to the development of new and better targeted therapies. The Ontario Genomics Institute (OGI) is providing $100,000 through its Pre-commercialization Business Development Fund (PBDF) to the University of Toronto (U of T)'s Mammalian Membrane Two-Hybrid (MaMTH) project, which seeks to develop and commercialize a process to better understand membrane proteins in mammalian cells.

Dr. Igor Stagljar and his research team at U of T have developed a technology to analyze protein-protein interactions of mammalian integral membrane proteins. Membrane proteins, which make up approximately one-third of all proteins in a cell, are responsible for a variety of processes, making them attractive therapeutic targets. However, they are difficult to study because of their chemical complexity. This translational research tool will allow researchers to study interactions between membrane proteins of interest and how they respond to various therapeutic compounds in the context of the human cell.

"This tool has the potential to improve drug development and expand the resources available to companies developing new therapeutics," said Dr. Mark Poznansky, President and CEO, Ontario Genomics Institute. "Investment in projects like Dr. Stagljar's demonstrate OGI's commitment to fostering a vibrant life sciences community in Ontario."

Proteomic technologies such as MaMTH are increasingly playing key roles in the fields of medicine, drug discovery and molecular diagnostics. This tool has garnered attention from industry, who plan to license the technology if the project is successful. OGI's funding is essential for the development and validation necessary to make this assay commercially viable.

"We are pleased to receive this funding from OGI, which comes
'/>"/>

Contact: Christine Beyaert
cbeyaert@ontariogenomics.ca
416-673-6597
Ontario Genomics Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. New genomics study shows ancestry could help solve disease riddles
2. Physiological Genomics journal announces a major restructuring
3. 2 pioneering plant genomics efforts given a funding boost by National Science Foundation
4. ShanghaiBio Corporation Partners with Ingenuity Systems to Address Challenges in Analysis and Interpretation of Genomics Data
5. Elsevier launches new open access journal: Applied and Translational Genomics
6. The genomics symposium to boost the further development of cancer research
7. ACRG and BGI report findings from genomics research on recurrent hepatitis B virus integration
8. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
9. BGI, University of Helsinki and Wuhan University sign a MOU concerning cooperation on genomics
10. SDSCs big data expertise aiding genomics research
11. Reducing radiation: Heart Institute model shows hope for new standards worldwide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... app called TX Invasives is now available from the ... Texas at Austin for identifying harmful non-native plant, insect ... in the United States cause about $137 billion in ... crops, clog waterways, kill native plants and more. , ... for reporting where invasive species occur, we,re more likely ...
(Date:8/28/2014)... America (ESA) is pleased to announce the selection of ... Society. Honorary Membership acknowledges those who have served ESA ... the affairs of the Society that has reached an ... the ESA Governing Board and then voted on by ... the Awards Ceremony at Entomology 2014, ESA,s Annual Meeting ...
(Date:8/28/2014)... bacterial culprits that may drive inflammatory bowel diseases (IBD) ... own intestinal immune responses as a guide. , The ... Cell . , Trillions of bacteria exist within the ... the development and progression of IBD. Yet it,s thought ... a person,s susceptibility to IBD and its potential severity. ...
Breaking Biology News(10 mins):Mobile app makes ID of harmful plants, insects in Texas a snap 2Fred Baxendale selected as Honorary Member of the Entomological Society of America 2Yale study identifies possible bacterial drivers of IBD 2
... + Lomb, the global eye health company, announced today that ... unowned shares of Technolas ™ Perfect Vision GmbH (TPV), ... was established in 2009 through a joint venture between Bausch ... sell advanced refractive and cataract technologies. The deal is expected ...
... -- Four innovating life science fields to keep an ... and tissue culture. Thanks to an aging population and ... these markets are on the rise. (Photo: ... (GII) presents four innovative life science market research reports ...
... . , Methane is formed under the absence ... the sea floor. It is a much more powerful greenhouse ... this gas is inactivated before it reaches the atmosphere and ... have now proven that these microorganisms are quite picky about ...
Cached Biology News:Bausch + Lomb to Acquire Technolas Perfect Vision GmbH 2Bausch + Lomb to Acquire Technolas Perfect Vision GmbH 3Global Market for Blood Banking and Blood Products Projected to reach $43 billion by 2018; Spectrometers and Fluorometers to Reach $18.4 bn; Anticoagulants to Reach $12.9 bn; Cell and Tissue Culture Supplies to Reach $5.6 bn 2Global Market for Blood Banking and Blood Products Projected to reach $43 billion by 2018; Spectrometers and Fluorometers to Reach $18.4 bn; Anticoagulants to Reach $12.9 bn; Cell and Tissue Culture Supplies to Reach $5.6 bn 3Global Market for Blood Banking and Blood Products Projected to reach $43 billion by 2018; Spectrometers and Fluorometers to Reach $18.4 bn; Anticoagulants to Reach $12.9 bn; Cell and Tissue Culture Supplies to Reach $5.6 bn 4Strange diet for methane consuming microorganisms 2
(Date:8/28/2014)... California, USA (PRWEB) August 28, 2014 ... Department of Physics and Optical Science and Director of ... University of North Carolina at Charlotte, and co-founder and ... elected to serve as the 2015 Vice President of ... SPIE 2014 President Philip Stahl announced recent election results ...
(Date:8/28/2014)... Nevada City, CA (PRWEB) August 28, 2014 ... and sanitation products for the food processing industry, is ... conducting a side-by side comparison of the E2 soap ... Q E2 Sanitizing Foam Soap . Hand hygiene ... pathogens in the food processing environment. Six key criteria ...
(Date:8/28/2014)... August 28, 2014 Best Sanitizers, Inc., ... an alcohol-based hand sanitizer, asks food processors and food ... the hand sanitizer they’re currently using to Best Sanitizers’ ... hygiene is critical to fighting cross-contamination and the spread ... Sanitizers believes there are key criteria that make a ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 “This kit has ... to screen from 0 to 150 ppb,” said Mark Tess, ... a significant benefit to plant owners and USDA-GIPSA inspection agencies ... other commodities. Testing can take place in a matter of ... can the plant test the feed and grain before accepting ...
Breaking Biology Technology:Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3
Rabbit polyclonal to 13,14 dihydro 15 keto Prostaglandin E2 ( Abpromise for all tested applications)....
Goat polyclonal to T7 tag (Agarose) Immunogen: Goats were immunized with MASMTGGQQMG (T7) conjugated to KLH.After multiple immunizations in Freund's adjuvant, serum was collected....
Insect Cell Lysis Buffer 50 ml...
Mouse monoclonal [11C9] to Zeralenone ( Abpromise for all tested applications). Antigen: Chemical / Small Molecule conjugated to BSA: Zeralenone...
Biology Products: