Navigation Links
Olive oil component alleviates intestinal ischemia and reperfusion
Date:2/5/2013

Here's another reason why you should include olive oil in your diet: A new research report published in the Journal of Leukocyte Biology suggests that at least one compound in olive oil significantly reduces intestinal ischemia (restricted blood supply) and the resulting reperfusion injury (tissue damage caused when blood supply returns). The compound, called "oleuropein aglycone," is the most prominent polyphenol found in olive oil and could become a novel therapeutic target aimed at treating intestinal ischemia and reperfusion injury in humans. Ultimately, this research could lead to therapeutic benefits for patients with spinal cord injuries, arthritis and pleurisy, as well as those suffering from intestinal ischemia/reperfusion.

"The phenolic compounds of olive oil can reduce the secondary injury associated with intestinal damage," said Salvatore Cuzzocrea, Ph.D., a senior researcher involved in the work from the Department of Biology and Environmental Sciences at the University of Messina in Messina, Italy. "Oleuropein aglycone may be useful in the therapy of inflammation-associated disease."

To make this discovery, scientists used four groups of mice. The first group was subjected to intestinal ischemia by splanchnic arterial occlusion (SAO) followed by reperfusion. The second group was the same as the first but was also administered oleuropein aglycone. The third group of mice underwent identical surgical procedures except for SAO shock and was kept under anesthesia for the duration of the experiment. The last group was the same as the third, but was also given oleuropein aglycone. The histological structure of the gastrointestinal tract from the third group was typical of a normal architecture, but did not present any early inflammation. The ileum from animals subjected to intestinal ischemia/reperfusion injury (IRI) showed severe histological alteration with edema of the dist
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. The millennium-old olive trees of the Iberian Peninsula are younger than expected
2. Selective grazing and aversion to olive and grape leaves achieved in goats and sheep
3. Intersil Expands Precision Analog IC Offerings with Micross Components
4. UGA study reveals flu-fighting role for well-known immune component
5. Micross Components Recognized as Teledyne Electronic Manufacturing Services Manufacturer of the Year
6. Reciprocity an important component of prosocial behavior
7. Manufacturing crack-resistant lightweight components
8. Production of FRP components without release agents
9. Researchers identify new components of the epigenetic code for honey bee development
10. Dolphin hearing system component found in insects
11. Johns Hopkins researchers uncover genes at fault for cystic fibrosis-related intestinal obstruction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... The National Institutes of Health (NIH) awarded ... to develop an electrode array system that will ... works through unprecedented resolution and scale. , LLNL,s ... support President Obama,s BRAIN (Brain Research through ... effort to revolutionize our understanding of the human ...
(Date:9/30/2014)... can live in almost any aquatic environment on Earth, ... many species are pushed to the limit. The amount ... prove critical for how different species cope in the ... University of Gothenburg, published in the scientific journal ... change continues apace thanks to increasing levels of greenhouse ...
(Date:9/30/2014)... know what goes wrong with your muscles because of age, ... "normal" actually is. That,s where a new research report published ... Journal comes in. In the report, a team ... that can help scientists "see" which genes are active in ... never-before-detected gene activity and that men have approximately 400 more ...
Breaking Biology News(10 mins):NIH taps lab to develop sophisticated electrode array system to monitor brain act 2NIH taps lab to develop sophisticated electrode array system to monitor brain act 3Shape up quickly -- applies to fish, too! 2Scientists identify which genes are active in muscles of men and women 2
... OAK RIDGE, Tenn., Dec. 16, 2013 By controlling ... at the Department of Energy,s Oak Ridge National Laboratory ... solar cells, computer monitors, TV screens, eye glasses and ... structures and being able to precisely control the diameter ...
... Every year the approach of flu season sets off a ... many different strains of flu and they vary from year ... guess and tell manufacturers which variants of the flu they ... flu-related illnesses can kill 3,000 to 49,000 Americans annually, according ...
... a nucleic acid involved in protein synthesis, is widely ... expression in different organisms. The types and quantities of ... expressed, providing insight on the genes responsible for particular ... and quantitative PCR, are available for studying gene expression. ...
Cached Biology News:ORNL devises recipe to fine-tune diameter of silica rods 2Stanford researchers take a step toward developing a 'universal' flu vaccine 2Stanford researchers take a step toward developing a 'universal' flu vaccine 3Stanford researchers take a step toward developing a 'universal' flu vaccine 4A universal RNA extraction protocol for land plants 2A universal RNA extraction protocol for land plants 3
(Date:9/30/2014)... 2014 Fast, semi-automatic creation ... in documents ChemAxon , a ... services for life science research, launches ChemCurator, an ... structures from documents. Markush structures are ... generating and understanding Markush structures is a difficult ...
(Date:9/30/2014)... , Sept. 30, 2014  KemPharm, Inc., ... discovery and development of proprietary new molecular entity ... Patent and Trademark Office (USPTO) issued U.S. Patent ... entitled, "Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl ... Making and Use Thereof." The patent, ...
(Date:9/30/2014)... September 30, 2014 iLab Solutions announced ... Benchmarking study which focuses on core facility operations, ... core managers face today. , In its 4th year ... of note is the year-over-year decrease in the percentage ... appear to be feeling the constraints of this trend. ...
(Date:9/30/2014)... CT (PRWEB) September 30, 2014 ... non-profit funder of Lyme disease research at universities, today ... researchers focused on the identification, treatment and cure for ... it had received the most applications in its history—over ... , “While we were pleased to receive so ...
Breaking Biology Technology:ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2KemPharm, Inc. Receives Patent from the USPTO for Novel Prodrug of Hydromorphone, KP511 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 3Lyme Research Alliance Awards Nearly $600,000 in New Grants 2Lyme Research Alliance Awards Nearly $600,000 in New Grants 3Lyme Research Alliance Awards Nearly $600,000 in New Grants 4
... March 27 Zinsser Analytic and ThalesNano today announced ... in the territory of Germany, Switzerland and Austria."We are ... Zinsser is a leader in automation and a brand ... Ferenc Darvas, president and chairman of ThalesNano Inc. ...
... Calif., March 26 On March 18th, Frost ... diabetes research award. The award was given in recognition ... Test , which uses glycated albumin to ... body.(Photo: http://www.newscom.com/cgi-bin/prnh/20090326/LA89768 )Diabetes is one of the ...
... Microscopic World , ... Baltimore, MD (PRWEB) March 26, 2009 -- With ... the Maryland Science Center takes the same telescopic technology used to view ... is a 4,000 square foot exhibit featuring dozens of interactive components and ...
Cached Biology Technology:Zinsser Analytic and ThalesNano Collaborate on Distributing Products 2Frost & Sullivan Award Highlights Opportunity for 'Main Street' Biotech 2Cells Exhibition Opens at Maryland Science Center 2Cells Exhibition Opens at Maryland Science Center 3
Antibody specific for histone H3 acetylated at any of the five N-terminal lysine residues. Rabbit polyclonal serum. Antigen: Synthetic peptide derived from histone H3 N-terminal region, mulitpliy...
The FailSafe™ PROBES Real-Time PCR System enables rapid, precise optimization of PCR experiments in which the product is detected using fluorescent target-specific labeled probes....
NuParaffin Kit Application: Flow Cytometry Reactivity: Human...
Immunofixation Gel Kit, requires IF100 Reactivity: Human Applications: Immunofixation ...
Biology Products: